메뉴 건너뛰기




Volumn 11, Issue 1, 2014, Pages 153-160

Treatment of Huntington's Disease

Author keywords

CAG repeat disorders; Chorea; Huntington's disease; Movement disorders; Subcortical dementia; Tetrabenazine

Indexed keywords

4 AMINOBUTYRIC ACID; ARIPIPRAZOLE; DOPAMINE; GLUTAMIC ACID; NEUROTRANSMITTER; OLANZAPINE; TETRABENAZINE;

EID: 84893118401     PISSN: 19337213     EISSN: 18787479     Source Type: Journal    
DOI: 10.1007/s13311-013-0244-z     Document Type: Review
Times cited : (174)

References (112)
  • 1
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Disease Collaborative Research Group
    • The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993;72: 971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 2
    • 0035937523 scopus 로고    scopus 로고
    • Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
    • Nucifora FC Jr, Sasaki M, Peters MF, et al. Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science 2001;291: 2423-2428.
    • (2001) Science , vol.291 , pp. 2423-2428
    • Nucifora Jr., F.C.1    Sasaki, M.2    Peters, M.F.3
  • 3
    • 66749167799 scopus 로고    scopus 로고
    • Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity
    • Subramaniam S, Sixt KM, Barrow R, Snyder SH. Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity. Science 2009;324: 1327-1330.
    • (2009) Science , vol.324 , pp. 1327-1330
    • Subramaniam, S.1    Sixt, K.M.2    Barrow, R.3    Snyder, S.H.4
  • 4
    • 74849091009 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease
    • Ribeiro FM, Paquet M, Ferreira LT, et al. Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease. J Neurosci 2010;30: 316-324.
    • (2010) J Neurosci , vol.30 , pp. 316-324
    • Ribeiro, F.M.1    Paquet, M.2    Ferreira, L.T.3
  • 5
    • 33947604998 scopus 로고    scopus 로고
    • Complex movement behavior and progression of Huntington's disease
    • Andrich J, Saft C, Ostholt N, Müller T. Complex movement behavior and progression of Huntington's disease. Neurosci Lett 2007;416: 272-274.
    • (2007) Neurosci Lett , vol.416 , pp. 272-274
    • Andrich, J.1    Saft, C.2    Ostholt, N.3    Müller, T.4
  • 6
    • 33646686133 scopus 로고    scopus 로고
    • Functional decline due to chorea in Huntington's disease
    • Frank S, Marshall F, Plumb S, et al. Functional decline due to chorea in Huntington's disease. Neurology 2004;62(Suppl. 5): A204.
    • (2004) Neurology , vol.62 , Issue.SUPPL. 5
    • Frank, S.1    Marshall, F.2    Plumb, S.3
  • 7
    • 0037056392 scopus 로고    scopus 로고
    • Huntington's disease: a randomized, controlled trial using the NMDA-antagonist amantadine
    • Verhagen ML, Morris MJ, Farmer C, et al. Huntington's disease: a randomized, controlled trial using the NMDA-antagonist amantadine. Neurology 2002;59: 694-699.
    • (2002) Neurology , vol.59 , pp. 694-699
    • Verhagen, M.L.1    Morris, M.J.2    Farmer, C.3
  • 8
    • 0038701684 scopus 로고    scopus 로고
    • Huntingtin aggregation and toxicity in Huntington's disease
    • Bates G. Huntingtin aggregation and toxicity in Huntington's disease. Lancet 2003;361: 1642-1644.
    • (2003) Lancet , vol.361 , pp. 1642-1644
    • Bates, G.1
  • 9
    • 7244236320 scopus 로고    scopus 로고
    • Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
    • Arrasate M, Mitra S, Schweitzer ES, Segal MR, Finkbeiner S. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 2004;431: 805-810.
    • (2004) Nature , vol.431 , pp. 805-810
    • Arrasate, M.1    Mitra, S.2    Schweitzer, E.S.3    Segal, M.R.4    Finkbeiner, S.5
  • 10
    • 0034081681 scopus 로고    scopus 로고
    • The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease
    • Glass M, Dragunow M, Faull RL. The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease. Neuroscience 2000;97: 505-519.
    • (2000) Neuroscience , vol.97 , pp. 505-519
    • Glass, M.1    Dragunow, M.2    Faull, R.L.3
  • 11
    • 0026717486 scopus 로고
    • Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease
    • Albin RL, Reiner A, Anderson KD, et al. Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease. Ann Neurol 1992;31: 425-430.
    • (1992) Ann Neurol , vol.31 , pp. 425-430
    • Albin, R.L.1    Reiner, A.2    Anderson, K.D.3
  • 13
    • 0032860432 scopus 로고    scopus 로고
    • The selective vulnerability of striatopallidal neurons
    • Mitchell IJ, Cooper AJ, Griffiths MR. The selective vulnerability of striatopallidal neurons. Prog Neurobiol 1999;59: 691-719.
    • (1999) Prog Neurobiol , vol.59 , pp. 691-719
    • Mitchell, I.J.1    Cooper, A.J.2    Griffiths, M.R.3
  • 14
    • 12644252940 scopus 로고    scopus 로고
    • Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease
    • Antonini A, Leenders KL, Spiegel R, et al. Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease. Brain 1996;119: 2085-2095.
    • (1996) Brain , vol.119 , pp. 2085-2095
    • Antonini, A.1    Leenders, K.L.2    Spiegel, R.3
  • 15
    • 0030612119 scopus 로고    scopus 로고
    • Dopamine D1 and D2 receptor gene expression in the striatum in Huntington's disease
    • Augood SJ, Faull RL, Emson PC. Dopamine D1 and D2 receptor gene expression in the striatum in Huntington's disease. Ann Neurol 1997;42: 215-221.
    • (1997) Ann Neurol , vol.42 , pp. 215-221
    • Augood, S.J.1    Faull, R.L.2    Emson, P.C.3
  • 16
    • 35648963039 scopus 로고    scopus 로고
    • Thalamic metabolism and symptom onset in preclinical Huntington's disease
    • Feigin A, Tang C, Ma Y, et al. Thalamic metabolism and symptom onset in preclinical Huntington's disease. Brain 2007;130: 2858-2867.
    • (2007) Brain , vol.130 , pp. 2858-2867
    • Feigin, A.1    Tang, C.2    Ma, Y.3
  • 18
    • 0029895292 scopus 로고    scopus 로고
    • Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease
    • Weeks RA, Piccini P, Harding AE, et al. Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease. Ann Neurol 1996;40: 49-54.
    • (1996) Ann Neurol , vol.40 , pp. 49-54
    • Weeks, R.A.1    Piccini, P.2    Harding, A.E.3
  • 19
    • 0032568517 scopus 로고    scopus 로고
    • Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene
    • Cha JH, Kosinski CM, Kerner JA, et al. Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene. Proc Natl Acad Sci U S A 1998;95: 6480-6485.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 6480-6485
    • Cha, J.H.1    Kosinski, C.M.2    Kerner, J.A.3
  • 20
    • 0015790444 scopus 로고
    • Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain
    • Perry TL, Hansen S, Kloster M. Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain. N Engl J Med 1973;288: 337-342.
    • (1973) N Engl J Med , vol.288 , pp. 337-342
    • Perry, T.L.1    Hansen, S.2    Kloster, M.3
  • 21
    • 62149136286 scopus 로고    scopus 로고
    • Functional imaging in Huntington's disease
    • Paulsen JS. Functional imaging in Huntington's disease. Exp Neurol 2009;216: 272-277.
    • (2009) Exp Neurol , vol.216 , pp. 272-277
    • Paulsen, J.S.1
  • 22
    • 0141432169 scopus 로고    scopus 로고
    • Changes in GAD67 mRNA expression evidenced by in situ hybridization in the brain of R6/2 transgenic mice
    • Gourfinkel-An I, Parain K, Hartmann A, et al. Changes in GAD67 mRNA expression evidenced by in situ hybridization in the brain of R6/2 transgenic mice. J Neurochem 2003;86: 1369-1378.
    • (2003) J Neurochem , vol.86 , pp. 1369-1378
    • Gourfinkel-An, I.1    Parain, K.2    Hartmann, A.3
  • 23
    • 0035180327 scopus 로고    scopus 로고
    • Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice
    • Nicniocaill B, Haraldsson B, Hansson O, et al. Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice. Eur J Neurosci 2001;13: 206-210.
    • (2001) Eur J Neurosci , vol.13 , pp. 206-210
    • Nicniocaill, B.1    Haraldsson, B.2    Hansson, O.3
  • 24
    • 1242338856 scopus 로고    scopus 로고
    • Huntingtin-protein interactions and the pathogenesis of Huntington's disease
    • Li SH, Li XJ. Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends Genet 2004;20: 146-154.
    • (2004) Trends Genet , vol.20 , pp. 146-154
    • Li, S.H.1    Li, X.J.2
  • 25
    • 0035947372 scopus 로고    scopus 로고
    • Impairment of the ubiquitin-proteasome system by protein aggregation
    • Bence NF, Sampat RM, Kopito RR. Impairment of the ubiquitin-proteasome system by protein aggregation. Science 2001;292: 1552-1555.
    • (2001) Science , vol.292 , pp. 1552-1555
    • Bence, N.F.1    Sampat, R.M.2    Kopito, R.R.3
  • 26
    • 0036566266 scopus 로고    scopus 로고
    • Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
    • Ravikumar B, Duden R, Rubinsztein DC. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum Mol Genet 2002;11: 1107-1117.
    • (2002) Hum Mol Genet , vol.11 , pp. 1107-1117
    • Ravikumar, B.1    Duden, R.2    Rubinsztein, D.C.3
  • 27
    • 0034283877 scopus 로고    scopus 로고
    • Transcriptional dysregulation in Huntington's disease
    • Cha JH. Transcriptional dysregulation in Huntington's disease. Trends Neurosci 2000;23: 387-392.
    • (2000) Trends Neurosci , vol.23 , pp. 387-392
    • Cha, J.H.1
  • 28
    • 0037322570 scopus 로고    scopus 로고
    • Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease
    • Cepeda C, Hurst RS, Calvert CR, et al. Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease. J Neurosci 2003;23: 961-969.
    • (2003) J Neurosci , vol.23 , pp. 961-969
    • Cepeda, C.1    Hurst, R.S.2    Calvert, C.R.3
  • 29
    • 0026357457 scopus 로고
    • 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin
    • Ludolph AC, He F, Spencer PS, Hammerstad J, Sabri M. 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin. Can J Neurol Sci 1991;18: 492-498.
    • (1991) Can J Neurol Sci , vol.18 , pp. 492-498
    • Ludolph, A.C.1    He, F.2    Spencer, P.S.3    Hammerstad, J.4    Sabri, M.5
  • 30
    • 12144280807 scopus 로고    scopus 로고
    • Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways
    • Gunawardena S, Goldstein LS. Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways. Arch Neurol 2005;62: 46-51.
    • (2005) Arch Neurol , vol.62 , pp. 46-51
    • Gunawardena, S.1    Goldstein, L.S.2
  • 31
    • 0026684333 scopus 로고
    • The epidemiology of Huntington's disease
    • Harper PS. The epidemiology of Huntington's disease. Hum Genet 1992;89: 365-376.
    • (1992) Hum Genet , vol.89 , pp. 365-376
    • Harper, P.S.1
  • 32
    • 0029098272 scopus 로고
    • The epidemiology of Huntington's disease in Northern Ireland
    • Morrison PJ, Johnston WP, Nevin NC. The epidemiology of Huntington's disease in Northern Ireland. J Med Genet 1995;32: 524-530.
    • (1995) J Med Genet , vol.32 , pp. 524-530
    • Morrison, P.J.1    Johnston, W.P.2    Nevin, N.C.3
  • 33
    • 65649125624 scopus 로고    scopus 로고
    • Epidemiology of Huntington's disease in Slovenia
    • Peterlin B, Kobal J, Teran N, et al. Epidemiology of Huntington's disease in Slovenia. Acta Neurol Scand 2009;119: 371-375.
    • (2009) Acta Neurol Scand , vol.119 , pp. 371-375
    • Peterlin, B.1    Kobal, J.2    Teran, N.3
  • 34
    • 70450159037 scopus 로고    scopus 로고
    • Clinical and genetic characteristics of Mexican Huntington's disease patients
    • Alonso ME, Ochoa A, Boll MC, et al. Clinical and genetic characteristics of Mexican Huntington's disease patients. Mov Disord 2009;24: 2012-2015.
    • (2009) Mov Disord , vol.24 , pp. 2012-2015
    • Alonso, M.E.1    Ochoa, A.2    Boll, M.C.3
  • 35
    • 0024892247 scopus 로고
    • The prevalence and patterns of care of Huntington's chorea in Grampian
    • Simpson SA, Johnston AW. The prevalence and patterns of care of Huntington's chorea in Grampian. Br J Psychiatry 1989;155: 799-804.
    • (1989) Br J Psychiatry , vol.155 , pp. 799-804
    • Simpson, S.A.1    Johnston, A.W.2
  • 36
    • 0025290717 scopus 로고
    • Huntington's disease in Venezuela: 7 years of follow-up on symptomatic and asymptomatic individuals
    • Penney JB Jr, Young AB, Shoulson I, et al. Huntington's disease in Venezuela: 7 years of follow-up on symptomatic and asymptomatic individuals. Mov Disord 1990;5: 93-99.
    • (1990) Mov Disord , vol.5 , pp. 93-99
    • Penney Jr., J.B.1    Young, A.B.2    Shoulson, I.3
  • 37
    • 13944253854 scopus 로고    scopus 로고
    • The epidemiology of Huntington's disease
    • In: Bates G, Harper P, Jones L, eds, 3rd ed. Oxford Monographs on Medical Genetics
    • Harper PS. The epidemiology of Huntington's disease. In: Bates G, Harper P, Jones L, eds. Huntington's disease. 3rd ed. Oxford Monographs on Medical Genetics, 2002.
    • (2002) Huntington's disease
    • Harper, P.S.1
  • 38
    • 34250327141 scopus 로고    scopus 로고
    • Psychiatric and cognitive difficulties as indicators of juvenile huntington disease onset in 29 patients
    • Ribai P, Nguyen K, Hahn-Barma V, et al. Psychiatric and cognitive difficulties as indicators of juvenile huntington disease onset in 29 patients. Arch Neurol 2007;64: 813-819.
    • (2007) Arch Neurol , vol.64 , pp. 813-819
    • Ribai, P.1    Nguyen, K.2    Hahn-Barma, V.3
  • 40
    • 84893040554 scopus 로고    scopus 로고
    • Lulu Press, US
    • Pollard J. Hurry up and wait: a cognitive care companion. 9/25/08. XX, Lulu Press, US, 2008. http://www. lulu. com/shop/james-pollard/hurry-up-and-wait/paperback/product-3610588. html#productDetails.
    • (2008) Hurry up and wait: A cognitive care companion
    • Pollard, J.1
  • 41
    • 33749861388 scopus 로고    scopus 로고
    • Effect of donepezil on motor and cognitive function in Huntington disease
    • Cubo E, Shannon KM, Tracy D, et al. Effect of donepezil on motor and cognitive function in Huntington disease. Neurology 2006;67: 1268-1271.
    • (2006) Neurology , vol.67 , pp. 1268-1271
    • Cubo, E.1    Shannon, K.M.2    Tracy, D.3
  • 43
    • 70349655241 scopus 로고    scopus 로고
    • Randomized controlled trial of atomoxetine for cognitive dysfunction in early Huntington disease
    • Beglinger LJ, Adams WH, Paulson H, et al. Randomized controlled trial of atomoxetine for cognitive dysfunction in early Huntington disease. J Clin Psychopharmacol 2009;29: 484-487.
    • (2009) J Clin Psychopharmacol , vol.29 , pp. 484-487
    • Beglinger, L.J.1    Adams, W.H.2    Paulson, H.3
  • 44
    • 81055156193 scopus 로고    scopus 로고
    • Paulsen Cognitive impairment in Huntington disease: diagnosis and treatment
    • Paulsen Cognitive impairment in Huntington disease: diagnosis and treatment. Curr Neurol Neurosci Rep 2011;11: 474-483.
    • (2011) Curr Neurol Neurosci Rep , vol.11 , pp. 474-483
  • 45
    • 84876280381 scopus 로고    scopus 로고
    • The pathophysiology and pharmacological treatment of Huntington disease
    • Pidgeon C, Rickards H. The pathophysiology and pharmacological treatment of Huntington disease. Behav Neurol 2013;26: 245-253.
    • (2013) Behav Neurol , vol.26 , pp. 245-253
    • Pidgeon, C.1    Rickards, H.2
  • 47
    • 36048940046 scopus 로고    scopus 로고
    • Tetrabenazine in the treatment of Huntington's Disease
    • Paleacu D. Tetrabenazine in the treatment of Huntington's Disease. Neuropsychiatr Dis Treat 2007;3: 545-551.
    • (2007) Neuropsychiatr Dis Treat , vol.3 , pp. 545-551
    • Paleacu, D.1
  • 48
    • 0020510988 scopus 로고
    • Differential interactions of phencyclidine with tetrabenazine and reserpine affecting intraneuronal dopamine
    • Bagchi SP. Differential interactions of phencyclidine with tetrabenazine and reserpine affecting intraneuronal dopamine. Biochem Pharmacol 1983;32: 2851-2856.
    • (1983) Biochem Pharmacol , vol.32 , pp. 2851-2856
    • Bagchi, S.P.1
  • 49
    • 41249096422 scopus 로고    scopus 로고
    • Symptomatic treatment of Huntington disease
    • Adam OR, Jankovic J. Symptomatic treatment of Huntington disease. Neurotherapeutics 2008;5: 181-197.
    • (2008) Neurotherapeutics , vol.5 , pp. 181-197
    • Adam, O.R.1    Jankovic, J.2
  • 50
    • 53049084348 scopus 로고    scopus 로고
    • The current clinical management of Huntington's disease
    • Phillips W, Shannon KM, Barker RA. The current clinical management of Huntington's disease. Mov Disord 2008;23: 1491-1504.
    • (2008) Mov Disord , vol.23 , pp. 1491-1504
    • Phillips, W.1    Shannon, K.M.2    Barker, R.A.3
  • 51
    • 52049085768 scopus 로고    scopus 로고
    • Pathophysiology of Huntington's disease: from huntingtin functions to potential treatments
    • Roze E, Saudou F, Caboche J. Pathophysiology of Huntington's disease: from huntingtin functions to potential treatments. Curr Opin Neurol 2008;21: 497-503.
    • (2008) Curr Opin Neurol , vol.21 , pp. 497-503
    • Roze, E.1    Saudou, F.2    Caboche, J.3
  • 52
    • 44449131447 scopus 로고    scopus 로고
    • Huntington's disease: from pathology and genetics to potential therapies
    • Imarisio S, Carmichael J, Korolchuk V, et al. Huntington's disease: from pathology and genetics to potential therapies. Biochem J 2008;412: 191-209.
    • (2008) Biochem J , vol.412 , pp. 191-209
    • Imarisio, S.1    Carmichael, J.2    Korolchuk, V.3
  • 53
    • 33846225133 scopus 로고    scopus 로고
    • Huntington's disease
    • Walker FO. Huntington's disease. Lancet 2007;369: 218-228.
    • (2007) Lancet , vol.369 , pp. 218-228
    • Walker, F.O.1
  • 54
    • 68249146267 scopus 로고    scopus 로고
    • Treatment of hyperkinetic movement disorders
    • Jankovic J. Treatment of hyperkinetic movement disorders. Lancet Neurol 2009;8: 844-856.
    • (2009) Lancet Neurol , vol.8 , pp. 844-856
    • Jankovic, J.1
  • 55
    • 33745759912 scopus 로고    scopus 로고
    • Pharmacological management of Huntington's disease: an evidence-based review
    • Bonelli RM, Wenning GK. Pharmacological management of Huntington's disease: an evidence-based review. Curr Pharm Des 2006;12: 2701-2720.
    • (2006) Curr Pharm Des , vol.12 , pp. 2701-2720
    • Bonelli, R.M.1    Wenning, G.K.2
  • 57
    • 34147207888 scopus 로고    scopus 로고
    • Huntington's disease: clinical characteristics, pathogenesis and therapies
    • Nakamura K, Aminoff MJ. Huntington's disease: clinical characteristics, pathogenesis and therapies. Drugs Today (Barc) 2007;43: 97-116.
    • (2007) Drugs Today (Barc) , vol.43 , pp. 97-116
    • Nakamura, K.1    Aminoff, M.J.2
  • 58
    • 30344476118 scopus 로고    scopus 로고
    • Pharmaceutical, cellular and genetic therapies for Huntington's disease
    • Handley OJ, Naji JJ, Dunnett SB, Rosser AE. Pharmaceutical, cellular and genetic therapies for Huntington's disease. Clin Sci (Lond) 2006;110: 73-88.
    • (2006) Clin Sci (Lond) , vol.110 , pp. 73-88
    • Handley, O.J.1    Naji, J.J.2    Dunnett, S.B.3    Rosser, A.E.4
  • 59
    • 1842854595 scopus 로고    scopus 로고
    • A review of the treatment options for Huntington's disease
    • Bonelli RM, Hofmann P. A review of the treatment options for Huntington's disease. Expert Opin Pharmacother 2004;5: 767-776.
    • (2004) Expert Opin Pharmacother , vol.5 , pp. 767-776
    • Bonelli, R.M.1    Hofmann, P.2
  • 61
    • 77949988313 scopus 로고    scopus 로고
    • Advances in the pharmacological management of Huntington's Disease
    • Frank SA, Jankovic J. Advances in the pharmacological management of Huntington's Disease. Drugs 2010;70: 561-571.
    • (2010) Drugs , vol.70 , pp. 561-571
    • Frank, S.A.1    Jankovic, J.2
  • 62
    • 80054893761 scopus 로고    scopus 로고
    • Tetrabenazine for the treatment of chorea and other hyperkinetic movement disorders
    • Jankovic J, Clarence-Smith K. Tetrabenazine for the treatment of chorea and other hyperkinetic movement disorders. Expert Rev Neurother 2011;11: 1509-1523.
    • (2011) Expert Rev Neurother , vol.11 , pp. 1509-1523
    • Jankovic, J.1    Clarence-Smith, K.2
  • 63
    • 0021251068 scopus 로고
    • Tetrabenazine-induced depletion of brain monoamines: mechanism by which desmethylimipramine protects cortical norepinephrine
    • Pettibone DJ, Pflueger AB, Totaro JA. Tetrabenazine-induced depletion of brain monoamines: mechanism by which desmethylimipramine protects cortical norepinephrine. Eur J Pharmacol 1984;102: 431-436.
    • (1984) Eur J Pharmacol , vol.102 , pp. 431-436
    • Pettibone, D.J.1    Pflueger, A.B.2    Totaro, J.A.3
  • 64
    • 0023236626 scopus 로고
    • Concentration-effect relationships of tetrabenazine and dihydrotetrabenazine in the rat
    • Mehvar R, Jamali F. Concentration-effect relationships of tetrabenazine and dihydrotetrabenazine in the rat. J Pharm Sci 1987;76: 461-465.
    • (1987) J Pharm Sci , vol.76 , pp. 461-465
    • Mehvar, R.1    Jamali, F.2
  • 65
    • 0029056219 scopus 로고
    • Regional distribution of monoamine vesicular uptake sites in the mesencephalon of control subjects and patients with Parkinson's disease: a postmortem study using tritiated tetrabenazine
    • Thibaut F, Faucheux BA, Marquez J, et al. Regional distribution of monoamine vesicular uptake sites in the mesencephalon of control subjects and patients with Parkinson's disease: a postmortem study using tritiated tetrabenazine. Brain Res 1995;692: 233-243.
    • (1995) Brain Res , vol.692 , pp. 233-243
    • Thibaut, F.1    Faucheux, B.A.2    Marquez, J.3
  • 66
    • 33847694844 scopus 로고    scopus 로고
    • Short-term effects of tetrabenazine on chorea associated with Huntington's disease
    • Kenney C, Hunter C, Davidson A, Jankovic J. Short-term effects of tetrabenazine on chorea associated with Huntington's disease. Mov Disord 2007;22: 10-13.
    • (2007) Mov Disord , vol.22 , pp. 10-13
    • Kenney, C.1    Hunter, C.2    Davidson, A.3    Jankovic, J.4
  • 67
    • 0021288772 scopus 로고
    • Reserpine binding to bovine chromaffin granule membranes. Characterization and comparison with dihydrotetrabenazine binding
    • Scherman D, Henry JP. Reserpine binding to bovine chromaffin granule membranes. Characterization and comparison with dihydrotetrabenazine binding. Mol Pharmacol 1984;25: 113-122.
    • (1984) Mol Pharmacol , vol.25 , pp. 113-122
    • Scherman, D.1    Henry, J.P.2
  • 68
    • 33645798913 scopus 로고    scopus 로고
    • Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial
    • Huntington Study Group
    • Huntington Study Group. Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial. Neurology 2006;66: 366-372.
    • (2006) Neurology , vol.66 , pp. 366-372
  • 69
    • 0031029072 scopus 로고    scopus 로고
    • Long-term effects of tetrabenazine in hyperkinetic movement disorders
    • Jankovic J, Beach J. Long-term effects of tetrabenazine in hyperkinetic movement disorders. Neurology 1997;48: 358-362.
    • (1997) Neurology , vol.48 , pp. 358-362
    • Jankovic, J.1    Beach, J.2
  • 70
    • 33847731495 scopus 로고    scopus 로고
    • Long-term tolerability of tetrabenazine in the treatment of hyperkinetic movement disorders
    • Kenney C, Hunter C, Jankovic J. Long-term tolerability of tetrabenazine in the treatment of hyperkinetic movement disorders. Mov Disord 2007;22: 193-197.
    • (2007) Mov Disord , vol.22 , pp. 193-197
    • Kenney, C.1    Hunter, C.2    Jankovic, J.3
  • 71
    • 59849086625 scopus 로고    scopus 로고
    • The long-term effect of tetrabenazine in the management of Huntington disease
    • Fasano A, Cadeddu F, Guidubaldi A, et al. The long-term effect of tetrabenazine in the management of Huntington disease. Clin Neuropharmacol 2008;31: 313-318.
    • (2008) Clin Neuropharmacol , vol.31 , pp. 313-318
    • Fasano, A.1    Cadeddu, F.2    Guidubaldi, A.3
  • 72
    • 74549128476 scopus 로고    scopus 로고
    • Tetrabenazine as anti-chorea therapy in Huntington disease: an open-label continuation study
    • Frank S. Tetrabenazine as anti-chorea therapy in Huntington disease: an open-label continuation study. Huntington Study Group/TETRA-HD Investigators. BMC Neurol 2009;9: 62.
    • (2009) Huntington Study Group/TETRA-HD Investigators. BMC Neurol , vol.9 , pp. 62
    • Frank, S.1
  • 73
    • 84860303319 scopus 로고    scopus 로고
    • Xenazine
    • Xenazine. Product information, September 2012. http://www. lundbeck. com/upload/us/files/pdf/Products/Xenazine_PI_US_EN. pdf.
    • (2012) Product information
  • 75
    • 0021175970 scopus 로고
    • A double blind trial of sulpiride in Huntington's disease and tardive dyskinesia
    • Quinn N, Marsden CD. A double blind trial of sulpiride in Huntington's disease and tardive dyskinesia. J Neurol Neurosurg Psychiatry 1984;47: 844-847.
    • (1984) J Neurol Neurosurg Psychiatry , vol.47 , pp. 844-847
    • Quinn, N.1    Marsden, C.D.2
  • 76
    • 0021733679 scopus 로고
    • Tiapride versus placebo: a double-blind comparative study in the management of Huntington's chorea
    • Deroover J, Baro F, Bourguignon RP, Smets P. Tiapride versus placebo: a double-blind comparative study in the management of Huntington's chorea. Curr Med Res Opin 1984;9: 329-338.
    • (1984) Curr Med Res Opin , vol.9 , pp. 329-338
    • Deroover, J.1    Baro, F.2    Bourguignon, R.P.3    Smets, P.4
  • 78
    • 0023868584 scopus 로고
    • Serum haloperidol concentration and choreiform movements in Huntington's disease
    • Barr AN, Fischer JH, Koller WC, Spunt AL, Singhal A. Serum haloperidol concentration and choreiform movements in Huntington's disease. Neurology 1988;38: 84-88.
    • (1988) Neurology , vol.38 , pp. 84-88
    • Barr, A.N.1    Fischer, J.H.2    Koller, W.C.3    Spunt, A.L.4    Singhal, A.5
  • 83
    • 0033000665 scopus 로고    scopus 로고
    • The use of olanzapine for movement disorder in Huntington's disease: a first case report
    • Dipple HC. The use of olanzapine for movement disorder in Huntington's disease: a first case report. J Neurol Neurosurg Psychiatry 1999;67: 123-124.
    • (1999) J Neurol Neurosurg Psychiatry , vol.67 , pp. 123-124
    • Dipple, H.C.1
  • 84
    • 33746687898 scopus 로고    scopus 로고
    • Clinical experience with risperidone and memantine in the treatment of Huntington's disease
    • Cankurtaran ES, Ozalp E, Soygur H, Cakir A. Clinical experience with risperidone and memantine in the treatment of Huntington's disease. J Natl Med Assoc. 2006;98: 1353-1355.
    • (2006) J Natl Med Assoc. , vol.98 , pp. 1353-1355
    • Cankurtaran, E.S.1    Ozalp, E.2    Soygur, H.3    Cakir, A.4
  • 85
    • 0036038875 scopus 로고    scopus 로고
    • Risperidone in chorea and psychosis of Huntington's disease
    • Erdemoglu AK, Boratav C. Risperidone in chorea and psychosis of Huntington's disease. Eur J Neurol 2002;9: 182-183.
    • (2002) Eur J Neurol , vol.9 , pp. 182-183
    • Erdemoglu, A.K.1    Boratav, C.2
  • 86
    • 0031708158 scopus 로고    scopus 로고
    • Use of risperidone in psychosis associated with Huntington's disease
    • Madhusoodanan S, Brenner R. Use of risperidone in psychosis associated with Huntington's disease. Am J Geriatr Psychiatry 1998;6: 347-349.
    • (1998) Am J Geriatr Psychiatry , vol.6 , pp. 347-349
    • Madhusoodanan, S.1    Brenner, R.2
  • 88
    • 29544445190 scopus 로고    scopus 로고
    • Quetiapine in the treatment of behavioral disturbances in patients with Huntington's disease
    • Alpay M, Koroshetz WJ. Quetiapine in the treatment of behavioral disturbances in patients with Huntington's disease. Psychosomatics 2006;47: 70-72.
    • (2006) Psychosomatics , vol.47 , pp. 70-72
    • Alpay, M.1    Koroshetz, W.J.2
  • 89
    • 3042733763 scopus 로고    scopus 로고
    • Quetiapine in the management of psychosis secondary to Huntington's disease: a case report
    • Seitz DP, Millson RC. Quetiapine in the management of psychosis secondary to Huntington's disease: a case report. Can J Psychiatry 2004;49: 413.
    • (2004) Can J Psychiatry , vol.49 , pp. 413
    • Seitz, D.P.1    Millson, R.C.2
  • 90
    • 0036041559 scopus 로고    scopus 로고
    • Quetiapine in Huntington's disease: a first case report
    • Bonelli RM, Niederwieser G. Quetiapine in Huntington's disease: a first case report. J Neurol 2002;249: 1114-1115.
    • (2002) J Neurol , vol.249 , pp. 1114-1115
    • Bonelli, R.M.1    Niederwieser, G.2
  • 92
    • 70449710919 scopus 로고    scopus 로고
    • Aripiprazole in the treatment of Huntington's disease: a case series
    • Ciammola A, Sassone J, Colciago C, et al. Aripiprazole in the treatment of Huntington's disease: a case series. Neuropsychiatr Dis Treat 2009;5: 1-4.
    • (2009) Neuropsychiatr Dis Treat , vol.5 , pp. 1-4
    • Ciammola, A.1    Sassone, J.2    Colciago, C.3
  • 93
    • 61449249292 scopus 로고    scopus 로고
    • Treatment of the symptoms of Huntington's disease: preliminary results comparing aripiprazole and tetrabenazine
    • Brusa L, Orlacchio A, Moschella V, Iani C, Bernardi G, Mercuri NB. Treatment of the symptoms of Huntington's disease: preliminary results comparing aripiprazole and tetrabenazine. Mov Disord 2009;24: 126-129.
    • (2009) Mov Disord , vol.24 , pp. 126-129
    • Brusa, L.1    Orlacchio, A.2    Moschella, V.3    Iani, C.4    Bernardi, G.5    Mercuri, N.B.6
  • 94
    • 51349084524 scopus 로고    scopus 로고
    • Aripiprazole effects on psychosis and chorea in a patient with Huntington's disease
    • Lin WC, Chou YH. Aripiprazole effects on psychosis and chorea in a patient with Huntington's disease. Am J Psychiatry 2008;165: 1207-1208.
    • (2008) Am J Psychiatry , vol.165 , pp. 1207-1208
    • Lin, W.C.1    Chou, Y.H.2
  • 95
    • 0036757043 scopus 로고    scopus 로고
    • Amantadine in Huntington's disease: open-label video-blinded study
    • Lucetti C, Gambaccini G, Bernardini S, et al. Amantadine in Huntington's disease: open-label video-blinded study. Neurol Sci 2002;23(Suppl. 2): S83-S84.
    • (2002) Neurol Sci , vol.23 , Issue.SUPPL. 2
    • Lucetti, C.1    Gambaccini, G.2    Bernardini, S.3
  • 96
    • 0023231127 scopus 로고
    • Adverse behavioral effects of amantadine therapy in Huntington's disease
    • Stewart JT. Adverse behavioral effects of amantadine therapy in Huntington's disease. South Med J 1987;80: 1324-1325.
    • (1987) South Med J , vol.80 , pp. 1324-1325
    • Stewart, J.T.1
  • 97
    • 0345600893 scopus 로고    scopus 로고
    • Dosage effects of riluzole in Huntington's disease: a multicenter placebo-controlled study
    • Huntington Study Group
    • Huntington Study Group. Dosage effects of riluzole in Huntington's disease: a multicenter placebo-controlled study. Neurology 2003;61: 1551-1556.
    • (2003) Neurology , vol.61 , pp. 1551-1556
  • 98
    • 34948838383 scopus 로고    scopus 로고
    • Riluzole in Huntington's disease: a 3-year, randomized controlled study
    • Landwehrmeyer GB, Dubois B, de Yebenes JG, et al. Riluzole in Huntington's disease: a 3-year, randomized controlled study. Ann Neurol 2007;62: 262-272.
    • (2007) Ann Neurol , vol.62 , pp. 262-272
    • Landwehrmeyer, G.B.1    Dubois, B.2    de Yebenes, J.G.3
  • 99
    • 0017252399 scopus 로고
    • Clonazepam in the treatment of choreiform activity
    • Peiris JB, Boralessa H, Lionel ND. Clonazepam in the treatment of choreiform activity. Med J Aust 1976;1: 225-227.
    • (1976) Med J Aust , vol.1 , pp. 225-227
    • Peiris, J.B.1    Boralessa, H.2    Lionel, N.D.3
  • 101
    • 38549166606 scopus 로고    scopus 로고
    • Short-term continuous infusion of apomorphine hydrochloride for treatment of Huntington's chorea: a double blind, randomized cross-over trial
    • Vitale C, Marconi S, Di ML, et al. Short-term continuous infusion of apomorphine hydrochloride for treatment of Huntington's chorea: a double blind, randomized cross-over trial. Mov Disord 2007;22: 2359-2364.
    • (2007) Mov Disord , vol.22 , pp. 2359-2364
    • Vitale, C.1    Marconi, S.2    Di, M.L.3
  • 102
    • 0018100179 scopus 로고
    • Apomorphine hydrochloride-induced improvement in Huntington's chorea: stimulation of dopamine receptor
    • Corsini GU, Onali P, Masala C, Cianchetti C, Mangoni A, Gessa G. Apomorphine hydrochloride-induced improvement in Huntington's chorea: stimulation of dopamine receptor. Arch Neurol 1978;35: 27-30.
    • (1978) Arch Neurol , vol.35 , pp. 27-30
    • Corsini, G.U.1    Onali, P.2    Masala, C.3    Cianchetti, C.4    Mangoni, A.5    Gessa, G.6
  • 103
    • 0016158978 scopus 로고
    • Huntington's chorea: the rigid form (Westphal variant) treated with levodopa
    • Low PA, Allsop JL, Halmagyi GM. Huntington's chorea: the rigid form (Westphal variant) treated with levodopa. Med J Aust 1974;1: 393-394.
    • (1974) Med J Aust , vol.1 , pp. 393-394
    • Low, P.A.1    Allsop, J.L.2    Halmagyi, G.M.3
  • 104
    • 0015691076 scopus 로고
    • Huntington's chorea-the rigid form (Westphal variant) treated with l-DOPA: a case report
    • Low PA, Allsop JL. Huntington's chorea-the rigid form (Westphal variant) treated with l-DOPA: a case report. Proc Aust Assoc Neurol 1973;10: 45-46.
    • (1973) Proc Aust Assoc Neurol , vol.10 , pp. 45-46
    • Low, P.A.1    Allsop, J.L.2
  • 105
    • 3042590648 scopus 로고    scopus 로고
    • Amantadine in the akinetic-rigid variant of Huntington's disease
    • Magnet MK, Bonelli RM, Kapfhammer HP. Amantadine in the akinetic-rigid variant of Huntington's disease. Ann Pharmacother 2004;38: 1194-1196.
    • (2004) Ann Pharmacother , vol.38 , pp. 1194-1196
    • Magnet, M.K.1    Bonelli, R.M.2    Kapfhammer, H.P.3
  • 106
    • 0036182828 scopus 로고    scopus 로고
    • Pramipexole ameliorates neurologic and psychiatric symptoms in a Westphal variant of Huntington's disease
    • Bonelli RM, Niederwieser G, Diez J, Gruber A, Költringer P. Pramipexole ameliorates neurologic and psychiatric symptoms in a Westphal variant of Huntington's disease. Clin Neuropharmacol 2002;25: 58-60.
    • (2002) Clin Neuropharmacol , vol.25 , pp. 58-60
    • Bonelli, R.M.1    Niederwieser, G.2    Diez, J.3    Gruber, A.4    Költringer, P.5
  • 107
    • 84865652676 scopus 로고    scopus 로고
    • An international survey-based algorithm for the pharmacologic treatment of irritability in Huntington's disease
    • Groves M, van Duijn E, Anderson K, et al. An international survey-based algorithm for the pharmacologic treatment of irritability in Huntington's disease. PLoS Curr 2011;30: 3.
    • (2011) PLoS Curr , vol.30 , pp. 3
    • Groves, M.1    van Duijn, E.2    Anderson, K.3
  • 108
    • 84863702589 scopus 로고    scopus 로고
    • An international survey-based algorithm for the pharmacologic treatment of obsessive-compulsive behaviors in Huntington's disease
    • Anderson K, Craufurd D, Edmondson MC, et al. An international survey-based algorithm for the pharmacologic treatment of obsessive-compulsive behaviors in Huntington's disease. PLoS Curr 2011;20: 3.
    • (2011) PLoS Curr , vol.20 , pp. 3
    • Anderson, K.1    Craufurd, D.2    Edmondson, M.C.3
  • 109
    • 84893093668 scopus 로고    scopus 로고
    • Accessed August 9, 2013
    • www. clinicaltrials. gov. Accessed August 9, 2013.
  • 110
    • 76149084493 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of latrepirdine in Huntington disease
    • Kieburtz K, McDermott MP, Voss TS, et al. A randomized, placebo-controlled trial of latrepirdine in Huntington disease. Arch Neurol 2010;67: 154-160.
    • (2010) Arch Neurol , vol.67 , pp. 154-160
    • Kieburtz, K.1    McDermott, M.P.2    Voss, T.S.3
  • 111
    • 61449249687 scopus 로고    scopus 로고
    • Randomized controlled trial of ethyl-eicosapentaenoic acid in Huntington disease: the TREND-HD study
    • Huntington Study Group TREND-HD Investigators
    • Huntington Study Group TREND-HD Investigators. Randomized controlled trial of ethyl-eicosapentaenoic acid in Huntington disease: the TREND-HD study. Arch Neurol 2008;65: 1582-1589.
    • (2008) Arch Neurol , vol.65 , pp. 1582-1589
  • 112
    • 33750837262 scopus 로고    scopus 로고
    • Nabilone could treat chorea and irritability in Huntington's disease
    • Curtis A, Rickards H. Nabilone could treat chorea and irritability in Huntington's disease. J Neuropsychiatry Clin Neurosci 2006;18: 553-554.
    • (2006) J Neuropsychiatry Clin Neurosci , vol.18 , pp. 553-554
    • Curtis, A.1    Rickards, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.