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Volumn 61, Issue 11, 2003, Pages 1551-1556

Dosage effects of riluzole in Huntington's disease: A multicenter placebo-controlled study

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; PLACEBO; RILUZOLE;

EID: 0345600893     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000096019.71649.2b     Document Type: Article
Times cited : (118)

References (39)
  • 1
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993;72:971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 2
    • 0029968460 scopus 로고    scopus 로고
    • Trinucleotide repeats in neurogenetic disorders
    • Paulson HL, Fischbeck KH. Trinucleotide repeats in neurogenetic disorders. Annu Rev Neurosci 1996;19:79-107.
    • (1996) Annu Rev Neurosci , vol.19 , pp. 79-107
    • Paulson, H.L.1    Fischbeck, K.H.2
  • 3
    • 0345473574 scopus 로고    scopus 로고
    • Huntington's disease: Clinical features and therapy
    • Watts RL, Koller WC, eds. New York: McGraw-Hill
    • Marshall FJ, Shoulson I. Huntington's disease: clinical features and therapy. In: Watts RL, Koller WC, eds. Movement disorders: neurologic principles and practice. New York: McGraw-Hill, 1997:491-502.
    • (1997) Movement Disorders: Neurologic Principles and Practice , pp. 491-502
    • Marshall, F.J.1    Shoulson, I.2
  • 5
    • 0026684333 scopus 로고
    • The epidemiology of Huntington's disease
    • Harper PS. The epidemiology of Huntington's disease. Hum Genet 1992;89:365-376.
    • (1992) Hum Genet , vol.89 , pp. 365-376
    • Harper, P.S.1
  • 6
  • 7
    • 0026490217 scopus 로고
    • Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo
    • Cheramy A, Barbeito L, Godeheu G, Glowinski J. Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo. Neurosci Lett 1992;147:209-212.
    • (1992) Neurosci Lett , vol.147 , pp. 209-212
    • Cheramy, A.1    Barbeito, L.2    Godeheu, G.3    Glowinski, J.4
  • 8
    • 0027213025 scopus 로고
    • Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes
    • Debono MW, LeGuern J, Canton T, et al. Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes. Eur J Pharmacol 1993;235:283-289.
    • (1993) Eur J Pharmacol , vol.235 , pp. 283-289
    • Debono, M.W.1    LeGuern, J.2    Canton, T.3
  • 9
    • 0028170251 scopus 로고
    • Neuroprotective effects of riluzole on N-methyl-D-aspartate- or veratridine-induced neurotoxicity in rat hippocampal slices
    • Malgouris C, Daniel M, Doble A. Neuroprotective effects of riluzole on N-methyl-D-aspartate- or veratridine-induced neurotoxicity in rat hippocampal slices. Eur J Pharmacol 1994;177:95-99.
    • (1994) Eur J Pharmacol , vol.177 , pp. 95-99
    • Malgouris, C.1    Daniel, M.2    Doble, A.3
  • 10
    • 0026334826 scopus 로고
    • Riluzole specifically blocks inactivated Na channels in myelinated nerve fibers
    • Benoit E, Escande D. Riluzole specifically blocks inactivated Na channels in myelinated nerve fibers. Pflugers Arch 1991;419:603-609.
    • (1991) Pflugers Arch , vol.419 , pp. 603-609
    • Benoit, E.1    Escande, D.2
  • 11
    • 0020702374 scopus 로고
    • Quinolinic acid: An endogenous metabolite that produces axon-sparing lesions in rat brain
    • Schwarcz R, Whetsell WO, Mangano RM. Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain. Science 1982;219:316-318.
    • (1982) Science , vol.219 , pp. 316-318
    • Schwarcz, R.1    Whetsell, W.O.2    Mangano, R.M.3
  • 12
    • 0022446150 scopus 로고
    • Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
    • Beal MF, Kowall NW, Ellison DW, Mazurek MF, Swartz KJ, Martin JB. Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature 1986;321:168-171.
    • (1986) Nature , vol.321 , pp. 168-171
    • Beal, M.F.1    Kowall, N.W.2    Ellison, D.W.3    Mazurek, M.F.4    Swartz, K.J.5    Martin, J.B.6
  • 13
    • 0026043565 scopus 로고
    • Chronic quinolinic acid lesions in rats closely resemble Huntington's disease
    • Beal MF, Ferrante RJ, Swartz KJ, Kowall NW. Chronic quinolinic acid lesions in rats closely resemble Huntington's disease. J Neurosci 1991;11:1649-1659.
    • (1991) J Neurosci , vol.11 , pp. 1649-1659
    • Beal, M.F.1    Ferrante, R.J.2    Swartz, K.J.3    Kowall, N.W.4
  • 14
    • 0028803390 scopus 로고
    • Effect of riluzole on quinolinate-induced neuronal damage in rats: Comparison with blockers of glutamatergic neurotransmission
    • Mary V, Wahl F, Stutzmann JM. Effect of riluzole on quinolinate-induced neuronal damage in rats: comparison with blockers of glutamatergic neurotransmission. Neurosci Lett 1995;201:92-96.
    • (1995) Neurosci Lett , vol.201 , pp. 92-96
    • Mary, V.1    Wahl, F.2    Stutzmann, J.M.3
  • 15
    • 0027433553 scopus 로고
    • Neurochemical and histological characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
    • Beal MF, Brouillet E, Jenkins BG, et al. Neurochemical and histological characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. J Neurosci 1993;13:4181-4192.
    • (1993) J Neurosci , vol.13 , pp. 4181-4192
    • Beal, M.F.1    Brouillet, E.2    Jenkins, B.G.3
  • 16
    • 0030764219 scopus 로고    scopus 로고
    • Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats
    • Guyot MC, Palfi S, Stutzmann JM, Maziere M, Hantraye P, Brouillet E. Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats. Neuroscience 1997;81:141-149.
    • (1997) Neuroscience , vol.81 , pp. 141-149
    • Guyot, M.C.1    Palfi, S.2    Stutzmann, J.M.3    Maziere, M.4    Hantraye, P.5    Brouillet, E.6
  • 17
    • 0029118136 scopus 로고
    • Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates
    • Brouillet E, Hantraye P, Ferrante RJ, et al. Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates. Proc Natl Acad Sci USA 1995;92:7105-7109.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7105-7109
    • Brouillet, E.1    Hantraye, P.2    Ferrante, R.J.3
  • 19
    • 0031193501 scopus 로고    scopus 로고
    • Riluzole reduces incidence of abnormal movements but not striatal cell death in a primate model of progressive striatal degeneration
    • Palfi S, Riche D, Brouillet E, et al. Riluzole reduces incidence of abnormal movements but not striatal cell death in a primate model of progressive striatal degeneration. Exp Neurol 1997;146:135-141.
    • (1997) Exp Neurol , vol.146 , pp. 135-141
    • Palfi, S.1    Riche, D.2    Brouillet, E.3
  • 20
    • 0033437155 scopus 로고    scopus 로고
    • Riluzole therapy in Huntington's disease (HD)
    • Rosas HD, Koroshetz WJ, Jenkins BG, et al. Riluzole therapy in Huntington's disease (HD). Mov Disord 1999;14:326-330.
    • (1999) Mov Disord , vol.14 , pp. 326-330
    • Rosas, H.D.1    Koroshetz, W.J.2    Jenkins, B.G.3
  • 21
    • 0034796483 scopus 로고    scopus 로고
    • Riluzole in Huntington's disease (HD): An open label study with one year follow up
    • Seppi K, Mueller J, Bodner T, et al. Riluzole in Huntington's disease (HD): an open label study with one year follow up. J Neurol 2001;248:866-869.
    • (2001) J Neurol , vol.248 , pp. 866-869
    • Seppi, K.1    Mueller, J.2    Bodner, T.3
  • 22
    • 0018303366 scopus 로고
    • Huntington's disease: Clinical care and evaluation
    • Shoulson I, Fahn S. Huntington's disease: clinical care and evaluation. Neurology 1979;29:1-3.
    • (1979) Neurology , vol.29 , pp. 1-3
    • Shoulson, I.1    Fahn, S.2
  • 23
    • 0000177578 scopus 로고
    • Assessment of functional capacity in neurodegenerative movement disorders: Huntington's disease as a prototype
    • Munsat TL, ed. Boston: Butterworths
    • Shoulson I, Kurian R, Rubin AJ, et al. Assessment of functional capacity in neurodegenerative movement disorders: Huntington's disease as a prototype. In: Munsat TL, ed. Quantification of neurological deficit. Boston: Butterworths, 1989:271-283.
    • (1989) Quantification of Neurological Deficit , pp. 271-283
    • Shoulson, I.1    Kurian, R.2    Rubin, A.J.3
  • 24
    • 9244263519 scopus 로고    scopus 로고
    • A controlled trial of remacemide hydrochloride in Huntington's disease
    • Kieburtz K, Feigin A, McDermott M, et al. A controlled trial of remacemide hydrochloride in Huntington's disease. Mov Disord 1996;11:272-277.
    • (1996) Mov Disord , vol.11 , pp. 272-277
    • Kieburtz, K.1    Feigin, A.2    McDermott, M.3
  • 25
    • 85009332113 scopus 로고    scopus 로고
    • Unified Huntington's Disease Rating Scale. Reliability and consistency
    • Huntington Study Group. Unified Huntington's Disease Rating Scale. Reliability and consistency. Mov Disord 1996;11:136-142.
    • (1996) Mov Disord , vol.11 , pp. 136-142
  • 26
    • 0034711708 scopus 로고    scopus 로고
    • Rate of functional decline in Huntington's disease
    • Marder K, Zhao H, Myers RH, et al. Rate of functional decline in Huntington's disease. Neurology 2000;54:452-458.
    • (2000) Neurology , vol.54 , pp. 452-458
    • Marder, K.1    Zhao, H.2    Myers, R.H.3
  • 28
    • 57049145197 scopus 로고
    • Studies of interference in serial verbal reactions
    • Stroop JR. Studies of interference in serial verbal reactions. J Exp Psychol 1935;18:643-662.
    • (1935) J Exp Psychol , vol.18 , pp. 643-662
    • Stroop, J.R.1
  • 30
    • 0344625374 scopus 로고    scopus 로고
    • Safety and tolerability of the free-radical scavenger OPC-14117 in Huntington's disease
    • Huntington Study Group. Safety and tolerability of the free-radical scavenger OPC-14117 in Huntington's disease. Neurology 1998;50:1366-1373.
    • (1998) Neurology , vol.50 , pp. 1366-1373
  • 31
    • 0017042882 scopus 로고
    • Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design
    • Peto R, Pike MC, Armitage P, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design. Br J Cancer 1976;34:585-612.
    • (1976) Br J Cancer , vol.34 , pp. 585-612
    • Peto, R.1    Pike, M.C.2    Armitage, P.3
  • 32
    • 0025298139 scopus 로고
    • Primate models of movement disorders of basal ganglia origin
    • DeLong MR. Primate models of movement disorders of basal ganglia origin. Trends Neurosci 1990;13:281-285.
    • (1990) Trends Neurosci , vol.13 , pp. 281-285
    • DeLong, M.R.1
  • 33
    • 0033595502 scopus 로고    scopus 로고
    • Influence of lamotrigine on progression of early Huntington disease: A randomized clinical trial
    • Kremer B, Clark CM, Almqvist EW, et al. Influence of lamotrigine on progression of early Huntington disease: a randomized clinical trial. Neurology 1999;53:1000-1011.
    • (1999) Neurology , vol.53 , pp. 1000-1011
    • Kremer, B.1    Clark, C.M.2    Almqvist, E.W.3
  • 34
    • 85009226418 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease
    • Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
    • (2001) Neurology , vol.57 , pp. 397-404
  • 35
    • 4243580262 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled crossover study of the effect of amantadine on chorea in Huntington's disease
    • Verhagen L, Morris M, Farmer C, Gillespie M, Wuu J, Chase TN. A double-blind, placebo-controlled crossover study of the effect of amantadine on chorea in Huntington's disease. Neurology 2001;56(suppl 3): A386.
    • (2001) Neurology , vol.56 , Issue.SUPPL. 3
    • Verhagen, L.1    Morris, M.2    Farmer, C.3    Gillespie, M.4    Wuu, J.5    Chase, T.N.6
  • 36
    • 0024556360 scopus 로고
    • A controlled clinical trial of baclofen in Huntington's disease
    • Shoulson I, Odoroff C, Oakes D, et al. A controlled clinical trial of baclofen in Huntington's disease. Ann Neurol 1989;25:252-259.
    • (1989) Ann Neurol , vol.25 , pp. 252-259
    • Shoulson, I.1    Odoroff, C.2    Oakes, D.3
  • 37
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • Bensimon G, Lacomblez L, Meininger V, ALS/Riluzole Study Group. A controlled trial of riluzole in amyotrophic lateral sclerosis. N Engl J Med 1994;330:585-591.
    • (1994) N Engl J Med , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 38
    • 0029977337 scopus 로고    scopus 로고
    • Dose-ranging study of riluzole in amyotrophic lateral sclerosis
    • Lacomblez L, Bensimon G, Leigh PN, Guillet P, Meininger V, ALS/ Riluzole Study Group. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Lancet 1996;347:1425-1431.
    • (1996) Lancet , vol.347 , pp. 1425-1431
    • Lacomblez, L.1    Bensimon, G.2    Leigh, P.N.3    Guillet, P.4    Meininger, V.5


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