Transcription factor E3, a major regulator of mast cell-mediated allergic response

Journal of Allergy and Clinical Immunology

Volumn 129, Issue 5, 2012, Pages

  Yagil, Zohar ^a   Hadad Erlich, Tal ^a   Ofir Birin, Yifat ^a   Tshori, Sagi ^b   Kay, Gillian ^a   Yekhtin, Zanna ^b   Fisher, David E ^c   Cheng, Chang ^d   Wong, W S Fred ^d,e   Hartmann, Karin ^f   Razin, Ehud ^a   Nechushtan, Hovav ^b  

^a HEBREW UNIVERSITY   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^f UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Allergy; cytokine secretion; degranulation; histamine; mast cells; transcription factor E3 knockout mice

Indexed keywords

CYTOKINE; FC RECEPTOR; STEM CELL FACTOR; TOLONIUM CHLORIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E3; UNCLASSIFIED DRUG;

ALLERGIC DISEASE; ALLERGY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL COUNT; CELL FUNCTION; CONTROLLED STUDY; CYTOKINE RELEASE; FLUORESCENCE ACTIVATED CELL SORTING; HISTAMINE BLOOD LEVEL; IMMUNE RESPONSE; IN VIVO STUDY; KNOCKOUT MOUSE; LUNG; MAST CELL; MAST CELL DEGRANULATION; MEDIATOR RELEASE; MOUSE; NONHUMAN; PERITONEUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN; WILD TYPE;

EID: 84860426179     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.11.051     Document Type: Article

References (38)

1. T.J. Hemesath, E. Steingrimsson, G. McGill, M.J. Hansen, J. Vaught, and C.A. Hodgkinson Microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family Genes Dev 8 1994 2770 2780
2. Y. Kitamura, E. Morii, T. Jippo, and A. Ito Regulation of mast cell phenotype by MITF Int Arch Allergy Immunol 127 2002 106 109
3. Y. Kitamura, E. Morii, T. Jippo, and A. Ito Effect of MITF on mast cell differentiation Mol Immunol 38 2002 1173 1176
4. Y. Kitamura, K. Oboki, and A. Ito Molecular mechanisms of mast cell development Immunol Allergy Clin North Am 26 2006 387 405 v
5. X. Hua, X. Liu, D.O. Ansari, and H.F. Lodish Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene Genes Dev 12 1998 3084 3095
6. K.N. Weilbaecher, G. Motyckova, W.E. Huber, C.M. Takemoto, T.J. Hemesath, and Y. Xu Linkage of M-CSF signaling to Mitf, TFE3, and the osteoclast defect in Mitf(mi/mi) mice Mol Cell 8 2001 749 758
7. E. Steingrimsson, L. Tessarollo, B. Pathak, L. Hou, H. Arnheiter, and N.G. Copeland Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development Proc Natl Acad Sci U S A 99 2002 4477 4482
8. C. Verastegui, C. Bertolotto, K. Bille, P. Abbe, J.P. Ortonne, and R. Ballotti TFE3, a transcription factor homologous to microphthalmia, is a potential transcriptional activator of tyrosinase and TyrpI genes Mol Endocrinol 14 2000 449 456
9. C. Huan, M.L. Kelly, R. Steele, I. Shapira, S.R. Gottesman, and C.A. Roman Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity Nat Immunol 7 2006 1082 1091
10. K. Merrell, S. Wells, A. Henderson, J. Gorman, F. Alt, and A. Stall The absence of the transcription activator TFE3 impairs activation of B cells in vivo Mol Cell Biol 17 1997 3335 3344
11. A. Tsicopoulos, and M. Joseph The role of CD23 in allergic disease Clin Exp Allergy 30 2000 602 605
12. C.L. Hershey, and D.E. Fisher Mitf and Tfe3: members of a b-HLH-ZIP transcription factor family essential for osteoclast development and function Bone 34 2004 689 696
13. C.A. Hodgkinson, K.J. Moore, A. Nakayama, E. Steingrimsson, N.G. Copeland, and N.A. Jenkins Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein Cell 74 1993 395 404
14. S. Tshori, A. Sonnenblick, N. Yannay-Cohen, G. Kay, H. Nechushtan, and E. Razin Microphthalmia transcription factor isoforms in mast cells and the heart Mol Cell Biol 27 2007 3911 3919
15. K. Isozaki, T. Tsujimura, S. Nomura, E. Morii, U. Koshimizu, and Y. Nishimune Cell type-specific deficiency of c-kit gene expression in mutant mice of mi/mi genotype Am J Pathol 145 1994 827 836
16. K. Takahashi, C. Nishiyama, M. Nishiyama, K. Okumura, C. Ra, and Y. Ohtake A complex composed of USF1 and USF2 activates the human FcepsilonRI alpha chain expression via a CAGCTG element in the first intron Eur J Immunol 31 2001 590 599
17. E. Razin, J.M. Mencia-Huerta, R.A. Lewis, E.J. Corey, and K.F. Austen Generation of leukotriene C4 from a subclass of mast cells differentiated in vitro from mouse bone marrow Proc Natl Acad Sci U S A 79 1982 4665 4667
18. Y. Kitamura, E. Morii, H. Ogihara, T. Jippo, and A. Ito Mutant mice: a useful tool for studying the development of mast cells Int Arch Allergy Immunol 124 2001 16 19
19. K.C. Mansky, S. Sulzbacher, G. Purdom, L. Nelsen, D.A. Hume, and M. Rehli The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter J Leukoc Biol 71 2002 304 310
20. C.M. Takemoto, Y.J. Yoon, and D.E. Fisher The identification and functional characterization of a novel mast cell isoform of the microphthalmia-associated transcription factor J Biol Chem 277 2002 30244 30252
21. H. Nechushtan, Z. Zhang, and E. Razin Microphthalmia (mi) in murine mast cells: regulation of its stimuli-mediated expression on the translational level Blood 89 1997 2999 3008
22. J.H. Hallsson, J. Favor, C. Hodgkinson, T. Glaser, M.L. Lamoreux, and R. Magnusdottir Genomic, transcriptional and mutational analysis of the mouse microphthalmia locus Genetics 155 2000 291 300
23. N.S. Yee, I. Paek, and P. Besmer Role of kit-ligand in proliferation and suppression of apoptosis in mast cells: basis for radiosensitivity of white spotting and steel mutant mice J Exp Med 179 1994 1777 1787
24. S.E. Artandi, C. Cooper, A. Shrivastava, and K. Calame The basic helix-loop-helix-zipper domain of TFE3 mediates enhancer-promoter interaction Mol Cell Biol 14 1994 7704 7716
25. Y.A. Mekori, C.K. Oh, and D.D. Metcalfe IL-3-dependent murine mast cells undergo apoptosis on removal of IL-3. Prevention of apoptosis by c-kit ligand J Immunol 151 1993 3775 3784
26. S.B. Hong, H. Oh, V.A. Valera, M. Baba, L.S. Schmidt, and W.M. Linehan Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization PLoS One 5 2010 e15793
27. Y.N. Lee, S. Brandal, P. Noel, E. Wentzel, J.T. Mendell, and M.A. McDevitt KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation Blood 117 2011 3629 3640
28. C. Levy, M. Khaled, K.C. Robinson, R.A. Veguilla, P.H. Chen, and S. Yokoyama Lineage-specific transcriptional regulation of DICER by MITF in melanocytes Cell 141 2010 994 1005
29. C. Levy, H. Nechushtan, and E. Razin A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor J Biol Chem 277 2002 1962 1966
30. E. Razin, Z.C. Zhang, H. Nechushtan, S. Frenkel, Y.N. Lee, and R. Arudchandran Suppression of microphthalmia transcriptional activity by its association with protein kinase C-interacting protein 1 in mast cells J Biol Chem 274 1999 34272 34276
31. M. Wu, T.J. Hemesath, C.M. Takemoto, M.A. Horstmann, A.G. Wells, and E.R. Price c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi Genes Dev 14 2000 301 312
32. W. Xu, L. Gong, M.M. Haddad, O. Bischof, J. Campisi, and E.T. Yeh Regulation of microphthalmia-associated transcription factor MITF protein levels by association with the ubiquitin-conjugating enzyme hUBC9 Exp Cell Res 255 2000 135 143
33. T. Schwarz, S. Murphy, C. Sohn, and K.C. Mansky C-TAK1 interacts with microphthalmia-associated transcription factor, Mitf, but not the related family member Tfe3 Biochem Biophys Res Commun 394 2010 890 895
34. H.J. Gould, and B.J. Sutton IgE in allergy and asthma today Nat Rev Immunol 8 2008 205 217
35. N.S. Yee, I. Paek, and P. Besmer Role of kit-ligand in proliferation and suppression of apoptosis in mast cells: basis for radiosensitivity of white spotting and steel mutant mice J Exp Med 179 1994 1777 1787
36. E. Razin, C. Cordon-Cardo, and R.A. Good Growth of a pure population of mouse mast cells in vitro with conditioned medium derived from concanavalin A-stimulated splenocytes Proc Natl Acad Sci U S A 78 1981 2559 2561
37. C.L. Hershey, and D.E. Fisher Mitf and Tfe3: members of a b-HLH-ZIP transcription factor family essential for osteoclast development and function Bone 34 2004 689 696
38. S. Tshori, A. Sonnenblick, N. Yannay-Cohen, G. Kay, H. Nechushtan, and E. Razin Microphthalmia transcription factor isoforms in mast cells and the heart Mol Cell Biol 27 2007 3911 3919