Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells

Apoptosis

Volumn 19, Issue 1, 2014, Pages 224-240

  Han, Cho Rong ^a   Jun, Do Youn ^b   Lee, Ji Young ^a   Kim, Young Ho ^a  

^a Kyungpook National University   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

Author keywords

Apoptosis; Association of Bcl 2 with Bak or Bim; Bak activation; Cdk1 activation; Phosphorylation of Bcl 2 and Bim; Prometaphase arrest

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BIM PROTEIN; CASPASE 3; CASPASE 9; CYCLIN B1; HYDROXYUREA; NOCODAZOLE; PROTEIN BAK; PROTEIN BCL 2; ROSCOVITINE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; G1 PHASE CELL CYCLE CHECKPOINT; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MITOCHONDRION; MITOSIS INHIBITION; PHOSPHORYLATION; PRIORITY JOURNAL; PROMETAPHASE; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; S PHASE CELL CYCLE CHECKPOINT;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; HUMANS; JURKAT CELLS; LEUKEMIA, T-CELL; M PHASE CELL CYCLE CHECKPOINTS; MEMBRANE PROTEINS; MITOCHONDRIA; NOCODAZOLE; PHOSPHORYLATION; PROMETAPHASE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84892801477     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0928-1     Document Type: Article

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