Targeting cancer cells by using an antireceptor antibody-photosensitizer fusion protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 23, 2009, Pages 9221-9225

  Serebrovskaya, Ekaterina O ^a   Edelweiss, Eveline F ^a   Stremovskiy, Oleg A ^a   Lukyanov, Konstantin A ^a   Chudakov, Dmitry M ^a   Deyev, Sergey M ^a  

^a SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

KillerRed; Phototoxicity; Reactive oxygen species

Indexed keywords

CISPLATIN; HUMAN MONOCLONAL ANTIBODY; HYBRID PROTEIN; KILLER RED; MONOCLONAL ANTIBODY 4D5 SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY KILLER RED HYBRID PROTEIN; PHOTOSENSITIZING AGENT; REACTIVE OXYGEN METABOLITE; RECOMBINANT PROTEIN; RED FLUORESCENT PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CANCER CELL; CELL VIABILITY; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; FLUORESCENT LIGHTING; GENE OVEREXPRESSION; GENETIC CODE; HUMAN; HUMAN CELL; IRRADIATION; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPRODUCIBILITY; TARGET CELL;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; FEMALE; HUMANS; IMMUNOGLOBULIN FRAGMENTS; OVARIAN NEOPLASMS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; RECOMBINANT FUSION PROTEINS;

EID: 67249146583     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904140106     Document Type: Article

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