-
1
-
-
70350771277
-
Centrioles, centrosomes, and cilia in health and disease
-
Nigg EA, Raff JW, (2009) Centrioles, centrosomes, and cilia in health and disease. Cell 139: 663-678.
-
(2009)
Cell
, vol.139
, pp. 663-678
-
-
Nigg, E.A.1
Raff, J.W.2
-
2
-
-
33746891890
-
The primary cilium as the cell's antenna: signaling at a sensory organelle
-
Singla V, Reiter JF, (2006) The primary cilium as the cell's antenna: signaling at a sensory organelle. Science 313: 629-633.
-
(2006)
Science
, vol.313
, pp. 629-633
-
-
Singla, V.1
Reiter, J.F.2
-
3
-
-
84859264546
-
The ciliary transition zone: from morphology and molecules to medicine
-
Czarnecki PG, Shah JV, (2012) The ciliary transition zone: from morphology and molecules to medicine. Trends Cell Biol 22(4): 201-10.
-
(2012)
Trends Cell Biol
, vol.22
, Issue.4
, pp. 201-210
-
-
Czarnecki, P.G.1
Shah, J.V.2
-
4
-
-
67649635952
-
Intraflagellar transport and the generation of dynamic, structurally and functionally diverse cilia
-
Silverman MA, Leroux MR, (2009) Intraflagellar transport and the generation of dynamic, structurally and functionally diverse cilia. Trends Cell Biol 19: 306-316.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 306-316
-
-
Silverman, M.A.1
Leroux, M.R.2
-
5
-
-
79953032655
-
Ciliogenesis: building the cell's antenna
-
Ishikawa H, Marshall WF, (2011) Ciliogenesis: building the cell's antenna. Nat Rev Mol Cell Biol 12: 222-234.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 222-234
-
-
Ishikawa, H.1
Marshall, W.F.2
-
6
-
-
63049116544
-
The vertebrate primary cilium in development, homeostasis, and disease
-
Gerdes JM, Davis EE, Katsanis N, (2009) The vertebrate primary cilium in development, homeostasis, and disease. Cell 137: 32-45.
-
(2009)
Cell
, vol.137
, pp. 32-45
-
-
Gerdes, J.M.1
Davis, E.E.2
Katsanis, N.3
-
7
-
-
70449625440
-
Making sense of cilia in disease: the human ciliopathies
-
Baker K, Beales PL, (2009) Making sense of cilia in disease: the human ciliopathies. Am J Med Genet C Semin Med Genet 151C: 281-295.
-
(2009)
Am J Med Genet C Semin Med Genet
, vol.151 C
, pp. 281-295
-
-
Baker, K.1
Beales, P.L.2
-
8
-
-
33748335482
-
The ciliary proteome database: an integrated community resource for the genetic and functional dissection of cilia
-
Gherman A, Davis EE, Katsanis N, (2006) The ciliary proteome database: an integrated community resource for the genetic and functional dissection of cilia. Nat Genet 38: 961-962.
-
(2006)
Nat Genet
, vol.38
, pp. 961-962
-
-
Gherman, A.1
Davis, E.E.2
Katsanis, N.3
-
10
-
-
35548974826
-
Cep164, a novel centriole appendage protein required for primary cilium formation
-
Graser S, Stierhof YD, Lavoie SB, Gassner OS, Lamla S, et al. (2007) Cep164, a novel centriole appendage protein required for primary cilium formation. J Cell Biol 179: 321-330.
-
(2007)
J Cell Biol
, vol.179
, pp. 321-330
-
-
Graser, S.1
Stierhof, Y.D.2
Lavoie, S.B.3
Gassner, O.S.4
Lamla, S.5
-
11
-
-
77951128108
-
Functional genomic screen for modulators of ciliogenesis and cilium length
-
Kim J, Lee JE, Heynen-Genel S, Suyama E, Ono K, et al. (2010) Functional genomic screen for modulators of ciliogenesis and cilium length. Nature 464: 1048-1051.
-
(2010)
Nature
, vol.464
, pp. 1048-1051
-
-
Kim, J.1
Lee, J.E.2
Heynen-Genel, S.3
Suyama, E.4
Ono, K.5
-
12
-
-
79953307660
-
Functional characterization of putative cilia genes by high-content analysis
-
Lai CK, Gupta N, Wen X, Rangell L, Chih B, et al. (2011) Functional characterization of putative cilia genes by high-content analysis. Mol Biol Cell 22: 1104-1119.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 1104-1119
-
-
Lai, C.K.1
Gupta, N.2
Wen, X.3
Rangell, L.4
Chih, B.5
-
15
-
-
79951829447
-
Centriolar satellites are assembly points for proteins implicated in human ciliopathies, including oral-facial-digital syndrome 1
-
Lopes CA, Prosser SL, Romio L, Hirst RA, O'Callaghan C, et al. (2011) Centriolar satellites are assembly points for proteins implicated in human ciliopathies, including oral-facial-digital syndrome 1. J Cell Sci 124: 600-612.
-
(2011)
J Cell Sci
, vol.124
, pp. 600-612
-
-
Lopes, C.A.1
Prosser, S.L.2
Romio, L.3
Hirst, R.A.4
O'Callaghan, C.5
-
16
-
-
0033002657
-
Role for microtubules in centrosome doubling in Chinese hamster ovary cells
-
Balczon R, Varden CE, Schroer TA, (1999) Role for microtubules in centrosome doubling in Chinese hamster ovary cells. Cell Motil Cytoskeleton 42: 60-72.
-
(1999)
Cell Motil Cytoskeleton
, vol.42
, pp. 60-72
-
-
Balczon, R.1
Varden, C.E.2
Schroer, T.A.3
-
17
-
-
80054849116
-
Centriolar satellites: busy orbits around the centrosome
-
Barenz F, Mayilo D, Gruss OJ, (2011) Centriolar satellites: busy orbits around the centrosome. Eur J Cell Biol 90: 983-989.
-
(2011)
Eur J Cell Biol
, vol.90
, pp. 983-989
-
-
Barenz, F.1
Mayilo, D.2
Gruss, O.J.3
-
18
-
-
0033615982
-
Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis
-
Kubo A, Sasaki H, Yuba-Kubo A, Tsukita S, Shiina N, (1999) Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis. J Cell Biol 147: 969-980.
-
(1999)
J Cell Biol
, vol.147
, pp. 969-980
-
-
Kubo, A.1
Sasaki, H.2
Yuba-Kubo, A.3
Tsukita, S.4
Shiina, N.5
-
19
-
-
0037191046
-
Assembly of centrosomal proteins and microtubule organization depends on PCM-1
-
Dammermann A, Merdes A, (2002) Assembly of centrosomal proteins and microtubule organization depends on PCM-1. J Cell Biol 159: 255-266.
-
(2002)
J Cell Biol
, vol.159
, pp. 255-266
-
-
Dammermann, A.1
Merdes, A.2
-
20
-
-
20244381625
-
The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression
-
Kim JC, Badano JL, Sibold S, Esmail MA, Hill J, et al. (2004) The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression. Nat Genet 36: 462-470.
-
(2004)
Nat Genet
, vol.36
, pp. 462-470
-
-
Kim, J.C.1
Badano, J.L.2
Sibold, S.3
Esmail, M.A.4
Hill, J.5
-
21
-
-
34250012834
-
A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
-
Nachury MV, Loktev AV, Zhang Q, Westlake CJ, Peranen J, et al. (2007) A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell 129: 1201-1213.
-
(2007)
Cell
, vol.129
, pp. 1201-1213
-
-
Nachury, M.V.1
Loktev, A.V.2
Zhang, Q.3
Westlake, C.J.4
Peranen, J.5
-
22
-
-
84865709186
-
The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium
-
Stowe TR, Wilkinson CJ, Iqbal A, Stearns T, (2012) The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium. Mol Biol Cell 23: 3322-3335.
-
(2012)
Mol Biol Cell
, vol.23
, pp. 3322-3335
-
-
Stowe, T.R.1
Wilkinson, C.J.2
Iqbal, A.3
Stearns, T.4
-
23
-
-
79851497902
-
The gene regulatory cascade linking proneural specification with differentiation in Drosophila sensory neurons
-
Cachero S, Simpson TI, Zur Lage PI, Ma L, Newton FG, et al. (2011) The gene regulatory cascade linking proneural specification with differentiation in Drosophila sensory neurons. PLoS Biol 9: e1000568.
-
(2011)
PLoS Biol
, vol.9
-
-
Cachero, S.1
Simpson, T.I.2
Zur Lage, P.I.3
Ma, L.4
Newton, F.G.5
-
24
-
-
79961136106
-
Dilatory is a Drosophila protein related to AZI1 (CEP131) that is located at the ciliary base and required for cilium formation
-
Ma L, Jarman AP, (2011) Dilatory is a Drosophila protein related to AZI1 (CEP131) that is located at the ciliary base and required for cilium formation. J Cell Sci 124: 2622-2630.
-
(2011)
J Cell Sci
, vol.124
, pp. 2622-2630
-
-
Ma, L.1
Jarman, A.P.2
-
25
-
-
63849188695
-
Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos
-
Wilkinson CJ, Carl M, Harris WA, (2009) Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. BMC Cell Biol 10: 17.
-
(2009)
BMC Cell Biol
, vol.10
, pp. 17
-
-
Wilkinson, C.J.1
Carl, M.2
Harris, W.A.3
-
26
-
-
0346874342
-
Proteomic characterization of the human centrosome by protein correlation profiling
-
Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, et al. (2003) Proteomic characterization of the human centrosome by protein correlation profiling. Nature 426: 570-574.
-
(2003)
Nature
, vol.426
, pp. 570-574
-
-
Andersen, J.S.1
Wilkinson, C.J.2
Mayor, T.3
Mortensen, P.4
Nigg, E.A.5
-
27
-
-
79955009072
-
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods
-
Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, et al. (2011) Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J 30: 1520-1535.
-
(2011)
EMBO J
, vol.30
, pp. 1520-1535
-
-
Jakobsen, L.1
Vanselow, K.2
Skogs, M.3
Toyoda, Y.4
Lundberg, E.5
-
28
-
-
84871742909
-
The centriolar satellite protein Cep131 is important for genome stability
-
Staples CJ, Myers KN, Beveridge RD, Patil AA, Lee AJ, et al. (2012) The centriolar satellite protein Cep131 is important for genome stability. J Cell Sci 125: 4770-4779.
-
(2012)
J Cell Sci
, vol.125
, pp. 4770-4779
-
-
Staples, C.J.1
Myers, K.N.2
Beveridge, R.D.3
Patil, A.A.4
Lee, A.J.5
-
29
-
-
0028804264
-
Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids
-
Aoto H, Tsuchida J, Nishina Y, Nishimune Y, Asano A, et al. (1995) Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids. Eur J Biochem 234: 8-15.
-
(1995)
Eur J Biochem
, vol.234
, pp. 8-15
-
-
Aoto, H.1
Tsuchida, J.2
Nishina, Y.3
Nishimune, Y.4
Asano, A.5
-
30
-
-
67651119997
-
A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability
-
Paulsen RD, Soni DV, Wollman R, Hahn AT, Yee MC, et al. (2009) A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability. Mol Cell 35: 228-239.
-
(2009)
Mol Cell
, vol.35
, pp. 228-239
-
-
Paulsen, R.D.1
Soni, D.V.2
Wollman, R.3
Hahn, A.T.4
Yee, M.C.5
-
31
-
-
34247558062
-
The graded response to Sonic Hedgehog depends on cilia architecture
-
Caspary T, Larkins CE, Anderson KV, (2007) The graded response to Sonic Hedgehog depends on cilia architecture. Dev Cell 12: 767-778.
-
(2007)
Dev Cell
, vol.12
, pp. 767-778
-
-
Caspary, T.1
Larkins, C.E.2
Anderson, K.V.3
-
32
-
-
0034042763
-
The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination
-
Murcia NS, Richards WG, Yoder BK, Mucenski ML, Dunlap JR, et al. (2000) The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination. Development 127: 2347-2355.
-
(2000)
Development
, vol.127
, pp. 2347-2355
-
-
Murcia, N.S.1
Richards, W.G.2
Yoder, B.K.3
Mucenski, M.L.4
Dunlap, J.R.5
-
33
-
-
0034735526
-
Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella
-
Pazour GJ, Dickert BL, Vucica Y, Seeley ES, Rosenbaum JL, et al. (2000) Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol 151: 709-718.
-
(2000)
J Cell Biol
, vol.151
, pp. 709-718
-
-
Pazour, G.J.1
Dickert, B.L.2
Vucica, Y.3
Seeley, E.S.4
Rosenbaum, J.L.5
-
34
-
-
80755175389
-
Characterization of ubiquitination dependent dynamics in growth factor receptor signaling by quantitative proteomics
-
Akimov V, Rigbolt KT, Nielsen MM, Blagoev B, (2011) Characterization of ubiquitination dependent dynamics in growth factor receptor signaling by quantitative proteomics. Mol Biosyst 7: 3223-3233.
-
(2011)
Mol Biosyst
, vol.7
, pp. 3223-3233
-
-
Akimov, V.1
Rigbolt, K.T.2
Nielsen, M.M.3
Blagoev, B.4
-
35
-
-
0033753057
-
Distribution of polyglutamylated tubulin in the flagellar apparatus of green flagellates
-
Lechtreck KF, Geimer S, (2000) Distribution of polyglutamylated tubulin in the flagellar apparatus of green flagellates. Cell Motil Cytoskeleton 47: 219-235.
-
(2000)
Cell Motil Cytoskeleton
, vol.47
, pp. 219-235
-
-
Lechtreck, K.F.1
Geimer, S.2
-
36
-
-
30544454640
-
The C. elegans homologs of nephrocystin-1 and nephrocystin-4 are cilia transition zone proteins involved in chemosensory perception
-
Winkelbauer ME, Schafer JC, Haycraft CJ, Swoboda P, Yoder BK, (2005) The C. elegans homologs of nephrocystin-1 and nephrocystin-4 are cilia transition zone proteins involved in chemosensory perception. J Cell Sci 118: 5575-5587.
-
(2005)
J Cell Sci
, vol.118
, pp. 5575-5587
-
-
Winkelbauer, M.E.1
Schafer, J.C.2
Haycraft, C.J.3
Swoboda, P.4
Yoder, B.K.5
-
37
-
-
79955808192
-
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways
-
Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, et al. (2011) Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell 145: 513-528.
-
(2011)
Cell
, vol.145
, pp. 513-528
-
-
Sang, L.1
Miller, J.J.2
Corbit, K.C.3
Giles, R.H.4
Brauer, M.J.5
-
38
-
-
84355161803
-
A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain
-
Chih B, Liu P, Chinn Y, Chalouni C, Komuves LG, et al. (2012) A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain. Nat Cell Biol 14: 61-72.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 61-72
-
-
Chih, B.1
Liu, P.2
Chinn, Y.3
Chalouni, C.4
Komuves, L.G.5
-
39
-
-
79960900387
-
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition
-
Garcia-Gonzalo FR, Corbit KC, Sirerol-Piquer MS, Ramaswami G, Otto EA, et al. (2011) A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition. Nat Genet 43: 776-784.
-
(2011)
Nat Genet
, vol.43
, pp. 776-784
-
-
Garcia-Gonzalo, F.R.1
Corbit, K.C.2
Sirerol-Piquer, M.S.3
Ramaswami, G.4
Otto, E.A.5
-
40
-
-
56049117628
-
CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium
-
Kim J, Krishnaswami SR, Gleeson JG, (2008) CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium. Hum Mol Genet 17: 3796-3805.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3796-3805
-
-
Kim, J.1
Krishnaswami, S.R.2
Gleeson, J.G.3
-
41
-
-
84878614972
-
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base
-
Wang WJ, Tay HG, Soni R, Perumal GS, Goll MG, et al. (2013) CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base. Nat Cell Biol 15: 591-601.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 591-601
-
-
Wang, W.J.1
Tay, H.G.2
Soni, R.3
Perumal, G.S.4
Goll, M.G.5
-
42
-
-
77956388187
-
CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content
-
Craige B, Tsao CC, Diener DR, Hou Y, Lechtreck KF, et al. (2010) CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content. J Cell Biol 190: 927-940.
-
(2010)
J Cell Biol
, vol.190
, pp. 927-940
-
-
Craige, B.1
Tsao, C.C.2
Diener, D.R.3
Hou, Y.4
Lechtreck, K.F.5
-
43
-
-
70350501513
-
Single molecule imaging reveals differences in microtubule track selection between Kinesin motors
-
Cai D, McEwen DP, Martens JR, Meyhofer E, Verhey KJ, (2009) Single molecule imaging reveals differences in microtubule track selection between Kinesin motors. PLoS Biol 7: e1000216.
-
(2009)
PLoS Biol
, vol.7
-
-
Cai, D.1
McEwen, D.P.2
Martens, J.R.3
Meyhofer, E.4
Verhey, K.J.5
-
44
-
-
80052511996
-
Roles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysis
-
Flores-Rodriguez N, Rogers SS, Kenwright DA, Waigh TA, Woodman PG, et al. (2011) Roles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysis. PLoS One 6: e24479.
-
(2011)
PLoS One
, vol.6
-
-
Flores-Rodriguez, N.1
Rogers, S.S.2
Kenwright, D.A.3
Waigh, T.A.4
Woodman, P.G.5
-
45
-
-
84856259713
-
Centrosome loss in the evolution of planarians
-
Azimzadeh J, Wong ML, Downhour DM, Sanchez Alvarado A, Marshall WF, (2012) Centrosome loss in the evolution of planarians. Science 335: 461-463.
-
(2012)
Science
, vol.335
, pp. 461-463
-
-
Azimzadeh, J.1
Wong, M.L.2
Downhour, D.M.3
Sanchez Alvarado, A.4
Marshall, W.F.5
-
46
-
-
79961049718
-
Rab11 function in Trypanosoma brucei: identification of conserved and novel interaction partners
-
Gabernet-Castello C, Dubois KN, Nimmo C, Field MC, (2011) Rab11 function in Trypanosoma brucei: identification of conserved and novel interaction partners. Eukaryot Cell 10: 1082-1094.
-
(2011)
Eukaryot Cell
, vol.10
, pp. 1082-1094
-
-
Gabernet-Castello, C.1
Dubois, K.N.2
Nimmo, C.3
Field, M.C.4
-
47
-
-
77958059452
-
Par6 alpha interacts with the dynactin subunit p150 Glued and is a critical regulator of centrosomal protein recruitment
-
Kodani A, Tonthat V, Wu B, Sutterlin C, (2010) Par6 alpha interacts with the dynactin subunit p150 Glued and is a critical regulator of centrosomal protein recruitment. Mol Biol Cell 21: 3376-3385.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 3376-3385
-
-
Kodani, A.1
Tonthat, V.2
Wu, B.3
Sutterlin, C.4
-
48
-
-
1942502194
-
Cell biology of normal and abnormal ciliogenesis in the ciliated epithelium
-
Hagiwara H, Ohwada N, Takata K, (2004) Cell biology of normal and abnormal ciliogenesis in the ciliated epithelium. Int Rev Cytol 234: 101-141.
-
(2004)
Int Rev Cytol
, vol.234
, pp. 101-141
-
-
Hagiwara, H.1
Ohwada, N.2
Takata, K.3
-
49
-
-
0026051642
-
Centriole and basal body formation during ciliogenesis revisited
-
Dirksen ER, (1991) Centriole and basal body formation during ciliogenesis revisited. Biol Cell 72: 31-38.
-
(1991)
Biol Cell
, vol.72
, pp. 31-38
-
-
Dirksen, E.R.1
-
50
-
-
84860378636
-
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity
-
Freudenberg JM, Ghosh S, Lackford BL, Yellaboina S, Zheng X, et al. (2012) Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity. Nucleic Acids Res 40: 3364-3377.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 3364-3377
-
-
Freudenberg, J.M.1
Ghosh, S.2
Lackford, B.L.3
Yellaboina, S.4
Zheng, X.5
-
51
-
-
78049310300
-
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline
-
Pulvers JN, Bryk J, Fish JL, Wilsch-Brauninger M, Arai Y, et al. (2010) Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline. Proc Natl Acad Sci U S A 107: 16595-16600.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 16595-16600
-
-
Pulvers, J.N.1
Bryk, J.2
Fish, J.L.3
Wilsch-Brauninger, M.4
Arai, Y.5
-
52
-
-
84864584531
-
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling
-
Chaki M, Airik R, Ghosh AK, Giles RH, Chen R, et al. (2012) Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell 150: 533-548.
-
(2012)
Cell
, vol.150
, pp. 533-548
-
-
Chaki, M.1
Airik, R.2
Ghosh, A.K.3
Giles, R.H.4
Chen, R.5
-
53
-
-
1542609301
-
Forward genetic screens for meiotic and mitotic recombination-defective mutants in mice
-
Reinholdt L, Ashley T, Schimenti J, Shima N, (2004) Forward genetic screens for meiotic and mitotic recombination-defective mutants in mice. Methods Mol Biol 262: 87-107.
-
(2004)
Methods Mol Biol
, vol.262
, pp. 87-107
-
-
Reinholdt, L.1
Ashley, T.2
Schimenti, J.3
Shima, N.4
-
54
-
-
76749170775
-
BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice
-
Liang Y, Gao H, Lin SY, Peng G, Huang X, et al. (2010) BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice. PLoS Genet 6: e1000826.
-
(2010)
PLoS Genet
, vol.6
-
-
Liang, Y.1
Gao, H.2
Lin, S.Y.3
Peng, G.4
Huang, X.5
-
55
-
-
20944445215
-
Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome
-
Fath MA, Mullins RF, Searby C, Nishimura DY, Wei J, et al. (2005) Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome. Hum Mol Genet 14: 1109-1118.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1109-1118
-
-
Fath, M.A.1
Mullins, R.F.2
Searby, C.3
Nishimura, D.Y.4
Wei, J.5
-
56
-
-
2942625562
-
Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly
-
Mykytyn K, Mullins RF, Andrews M, Chiang AP, Swiderski RE, et al. (2004) Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly. Proc Natl Acad Sci U S A 101: 8664-8669.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8664-8669
-
-
Mykytyn, K.1
Mullins, R.F.2
Andrews, M.3
Chiang, A.P.4
Swiderski, R.E.5
-
57
-
-
9344261783
-
Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin
-
Nishimura DY, Fath M, Mullins RF, Searby C, Andrews M, et al. (2004) Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin. Proc Natl Acad Sci U S A 101: 16588-16593.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 16588-16593
-
-
Nishimura, D.Y.1
Fath, M.2
Mullins, R.F.3
Searby, C.4
Andrews, M.5
-
58
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, et al. (2002) Genomic instability in mice lacking histone H2AX. Science 296: 922-927.
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
-
59
-
-
34249885603
-
Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss
-
Ruzankina Y, Pinzon-Guzman C, Asare A, Ong T, Pontano L, et al. (2007) Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. Cell Stem Cell 1: 113-126.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 113-126
-
-
Ruzankina, Y.1
Pinzon-Guzman, C.2
Asare, A.3
Ong, T.4
Pontano, L.5
-
60
-
-
0038296998
-
Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice
-
Xu X, Aprelikova O, Moens P, Deng CX, Furth PA, (2003) Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice. Development 130: 2001-2012.
-
(2003)
Development
, vol.130
, pp. 2001-2012
-
-
Xu, X.1
Aprelikova, O.2
Moens, P.3
Deng, C.X.4
Furth, P.A.5
-
61
-
-
54449093278
-
Targeted disruption of Nphp1 causes male infertility due to defects in the later steps of sperm morphogenesis in mice
-
Jiang ST, Chiou YY, Wang E, Lin HK, Lee SP, et al. (2008) Targeted disruption of Nphp1 causes male infertility due to defects in the later steps of sperm morphogenesis in mice. Hum Mol Genet 17: 3368-3379.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3368-3379
-
-
Jiang, S.T.1
Chiou, Y.Y.2
Wang, E.3
Lin, H.K.4
Lee, S.P.5
-
62
-
-
78651078413
-
NPHP4 is necessary for normal photoreceptor ribbon synapse maintenance and outer segment formation, and for sperm development
-
Won J, Marin de Evsikova C, Smith RS, Hicks WL, Edwards MM, et al. (2011) NPHP4 is necessary for normal photoreceptor ribbon synapse maintenance and outer segment formation, and for sperm development. Hum Mol Genet 20: 482-496.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 482-496
-
-
Won, J.1
Marin de Evsikova, C.2
Smith, R.S.3
Hicks, W.L.4
Edwards, M.M.5
-
63
-
-
0036544554
-
The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance
-
Pazour GJ, Baker SA, Deane JA, Cole DG, Dickert BL, et al. (2002) The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance. J Cell Biol 157: 103-113.
-
(2002)
J Cell Biol
, vol.157
, pp. 103-113
-
-
Pazour, G.J.1
Baker, S.A.2
Deane, J.A.3
Cole, D.G.4
Dickert, B.L.5
-
64
-
-
0141706698
-
IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia
-
Baker SA, Freeman K, Luby-Phelps K, Pazour GJ, Besharse JC, (2003) IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia. J Biol Chem 278: 34211-34218.
-
(2003)
J Biol Chem
, vol.278
, pp. 34211-34218
-
-
Baker, S.A.1
Freeman, K.2
Luby-Phelps, K.3
Pazour, G.J.4
Besharse, J.C.5
-
65
-
-
84868108255
-
RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly
-
Lo JC, Jamsai D, O'Connor AE, Borg C, Clark BJ, et al. (2012) RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet 8: e1002969.
-
(2012)
PLoS Genet
, vol.8
-
-
Lo, J.C.1
Jamsai, D.2
O'Connor, A.E.3
Borg, C.4
Clark, B.J.5
-
66
-
-
1642422832
-
Formation and organization of the mammalian sperm head
-
Toshimori K, Ito C, (2003) Formation and organization of the mammalian sperm head. Arch Histol Cytol 66: 383-396.
-
(2003)
Arch Histol Cytol
, vol.66
, pp. 383-396
-
-
Toshimori, K.1
Ito, C.2
-
67
-
-
0036021241
-
Intramanchette transport (IMT): managing the making of the spermatid head, centrosome, and tail
-
Kierszenbaum AL, (2002) Intramanchette transport (IMT): managing the making of the spermatid head, centrosome, and tail. Mol Reprod Dev 63: 1-4.
-
(2002)
Mol Reprod Dev
, vol.63
, pp. 1-4
-
-
Kierszenbaum, A.L.1
-
68
-
-
0025246395
-
Abnormal manchette development in spermatids of azh/azh mutant mice
-
Meistrich ML, Trostle-Weige PK, Russell LD, (1990) Abnormal manchette development in spermatids of azh/azh mutant mice. Am J Anat 188: 74-86.
-
(1990)
Am J Anat
, vol.188
, pp. 74-86
-
-
Meistrich, M.L.1
Trostle-Weige, P.K.2
Russell, L.D.3
-
69
-
-
0023969209
-
Nuclear and manchette development in spermatids of normal and azh/azh mutant mice
-
Cole A, Meistrich ML, Cherry LM, Trostle-Weige PK, (1988) Nuclear and manchette development in spermatids of normal and azh/azh mutant mice. Biol Reprod 38: 385-401.
-
(1988)
Biol Reprod
, vol.38
, pp. 385-401
-
-
Cole, A.1
Meistrich, M.L.2
Cherry, L.M.3
Trostle-Weige, P.K.4
-
70
-
-
64549137673
-
RIM-BP3 is a manchette-associated protein essential for spermiogenesis
-
Zhou J, Du YR, Qin WH, Hu YG, Huang YN, et al. (2009) RIM-BP3 is a manchette-associated protein essential for spermiogenesis. Development 136: 373-382.
-
(2009)
Development
, vol.136
, pp. 373-382
-
-
Zhou, J.1
Du, Y.R.2
Qin, W.H.3
Hu, Y.G.4
Huang, Y.N.5
-
71
-
-
0014594757
-
The fine structure and development of the neck region of the mammalian spermatozoon
-
Fawcett DW, Phillips DM, (1969) The fine structure and development of the neck region of the mammalian spermatozoon. Anat Rec 165: 153-164.
-
(1969)
Anat Rec
, vol.165
, pp. 153-164
-
-
Fawcett, D.W.1
Phillips, D.M.2
-
72
-
-
0032792930
-
Acephalic spermatozoa and abnormal development of the head-neck attachment: a human syndrome of genetic origin
-
Chemes HE, Puigdomenech ET, Carizza C, Olmedo SB, Zanchetti F, et al. (1999) Acephalic spermatozoa and abnormal development of the head-neck attachment: a human syndrome of genetic origin. Hum Reprod 14: 1811-1818.
-
(1999)
Hum Reprod
, vol.14
, pp. 1811-1818
-
-
Chemes, H.E.1
Puigdomenech, E.T.2
Carizza, C.3
Olmedo, S.B.4
Zanchetti, F.5
-
73
-
-
0036647024
-
The Hook1 gene is non-functional in the abnormal spermatozoon head shape (azh) mutant mouse
-
Mendoza-Lujambio I, Burfeind P, Dixkens C, Meinhardt A, Hoyer-Fender S, et al. (2002) The Hook1 gene is non-functional in the abnormal spermatozoon head shape (azh) mutant mouse. Hum Mol Genet 11: 1647-1658.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1647-1658
-
-
Mendoza-Lujambio, I.1
Burfeind, P.2
Dixkens, C.3
Meinhardt, A.4
Hoyer-Fender, S.5
-
74
-
-
84864311301
-
Cytoskeletal track selection during cargo transport in spermatids is relevant to male fertility
-
Kierszenbaum AL, Rivkin E, Tres LL, (2011) Cytoskeletal track selection during cargo transport in spermatids is relevant to male fertility. Spermatogenesis 1: 221-230.
-
(2011)
Spermatogenesis
, vol.1
, pp. 221-230
-
-
Kierszenbaum, A.L.1
Rivkin, E.2
Tres, L.L.3
-
75
-
-
0026013995
-
Differential post-translational modifications of microtubules in cells of the seminiferous epithelium of the rat: a light and electron microscope immunocytochemical study
-
Hermo L, Oko R, Hecht NB, (1991) Differential post-translational modifications of microtubules in cells of the seminiferous epithelium of the rat: a light and electron microscope immunocytochemical study. Anat Rec 229: 31-50.
-
(1991)
Anat Rec
, vol.229
, pp. 31-50
-
-
Hermo, L.1
Oko, R.2
Hecht, N.B.3
-
76
-
-
79951603511
-
GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail
-
Kierszenbaum AL, Rivkin E, Tres LL, Yoder BK, Haycraft CJ, et al. (2011) GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail. Dev Dyn 240: 723-736.
-
(2011)
Dev Dyn
, vol.240
, pp. 723-736
-
-
Kierszenbaum, A.L.1
Rivkin, E.2
Tres, L.L.3
Yoder, B.K.4
Haycraft, C.J.5
-
77
-
-
4444254983
-
Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse
-
Kulaga HM, Leitch CC, Eichers ER, Badano JL, Lesemann A, et al. (2004) Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse. Nat Genet 36: 994-998.
-
(2004)
Nat Genet
, vol.36
, pp. 994-998
-
-
Kulaga, H.M.1
Leitch, C.C.2
Eichers, E.R.3
Badano, J.L.4
Lesemann, A.5
-
78
-
-
0034069115
-
ARP1 in Golgi organisation and attachment of manchette microtubules to the nucleus during mammalian spermatogenesis
-
Fouquet J, Kann M, Soues S, Melki R, (2000) ARP1 in Golgi organisation and attachment of manchette microtubules to the nucleus during mammalian spermatogenesis. J Cell Sci 113 (Pt 5) (): 877-886.
-
(2000)
J Cell Sci
, vol.113
, Issue.Pt 5
, pp. 877-886
-
-
Fouquet, J.1
Kann, M.2
Soues, S.3
Melki, R.4
-
79
-
-
33744757686
-
In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse
-
Chang B, Khanna H, Hawes N, Jimeno D, He S, et al. (2006) In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse. Hum Mol Genet 15: 1847-1857.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1847-1857
-
-
Chang, B.1
Khanna, H.2
Hawes, N.3
Jimeno, D.4
He, S.5
-
80
-
-
79958121228
-
Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome
-
Lancaster MA, Gopal DJ, Kim J, Saleem SN, Silhavy JL, et al. (2011) Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome. Nat Med 17: 726-731.
-
(2011)
Nat Med
, vol.17
, pp. 726-731
-
-
Lancaster, M.A.1
Gopal, D.J.2
Kim, J.3
Saleem, S.N.4
Silhavy, J.L.5
-
81
-
-
0030868540
-
A novel gene encoding an SH3 domain protein is mutated in nephronophthisis type 1
-
Hildebrandt F, Otto E, Rensing C, Nothwang HG, Vollmer M, et al. (1997) A novel gene encoding an SH3 domain protein is mutated in nephronophthisis type 1. Nat Genet 17: 149-153.
-
(1997)
Nat Genet
, vol.17
, pp. 149-153
-
-
Hildebrandt, F.1
Otto, E.2
Rensing, C.3
Nothwang, H.G.4
Vollmer, M.5
-
82
-
-
1842579395
-
The oligogenic properties of Bardet-Biedl syndrome
-
Katsanis N, (2004) The oligogenic properties of Bardet-Biedl syndrome. Hum Mol Genet 13 Spec No 1: R65-71.
-
(2004)
Hum Mol Genet
, vol.13
, Issue.SPEC. 1
-
-
Katsanis, N.1
-
83
-
-
0035929273
-
Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder
-
Katsanis N, Ansley SJ, Badano JL, Eichers ER, Lewis RA, et al. (2001) Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder. Science 293: 2256-2259.
-
(2001)
Science
, vol.293
, pp. 2256-2259
-
-
Katsanis, N.1
Ansley, S.J.2
Badano, J.L.3
Eichers, E.R.4
Lewis, R.A.5
-
84
-
-
84866675239
-
Investigating embryonic expression patterns and evolution of AHI1 and CEP290 genes, implicated in Joubert syndrome
-
Cheng YZ, Eley L, Hynes AM, Overman LM, Simms RJ, et al. (2012) Investigating embryonic expression patterns and evolution of AHI1 and CEP290 genes, implicated in Joubert syndrome. PLoS One 7: e44975.
-
(2012)
PLoS One
, vol.7
-
-
Cheng, Y.Z.1
Eley, L.2
Hynes, A.M.3
Overman, L.M.4
Simms, R.J.5
-
85
-
-
33645450571
-
Gravitaxis in Drosophila melanogaster: a forward genetic screen
-
Armstrong JD, Texada MJ, Munjaal R, Baker DA, Beckingham KM, (2006) Gravitaxis in Drosophila melanogaster: a forward genetic screen. Genes Brain Behav 5: 222-239.
-
(2006)
Genes Brain Behav
, vol.5
, pp. 222-239
-
-
Armstrong, J.D.1
Texada, M.J.2
Munjaal, R.3
Baker, D.A.4
Beckingham, K.M.5
-
86
-
-
46749154718
-
Yuri gagarin is required for actin, tubulin and basal body functions in Drosophila spermatogenesis
-
Texada MJ, Simonette RA, Johnson CB, Deery WJ, Beckingham KM, (2008) Yuri gagarin is required for actin, tubulin and basal body functions in Drosophila spermatogenesis. J Cell Sci 121: 1926-1936.
-
(2008)
J Cell Sci
, vol.121
, pp. 1926-1936
-
-
Texada, M.J.1
Simonette, R.A.2
Johnson, C.B.3
Deery, W.J.4
Beckingham, K.M.5
-
87
-
-
4243123143
-
Mechanosensory-defective, male-sterile unc mutants identify a novel basal body protein required for ciliogenesis in Drosophila
-
Baker JD, Adhikarakunnathu S, Kernan MJ, (2004) Mechanosensory-defective, male-sterile unc mutants identify a novel basal body protein required for ciliogenesis in Drosophila. Development 131: 3411-3422.
-
(2004)
Development
, vol.131
, pp. 3411-3422
-
-
Baker, J.D.1
Adhikarakunnathu, S.2
Kernan, M.J.3
-
88
-
-
11944258521
-
Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis
-
Kotaja N, Kimmins S, Brancorsini S, Hentsch D, Vonesch JL, et al. (2004) Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis. Nat Methods 1: 249-254.
-
(2004)
Nat Methods
, vol.1
, pp. 249-254
-
-
Kotaja, N.1
Kimmins, S.2
Brancorsini, S.3
Hentsch, D.4
Vonesch, J.L.5
-
89
-
-
75449114021
-
Detection of CFTR transgene mRNA expression in respiratory epithelium isolated from the murine nasal cavity
-
Holder E, Stevenson B, Farley R, Hilliard T, Wodehouse T, et al. (2010) Detection of CFTR transgene mRNA expression in respiratory epithelium isolated from the murine nasal cavity. J Gene Med 12: 55-63.
-
(2010)
J Gene Med
, vol.12
, pp. 55-63
-
-
Holder, E.1
Stevenson, B.2
Farley, R.3
Hilliard, T.4
Wodehouse, T.5
-
90
-
-
0037306756
-
DNA double-strand breaks and gamma-H2AX signaling in the testis
-
Hamer G, Roepers-Gajadien HL, van Duyn-Goedhart A, Gademan IS, Kal HB, et al. (2003) DNA double-strand breaks and gamma-H2AX signaling in the testis. Biol Reprod 68: 628-634.
-
(2003)
Biol Reprod
, vol.68
, pp. 628-634
-
-
Hamer, G.1
Roepers-Gajadien, H.L.2
van Duyn-Goedhart, A.3
Gademan, I.S.4
Kal, H.B.5
|