Exploring the determinants of trace amine-associated receptor 1's functional selectivity for the stereoisomers of amphetamine and methamphetamine

Journal of Medicinal Chemistry

Volumn 57, Issue 2, 2014, Pages 378-390

  Reese, Edmund A ^a   Norimatsu, Yohei ^b   Grandy, Madeline S ^a   Suchland, Katherine L ^a   Bunzow, James R ^a   Grandy, David K ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b A T STILL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; AMPHETAMINE; DOPAMINE; G PROTEIN COUPLED RECEPTOR; METHAMPHETAMINE; PHENETHYLAMINE; TRACE AMINE ASSOCIATED RECEPTOR 1; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOMER; MOLECULAR DYNAMICS; MOUSE; MUTANT; NONHUMAN; PROTEIN INTERACTION; SIMULATION; STEREOCHEMISTRY; STEREOISOMERISM;

AMINO ACID SEQUENCE; AMPHETAMINE; ANIMALS; BINDING SITES; CENTRAL NERVOUS SYSTEM STIMULANTS; CYCLIC AMP; HEK293 CELLS; HUMANS; METHAMPHETAMINE; MICE; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; RATS; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE HOMOLOGY, AMINO ACID; STEREOISOMERISM;

EID: 84893132298     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401316v     Document Type: Article

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