Healing of gastrointestinal mucosa: Involvement of polyamines

News in Physiological Sciences

Volumn 14, Issue 1, 1999, Pages 12-17

  Johnson, Leonard R ^a   McCormack, Shirley A ^a  

^a UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033470180     PISSN: 08861714     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiologyonline.1999.14.1.12     Document Type: Article

References (15)

1. Banan, A., J.-Y. Wang, S. A. McCormack, and L. R. Johnson. Relationship between polyamines, actin distribution, and gastric healing in rats. Am. J. Physiol. 271 (Gastrointest. Liver Physiol. 34): G893-G903, 1996.
2. Ciacci, C., S. E. Lind, and D. K. Podolsky. Transforming growth factor β regulation of migration in wounded rat intestinal epithelial monolayers. Gastroenterology 105: 93-101, 1993.
3. Göke, M., M. Kanai, K. Lynch-Devaney, and D. K. Podolsky. Rapid mitogen-activated protein kinase activation by transforming growth factor a in wounded rat intestinal epithelial cells. Gastroenterology 114: 697-705, 1998.
4. McCormack, S. A., P. M. Blanner, B. J. Zimmerman, R. Ray, H. M. Poppleton, T. B. Patel, and L. R. Johnson. Polyamine deficiency alters ECF receptor distribution and signaling effectiveness in IEC-6 cells. Am. J. Physiol. 274 (Cell Physiol. 43): C192-C205, 1998.
5. McCormack, S. A., and L. R. Johnson. Putrescine uptake and release by a normal rat small intestine crypt cell line, IEC-6. Exp. Cell Res. 193: 241-252, 1991.
6. McCormack, S. A., M. J. Viar, and L. R. Johnson. Migration of IEC-6 cells: a model for mucosal healing. Am. J. Physiol. 263 (Gastrointest. Liver Physiol. 26) G426-G435, 1992.
7. McCormack, S. A., J.-Y. Wang, and L. R. Johnson. Polyamine deficiency causes reorganization of F-actin and tropomyosin in IEC-6 cells. Am. J. Physiol. 267 (Cell Physiol. 36): C715-C722, 1994.
8. Pegg, A. E. and P. P. McCann. Polyamine metabolism and function. Am. J. Physiol. 243 (Cell Physiol. 12): C212-C221, 1982.
9. Santos, M. F., S. A. McCormack, Z. Guo, J. Okolicany, Y. Zheng, L. R. Johnson, and G. Tigyi. Rho proteins play a critical role in cell migration during the early phase of mucosal restitution. J. Clin. Invest. 100: 216-225, 1997.
10. Schuber, F. Influence of polyamines on membrane functions. Biochem J. 260: 1-10, 1989.
11. Silen, W. Gastric mucosal defense and repair. In: Physiology of the Gastrointestinal Tract (2nd ed.), edited by L. R. Johnson. New York: Raven, 1987, p. 1055-1069.
12. Wang, J.-Y., and L. R. Johnson. Luminal polyamines stimulate repair of gastric mucosal stress ulcers. Am. J. Physiol. 259 (Gastrointest. Liver Physiol. 22): G584-G592, 1990.
13. Wang, J.-Y., and L. R. Johnson. Luminal polyamines substitute for tissue polyamines in duodenal mucosal repair after stress in rats. Gastroenterology 102: 1109-1117, 1992.
14. Wang, J.-Y., and L. R. Johnson. Expression of protooncogenes c-fos and c-myc in healing of gastric mucosal stress ulcers. Am. J. Physiol. 266 (Gastrointest. Liver Physiol. 29): G878-G886, 1994.
15. Wang, J.-Y., M. J. Viar, J. Li, H. J. Shi, S. A. McCormack, and L. R. Johnson. Polyamines are necessary for normal expression of the transforming growth factor-β gene during cell migration. Am. J. Physiol. 272 (Gastrointest. Liver Physiol. 35): G713-G720, 1997.