Aliphatic polyamines in physiology and diseases

Clinical Nutrition

Volumn 33, Issue 1, 2014, Pages 14-22

  Ramani, D ^a   De Bandt, J P ^a   Cynober, L ^a  

^a FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

Author keywords

Agmatine; Cancer; Putrescine; Spermidine; Spermine

Indexed keywords

ACYLTRANSFERASE; ADENOSYLMETHIONINE DECARBOXYLASE; AGMATINE; ORNITHINE DECARBOXYLASE; POLYAMINE; PUTRESCINE; SPERMIDINE; SPERMIDINE SPERMINE ACETYLTRANSFERASE; SPERMINE; UNCLASSIFIED DRUG;

APOPTOSIS; BIOLOGICAL ACTIVITY; CARCINOGENESIS; CELL CYCLE PROGRESSION; CELL JUNCTION; CONGENITAL MALFORMATION; DNA CONFORMATION; GASTROINTESTINAL TRACT FUNCTION; GENE EXPRESSION REGULATION; GENETIC STABILITY; HUMAN; IMMUNE RESPONSE; INTRACELLULAR SIGNALING; MALIGNANT NEOPLASTIC DISEASE; METABOLIC REGULATION; MICROTUBULE; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; NONHUMAN; POLYAMINE METABOLISM; REVIEW; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; TRANSPORT KINETICS;

AGMATINE; CANCER; DFMO; DIFLUOROMETHYLORNITHINE; ODC; ORNITHINE DECARBOXYLASE; PUTRESCINE; S-ADENOSYL-S-METHYL HOMOCYSTEAMINE; S-ADENOSYLMETHIONINE; SAM; SAM DECARBOXYLASE; SAMDC; SAMHC; SPERMIDINE; SPERMIDINE/SPERMINE ACETYLTRANSFERASE; SPERMINE; SSAT;

AGMATINE; ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; NEOPLASMS; ORNITHINE; PUTRESCINE; SPERMIDINE; SPERMINE;

EID: 84892535903     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2013.09.019     Document Type: Review

References (50)

1. Moinard C., Cynober L., de Bandt J.P. Polyamines: metabolism and implications in human diseases. Clin Nutr 2005, 24:184-197.
2. Pegg A.E. Mammalian polyamine metabolism and function. IUBMB Life 2009, 61:880-894.
3. Wallace H.M., Fraser A.V., Hughes A. Aperspective of polyamine metabolism. Biochem J 2003, 376:1-14.
4. Pegg A.E. Regulation of ornithine decarboxylase. JBiol Chem 2006, 281:14529-14532.
5. Bale S., Ealick S.E. Structural biology of S-adenosylmethionine decarboxylase. Amino Acids 2010, 38:451-460.
6. Pegg A.E. Spermidine/spermine-N(1)-acetyltransferase: a key metabolic regulator. Am J Physiol Endocrinol Metab 2008, 294:E995-E1010.
7. Poulin R., Casero R.A., Soulet D. Recent advances in the molecular biology of metazoan polyamine transport. Amino Acids 2012, 42:711-723.
8. Uemura T., Stringer D.E., Blohm-Mangone K.A., Gerner E.W. Polyamine transport is mediated by both endocytic and solute carrier transport mechanisms in the gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol 2010, 299:G517-G522.
9. Igarashi K., Kashiwagi K. Modulation of cellular function by polyamines. Int J Biochem Cell Biol 2010, 42:39-51.
10. Childs A.C., Mehta D.J., Gerner E.W. Polyamine-dependent gene expression. Cell Mol Life Sci 2003, 60:1394-1406.
11. Wei G., Hobbs C.A., Defeo K., Hayes C.S., Gilmour S.K. Polyamine-mediated regulation of protein acetylation in murine skin and tumors. Mol Carcinog 2007, 46:611-617.
12. Rajeeve V., Pearce W., Cascante M., Vanhaesebroeck B., Cutillas P.R. Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth. Biochem J 2013, 450:619-628.
13. Bachrach U., Wang Y.C., Tabib A. Polyamines: new cues in cellular signal transduction. News Physiol Sci 2001, 16:106-109.
14. Wang Y., Devereux W., Stewart T.M., Casero R.A. Cloning and characterization of human polyamine-modulated factor-1, a transcriptional cofactor that regulates the transcription of the spermidine/spermine N(1)-acetyltransferase gene. JBiol Chem 1999, 274:22095-22101.
15. Shah N., Thomas T.J., Lewis J.S., Klinge C.M., Shirahata A., Gelinas C., et al. Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells. Oncogene 2001, 20:1715-1729.
16. Igarashi K., Kashiwagi K. Polyamines: mysterious modulators of cellular functions. Biochem Biophys Res Commun 2000, 271:559-564.
17. Ouameur A.A., Bourassa P., Tajmir-Riahi H.A. Probing tRNA interaction with biogenic polyamines. RNA 2010, 16:1968-1979.
18. Zou T., Rao J.N., Liu L., Xiao L., Yu T.X., Jiang P., et al. Polyamines regulate the stability of JunD mRNA by modulating the competitive binding of its 3' untranslated region to HuR and AUF1. Mol Cell Biol 2010, 30:5021-5032.
19. Park M.H., Nishimura K., Zanelli C.F., Valentini S.R. Functional significance of eIF5A and its hypusine modification in eukaryotes. Amino Acids 2010, 38:491-500.
20. Savarin P., Barbet A., Delga S., Joshi V., Hamon L., Lefevre J., et al. Acentral role for polyamines in microtubule assembly in cells. Biochem J 2010, 430:151-159.
21. Coburn R.F. Polyamine effects on cell function: possible central role of plasma membrane PI(4,5)P2. JCell Physiol 2009, 221:544-551.
22. Schuber F. Influence of polyamines on membrane functions. Biochem J 1989, 260:1-10.
23. Wang J.Y. Polyamines regulate expression of E-cadherin and play an important role in control of intestinal epithelial barrier function. Inflammopharmacology 2005, 13:91-101.
24. Guo X., Rao J.N., Liu L., Zou T., Keledjian K.M., Boneva D., et al. Polyamines are necessary for synthesis and stability of occludin protein in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2005, 288:G1159-G1169.
25. Guo X., Rao J.N., Liu L., Rizvi M., Turner D.J., Wang J.Y. Polyamines regulate beta-catenin tyrosine phosphorylation via Ca(2+) during intestinal epithelial cell migration. Am J Physiol Cell Physiol 2002, 283:C722-C734.
26. Hibino H., Inanobe A., Furutani K., Murakami S., Findlay I., Kurachi Y. Inwardly rectifying potassium channels: their structure, function, and physiological roles. Physiol Rev 2010, 90:291-366.
27. Strømgaard K., Mellor I. AMPA receptor ligands: synthetic and pharmacological studies of polyamines and polyamine toxins. Med Res Rev 2004, 24:589-620.
28. Thomas T., Thomas T.J. Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell Mol Life Sci 2001, 58:244-258.
29. Flamigni F., Stanic' I., Facchini A., Cetrullo S., Tantini B., Borzì R.M., et al. Polyamine biosynthesis as a target to inhibit apoptosis of non-tumoral cells. Amino Acids 2007, 33:197-202.
30. Seiler N., Raul F. Polyamines and the intestinal tract. Crit Rev Clin Lab Sci 2007, 44:365-411.
31. Wang J.Y. Polyamines and mRNA stability in regulation of intestinal mucosal growth. Amino Acids 2007, 33:241-252.
32. Biol-N'Garagba M.C., Greco S., George P., Hugueny I., Louisot P. Polyamine participation in the maturation of glycoprotein fucosylation, but not sialylation, in rat small intestine. Pediatr Res 2002, 51:625-634.
33. Pérez-Cano F.J., González-Castro A., Castellote C., Franch A., Castell M. Influence of breast milk polyamines on suckling rat immune system maturation. Dev Comp Immunol 2010, 34:210-218.
34. Johnson L.R., McCormack S.A. Healing of gastrointestinal mucosa: involvement of polyamines. News Physiol Sci 1999, 14:12-17.
35. Satriano J. Arginine pathways and the inflammatory response: interregulation of nitric oxide and polyamines: review article. Amino Acids 2004, 26:321-329.
36. Popovic P.J., Zeh H.J., Ochoa J.B. Arginine and immunity. JNutr 2007, 137:1681S-1686S.
37. Slotkin T.A., Bartolome J. Role of ornithine decarboxylase and the polyamines in nervous system development: a review. Brain Res Bull 1986, 17:307-320.
38. Schreiber R.C., Boeshore K.L., Laube G., Veh R.W., Zigmond R.E. Polyamines increase in sympathetic neurons and non-neuronal cells after axotomy and enhance neurite outgrowth in nerve growth factor-primed PC12 cells. Neuroscience 2004, 128:741-749.
39. Lefèvre P.L., Palin M.F., Murphy B.D. Polyamines on the reproductive landscape. Endocr Rev 2011, 32:694-712.
40. Gerner E.W., Meyskens F.L. Polyamines and cancer: old molecules, new understanding. Nat Rev Cancer 2004, 4:781-792.
41. Babbar N., Gerner E.W. Targeting polyamines and inflammation for cancer prevention. Recent Results Cancer Res 2011, 188:49-64.
42. Messing E., Kim K.M., Sharkey F., Schultz M., Parnes H., Saltzstein D., et al. Randomized prospective phase III trial of difluoromethylornithine vs placebo in preventing recurrence of completely resected low risk superficial bladder cancer. JUrol 2006, 176:500-504.
43. Wallace H.M., Fraser A.V. Inhibitors of polyamine metabolism: review article. Amino Acids 2004, 26:353-365.
44. Cipolla B.G., Havouis R., Moulinoux J.P. Polyamine reduced diet (PRD) nutrition therapy in hormone refractory prostate cancer patients. Biomed Pharmacother 2010, 64:363-368.
45. Li G., Regunathan S., Barrow C.J., Eshraghi J., Cooper R., Reis D.J. Agmatine: an endogenous clonidine-displacing substance in the brain. Science 1994, 263:966-969.
46. Grillo M.A., Colombatto S. Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine. Amino Acids 2004, 26:3-8.
47. Halaris A., Plietz J. Agmatine: metabolic pathway and spectrum of activity in brain. CNS Drugs 2007, 21:885-900.
48. Uzbay T.I. The pharmacological importance of agmatine in the brain. Neurosci Biobehav Rev 2012, 36:502-519.
49. Wolf C., Brüss M., Hänisch B., Göthert M., von Kügelgen I., Molderings G.J. Molecular basis for the antiproliferative effect of agmatine in tumor cells of colonic, hepatic, and neuronal origin. Mol Pharmacol 2007, 71:276-283.
50. Haenisch B., von Kügelgen I., Bönisch H., Göthert M., Sauerbruch T., Schepke M., et al. Regulatory mechanisms underlying agmatine homeostasis in humans. Am J Physiol Gastrointest Liver Physiol 2008, 295:G1104-G1110.