Effect of μ-opioid receptor A118G polymorphism on the ED50 of epidural sufentanil for labor analgesia

International Journal of Obstetric Anesthesia

Volumn 21, Issue 1, 2012, Pages 40-44

  Camorcia, M ^a   Capogna, G ^a   Stirparo, S ^a   Berritta, C ^a   Blouin, J L ^b   Landau, R ^c  

^a Citta di Roma Hospital   (Italy)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

opioid receptor; Epidural; Labor analgesia; Polymorphism; Sufentanil

Indexed keywords

MU OPIATE RECEPTOR; SUFENTANIL;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; EPIDURAL ANESTHESIA; FEMALE; GENOTYPE; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; NULLIPARA; OBSTETRIC ANALGESIA; SINGLE NUCLEOTIDE POLYMORPHISM; VISUAL ANALOG SCALE;

ADULT; ANALGESIA, EPIDURAL; ANALGESIA, OBSTETRICAL; ANALGESICS, OPIOID; DOUBLE-BLIND METHOD; FEMALE; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; RECEPTORS, OPIOID, MU; SUFENTANIL;

EID: 84855830042     PISSN: 0959289X     EISSN: 15323374     Source Type: Journal    
DOI: 10.1016/j.ijoa.2011.10.001     Document Type: Article

References (15)

1. C. Walter, and J. Lotsch Meta-analysis of the relevance of the OPRM1 118A>G genetic variance for pain treatment Pain 146 2009 270 275
2. K. Befort, D. Filliol, F.M. Decaillot, C. Gaveriaux-Ruff, M.R. Hoeche, and B.L. Kieffer A single nucleotide polymorphic mutation in the human μ-opioid receptor severely impairs receptor signaling J Biol Chem 276 2001 3130 3137
3. C. Gaveriaux-Ruff, and B.L. Kieffer Opioid receptor genes inactivated in mice. the highlights Neuropeptides 36 2002 62 71
4. B.L. Kieffer, and C. Gaveriaux-Ruff Exploring the opioid system by gene knockout ProgNeurobiol 66 2002 285 306 (Pubitemid 34518287)
5. W.E. Evans, and M.V. Relling Pharmacogenomics: translating functional genomics into rational therapeutics Science 5439 1999 487 491
6. R.B. Fillingim, L. Kaplan, and R. Staud The A118G single nucleotide polymorphism of the μ-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans J Pain 6 2005 159 167 (Pubitemid 40365019)
7. R. Landau, A. Cahana, R.M. Smiley, S.E. Antonarakis, and J.L. Blouin Genetic variability of μ-opioid receptor in an obstetric population Anesthesiology 100 2004 1030 1033 (Pubitemid 38392598)
8. R. Landau, C. Kern, M. Columb, R.M. Smiley, and J.L. Blouin Genetic variability of the μ-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women Pain 139 2008 5 14
9. C.A. Wong, R.J. McCarthy, J. Blouin, and R. Landau Observational study of the effect of μ-opioid receptor genetic polymorphism on intrathecal opioids labor analgesia and post-cesarean delivery analgesia Int J Obstet Anesth 19 2010 246 253
10. N.R. Connelly, R.K. Parker, V. Vallurupalli, S. Bhopatkar, and S. Dunn Comparison of epidural fentanyl versus epidural sufentanil for analgesia in ambulatory patients in early labor Anesth Analg 91 2000 374 378 (Pubitemid 30624300)
11. W. Dixon, and F. Massey Introduction to Statistical Analysis vol. 4 1983 McGraw-Hill New York p. 428-39
12. G. Capogna, R. Parpaglioni, G. Lyons, M. Columb, and D. Celleno Minimum analgesic dose of epidural sufentanil for first stage labor analgesia Anesthesiology 94 2001 740 744
13. W. Margas, I. Zubko, H.G. Schuler, P.K. Janicki, and V. Ruiz-Velasco Modulation of Ca2+ channels by heterologously expressed wild type and mutant micro-opioid receptor (hMORs) containing the A118G single nucleotide polymorphism J Neurophysiol 97 2007 1058 1067 (Pubitemid 46239487)
14. W.R. Camann, R.A. Denney, E.D. Holby, and S. Datta A comparison of intrathecal, epidural and intravenous sufentanil for labor analgesia Anesthesiology 77 1992 884 887
15. G. Capogna, M. Camorcia, and M.O. Columb Minimum analgesic doses of fentanyl and sufentanil for epidural analgesia in the first stage of labor Anesth Analg 96 2003 1178 1182 (Pubitemid 36359063)