Rapid disorganization of mechanically interacting systems of mammary acini

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 2, 2014, Pages 658-663

  Shi, Quanming ^a   Ghosh, Rajarshi P ^a   Engelke, Hanna ^a   Rycroft, Chris H ^a,b   Cassereau, Luke ^a,c   Sethian, James A ^a,b   Weaver, Valerie M ^a,c   Liphardt, Jan T ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cancer; Mechanobiology

Indexed keywords

COLLAGEN; RAS PROTEIN;

ACINAR CELL; ARTICLE; BIOMECHANICS; BREAST CELL; CELL DIFFERENTIATION; CELL INTERACTION; CELL INVASION; CELL STRUCTURE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; LASER; PHENOTYPE; PRIORITY JOURNAL;

CANCER; MECHANOBIOLOGY;

ACINAR CELLS; BREAST NEOPLASMS; CELL COMMUNICATION; CELL LINE, TUMOR; CELL SEPARATION; COLLAGEN; ESCHERICHIA COLI; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MAMMARY GLANDS, HUMAN; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE;

EID: 84892578009     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1311312110     Document Type: Article

References (45)

1. Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE (1997) Geometric control of cell life and death. Science 276(5317):1425-1428.
2. Rauzi M, Lecuit T (2009) Closing in on mechanisms of tissue morphogenesis. Cell 137(7):1183-1185.
3. Engler AJ, Sen S, Sweeney HL, Discher DE (2006) Matrix elasticity directs stem cell lineage specification. Cell 126(4):677-689.
4. Ingber DE (2006) Cellular mechanotransduction: Putting all the pieces together again. FASEB J 20(7):811-827.
5. Nelson CM, et al. (2005) Emergent patterns of growth controlled by multicellular form and mechanics. Proc Natl Acad Sci USA 102(33):11594-11599.
6. Provenzano PP, Inman DR, Eliceiri KW, Trier SM, Keely PJ (2008) Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization. Biophys J 95(11):5374-5384.
7. Provenzano PP, Inman DR, Eliceiri KW, Keely PJ (2009) Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage. Oncogene 28(49):4326-4343.
8. Guo CL, et al. (2012) Long-range mechanical force enables self-assembly of epithelial tubular patterns. Proc Natl Acad Sci USA 109(15):5576-5582.
9. Discher DE, Janmey P, Wang YL (2005) Tissue cells feel and respond to the stiffness of their substrate. Science 310(5751):1139-1143.
10. Vader D, Kabla A, Weitz D, Mahadevan L (2009) Strain-induced alignment in collagen gels. PLoS ONE 4(6):e5902.
11. Paszek MJ, et al. (2005) Tensional homeostasis and the malignant phenotype. Cancer Cell 8(3):241-254.
12. Levayer R, Lecuit T (2012) Biomechanical regulation of contractility: Spatial control and dynamics. Trends Cell Biol 22(2):61-81.
13. Sun Y, Chen CS, Fu J (2012) Forcing stem cells to behave: A biophysical perspective of the cellular microenvironment. Annu Rev Biophys 41:519-542.
14. Fernandez P, Bausch AR (2009) The compaction of gels by cells: A case of collective mechanical activity. Integr Biol (Camb) 1(3):252-259.
15. Arnaout MA, Goodman SL, Xiong JP (2007) Structure and mechanics of integrin-based cell adhesion. Curr Opin Cell Biol 19(5):495-507.
16. Schwartz MA, Ginsberg MH (2002) Networks and crosstalk: Integrin signalling spreads. Nat Cell Biol 4(4):E65-E68.
17. Margadant C, Sonnenberg A (2010) Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing. EMBO Rep 11(2):97-105.
18. Shergill B, Meloty-Kapella L, Musse AA, Weinmaster G, Botvinick E (2012) Optical tweezers studies on Notch: Single-molecule interaction strength is independent of ligand endocytosis. Dev Cell 22(6):1313-1320.
19. Wang XF, Ha T (2013) Defining single molecular forces required to activate integrin and notch signaling. Science 340(6135):991-994.
20. Sawhney RK, Howard J (2002) Slow local movements of collagen fibers by fibroblasts drive the rapid global self-organization of collagen gels. J Cell Biol 157(6):1083-1091.
21. Dhimolea E, Maffini MV, Soto AM, Sonnenschein C (2010) The role of collagen reorganization on mammary epithelial morphogenesis in a 3D culture model. Biomaterials 31(13):3622-3630.
22. Conklin MW, et al. (2011) Aligned collagen is a prognostic signature for survival in human breast carcinoma. Am J Pathol 178(3):1221-1232.
23. Levental KR, et al. (2009) Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 139(5):891-906.
24. Bondareva A, et al. (2009) The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells. PLoS ONE 4(5):e5620.
25. Wellings SR, Jensen HM, Marcum RG (1975) An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J Natl Cancer Inst 55(2):231-273.
26. Parsons BL, Meng F (2009) K-RAS mutation in the screening, prognosis and treatment of cancer. Biomarkers Med 3(6):757-769.
27. Wang F, et al. (1998) Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology. Proc Natl Acad Sci USA 95(25):14821-14826.
28. Debnath J, Muthuswamy SK, Brugge JS (2003) Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30(3):256-268.
29. Borghi N, Lowndes M, Maruthamuthu V, Gardel ML, Nelson WJ (2010) Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions. Proc Natl Acad Sci USA 107(30):13324-13329.
30. de Rooij J, Kerstens A, Danuser G, Schwartz MA, Waterman-Storer CM (2005) Integrindependent actomyosin contraction regulates epithelial cell scattering. J Cell Biol 171(1):153-164.
31. Uehata M, et al. (1997) Calcium sensitization of smooth muscle mediated by a Rhoassociated protein kinase in hypertension. Nature 389(6654):990-994.
32. Limouze J, Straight AF, Mitchison T, Sellers JR (2004) Specificity of blebbistatin, an inhibitor of myosin II. J Muscle Res Cell Motil 25(4-5):337-341.
33. Straight AF, et al. (2003) Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science 299(5613):1743-1747.
34. Kiehart DP, Galbraith CG, Edwards KA, Rickoll WL, Montague RA (2000) Multiple forces contribute to cell sheet morphogenesis for dorsal closure in Drosophila. J Cell Biol 149(2):471-490.
35. Kiehart DP, et al. (2006) Ultraviolet Laser Microbeam for Dissection of Drosophila Embryos Cell Biology: A Laboratory Handbook (Elsevier Science, Amsterdam), pp 87-103.
36. Treloar LRG (1973) The elasticity and related properties of rubbers. Rep Prog Phys 36(7):755.
37. Heppner GH, Miller FR, Shekhar PM (2000) Nontransgenic models of breast cancer. Breast Cancer Res 2(5):331-334.
38. Chandler EM, et al. (2012) Implanted adipose progenitor cells as physicochemical regulators of breast cancer. Proc Natl Acad Sci USA 109(25):9786-9791.
39. Neve RM, et al. (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10(6):515-527.
40. Fang X, et al. (2011) Twist2 contributes to breast cancer progression by promoting an epithelial-mesenchymal transition and cancer stem-like cell self-renewal. Oncogene 30(47):4707-4720.
41. Zheng H, Kang Y (2013) Multilayer control of the EMT master regulators. Oncogene, 10.1038/onc.2013.128.
42. Kokkinos MI, et al. (2007) Vimentin and epithelial-mesenchymal transition in human breast cancer?Observations in vitro and in vivo. Cells Tissues Organs 185(1-3): 191-203.
43. Gilles C, Thompson EW (1996) The epithelial to mesenchymal transition and metastatic progression in carcinoma. Breast J 2(1):83-96.
44. Dupont S, et al. (2011) Role of YAP/TAZ in mechanotransduction. Nature 474(7350): 179-183.
45. Lee GY, Kenny PA, Lee EH, Bissell MJ (2007) Three-dimensional culture models of normal and malignant breast epithelial cells. Nat Methods 4(4):359-365.