-
1
-
-
78650121847
-
Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies
-
Bernardo BC, Weeks KL, Pretorius L, McMullen JR. Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies. Pharmacol. Ther. 128(1), 191-227 (2010
-
(2010)
Pharmacol. Ther
, vol.128
, Issue.1
, pp. 191-227
-
-
Bernardo, B.C.1
Weeks, K.L.2
Pretorius, L.3
McMullen, J.R.4
-
2
-
-
84857506068
-
A microRNA guide for clinicians and basic scientists: Background and experimental techniques
-
Bernardo BC, Charchar FJ, Lin RC, McMullen JR. A microRNA guide for clinicians and basic scientists: Background and experimental techniques. Heart Lung Circ. 21(3), 131-142 (2012
-
(2012)
Heart Lung Circ
, vol.21
, Issue.3
, pp. 131-142
-
-
Bernardo, B.C.1
Charchar, F.J.2
Lin, R.C.3
McMullen, J.R.4
-
3
-
-
0030219688
-
Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development
-
Li F, Wang X, Capasso JM, Gerdes AM. Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development. J. Mol. Cell. Cardiol. 28(8), 1737-1746 (1996
-
(1996)
J. Mol. Cell. Cardiol
, vol.28
, Issue.8
, pp. 1737-1746
-
-
Li, F.1
Wang, X.2
Capasso, J.M.3
Gerdes, A.M.4
-
4
-
-
33750734736
-
Cardiomyocyte DNA synthesis and binucleation during murine development
-
Pt2
-
Soonpaa MH, Kim KK, Pajak L, Franklin M, Field LJ. Cardiomyocyte DNA synthesis and binucleation during murine development. Am. J. Physiol. 271(5 Pt 2), H2183-H2189 (1996
-
(1996)
Am. J. Physiol
, vol.271
, Issue.5
-
-
Soonpaa, M.H.1
Kim, K.K.2
Pajak, L.3
Franklin, M.4
Field, L.J.5
-
5
-
-
77952371023
-
Cardiomyocyte cell cycle control and growth estimation in vivo - Analysis based on cardiomyocyte nuclei
-
Walsh S, Ponten A, Fleischmann BK, Jovinge S. Cardiomyocyte cell cycle control and growth estimation in vivo - Analysis based on cardiomyocyte nuclei. Cardiovasc. Res. 86(3), 365-373 (2010
-
(2010)
Cardiovasc. Res
, vol.86
, Issue.3
, pp. 365-373
-
-
Walsh, S.1
Ponten, A.2
Fleischmann, B.K.3
Jovinge, S.4
-
6
-
-
79955161098
-
The athletés heart vs the failing heart: Can signaling explain the two distinct outcomes?
-
Weeks KL, McMullen JR. The athletés heart vs. the failing heart: Can signaling explain the two distinct outcomes? Physiology (Bethesda) 26(2), 97-105 (2011
-
(2011)
Physiology (Bethesda)
, vol.26
, Issue.2
, pp. 97-105
-
-
Weeks, K.L.1
McMullen, J.R.2
-
7
-
-
0034213075
-
The conserved phosphoinositide 3-kinase pathway determines heart size in mice
-
Shioi T, Kang PM, Douglas PS et al. The conserved phosphoinositide 3-kinase pathway determines heart size in mice. EMBO J. 19(11), 2537-2548 (2000
-
(2000)
EMBO J.
, vol.19
, Issue.11
, pp. 2537-2548
-
-
Shioi, T.1
Kang, P.M.2
Douglas, P.S.3
-
8
-
-
0142027759
-
Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy
-
McMullen JR, Shioi T, Zhang L et al. Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy. Proc. Natl Acad. Sci. USA 100(21), 12355-12360 (2003
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.21
, pp. 12355-12360
-
-
McMullen, J.R.1
Shioi, T.2
Zhang, L.3
-
9
-
-
84864621624
-
Phosphoinositide 3-kinase p110alpha is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction
-
Weeks KL, Gao X, Du XJ et al. Phosphoinositide 3-kinase p110alpha is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction. Circ. Heart Fail. 5(4), 523-534 (2012
-
(2012)
Circ. Heart Fail
, vol.5
, Issue.4
, pp. 523-534
-
-
Weeks, K.L.1
Gao, X.2
Du, X.J.3
-
10
-
-
33646449520
-
Akt1 is required for physiological cardiac growth
-
DeBosch B, Treskov I, Lupu TS et al. Akt1 is required for physiological cardiac growth. Circulation 113(17), 2097-2104 (2006
-
(2006)
Circulation
, vol.113
, Issue.17
, pp. 2097-2104
-
-
DeBosch, B.1
Treskov, I.2
Lupu, T.S.3
-
11
-
-
84862067303
-
Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation
-
Chung E, Yeung F, Leinwand LA. Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation. J. Appl. Physiol. 112(9), 1564-1575 (2012
-
(2012)
J. Appl. Physiol
, vol.112
, Issue.9
, pp. 1564-1575
-
-
Chung, E.1
Yeung, F.2
Leinwand, L.A.3
-
12
-
-
84887929194
-
Calcineurin activity is required for cardiac remodelling in pregnancy
-
Chung E, Yeung F, Leinwand LA. Calcineurin activity is required for cardiac remodelling in pregnancy. Cardiovasc. Res. 100(3), 402-410 (2013
-
(2013)
Cardiovasc. Res
, vol.100
, Issue.3
, pp. 402-410
-
-
Chung, E.1
Yeung, F.2
Leinwand, L.A.3
-
13
-
-
36148960465
-
Hypertrophy signaling during peripartum cardiac remodeling
-
Gonzalez AM, Osorio JC, Manlhiot C, Gruber D, Homma S, Mital S. Hypertrophy signaling during peripartum cardiac remodeling. Am. J. Physiol. Heart Circ. Physiol. 293(5), H3008-H3013 (2007
-
(2007)
Am. J. Physiol. Heart Circ. Physiol
, vol.293
, Issue.5
-
-
Gonzalez, A.M.1
Osorio, J.C.2
Manlhiot, C.3
Gruber, D.4
Homma, S.5
Mital, S.6
-
14
-
-
33846815521
-
A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy
-
Hilfiker-Kleiner D, Kaminski K, Podewski E et al. A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy. Cell 128(3), 589-600 (2007
-
(2007)
Cell
, vol.128
, Issue.3
, pp. 589-600
-
-
Hilfiker-Kleiner, D.1
Kaminski, K.2
Podewski, E.3
-
15
-
-
79955052182
-
Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy
-
Lemmens K, Doggen K, De Keulenaer GW. Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy. Am. J. Physiol. Heart Circ. Physiol. 300(3), H931-H942 (2011
-
(2011)
Am. J. Physiol. Heart Circ. Physiol
, vol.300
, Issue.3
-
-
Lemmens, K.1
Doggen, K.2
De Keulenaer, G.W.3
-
16
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116(2), 281-297 (2004
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 281-297
-
-
Bartel, D.P.1
-
18
-
-
0027751663
-
The C elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75(5), 843-854 (1993
-
(1993)
Cell
, vol.75
, Issue.5
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
19
-
-
0027730383
-
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C elegans
-
Wightman B, Ha I, Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75(5), 855-862 (1993
-
(1993)
Cell
, vol.75
, Issue.5
, pp. 855-862
-
-
Wightman, B.1
Ha, I.2
Ruvkun, G.3
-
20
-
-
79960104144
-
MicroRNAs in development and disease
-
Sayed D, Abdellatif M. MicroRNAs in development and disease. Physiol. Rev. 91(3), 827-887 (2011
-
(2011)
Physiol. Rev
, vol.91
, Issue.3
, pp. 827-887
-
-
Sayed, D.1
Abdellatif, M.2
-
21
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120(1), 15-20 (2005
-
(2005)
Cell
, vol.120
, Issue.1
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
22
-
-
41149147013
-
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
-
Chen JF, Murchison EP, Tang R et al. Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc. Natl Acad. Sci. USA 105(6), 2111-2116 (2008
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.6
, pp. 2111-2116
-
-
Chen, J.F.1
Murchison, E.P.2
Tang, R.3
-
23
-
-
55249125659
-
Conditional dicer gene deletion in the postnatal myocardium provokes spontaneous cardiac remodeling
-
da Costa Martins PA, Bourajjaj M, Gladka M et al. Conditional dicer gene deletion in the postnatal myocardium provokes spontaneous cardiac remodeling. Circulation 118(15), 1567-1576 (2008
-
(2008)
Circulation
, vol.118
, Issue.15
, pp. 1567-1576
-
-
Da Costa Martins, P.A.1
Bourajjaj, M.2
Gladka, M.3
-
24
-
-
84857990043
-
MicroRNAs in control of cardiac hypertrophy
-
Da Costa Martins PA, De Windt LJ. MicroRNAs in control of cardiac hypertrophy. Cardiovasc. Res. 93(4), 563-572 (2012
-
(2012)
Cardiovasc. Res
, vol.93
, Issue.4
, pp. 563-572
-
-
Da Costa Martins, P.A.1
De Windt, L.J.2
-
25
-
-
84874967223
-
Role of microRNAs in cardiac remodelling: New insights and future perspectives
-
Orenes-Pinero E, Montoro-Garcia S, Patel JV, Valdes M, Marin F, Lip GY. Role of microRNAs in cardiac remodelling: New insights and future perspectives. Int. J. Cardiol. 167(5), 1651-1659 (2012
-
(2012)
Int. J. Cardiol
, vol.167
, Issue.5
, pp. 1651-1659
-
-
Orenes-Pinero, E.1
Montoro-Garcia, S.2
Patel, J.V.3
Valdes, M.4
Marin, F.5
Lip, G.Y.6
-
26
-
-
34547579291
-
MicroRNAs in the human heart: A clue to fetal gene reprogramming in heart failure
-
Thum T, Galuppo P, Wolf C et al. MicroRNAs in the human heart: A clue to fetal gene reprogramming in heart failure. Circulation 116(3), 258-267 (2007
-
(2007)
Circulation
, vol.116
, Issue.3
, pp. 258-267
-
-
Thum, T.1
Galuppo, P.2
Wolf, C.3
-
27
-
-
33846318098
-
Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy
-
McMullen JR, Amirahmadi F, Woodcock EA et al. Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy. Proc. Natl Acad. Sci. USA 104(2), 612-617 (2007
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.2
, pp. 612-617
-
-
McMullen, J.R.1
Amirahmadi, F.2
Woodcock, E.A.3
-
28
-
-
13444306209
-
Pregnancy alters nitric oxide synthase and natriuretic peptide systems in the rat left ventricle
-
Jankowski M, Wang D, Mukaddam-Daher S, Gutkowska J. Pregnancy alters nitric oxide synthase and natriuretic peptide systems in the rat left ventricle. J. Endocrinol. 184(1), 209-217 (2005
-
(2005)
J. Endocrinol
, vol.184
, Issue.1
, pp. 209-217
-
-
Jankowski, M.1
Wang, D.2
Mukaddam-Daher, S.3
Gutkowska, J.4
-
29
-
-
34249279050
-
MicroRNA-133 controls cardiac hypertrophy
-
Care A, Catalucci D, Felicetti F et al. MicroRNA-133 controls cardiac hypertrophy. Nat. Med. 13(5), 613-618 (2007
-
(2007)
Nat. Med
, vol.13
, Issue.5
, pp. 613-618
-
-
Care, A.1
Catalucci, D.2
Felicetti, F.3
-
30
-
-
79959312396
-
MicroRNAs 29 are involved in the improvement of ventricular compliance promoted by aerobic exercise training in rats
-
Soci UP, Fernandes T, Hashimoto NY et al. MicroRNAs 29 are involved in the improvement of ventricular compliance promoted by aerobic exercise training in rats. Physiol. Genomics 43(11), 665-673 (2011
-
(2011)
Physiol. Genomics
, vol.43
, Issue.11
, pp. 665-673
-
-
Soci, U.P.1
Fernandes, T.2
Hashimoto, N.Y.3
-
31
-
-
51349141401
-
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
-
van Rooij E, Sutherland LB, Thatcher JE et al. Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc. Natl Acad. Sci. USA 105(35), 13027-13032 (2008
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.35
, pp. 13027-13032
-
-
Van Rooij, E.1
Sutherland, L.B.2
Thatcher, J.E.3
-
32
-
-
80051473367
-
Aerobic exercise training-induced left ventricular hypertrophy involves regulatory microRNAs, decreased angiotensin-converting enzyme-Angiotensin ii, and synergistic regulation of angiotensin-converting enzyme 2-Angiotensin (1-7)
-
Fernandes T, Hashimoto NY, Magalhaes FC et al. Aerobic exercise training-induced left ventricular hypertrophy involves regulatory microRNAs, decreased angiotensin-converting enzyme-Angiotensin ii, and synergistic regulation of angiotensin-converting enzyme 2-Angiotensin (1-7). Hypertension 58(2), 182-189 (2011
-
(2011)
Hypertension
, vol.58
, Issue.2
, pp. 182-189
-
-
Fernandes, T.1
Hashimoto, N.Y.2
Magalhaes, F.C.3
-
33
-
-
33846987938
-
Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7)
-
Grobe JL, Mecca AP, Lingis M et al. Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7). Am. J. Physiol. Heart Circ. Physiol. 292(2), H736-H742 (2007
-
(2007)
Am. J. Physiol. Heart Circ. Physiol
, vol.292
, Issue.2
-
-
Grobe, J.L.1
Mecca, A.P.2
Lingis, M.3
-
34
-
-
34547951695
-
ACE2: A new target for cardiovascular disease therapeutics
-
Raizada MK, Ferreira AJ. ACE2: A new target for cardiovascular disease therapeutics. J. Cardiovasc. Pharmacol. 50(2), 112-119 (2007
-
(2007)
J. Cardiovasc. Pharmacol
, vol.50
, Issue.2
, pp. 112-119
-
-
Raizada, M.K.1
Ferreira, A.J.2
-
35
-
-
58149352445
-
Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart
-
Mercure C, Yogi A, Callera GE et al. Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart. Circ. Res. 103(11), 1319-1326 (2008
-
(2008)
Circ. Res
, vol.103
, Issue.11
, pp. 1319-1326
-
-
Mercure, C.1
Yogi, A.2
Callera, G.E.3
-
36
-
-
77949478630
-
Brain renin-Angiotensin system: Fetal epigenetic programming by maternal protein restriction during pregnancy
-
Goyal R, Goyal D, Leitzke A, Gheorghe CP, Longo LD. Brain renin-Angiotensin system: Fetal epigenetic programming by maternal protein restriction during pregnancy. Reprod. Sci. 17(3), 227-238 (2010
-
(2010)
Reprod. Sci
, vol.17
, Issue.3
, pp. 227-238
-
-
Goyal, R.1
Goyal, D.2
Leitzke, A.3
Gheorghe, C.P.4
Longo, L.D.5
-
37
-
-
70349213385
-
Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster
-
Boettger T, Beetz N, Kostin S et al. Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J. Clin. Invest. 119(9), 2634-2647 (2009
-
(2009)
J. Clin. Invest
, vol.119
, Issue.9
, pp. 2634-2647
-
-
Boettger, T.1
Beetz, N.2
Kostin, S.3
-
38
-
-
84863981799
-
Swimming training in rats increases cardiac MicroRNA-126 expression and angiogenesis
-
Silva ND Jr, Fernandes T, Soci UP, Monteiro AW, Phillips MI, DE Oliveira EM. Swimming training in rats increases cardiac MicroRNA-126 expression and angiogenesis. Med. Sci. Sports Exerc. 44(8), 1453-1462 (2012
-
(2012)
Med. Sci. Sports Exerc
, vol.44
, Issue.8
, pp. 1453-1462
-
-
Silva Jr., N.D.1
Fernandes, T.2
Soci, U.P.3
Monteiro, A.W.4
Phillips, M.I.5
Oliveira, E.M.6
-
39
-
-
60849106298
-
Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126
-
Kuhnert F, Mancuso MR, Hampton J et al. Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126. Development 135(24), 3989-3993 (2008
-
(2008)
Development
, vol.135
, Issue.24
, pp. 3989-3993
-
-
Kuhnert, F.1
Mancuso, M.R.2
Hampton, J.3
-
40
-
-
48549106378
-
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis
-
Wang S, Aurora AB, Johnson BA et al. The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. Dev. Cell 15(2), 261-271 (2008
-
(2008)
Dev. Cell
, vol.15
, Issue.2
, pp. 261-271
-
-
Wang, S.1
Aurora, A.B.2
Johnson, B.A.3
-
41
-
-
84884675385
-
Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway
-
Ma Z, Qi J, Meng S, Wen B, Zhang J. Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway. Eur. J. Appl. Physiol. 113(10), 2473-2486 (2013
-
(2013)
Eur. J. Appl. Physiol
, vol.113
, Issue.10
, pp. 2473-2486
-
-
Ma, Z.1
Qi, J.2
Meng, S.3
Wen, B.4
Zhang, J.5
-
42
-
-
77950871530
-
PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: Identification of PI3K-regulated miRNA and mRNA
-
Lin RC, Weeks KL, Gao XM et al. PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: Identification of PI3K-regulated miRNA and mRNA. Arterioscler. Thromb. Vasc. Biol. 30(4), 724-732 (2010
-
(2010)
Arterioscler. Thromb. Vasc. Biol
, vol.30
, Issue.4
, pp. 724-732
-
-
Lin, R.C.1
Weeks, K.L.2
Gao, X.M.3
-
43
-
-
84867903854
-
Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function
-
Bernardo BC, Gao XM, Winbanks CE et al. Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function. Proc. Natl Acad. Sci. USA 109(43), 17615-17620 (2012
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, Issue.43
, pp. 17615-17620
-
-
Bernardo, B.C.1
Gao, X.M.2
Winbanks, C.E.3
-
44
-
-
0037125980
-
Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice
-
Condorelli G, Drusco A, Stassi G et al. Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc. Natl Acad. Sci. USA 99(19), 12333-12338 (2002
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, Issue.19
, pp. 12333-12338
-
-
Condorelli, G.1
Drusco, A.2
Stassi, G.3
-
45
-
-
80052557916
-
MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes
-
Porrello ER, Johnson BA, Aurora AB et al. MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes. Circ. Res. 109(6), 670-679 (2011
-
(2011)
Circ. Res
, vol.109
, Issue.6
, pp. 670-679
-
-
Porrello, E.R.1
Johnson, B.A.2
Aurora, A.B.3
-
46
-
-
84880040358
-
Mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts
-
Chen J, Huang ZP, Seok HY et al. mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circ. Res. 112(12), 1557-1566 (2013
-
(2013)
Circ. Res
, vol.112
, Issue.12
, pp. 1557-1566
-
-
Chen, J.1
Huang, Z.P.2
Seok, H.Y.3
-
47
-
-
84859762591
-
A novel cardiomyocyte-enriched microRNA, miR-378, targets insulin-like growth factor 1 receptor: Implications in postnatal cardiac remodeling and cell survival
-
Knezevic I, Patel A, Sundaresan NR et al. A novel cardiomyocyte-enriched microRNA, miR-378, targets insulin-like growth factor 1 receptor: Implications in postnatal cardiac remodeling and cell survival. J. Biol.Chem. 287(16), 12913-12926 (2012
-
(2012)
J. Biol.Chem
, vol.287
, Issue.16
, pp. 12913-12926
-
-
Knezevic, I.1
Patel, A.2
Sundaresan, N.R.3
-
48
-
-
84878294979
-
MiR-378 controls cardiac hypertrophy by combined repression of mitogen-Activated protein kinase pathway factors
-
Ganesan J, Ramanujam D, Sassi Y et al. MiR-378 controls cardiac hypertrophy by combined repression of mitogen-Activated protein kinase pathway factors. Circulation 127(21), 2097-2106 (2013
-
(2013)
Circulation
, vol.127
, Issue.21
, pp. 2097-2106
-
-
Ganesan, J.1
Ramanujam, D.2
Sassi, Y.3
-
49
-
-
84877116748
-
MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy
-
Halkein J, Tabruyn SP, Ricke-Hoch M et al. MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy. J. Clin. Invest. 123(5), 2143-2154 (2013
-
(2013)
J. Clin. Invest
, vol.123
, Issue.5
, pp. 2143-2154
-
-
Halkein, J.1
Tabruyn, S.P.2
Ricke-Hoch, M.3
-
50
-
-
84868475728
-
MicroRNA therapeutics for cardiovascular disease: Opportunities and obstacles
-
van Rooij E, Olson EN. MicroRNA therapeutics for cardiovascular disease: Opportunities and obstacles. Nat. Rev. Drug Discov. 11(11), 860-872 (2012
-
(2012)
Nat. Rev. Drug Discov
, vol.11
, Issue.11
, pp. 860-872
-
-
Van Rooij, E.1
Olson, E.N.2
-
51
-
-
40249106014
-
Antagonism of microRNA-122 in mice by systemically administered LNA-AntimiR leads to up-regulation of a large set of predicted target mRNAs in the liver
-
Elmen J, Lindow M, Silahtaroglu A et al. Antagonism of microRNA-122 in mice by systemically administered LNA-AntimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res. 36(4), 1153-1162 (2008
-
(2008)
Nucleic Acids Res
, vol.36
, Issue.4
, pp. 1153-1162
-
-
Elmen, J.1
Lindow, M.2
Silahtaroglu, A.3
-
52
-
-
42249093319
-
LNA-mediated microRNA silencing in non-human primates
-
Elmen J, Lindow M, Schutz S et al. LNA-mediated microRNA silencing in non-human primates. Nature 452(7189), 896-899 (2008
-
(2008)
Nature
, vol.452
, Issue.7189
, pp. 896-899
-
-
Elmen, J.1
Lindow, M.2
Schutz, S.3
-
53
-
-
84877258007
-
Treatment of HCV infection by targeting microRNA
-
Janssen HL, Reesink HW, Lawitz EJ et al. Treatment of HCV infection by targeting microRNA. N. Engl. J. Med. 368(18), 1685-1694 (2013
-
(2013)
N. Engl. J. Med
, vol.368
, Issue.18
, pp. 1685-1694
-
-
Janssen, H.L.1
Reesink, H.W.2
Lawitz, E.J.3
-
54
-
-
84858782897
-
Inhibition of microRNA function by antimiR oligonucleotides
-
Stenvang J, Petri A, Lindow M, Obad S, Kauppinen S. Inhibition of microRNA function by antimiR oligonucleotides. Silence 3(1), 1 (2012
-
(2012)
Silence
, vol.3
, Issue.1
, pp. 1
-
-
Stenvang, J.1
Petri, A.2
Lindow, M.3
Obad, S.4
Kauppinen, S.5
-
55
-
-
34250679405
-
Specificity, duplex degradation and subcellular localization of antagomirs
-
Krutzfeldt J, Kuwajima S, Braich R et al. Specificity, duplex degradation and subcellular localization of antagomirs. Nucleic Acids Res. 35(9), 2885-2892 (2007
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.9
, pp. 2885-2892
-
-
Krutzfeldt, J.1
Kuwajima, S.2
Braich, R.3
-
56
-
-
79953202455
-
Silencing of microRNA families by seed-Targeting tiny LNAs
-
Obad S, dos Santos CO, Petri A et al. Silencing of microRNA families by seed-Targeting tiny LNAs. Nat. Genet. 43(4), 371-378 (2011
-
(2011)
Nat. Genet
, vol.43
, Issue.4
, pp. 371-378
-
-
Obad, S.1
Dos Santos, C.O.2
Petri, A.3
-
57
-
-
33645075443
-
MiR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
-
Esau C, Davis S, Murray SF et al. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab. 3(2), 87-98 (2006
-
(2006)
Cell Metab
, vol.3
, Issue.2
, pp. 87-98
-
-
Esau, C.1
Davis, S.2
Murray, S.F.3
-
58
-
-
84874700585
-
MicroRNA-34a regulates cardiac ageing and function
-
Boon RA, Iekushi K, Lechner S et al. MicroRNA-34a regulates cardiac ageing and function. Nature 495(7439), 107-110 (2013
-
(2013)
Nature
, vol.495
, Issue.7439
, pp. 107-110
-
-
Boon, R.A.1
Iekushi, K.2
Lechner, S.3
-
59
-
-
57749168828
-
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
-
Thum T, Gross C, Fiedler J et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 456(7224), 980-984 (2008
-
(2008)
Nature
, vol.456
, Issue.7224
, pp. 980-984
-
-
Thum, T.1
Gross, C.2
Fiedler, J.3
-
60
-
-
80054971110
-
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
-
Rayner KJ, Esau CC, Hussain FN et al. Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. Nature 478(7369), 404-407 (2011
-
(2011)
Nature
, vol.478
, Issue.7369
, pp. 404-407
-
-
Rayner, K.J.1
Esau, C.C.2
Hussain, F.N.3
-
61
-
-
80053567152
-
Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure/clinical perspective
-
Montgomery RL, Hullinger TG, Semus HM et al. Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure/clinical perspective. Circulation 124(14), 1537-1547 (2011
-
(2011)
Circulation
, vol.124
, Issue.14
, pp. 1537-1547
-
-
Montgomery, R.L.1
Hullinger, T.G.2
Semus, H.M.3
-
62
-
-
74249112787
-
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
-
Lanford RE, Hildebrandt-Eriksen ES, Petri A et al. Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327(5962), 198-201 (2010
-
(2010)
Science
, vol.327
, Issue.5962
, pp. 198-201
-
-
Lanford, R.E.1
Hildebrandt-Eriksen, E.S.2
Petri, A.3
-
63
-
-
84871992154
-
Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family
-
Porrello ER, Mahmoud AI, Simpson E et al. Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family. Proc. Natl Acad. Sci. USA 110(1), 187-192 (2013
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, Issue.1
, pp. 187-192
-
-
Porrello, E.R.1
Mahmoud, A.I.2
Simpson, E.3
-
64
-
-
28444469246
-
Silencing of microRNAs in vivo with antagomirs
-
Krutzfeldt J, Rajewsky N, Braich R et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 438(7068), 685-689 (2005
-
(2005)
Nature
, vol.438
, Issue.7068
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
-
65
-
-
78049432896
-
Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice
-
Patrick DM, Montgomery RL, Qi X et al. Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. J. Clin. Invest. 120(11), 3912-3916 (2010
-
(2010)
J. Clin. Invest
, vol.120
, Issue.11
, pp. 3912-3916
-
-
Patrick, D.M.1
Montgomery, R.L.2
Qi, X.3
-
66
-
-
84855350458
-
Inhibition of miR-15 protects against cardiac ischemic injury
-
Hullinger TG, Montgomery RL, Seto AG et al. Inhibition of miR-15 protects against cardiac ischemic injury. Circ. Res. 110(1), 71-81 (2012
-
(2012)
Circ. Res
, vol.110
, Issue.1
, pp. 71-81
-
-
Hullinger, T.G.1
Montgomery, R.L.2
Seto, A.G.3
-
67
-
-
84893159810
-
Circulation research thematic synopsis: MicroRNAs
-
Editors T. Circulation research thematic synopsis: MicroRNAs. Circ. Res. 113(4), e30-e41 (2013
-
(2013)
Circ. Res
, vol.113
, Issue.4
-
-
Editors, T.1
-
68
-
-
55449100829
-
Toward microRNA-based therapeutics for heart disease: The sense in antisense
-
van Rooij E, Marshall WS, Olson EN. Toward microRNA-based therapeutics for heart disease: The sense in antisense. Circ. Res. 103(9), 919-928 (2008
-
(2008)
Circ. Res
, vol.103
, Issue.9
, pp. 919-928
-
-
Van Rooij, E.1
Marshall, W.S.2
Olson, E.N.3
-
70
-
-
84861891920
-
MicroRNA dysregulation in diabetic ischemic heart failure patients
-
Greco S, Fasanaro P, Castelvecchio S et al. MicroRNA dysregulation in diabetic ischemic heart failure patients. Diabetes 61(6), 1633-1641 (2012
-
(2012)
Diabetes
, vol.61
, Issue.6
, pp. 1633-1641
-
-
Greco, S.1
Fasanaro, P.2
Castelvecchio, S.3
-
71
-
-
34247589595
-
Control of stress-dependent cardiac growth and gene expression by a microRNA
-
van Rooij E, Sutherland LB, Qi X, Richardson JA, Hill J, Olson EN. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 316(5824), 575-579 (2007
-
(2007)
Science
, vol.316
, Issue.5824
, pp. 575-579
-
-
Van Rooij, E.1
Sutherland, L.B.2
Qi, X.3
Richardson, J.A.4
Hill, J.5
Olson, E.N.6
-
72
-
-
70349202176
-
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice
-
Callis TE, Pandya K, Seok HY et al. MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J. Clin. Invest. 119(9), 2772-2786 (2009
-
(2009)
J. Clin. Invest
, vol.119
, Issue.9
, pp. 2772-2786
-
-
Callis, T.E.1
Pandya, K.2
Seok, H.Y.3
-
73
-
-
79958841800
-
Mechanical modulation of cardiac microtubules
-
White E. Mechanical modulation of cardiac microtubules. Pflugers Arch. 462(1), 177-184 (2011
-
(2011)
Pflugers Arch
, vol.462
, Issue.1
, pp. 177-184
-
-
White, E.1
-
74
-
-
78649843756
-
MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-Amplification loop promoting calcineurin/NFAT signalling
-
da Costa Martins PA, Salic K, Gladka MM et al. MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-Amplification loop promoting calcineurin/NFAT signalling. Nat. Cell Biol. 12(12), 1220-1227 (2010
-
(2010)
Nat. Cell Biol
, vol.12
, Issue.12
, pp. 1220-1227
-
-
Da Costa Martins, P.A.1
Salic, K.2
Gladka, M.M.3
-
76
-
-
78149303249
-
MicroRNA sponges: Progress and possibilities
-
Ebert MS, Sharp PA. MicroRNA sponges: Progress and possibilities. RNA 16(11), 2043-2050 (2010
-
(2010)
RNA
, vol.16
, Issue.11
, pp. 2043-2050
-
-
Ebert, M.S.1
Sharp, P.A.2
-
77
-
-
84858783875
-
Extracellular/circulating microRNAs and their potential role in cardiovascular disease
-
Zhu H, Fan GC. Extracellular/circulating microRNAs and their potential role in cardiovascular disease. Am. J. Cardiovasc. Dis. 1(2), 138-149 (2011
-
(2011)
Am. J. Cardiovasc. Dis
, vol.1
, Issue.2
, pp. 138-149
-
-
Zhu, H.1
Fan, G.C.2
-
78
-
-
84874361869
-
Circulating cardio-enriched microRNAs are associated with long-Term prognosis following myocardial infarction
-
Gidlof O, Smith JG, Miyazu K et al. Circulating cardio-enriched microRNAs are associated with long-Term prognosis following myocardial infarction. BMC Cardiovasc. Disord. 13, 12 (2013
-
BMC Cardiovasc. Disord
, vol.13
, Issue.12
, pp. 2013
-
-
Gidlof, O.1
Smith, J.G.2
Miyazu, K.3
-
79
-
-
70449709345
-
Plasma miR-208 as a biomarker of myocardial injury
-
Ji X, Takahashi R, Hiura Y, Hirokawa G, Fukushima Y, Iwai N. Plasma miR-208 as a biomarker of myocardial injury. Clin. Chem. 55(11), 1944-1949 (2009
-
(2009)
Clin. Chem
, vol.55
, Issue.11
, pp. 1944-1949
-
-
Ji, X.1
Takahashi, R.2
Hiura, Y.3
Hirokawa, G.4
Fukushima, Y.5
Iwai, N.6
-
80
-
-
84880770209
-
Circulating p53-responsive microRNAs are predictive indicators of heart failure after acute myocardial infarction
-
Matsumoto S, Sakata Y, Nakatani D et al. Circulating p53-responsive microRNAs are predictive indicators of heart failure after acute myocardial infarction. Circ. Res. 13(3), 322-326 (2013
-
(2013)
Circ. Res
, vol.13
, Issue.3
, pp. 322-326
-
-
Matsumoto, S.1
Sakata, Y.2
Nakatani, D.3
-
81
-
-
80051605955
-
Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training
-
Pt16
-
Baggish AL, Hale A, Weiner RB et al. Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training. J. Physiol. 589(Pt 16), 3983-3994 (2011
-
(2011)
J. Physiol
, vol.589
, pp. 3983-3994
-
-
Baggish, A.L.1
Hale, A.2
Weiner, R.B.3
-
82
-
-
77649253288
-
MicroRNAs add a new dimension to cardiovascular disease
-
Small EM, Frost RJ, Olson EN. MicroRNAs add a new dimension to cardiovascular disease. Circulation 121(8), 1022-1032 (2010
-
(2010)
Circulation
, vol.121
, Issue.8
, pp. 1022-1032
-
-
Small, E.M.1
Frost, R.J.2
Olson, E.N.3
-
83
-
-
84860157611
-
Loss of the miR-144/451 cluster impairs ischaemic preconditioning- mediated cardioprotection by targeting Rac-1
-
Wang X, Zhu H, Zhang X et al. Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1. Cardiovasc. Res. 94(2), 379-390 (2012
-
(2012)
Cardiovasc. Res
, vol.94
, Issue.2
, pp. 379-390
-
-
Wang, X.1
Zhu, H.2
Zhang, X.3
-
84
-
-
77957225240
-
Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death
-
Zhang X, Wang X, Zhu H et al. Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death. J. Mol. Cell. Cardiol. 49(5), 841-850 (2010
-
(2010)
J. Mol. Cell. Cardiol
, vol.49
, Issue.5
, pp. 841-850
-
-
Zhang, X.1
Wang, X.2
Zhu, H.3
-
85
-
-
84866515571
-
MicroRNA-145 protects cardiomyocytes against hydrogen peroxide (H(2)O(2))-induced apoptosis through targeting the mitochondria apoptotic pathway
-
Li R, Yan G, Li Q et al. MicroRNA-145 protects cardiomyocytes against hydrogen peroxide (H(2)O(2))-induced apoptosis through targeting the mitochondria apoptotic pathway. PLoS ONE 7(9), e44907 (2012
-
(2012)
PLoS ONE
, vol.7
, Issue.9
-
-
Li, R.1
Yan, G.2
Li, Q.3
-
86
-
-
84859564908
-
MiR-221 promotes cardiac hypertrophy in vitro through the modulation of p27 expression
-
Wang C, Wang S, Zhao P et al. MiR-221 promotes cardiac hypertrophy in vitro through the modulation of p27 expression. J. Cell Biochem. 113(6), 2040-2046 (2012
-
(2012)
J. Cell Biochem
, vol.113
, Issue.6
, pp. 2040-2046
-
-
Wang, C.1
Wang, S.2
Zhao, P.3
-
87
-
-
84860623522
-
SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway
-
Kumarswamy R, Lyon AR, Volkmann I et al. SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway. Eur. Heart J. 33(9), 1067-1075 (2012
-
(2012)
Eur. Heart J.
, vol.33
, Issue.9
, pp. 1067-1075
-
-
Kumarswamy, R.1
Lyon, A.R.2
Volkmann, I.3
-
88
-
-
73449086958
-
Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions
-
Elia L, Contu R, Quintavalle M et al. Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions. Circulation 120(23), 2377-2385 (2009
-
(2009)
Circulation
, vol.120
, Issue.23
, pp. 2377-2385
-
-
Elia, L.1
Contu, R.2
Quintavalle, M.3
-
89
-
-
59849128881
-
MiR-133 and miR-30 regulate connective tissue growth factor: Implications for a role of microRNAs in myocardial matrix remodeling
-
176p following 178
-
Duisters RF, Tijsen AJ, Schroen B et al. miR-133 and miR-30 regulate connective tissue growth factor: Implications for a role of microRNAs in myocardial matrix remodeling. Circ. Res. 104(2), 170-178, 176p following 178 (2009
-
(2009)
Circ. Res
, vol.104
, Issue.2
, pp. 170-178
-
-
Duisters, R.F.1
Tijsen, A.J.2
Schroen, B.3
-
90
-
-
62349141343
-
MicroRNA expression in response to murine myocardial infarction: MiR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue
-
Roy S, Khanna S, Hussain SR et al. MicroRNA expression in response to murine myocardial infarction: MiR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue. Cardiovasc. Res. 82(1), 21-29 (2009
-
(2009)
Cardiovasc. Res
, vol.82
, Issue.1
, pp. 21-29
-
-
Roy, S.1
Khanna, S.2
Hussain, S.R.3
-
91
-
-
77957243894
-
MicroRNA-210 as a novel therapy for treatment of ischemic heart disease
-
Suppl. S124-S131
-
Hu S, Huang M, Li Z et al. MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. Circulation 122(11 Suppl.), S124-S131 (2010
-
Circulation
, vol.122
, Issue.11
, pp. 2010
-
-
Hu, S.1
Huang, M.2
Li, Z.3
-
92
-
-
84857791711
-
Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice
-
Wang J, Song Y, Zhang Y et al. Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice. Cell. Res. 22(3), 516-527 (2012
-
(2012)
Cell. Res
, vol.22
, Issue.3
, pp. 516-527
-
-
Wang, J.1
Song, Y.2
Zhang, Y.3
-
93
-
-
77954766181
-
Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischaemia-reperfusion injury
-
Ye Y, Hu Z, Lin Y, Zhang C, Perez-Polo JR. Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischaemia-reperfusion injury. Cardiovasc. Res. 87(3), 535-544 (2010
-
(2010)
Cardiovasc. Res
, vol.87
, Issue.3
, pp. 535-544
-
-
Ye, Y.1
Hu, Z.2
Lin, Y.3
Zhang, C.4
Perez-Polo, J.R.5
|