Human opioid μ-receptor A118G polymorphism may protect against central pruritus by epidural morphine for post-cesarean analgesia

Acta Anaesthesiologica Scandinavica

Volumn 54, Issue 10, 2010, Pages 1265-1269

  Tsai, F F ^a   Fan, S Z ^a   Yang, Y M ^a   Chien, K L ^a   Su, Y N ^a   Chen, L K ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BUPIVACAINE; DIPHENHYDRAMINE; LIDOCAINE; MORPHINE; MU OPIATE RECEPTOR; PROCHLORPERAZINE;

ADULT; ALLELE; ARTICLE; BLOOD SAMPLING; CESAREAN SECTION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; FEMALE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; NAUSEA; PHENOTYPE; POSTOPERATIVE PERIOD; PREGNANT WOMAN; PRIORITY JOURNAL; PRURITUS; SINGLE NUCLEOTIDE POLYMORPHISM; URINE RETENTION; VOMITING;

ADULT; ANALGESICS, OPIOID; ANESTHESIA, EPIDURAL; ANESTHESIA, OBSTETRICAL; CESAREAN SECTION; COHORT STUDIES; DNA; EXONS; FEMALE; GENOTYPE; HUMANS; MORPHINE; PAIN, POSTOPERATIVE; POLYMORPHISM, GENETIC; PREGNANCY; PRURITUS; RECEPTORS, OPIOID, MU; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78650185666     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2010.02310.x     Document Type: Article

References (31)

1. Lim Y, Jha S, Sia AT, Rawal N. Morphine for post-caesarean section analgesia: intrathecal, epidural or intravenous? Singapore Med J 2005;46:392-66.
2. Kalow W. Pharmacogenetics in biological perspective. Pharmacol Rev 1997;49:369-79.
3. Shi MM, Bleavins MR, de la iglesia FA. Technologies for detecting genetic polymorphisms in pharmacogenomics. Mol Diagn 1999;4:343-51.
4. Tyagi S, Bratu DP, Kramer FR. Multicolor molecular beacons for allele discrimination. Nat Biotechnol 1998;16:49-53.
5. Chaney MA. Side effects of intrathecal and epidural opioids. Can J Anaesth 1995;42:891-903.
6. Lötsch J, Zimmermann M, Darimont J, Marx C, Dudziak R, Skarke C, Geisslinger G. Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity? Anesthesiology 2002;97:814-9.
7. Schworer H, Ramadori G. Improvement of cholestatic pruritus by ondansetron. Lancet 1993;341:1277.
8. Raderer M, Muller C, Scheithauer W. Ondansetron for pruritus due to cholestasis. N Engl J Med 1994;330:1540.
9. Balaskas EV, Bamihas GI, Karamouzis M, Voyiatzis G, Tourkantonis A. Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients. Nephron 1998;78:395-402.
10. Fuller JG, McMorland GH, Douglas MJ, Palmer L. Epidural morphine for analgesia after caesarean section: a report of 4880 patients. Can J Anaesth 1990;37:636-40.
11. Crighton IM, Hobbs GJ, Reid MF. Ondansetron for the treatment of pruritus after spinal opioids. Anaesthesia 1996;51:199-200.
12. Larijani GE, Goldberg ME, Rogers KH. Treatment of opioid-induced pruritus with ondansetron: report of four patients. Pharmacotherapy 1996;16:958-60.
13. Borgeat A, Stirnemann HR. Ondansetron is effective to treat spinal or epidural morphine-induced pruritus. Anesthesiology 1999;90:432-6.
14. Sarvela PJ, Halonen PM, Soikkeli AI, Kainu JP, Korttila KT. Ondansetron and tropisetron do not prevent intraspinal morphine-and fentanyl-induced pruritus in elective cesarean delivery. Acta Anaesthesiol Scand 2006;50:239-44.
15. Sheen MJ, Ho ST, Lee CH, Tsung YC, Chang FL, Huang ST. Prophylactic mirtazapine reduces intrathecal morphineinduced pruritus. Br J Anaesth 2008;101:711-5.
16. Siddik-Sayyid SM, Yazbeck-Karam VG, Zahreddine BW, Adham AM, Dagher CM, Saasouh WA, Aouad MT. Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. Acta Anaesthesiol Scand 2010;54:764-9.
17. Chou WY, Yang LC, Lu HF, Ko JY, Wang CH, Lin SH, Lee TH, Concejero A, Hsu CJ. Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty. Acta Anaesthesiol Scand 2006;50:787-92.
18. Sia AT, Lim Y, Lim EC, Sia AT, Lim Y, Lim EC, Goh RW, Law HY, Landau R, Teo YY, Tan EC. A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia. Anesthesiology 2008;109:520-6.
19. Bond C, La Forge KS, Tian M, Melia D, Zhang S, Borg L, Gong J, Schluger J, Strong JA, Leal SM, Tischfield JA, Kreek MJ, Yu L. Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci USA 1998;95:9608-13.
20. Chong RY, Oswald L, Yang X, Uhart M, Lin PI, Wand GS. The Micro-opioid receptor polymorphism A118G predicts cortisol responses to naloxone and stress. Neuropsychopharm 2006;1:204-11.
21. Lötsch J, Geisslinger G, Tegeder I. Genetic modulation of the pharmacological treatment of pain. Pharmacol Ther 2009;124:168-84.
22. Klepstad P, Rakvag TT, Kaasa S, Holthe M, Dale O, Borchgrevink PC, Baar C, Vikan T, Krokan HE, Skorpen F. The 118A 4G polymorphism in the human mu-opiod receptor gene may increase morphine requirements in patients with pain caused by malignant disease. Acta Anaesthesiol Scand 2004;48:1232-9.
23. Paus R, Schmelz M, Biro T, Steinhoff M. Frontiers in pruritus research: scratching the brain for more effective itch therapy. J Clin Invest 2006;116:1174-86.
24. Langer MD, Maiback HI. Pruritus measurement and treatment. Clin Exp Derm 2009;34:285-8.
25. Majeski CJ, Johnson JA, Davison SN, Lauzon GJ. Itch Severity Scale: a self-report insturment for the measurement of pruritus severity. Clin Lab Invest 2006;156:667-73.
26. Walter C, Lötsch J. Meta-analysis of the relevance of the OPRM1 118A 4G genetic variant for pain treatment. Pain 2009;146:270-5.
27. Wei LX, Floreani A, Variola A, El Younis C, Bergasa NV. A study of the mu opioid receptor gene polymorphism A118G in patients with primary biliary cirrhosis with and without pruritus. Acta Derm Venereol 2008;88:323-6.
28. Tan EC, Lim EC, Teo YY, Lim Y, Law HY, Sia AT. Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for post-operative pain. Mol Pain 2009;5:32.
29. Huang CJ, Liu HF, Su NY, Hsu YW, Yang CH, Chen CC, Tsai PS. Association between human opioid receptor genes polymorphisms and pressure pain sensitivity in females. Anaesthesia 2008;63:1288-95.
30. Bromage PR, Camporesi EM, Durant PA, Nielsen CH. Nonrespiratory side effects of epidural morphine. Anesth Analg 1982;61:490-5.
31. Vincent RD Jr, Chestnut DH, Choi WW, Ostman PL, Bates JN. Does epidural fentanyl decrease the efficacy of epidural morphine after cesarean delivery? Anesth Analg 1992;74:658-63.