Apoptogenic activity of auraptene of Zanthoxylum schinifolium toward human acute leukemia Jurkat T cells is associated with ER stress-mediated caspase-8 activation that stimulates mitochondria-dependent or -independent caspase cascade

Carcinogenesis

Volumn 28, Issue 6, 2007, Pages 1303-1313

  Jun, Do Y ^a   Kim, Jun S ^a   Park, Hae S ^a   Han, Cho R ^a   Fang, Zhe ^b   Woo, Mi H ^b   Rhee, In K ^a   Kim, Young H ^a  

^a Kyungpook National University   (South Korea)

^b Catholic University of Daegu   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; AURAPTENE; CALPASTATIN; CASPASE 12; CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; CYTOCHROME C; DICHLOROMETHANE; DNA FRAGMENT; FAS ANTIBODY; FLICE INHIBITORY PROTEIN; NEUTRALIZING ANTIBODY; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT EXTRACT; PROTEIN BCL XL; PROTEIN BID; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ZANTHOXYLUM SCHINIFOLIUM EXTRACT;

APOPTOSIS; ARTICLE; CELL MEMBRANE PERMEABILITY; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME RELEASE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL LINE; MITOCHONDRION; PRIORITY JOURNAL; T LYMPHOCYTE; WESTERN BLOTTING; ZANTHOXYLUM; ZANTHOXYLUM SCHINIFOLIUM;

APOPTOSIS; CASPASE 8; COUMARINS; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HUMANS; JURKAT CELLS; LEUKEMIA, T-CELL, ACUTE; MITOCHONDRIA; PHYTOTHERAPY; SIGNAL TRANSDUCTION; ZANTHOXYLUM;

EID: 34447303538     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm028     Document Type: Article

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