-
1
-
-
34748885788
-
Two T-box genes play independent and cooperative roles to regulate morphogenesis of ciliated Kupffer's vesicle in zebrafish
-
Amack J.D., Wang X., Yost H.J. Two T-box genes play independent and cooperative roles to regulate morphogenesis of ciliated Kupffer's vesicle in zebrafish. Dev. Biol. 2007, 310:196-210.
-
(2007)
Dev. Biol.
, vol.310
, pp. 196-210
-
-
Amack, J.D.1
Wang, X.2
Yost, H.J.3
-
3
-
-
77950505396
-
Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia
-
Borovina A., Superina S., Voskas D., Ciruna B. Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia. Nat. Cell Biol. 2010, 12:407-412.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 407-412
-
-
Borovina, A.1
Superina, S.2
Voskas, D.3
Ciruna, B.4
-
4
-
-
70449627625
-
Ciliary biology: understanding the cellular and genetic basis of human ciliopathies
-
Cardenas-Rodriguez M., Badano J.L. Ciliary biology: understanding the cellular and genetic basis of human ciliopathies. Am. J. Med. Genet. C Semin. Med. Genet. 2009, 151C:263-280.
-
(2009)
Am. J. Med. Genet. C Semin. Med. Genet.
, vol.151 C
, pp. 263-280
-
-
Cardenas-Rodriguez, M.1
Badano, J.L.2
-
5
-
-
26644460824
-
Vertebrate smoothened functions at the primary cilium
-
Corbit K.C., Aanstad P., Singla V., Norman A.R., Stainier D.Y., Reiter J.F. Vertebrate smoothened functions at the primary cilium. Nature 2005, 437:1018-1021.
-
(2005)
Nature
, vol.437
, pp. 1018-1021
-
-
Corbit, K.C.1
Aanstad, P.2
Singla, V.3
Norman, A.R.4
Stainier, D.Y.5
Reiter, J.F.6
-
6
-
-
37749054886
-
Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms
-
Corbit K.C., Shyer A.E., Dowdle W.E., Gaulden J., Singla V., Chen M.H., Chuang P.T., Reiter J.F. Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms. Nat. Cell Biol. 2008, 10:70-76.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 70-76
-
-
Corbit, K.C.1
Shyer, A.E.2
Dowdle, W.E.3
Gaulden, J.4
Singla, V.5
Chen, M.H.6
Chuang, P.T.7
Reiter, J.F.8
-
7
-
-
70450176073
-
Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion
-
Duldulao N.A., Lee S., Sun Z. Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion. Development 2009, 136:4033-4042.
-
(2009)
Development
, vol.136
, pp. 4033-4042
-
-
Duldulao, N.A.1
Lee, S.2
Sun, Z.3
-
8
-
-
35648985644
-
Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
-
Gerdes J.M., Liu Y., Zaghloul N.A., Leitch C.C., Lawson S.S., Kato M., Beachy P.A., Beales P.L., DeMartino G.N., Fisher S., et al. Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response. Nat. Genet. 2007, 39:1350-1360.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1350-1360
-
-
Gerdes, J.M.1
Liu, Y.2
Zaghloul, N.A.3
Leitch, C.C.4
Lawson, S.S.5
Kato, M.6
Beachy, P.A.7
Beales, P.L.8
DeMartino, G.N.9
Fisher, S.10
-
9
-
-
77953662946
-
The primary cilium as a Hedgehog signal transduction machine
-
Goetz S.C., Ocbina P.J., Anderson K.V. The primary cilium as a Hedgehog signal transduction machine. Methods Cell Biol. 2009, 94:199-222.
-
(2009)
Methods Cell Biol.
, vol.94
, pp. 199-222
-
-
Goetz, S.C.1
Ocbina, P.J.2
Anderson, K.V.3
-
10
-
-
55249102622
-
CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290
-
Gorden N.T., Arts H.H., Parisi M.A., Coene K.L., Letteboer S.J., van Beersum S.E., Mans D.A., Hikida A., Eckert M., Knutzen D., et al. CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290. Am. J. Hum. Genet. 2008, 83:559-571.
-
(2008)
Am. J. Hum. Genet.
, vol.83
, pp. 559-571
-
-
Gorden, N.T.1
Arts, H.H.2
Parisi, M.A.3
Coene, K.L.4
Letteboer, S.J.5
van Beersum, S.E.6
Mans, D.A.7
Hikida, A.8
Eckert, M.9
Knutzen, D.10
-
11
-
-
70349986352
-
Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia
-
Huang P., Schier A.F. Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development 2009, 136:3089-3098.
-
(2009)
Development
, vol.136
, pp. 3089-3098
-
-
Huang, P.1
Schier, A.F.2
-
12
-
-
0242581681
-
Hedgehog signalling in the mouse requires intraflagellar transport proteins
-
Huangfu D., Liu A., Rakeman A.S., Murcia N.S., Niswander L., Anderson K.V. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 2003, 426:83-87.
-
(2003)
Nature
, vol.426
, pp. 83-87
-
-
Huangfu, D.1
Liu, A.2
Rakeman, A.S.3
Murcia, N.S.4
Niswander, L.5
Anderson, K.V.6
-
13
-
-
77955621502
-
Imaging cilia in zebrafish
-
Jaffe K.M., Thiberge S.Y., Bisher M.E., Burdine R.D. Imaging cilia in zebrafish. Methods Cell Biol. 2010, 97:415-435.
-
(2010)
Methods Cell Biol.
, vol.97
, pp. 415-435
-
-
Jaffe, K.M.1
Thiberge, S.Y.2
Bisher, M.E.3
Burdine, R.D.4
-
14
-
-
77953879123
-
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia
-
Jin H., White S.R., Shida T., Schulz S., Aguiar M., Gygi S.P., Bazan J.F., Nachury M.V. The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia. Cell 2010, 141:1208-1219.
-
(2010)
Cell
, vol.141
, pp. 1208-1219
-
-
Jin, H.1
White, S.R.2
Shida, T.3
Schulz, S.4
Aguiar, M.5
Gygi, S.P.6
Bazan, J.F.7
Nachury, M.V.8
-
15
-
-
71149086940
-
Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects
-
Loges N.T., Olbrich H., Becker-Heck A., Häffner K., Heer A., Reinhard C., Schmidts M., Kispert A., Zariwala M.A., Leigh M.W., Knowles M.R., Zentgraf H., Seithe H., Nurnberg G., Nunberg P., Reinhardt R., Omran H. Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects. Am. J. Hum. Genet. 2009, 85:883-889.
-
(2009)
Am. J. Hum. Genet.
, vol.85
, pp. 883-889
-
-
Loges, N.T.1
Olbrich, H.2
Becker-Heck, A.3
Häffner, K.4
Heer, A.5
Reinhard, C.6
Schmidts, M.7
Kispert, A.8
Zariwala, M.A.9
Leigh, M.W.10
Knowles, M.R.11
Zentgraf, H.12
Seithe, H.13
Nurnberg, G.14
Nunberg, P.15
Reinhardt, R.16
Omran, H.17
-
16
-
-
79953331186
-
Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry
-
Kim S., Zaghloul N.A., Bubenshchikova E., Oh E.C., Rankin S., Katsanis N., Obara T., Tsiokas L. Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry. Nat. Cell Biol. 2011, 13(4):351-360.
-
(2011)
Nat. Cell Biol.
, vol.13
, Issue.4
, pp. 351-360
-
-
Kim, S.1
Zaghloul, N.A.2
Bubenshchikova, E.3
Oh, E.C.4
Rankin, S.5
Katsanis, N.6
Obara, T.7
Tsiokas, L.8
-
17
-
-
44449141342
-
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways
-
Kishimoto N., Cao Y., Park A., Sun Z. Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways. Dev. Cell 2008, 14:954-961.
-
(2008)
Dev. Cell
, vol.14
, pp. 954-961
-
-
Kishimoto, N.1
Cao, Y.2
Park, A.3
Sun, Z.4
-
18
-
-
46749083885
-
The intraflagellar transport protein IFT57 is required for cilia maintenance and regulates IFT-particle-kinesin-II dissociation in vertebrate photoreceptors
-
Krock B.L., Perkins B.D. The intraflagellar transport protein IFT57 is required for cilia maintenance and regulates IFT-particle-kinesin-II dissociation in vertebrate photoreceptors. J. Cell Sci. 2008, 121:1907-1915.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 1907-1915
-
-
Krock, B.L.1
Perkins, B.D.2
-
19
-
-
41349103272
-
Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome
-
Leitch C.C., Zaghloul N.A., Davis E.E., Stoetzel C., Diaz-Font A., Rix S., Alfadhel M., Lewis R.A., Eyaid W., Banin E., et al. Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome. Nat. Genet. 2008, 40:443-448.
-
(2008)
Nat. Genet.
, vol.40
, pp. 443-448
-
-
Leitch, C.C.1
Zaghloul, N.A.2
Davis, E.E.3
Stoetzel, C.4
Diaz-Font, A.5
Rix, S.6
Alfadhel, M.7
Lewis, R.A.8
Eyaid, W.9
Banin, E.10
-
20
-
-
67649588270
-
Zebrafish ift57, ift88, and ift172 intraflagellar transport mutants disrupt cilia but do not affect hedgehog signaling
-
Lunt S.C., Haynes T., Perkins B.D. Zebrafish ift57, ift88, and ift172 intraflagellar transport mutants disrupt cilia but do not affect hedgehog signaling. Dev. Dyn. 2009, 238:1744-1759.
-
(2009)
Dev. Dyn.
, vol.238
, pp. 1744-1759
-
-
Lunt, S.C.1
Haynes, T.2
Perkins, B.D.3
-
21
-
-
12644295051
-
Mutations affecting development of the zebrafish retina
-
Malicki J., Neuhauss S.C., Schier A.F., Solnica-Krezel L., Stemple D.L., Stainier D.Y., Abdelilah S., Zwartkruis F., Rangini Z., Driever W. Mutations affecting development of the zebrafish retina. Development 1996, 123:263-273.
-
(1996)
Development
, vol.123
, pp. 263-273
-
-
Malicki, J.1
Neuhauss, S.C.2
Schier, A.F.3
Solnica-Krezel, L.4
Stemple, D.L.5
Stainier, D.Y.6
Abdelilah, S.7
Zwartkruis, F.8
Rangini, Z.9
Driever, W.10
-
22
-
-
33749268369
-
Polycystin-2 immunolocalization and function in zebrafish
-
Obara T., Mangos S., Liu Y., Zhao J., Wiessner S., Kramer-Zucker A.G., Olale F., Schier A.F., Drummond I.A. Polycystin-2 immunolocalization and function in zebrafish. J. Am. Soc. Nephrol. 2006, 17:2706-2718.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 2706-2718
-
-
Obara, T.1
Mangos, S.2
Liu, Y.3
Zhao, J.4
Wiessner, S.5
Kramer-Zucker, A.G.6
Olale, F.7
Schier, A.F.8
Drummond, I.A.9
-
23
-
-
43149102968
-
Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8
-
Omori Y., Zhao C., Saras A., Mukhopadhyay S., Kim W., Furukawa T., Sengupta P., Veraksa A., Malicki J. Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8. Nat. Cell Biol. 2008, 10:437-444.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 437-444
-
-
Omori, Y.1
Zhao, C.2
Saras, A.3
Mukhopadhyay, S.4
Kim, W.5
Furukawa, T.6
Sengupta, P.7
Veraksa, A.8
Malicki, J.9
-
25
-
-
40149095948
-
Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death
-
Owens K.N., Santos F., Roberts B., Linbo T., Coffin A.B., Knisely A.J., Simon J.A., Rubel E.W., Raible D.W. Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death. PLoS Genet. 2008, 4:e1000020.
-
(2008)
PLoS Genet.
, vol.4
-
-
Owens, K.N.1
Santos, F.2
Roberts, B.3
Linbo, T.4
Coffin, A.B.5
Knisely, A.J.6
Simon, J.A.7
Rubel, E.W.8
Raible, D.W.9
-
26
-
-
35848952293
-
The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation
-
Pathak N., Obara T., Mangos S., Liu Y., Drummond I.A. The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation. Mol. Biol. Cell 2007, 18:4353-4364.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 4353-4364
-
-
Pathak, N.1
Obara, T.2
Mangos, S.3
Liu, Y.4
Drummond, I.A.5
-
27
-
-
58149326846
-
Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling
-
Pedersen L.B., Rosenbaum J.L. Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling. Curr. Top. Dev. Biol. 2008, 85:23-61.
-
(2008)
Curr. Top. Dev. Biol.
, vol.85
, pp. 23-61
-
-
Pedersen, L.B.1
Rosenbaum, J.L.2
-
28
-
-
27144460671
-
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
-
Ross A.J., May-Simera H., Eichers E.R., Kai M., Hill J., Jagger D.J., Leitch C.C., Chapple J.P., Munro P.M., Fisher S., et al. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat. Genet. 2005, 37:1135-1140.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1135-1140
-
-
Ross, A.J.1
May-Simera, H.2
Eichers, E.R.3
Kai, M.4
Hill, J.5
Jagger, D.J.6
Leitch, C.C.7
Chapple, J.P.8
Munro, P.M.9
Fisher, S.10
-
30
-
-
34248597580
-
Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw
-
Schottenfeld J., Sullivan-Brown J., Burdine R.D. Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw. Development 2007, 134:1605-1615.
-
(2007)
Development
, vol.134
, pp. 1605-1615
-
-
Schottenfeld, J.1
Sullivan-Brown, J.2
Burdine, R.D.3
-
31
-
-
0033809423
-
Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension
-
Sepich D.S., Myers D.C., Short R., Topczewski J., Marlow F., Solnica-Krezel L. Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension. Genesis 2000, 27:159-173.
-
(2000)
Genesis
, vol.27
, pp. 159-173
-
-
Sepich, D.S.1
Myers, D.C.2
Short, R.3
Topczewski, J.4
Marlow, F.5
Solnica-Krezel, L.6
-
32
-
-
78751549940
-
Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements
-
Sepich D.S., Usmani M., Pawlicki S., Solnica-Krezel L. Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements. Development 2011, 138:543-552.
-
(2011)
Development
, vol.138
, pp. 543-552
-
-
Sepich, D.S.1
Usmani, M.2
Pawlicki, S.3
Solnica-Krezel, L.4
-
33
-
-
68549133606
-
Mutations in zebrafish leucine-rich repeat-containing six-like affect cilia motility and result in pronephric cysts, but have variable effects on left-right patterning
-
Serluca F.C., Xu B., Okabe N., Baker K., Lin S.Y., Sullivan-Brown J., Konieczkowski D.J., Jaffe K.M., Bradner J.M., Fishman M.C., et al. Mutations in zebrafish leucine-rich repeat-containing six-like affect cilia motility and result in pronephric cysts, but have variable effects on left-right patterning. Development 2009, 136:1621-1631.
-
(2009)
Development
, vol.136
, pp. 1621-1631
-
-
Serluca, F.C.1
Xu, B.2
Okabe, N.3
Baker, K.4
Lin, S.Y.5
Sullivan-Brown, J.6
Konieczkowski, D.J.7
Jaffe, K.M.8
Bradner, J.M.9
Fishman, M.C.10
-
34
-
-
60349111593
-
Early defects in photoreceptor outer segment morphogenesis in zebrafish ift57, ift88 and ift172 intraflagellar transport mutants
-
Sukumaran S., Perkins B.D. Early defects in photoreceptor outer segment morphogenesis in zebrafish ift57, ift88 and ift172 intraflagellar transport mutants. Vision Res. 2009, 49:479-489.
-
(2009)
Vision Res.
, vol.49
, pp. 479-489
-
-
Sukumaran, S.1
Perkins, B.D.2
-
35
-
-
39149144464
-
Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants
-
Sullivan-Brown J., Schottenfeld J., Okabe N., Hostetter C.L., Serluca F.C., Thiberge S.Y., Burdine R.D. Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants. Dev. Biol. 2008, 314:261-275.
-
(2008)
Dev. Biol.
, vol.314
, pp. 261-275
-
-
Sullivan-Brown, J.1
Schottenfeld, J.2
Okabe, N.3
Hostetter, C.L.4
Serluca, F.C.5
Thiberge, S.Y.6
Burdine, R.D.7
-
36
-
-
4544383179
-
A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney
-
Sun Z., Amsterdam A., Pazour G.J., Cole D.G., Miller M.S., Hopkins N. A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney. Development 2004, 131:4085-4093.
-
(2004)
Development
, vol.131
, pp. 4085-4093
-
-
Sun, Z.1
Amsterdam, A.2
Pazour, G.J.3
Cole, D.G.4
Miller, M.S.5
Hopkins, N.6
-
37
-
-
38149126474
-
High-resolution in situ hybridization to whole-mount zebrafish embryos
-
Thisse C., Thisse B. High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat. Protoc. 2008, 3:59-69.
-
(2008)
Nat. Protoc.
, vol.3
, pp. 59-69
-
-
Thisse, C.1
Thisse, B.2
-
38
-
-
2942596578
-
Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons
-
Tsujikawa M., Malicki J. Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons. Neuron 2004, 42:703-716.
-
(2004)
Neuron
, vol.42
, pp. 703-716
-
-
Tsujikawa, M.1
Malicki, J.2
-
39
-
-
48049086579
-
LRRC50, a conserved ciliary protein implicated in polycystic kidney disease
-
van Rooijen E., Giles R.H., Voest E.E., van Rooijen C., Schulte-Merker S., van Eeden F.J. LRRC50, a conserved ciliary protein implicated in polycystic kidney disease. J. Am. Soc. Nephrol. 2008, 19:1128-1138.
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 1128-1138
-
-
van Rooijen, E.1
Giles, R.H.2
Voest, E.E.3
van Rooijen, C.4
Schulte-Merker, S.5
van Eeden, F.J.6
-
41
-
-
77953730407
-
Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome
-
Zaghloul N.A., Liu Y., Gerdes J.M., Gascue C., Oh E.C., Leitch C.C., Bromberg Y., Binkley J., Leibel R.L., Sidow A., et al. Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:10602-10607.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 10602-10607
-
-
Zaghloul, N.A.1
Liu, Y.2
Gerdes, J.M.3
Gascue, C.4
Oh, E.C.5
Leitch, C.C.6
Bromberg, Y.7
Binkley, J.8
Leibel, R.L.9
Sidow, A.10
|