Selection and adaptation in the human genome

Annual Review of Genomics and Human Genetics

Volumn 14, Issue , 2013, Pages 467-489

  Fu, Wenqing ^a   Akey, Joshua M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Adaptive evolution; Hard sweep; Mutation load; Polygenic selection; Purifying selection; Soft sweep

Indexed keywords

HLA ANTIGEN; LACTASE; STAT2 PROTEIN;

ADAPTATION; ALTERNATIVE RNA SPLICING; ALTITUDE DISEASE; BALANCING SELECTION; CHIMPANZEE; DNA METHYLATION; DNA SEQUENCE; EVOLUTION; GENE CONTROL; GENE CONVERSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; GORILLA; HAPLOTYPE; HOMOZYGOSITY; HUMAN; HUMAN CHROMOSOME; HUMAN GENOME; MACACA; NATURAL SELECTION; NONHUMAN; ORANG UTAN; PHENOTYPIC VARIATION; PROMOTER REGION; PURIFYING SELECTION; REVIEW; SELECTIVE SWEEP; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; EVOLUTION, MOLECULAR; GENOME, HUMAN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HOMINIDAE; HUMANS; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 84884315340     PISSN: 15278204     EISSN: 1545293X     Source Type: Book Series    
DOI: 10.1146/annurev-genom-091212-153509     Document Type: Review

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