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Volumn 30, Issue 21, 2010, Pages 5021-5032

Polyamines regulate the stability of JunD mRNA by modulating the competitive binding of its 3′ untranslated region to HuR and AUF1

Author keywords

[No Author keywords available]

Indexed keywords

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; HUR PROTEIN; MESSENGER RNA; POLYAMINE; TRANSCRIPTION FACTOR JUND; 3' UNTRANSLATED REGION; ELAVL1 PROTEIN, HUMAN; HNRNP D0; HU ANTIGEN; MEMBRANE ANTIGEN; PRIMER DNA; RNA BINDING PROTEIN; SMALL INTERFERING RNA;

EID: 77957841913     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00807-10     Document Type: Article
Times cited : (60)

References (64)
  • 2
    • 40149096226 scopus 로고    scopus 로고
    • Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: Implications for cellular senescence
    • Abdelmohsen, K., Y. Kuwano, H. H. Kim, and M. Gorospe. 2008. Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol. Chem. 389:243-255.
    • (2008) Biol. Chem. , vol.389 , pp. 243-255
    • Abdelmohsen, K.1    Kuwano, Y.2    Kim, H.H.3    Gorospe, M.4
  • 3
    • 67649354548 scopus 로고    scopus 로고
    • JunD and HIF-1α mediate transcriptional activation of angiotensinogen by TGF-β1 in human lung fibroblasts
    • Abdul-Hafez, A., R. Shu, and B. D. Uhal. 2009. JunD and HIF-1α mediate transcriptional activation of angiotensinogen by TGF-β1 in human lung fibroblasts. FASEB J. 23:1655-1662.
    • (2009) FASEB J. , vol.23 , pp. 1655-1662
    • Abdul-Hafez, A.1    Shu, R.2    Uhal, B.D.3
  • 4
    • 4544348925 scopus 로고    scopus 로고
    • Stability of A+U-rich element binding factor 1 (AUF1)-binding messenger ribonucleic acid correlates with the subcellular relocalization of AUF1 in the rat uterus upon estrogen treatment
    • Arao, Y., A. Kikuchi, M. Kishida, M. Yonekura, A. Inoue, S. Yasuda, S. Wada, K. Ikeda, and F. Kayama. 2004. Stability of A+U-rich element binding factor 1 (AUF1)-binding messenger ribonucleic acid correlates with the subcellular relocalization of AUF1 in the rat uterus upon estrogen treatment. Mol. Endocrinol. 18:2255-2267.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 2255-2267
    • Arao, Y.1    Kikuchi, A.2    Kishida, M.3    Yonekura, M.4    Inoue, A.5    Yasuda, S.6    Wada, S.7    Ikeda, K.8    Kayama, F.9
  • 5
    • 0035162672 scopus 로고    scopus 로고
    • ARED: Human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins
    • Bakheet, T., M. Frevel, B. R. Williams, W. Greer, and K. S. Khabar. 2001. ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins. Nucleic Acids Res. 29:246-254.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 246-254
    • Bakheet, T.1    Frevel, M.2    Williams, B.R.3    Greer, W.4    Khabar, K.S.5
  • 8
    • 34248228763 scopus 로고    scopus 로고
    • Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases
    • Casero, R. A., Jr., and L. J. Marton. 2007. Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases. Nat. Rev. Drug Discov. 6:373-390.
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 373-390
    • Casero Jr., R.A.1    Marton, L.J.2
  • 9
    • 55549114048 scopus 로고    scopus 로고
    • JunD represses transcription and translation of the tight junction protein zona occludens-1 modulating intestinal epithelial barrier function
    • Chen, J., L. Xiao, J. N. Rao, T. Zou, L. Liu, E. Bellavance, M. Gorospe, and J. Y. Wang. 2008. JunD represses transcription and translation of the tight junction protein zona occludens-1 modulating intestinal epithelial barrier function. Mol. Biol. Cell 19:3701-3712.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 3701-3712
    • Chen, J.1    Xiao, L.2    Rao, J.N.3    Zou, T.4    Liu, L.5    Bellavance, E.6    Gorospe, M.7    Wang, J.Y.8
  • 11
    • 4944242891 scopus 로고    scopus 로고
    • Polyamines and cancer: Old molecules, new understanding
    • Gerner, E. W., and F. L. Meyskens, Jr. 2004. Polyamines and cancer: old molecules, new understanding. Nat. Rev. Cancer 4:781-792.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 781-792
    • Gerner, E.W.1    Meyskens Jr., F.L.2
  • 12
    • 2942612333 scopus 로고    scopus 로고
    • A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery
    • Gherzi, R., K. Y. Lee, P. Briata, D. Wegmüller, C. Moroni, M. Karin, and C. Y. Chen. 2004. A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Mol. Cell 14:571-583.
    • (2004) Mol. Cell , vol.14 , pp. 571-583
    • Gherzi, R.1    Lee, K.Y.2    Briata, P.3    Wegmüller, D.4    Moroni, C.5    Karin, M.6    Chen, C.Y.7
  • 13
    • 0000371335 scopus 로고
    • Critical values for Duncan's new multiple range test
    • Harter, J. L. 1960. Critical values for Duncan's new multiple range test. Biometrics 16:671-685.
    • (1960) Biometrics , vol.16 , pp. 671-685
    • Harter, J.L.1
  • 14
    • 49649113832 scopus 로고    scopus 로고
    • Multiple facets of junD gene expression are atypical among AP-1 family members
    • Hernandez, J. M., D. H. Floyd, K. N. Weilbaecher, P. L. Green, and K. Boris-Lawrie. 2008. Multiple facets of junD gene expression are atypical among AP-1 family members. Oncogene 27:4757-4767.
    • (2008) Oncogene , vol.27 , pp. 4757-4767
    • Hernandez, J.M.1    Floyd, D.H.2    Weilbaecher, K.N.3    Green, P.L.4    Boris-Lawrie, K.5
  • 16
    • 53849124668 scopus 로고    scopus 로고
    • Diverse molecular functions of Hu proteins
    • Hinman, M. N., and H. Lou. 2008. Diverse molecular functions of Hu proteins. Cell Mol. Life Sci. 65:3168-3181.
    • (2008) Cell Mol. Life Sci. , vol.65 , pp. 3168-3181
    • Hinman, M.N.1    Lou, H.2
  • 18
    • 60149090021 scopus 로고    scopus 로고
    • The many pathways of RNA degradation
    • Houseley, J., and D. Tollervey. 2009. The many pathways of RNA degradation. Cell 136:763-776.
    • (2009) Cell , vol.136 , pp. 763-776
    • Houseley, J.1    Tollervey, D.2
  • 19
  • 21
    • 34250735674 scopus 로고    scopus 로고
    • RNA regulons: Coordination of post-transcriptional events
    • Keene, J. D. 2007. RNA regulons: coordination of post-transcriptional events. Nat. Rev. Genet. 8:533-543.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 533-543
    • Keene, J.D.1
  • 23
    • 4143122397 scopus 로고    scopus 로고
    • Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
    • DOI 10.1038/sj.emboj.7600305
    • Lal, A., K. Mazan-Mamczarz, T. Kawai, X. Yang, J. L. Martindale, and M. Gorospe. 2004. Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J. 23:3092-3102. (Pubitemid 39093603)
    • (2004) EMBO Journal , vol.23 , Issue.15 , pp. 3092-3102
    • Lal, A.1    Mazan-Mamczarz, K.2    Kawai, T.3    Yang, X.4    Martindale, J.L.5    Gorospe, M.6
  • 25
    • 0033574789 scopus 로고    scopus 로고
    • Control of mRNA decay by heat shock-ubiquitin-proteasome pathway
    • Laroia, G., R. Cuesta, G. Brewer, and R. J. Schneider. 1999. Control of mRNA decay by heat shock-ubiquitin-proteasome pathway. Science 284:499-502.
    • (1999) Science , vol.284 , pp. 499-502
    • Laroia, G.1    Cuesta, R.2    Brewer, G.3    Schneider, R.J.4
  • 27
    • 0032924823 scopus 로고    scopus 로고
    • Inhibition of polyamine synthesis induces p53 gene expression but not apoptosis
    • Li, L., J. Li, J. N. Rao, M. Li, B. L. Bass, and J. Y. Wang. 1999. Inhibition of polyamine synthesis induces p53 gene expression but not apoptosis. Am. J. Physiol. Cell Physiol. 276:C946-C954.
    • (1999) Am. J. Physiol. Cell Physiol. , vol.276
    • Li, L.1    Li, J.2    Rao, J.N.3    Li, M.4    Bass, B.L.5    Wang, J.Y.6
  • 28
    • 0034830491 scopus 로고    scopus 로고
    • Polyamine depletion stabilizes p53 resulting in inhibition of normal intestinal epithelial cell proliferation
    • Li, L., J. N. Rao, X. Guo, L. Liu, R. Santora, B. L. Bass, and J. Y. Wang. 2001. Polyamine depletion stabilizes p53 resulting in inhibition of normal intestinal epithelial cell proliferation. Am. J. Physiol. Cell Physiol. 281:C941-C953.
    • (2001) Am. J. Physiol. Cell Physiol. , vol.281
    • Li, L.1    Rao, J.N.2    Guo, X.3    Liu, L.4    Santora, R.5    Bass, B.L.6    Wang, J.Y.7
  • 29
    • 0036727932 scopus 로고    scopus 로고
    • JunD stabilization results in inhibition of normal intestinal epithelial cell growth through P21 after polyamine depletion
    • Li, L., L. Liu, J. N. Rao, A. Esmaili, E. D. Strauch, B. L. Bass, and J. Y. Wang. 2002. JunD stabilization results in inhibition of normal intestinal epithelial cell growth through P21 after polyamine depletion. Gastroenterology 123:764-779.
    • (2002) Gastroenterology , vol.123 , pp. 764-779
    • Li, L.1    Liu, L.2    Rao, J.N.3    Esmaili, A.4    Strauch, E.D.5    Bass, B.L.6    Wang, J.Y.7
  • 30
    • 34249875986 scopus 로고    scopus 로고
    • Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation
    • Liao, B., Y. Hu, and G. Brewer. 2007. Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation. Nat. Struct. Mol. Biol. 14:511-518.
    • (2007) Nat. Struct. Mol. Biol. , vol.14 , pp. 511-518
    • Liao, B.1    Hu, Y.2    Brewer, G.3
  • 31
    • 33748343207 scopus 로고    scopus 로고
    • Polyamine-modulated c-Myc expression in normal intestinal epithelial cells regulates p21Cip1 transcription through a proximal promoter region
    • Liu, L., X. Guo, J. N. Rao, T. Zou, B. S. Marasa, J. Chen, J. Greenspon, R. A. Casero, Jr., and J. Y. Wang. 2006. Polyamine-modulated c-Myc expression in normal intestinal epithelial cells regulates p21Cip1 transcription through a proximal promoter region. Biochem. J. 398:257-267.
    • (2006) Biochem. J. , vol.398 , pp. 257-267
    • Liu, L.1    Guo, X.2    Rao, J.N.3    Zou, T.4    Marasa, B.S.5    Chen, J.6    Greenspon, J.7    Casero Jr., R.A.8    Wang, J.Y.9
  • 37
    • 44849134637 scopus 로고    scopus 로고
    • JunD mediates antidrogen-induced oxidative stress in androgen dependent LNCaP human prostate cancer cells
    • Mehraein-Ghomi, F., E. Lee, D. R. Church, T. A. Thompson, H. S. Basu, and G. Wilding. 2008. JunD mediates antidrogen-induced oxidative stress in androgen dependent LNCaP human prostate cancer cells. Prostate 68:924-934.
    • (2008) Prostate , vol.68 , pp. 924-934
    • Mehraein-Ghomi, F.1    Lee, E.2    Church, D.R.3    Thompson, T.A.4    Basu, H.S.5    Wilding, G.6
  • 38
    • 77955712545 scopus 로고    scopus 로고
    • Jun and JunD-dependent functions in cell proliferation and stress response
    • Meixner, A., F. Karreth, L. Kenner, J. M. Penninger, and E. F. Wagner. 2010. Jun and JunD-dependent functions in cell proliferation and stress response. Cell Death Differ. 17:1409-1419.
    • (2010) Cell Death Differ. , vol.17 , pp. 1409-1419
    • Meixner, A.1    Karreth, F.2    Kenner, L.3    Penninger, J.M.4    Wagner, E.F.5
  • 39
    • 24644502657 scopus 로고    scopus 로고
    • From birth to death: The complex lives of eukaryotic mRNAs
    • Moore, M. J. 2005. From birth to death: the complex lives of eukaryotic mRNAs. Science 309:1514-1518.
    • (2005) Science , vol.309 , pp. 1514-1518
    • Moore, M.J.1
  • 40
    • 0031818503 scopus 로고    scopus 로고
    • Expression of the transforming growth factor-β gene during growth inhibition following polyamine depletion
    • Patel, A. R., J. Li, B. L. Bass, and J. Y. Wang. 1998. Expression of the transforming growth factor-β gene during growth inhibition following polyamine depletion. Am. J. Physiol. Cell Physiol. 275:C590-C598.
    • (1998) Am. J. Physiol. Cell Physiol. , vol.275
    • Patel, A.R.1    Li, J.2    Bass, B.L.3    Wang, J.Y.4
  • 41
    • 0032956891 scopus 로고    scopus 로고
    • Polyamine depletion is associated with and increase in JunD/AP-1 activity in small intestinal crypt cells
    • Patel, A. R., and J. Y. Wang. 1999. Polyamine depletion is associated with and increase in JunD/AP-1 activity in small intestinal crypt cells. Am. J. Physiol. Gastrointest. Liver Physiol. 276:G441-G450.
    • (1999) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.276
    • Patel, A.R.1    Wang, J.Y.2
  • 43
    • 0018394382 scopus 로고
    • Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria
    • Quaroni, A., J. Wands, R. L. Trelstad, and K. J. Isselbacher. 1979. Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria. J. Cell Biol. 80:248-265.
    • (1979) J. Cell Biol. , vol.80 , pp. 248-265
    • Quaroni, A.1    Wands, J.2    Trelstad, R.L.3    Isselbacher, K.J.4
  • 44
    • 2542596992 scopus 로고    scopus 로고
    • Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference
    • Raineri, I., D. Wegmueller, B. Gross, U. Certa, and C. Moroni. 2004. Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference. Nucleic Acids Res. 32:1279-1288.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1279-1288
    • Raineri, I.1    Wegmueller, D.2    Gross, B.3    Certa, U.4    Moroni, C.5
  • 45
    • 0032895918 scopus 로고    scopus 로고
    • Polyamine depletion arrests cell cycle and induces inhibitors p21(Waf1/Cip1), p27(Kip1), and p53 in IEC-6 cells
    • Ray, R. M., B. J. Zimmerman, S. A. McCormack, T. B. Patel, and L. R. Johnson. 1999. Polyamine depletion arrests cell cycle and induces inhibitors p21(Waf1/Cip1), p27(Kip1), and p53 in IEC-6 cells. Am. J. Physiol. Cell Physiol. 276:C684-C691.
    • (1999) Am. J. Physiol. Cell Physiol. , vol.276
    • Ray, R.M.1    Zimmerman, B.J.2    McCormack, S.A.3    Patel, T.B.4    Johnson, L.R.5
  • 46
    • 0034629124 scopus 로고    scopus 로고
    • Identification of AUF1 as a parathyroid hormone mRNA 3′- untranslated regionbinding protein that determines parathyroid hormone mRNA stability
    • Sela-Brown, A., J. Silver, G. Brewer, and T. Naveh-Many. 2000. Identification of AUF1 as a parathyroid hormone mRNA 3′-untranslated regionbinding protein that determines parathyroid hormone mRNA stability. J. Biol. Chem. 275:7424-7429.
    • (2000) J. Biol. Chem. , vol.275 , pp. 7424-7429
    • Sela-Brown, A.1    Silver, J.2    Brewer, G.3    Naveh-Many, T.4
  • 47
    • 0033984696 scopus 로고    scopus 로고
    • Targeted disruption of the murine junD gene results in multiple defects in male reproductive function
    • Thépot, D., J. B. Weitzman, J. Barra, D. Segretain, M. G. Stinnakre, C. Babinet, and M. Yaniv. 2000. Targeted disruption of the murine junD gene results in multiple defects in male reproductive function. Development 127:143-153. (Pubitemid 30064396)
    • (2000) Development , vol.127 , Issue.1 , pp. 143-153
    • Thepot, D.1    Weitzman, J.B.2    Barra, J.3    Segretain, D.4    Stinnakre, M.-G.5    Babinet, C.6    Yaniv, M.7
  • 48
    • 27844572844 scopus 로고    scopus 로고
    • JunD activates transcription of the human ferritin H gene through an antioxidant response element during oxidative stress
    • Tsuji, Y. 2005. JunD activates transcription of the human ferritin H gene through an antioxidant response element during oxidative stress. Oncogene 24:7567-7578.
    • (2005) Oncogene , vol.24 , pp. 7567-7578
    • Tsuji, Y.1
  • 50
    • 0026025829 scopus 로고
    • Polyamines and ornithine decarboxylase during repair of duodenal mucosa after stress in rats
    • Wang, J. Y., and L. R. Johnson. 1991. Polyamines and ornithine decarboxylase during repair of duodenal mucosa after stress in rats. Gastroenterology 100:333-343.
    • (1991) Gastroenterology , vol.100 , pp. 333-343
    • Wang, J.Y.1    Johnson, L.R.2
  • 51
    • 0028121520 scopus 로고
    • Expression of protooncogenes c-fos and c-myc in healing of gastric mucosal stress ulcers
    • Wang, J. Y., and L. R. Johnson. 1994. Expression of protooncogenes c-fos and c-myc in healing of gastric mucosal stress ulcers. Am. J. Physiol. Gastrointest. Liver Physiol. 266:G878-G886.
    • (1994) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.266
    • Wang, J.Y.1    Johnson, L.R.2
  • 52
    • 34547680515 scopus 로고    scopus 로고
    • Polyamines and mRNA stability in regulation of intestinal mucosal growth
    • Wang, J. Y. 2007. Polyamines and mRNA stability in regulation of intestinal mucosal growth. Amino Acids 33:241-252.
    • (2007) Amino Acids , vol.33 , pp. 241-252
    • Wang, J.Y.1
  • 53
    • 77951473777 scopus 로고    scopus 로고
    • Post-transcriptional regulation of MEK-1 by polyamines through the RNA-binding protein HuR modulating intestinal epithelial apoptosis
    • Wang, P. Y., J. N. Rao, T. Zou, L. Liu, L. Xiao, T. X. Yu, D. J. Turner, M. Gorospe, and J. Y. Wang. 2010. Post-transcriptional regulation of MEK-1 by polyamines through the RNA-binding protein HuR modulating intestinal epithelial apoptosis. Biochem. J. 426:293-306.
    • (2010) Biochem. J. , vol.426 , pp. 293-306
    • Wang, P.Y.1    Rao, J.N.2    Zou, T.3    Liu, L.4    Xiao, L.5    Yu, T.X.6    Turner, D.J.7    Gorospe, M.8    Wang, J.Y.9
  • 54
  • 55
    • 4444324795 scopus 로고    scopus 로고
    • Bringing the role of mRNA decay in the control of gene expression into focus
    • Wilusz, C. J., and J. Wilusz. 2004. Bringing the role of mRNA decay in the control of gene expression into focus. Trends Genet. 20:491-497.
    • (2004) Trends Genet. , vol.20 , pp. 491-497
    • Wilusz, C.J.1    Wilusz, J.2
  • 56
    • 0033521651 scopus 로고    scopus 로고
    • C-Jun regulates cell cycle progression and apoptosis by distinct mechanisms
    • DOI 10.1093/emboj/18.1.188
    • Wisdom, R., R. S. Johnson, and C. Moore. 1999. c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J. 18:188-197. (Pubitemid 29005035)
    • (1999) EMBO Journal , vol.18 , Issue.1 , pp. 188-197
    • Wisdom, R.1    Johnson, R.S.2    Moore, C.3
  • 57
    • 34247860698 scopus 로고    scopus 로고
    • Induced JunD in intestinal epithelial cells represses CDK4 transcription through its proximal promoter region following polyamine depletion
    • Xiao, L., J. N. Rao, T. Zou, L. Liu, B. S. Marasa, J. Chen, D. J. Turner, A. Passaniti, and J. Y. Wang. 2007. Induced JunD in intestinal epithelial cells represses CDK4 transcription through its proximal promoter region following polyamine depletion. Biochem. J. 403:573-581.
    • (2007) Biochem. J. , vol.403 , pp. 573-581
    • Xiao, L.1    Rao, J.N.2    Zou, T.3    Liu, L.4    Marasa, B.S.5    Chen, J.6    Turner, D.J.7    Passaniti, A.8    Wang, J.Y.9
  • 58
    • 35848932765 scopus 로고    scopus 로고
    • Polyamines regulate the stability of activating transcription factor-2 mRNA through RNA-binding protein HuR in intestinal epithelial cells
    • Xiao, L., J. N. Rao, T. Zou, L. Liu, B. S. Marasa, J. Chen, D. J. Turner, H. Zhou, M. Gorospe, and J. Y. Wang. 2007. Polyamines regulate the stability of activating transcription factor-2 mRNA through RNA-binding protein HuR in intestinal epithelial cells. Mol. Biol. Cell 18:4579-4590.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 4579-4590
    • Xiao, L.1    Rao, J.N.2    Zou, T.3    Liu, L.4    Marasa, B.S.5    Chen, J.6    Turner, D.J.7    Zhou, H.8    Gorospe, M.9    Wang, J.Y.10
  • 59
    • 77951431533 scopus 로고    scopus 로고
    • Induced ATF-2 represses CDK4 transcription through dimerization with JunD inhibiting intestinal epithelial cell growth after polyamine depletion
    • Xiao, L., J. N. Rao, T. Zou, L. Liu, T. X. Yu, X. Y. Zhu, J. M. Donahue, and J. Y. Wang. 2010. Induced ATF-2 represses CDK4 transcription through dimerization with JunD inhibiting intestinal epithelial cell growth after polyamine depletion. Am. J. Physiol. Cell Physiol. 298:C1226-C1234.
    • (2010) Am. J. Physiol. Cell Physiol. , vol.298
    • Xiao, L.1    Rao, J.N.2    Zou, T.3    Liu, L.4    Yu, T.X.5    Zhu, X.Y.6    Donahue, J.M.7    Wang, J.Y.8
  • 60
    • 34547138911 scopus 로고    scopus 로고
    • p53-dependent NDRG1 expression induces inhibition of intestinal epithelial cell proliferation but not apoptosis after polyamine depletion
    • Zhang, A. H., J. N. Rao, T. Zou, L. liu, B. S. Marasa, L. Xiao, J. Chen, D. J. Turner, and J. Y. Wang. 2007. p53-dependent NDRG1 expression induces inhibition of intestinal epithelial cell proliferation but not apoptosis after polyamine depletion. Am. J. Physiol. Cell Physiol. 293:C379-C389.
    • (2007) Am. J. Physiol. Cell Physiol. , vol.293
    • Zhang, A.H.1    Rao, J.N.2    Zou, T.3    Liu, L.4    Marasa, B.S.5    Xiao, L.6    Chen, J.7    Turner, D.J.8    Wang, J.Y.9
  • 63
    • 33745849149 scopus 로고    scopus 로고
    • Polyamine depletion increases cytoplasmic levels of RNA-binding protein HuR leading to stabilization of nucleophosmin and p53 mRNAs
    • Zou, T., K. Mazan-Mamczarz, J. N. Rao, L. Liu, B. S. Marasa, A. H. Zhang, L. Xiao, R. Pullmann, M. Gorospe, and J. Y. Wang. 2006. Polyamine depletion increases cytoplasmic levels of RNA-binding protein HuR leading to stabilization of nucleophosmin and p53 mRNAs. J. Biol. Chem. 281:19387-19394.
    • (2006) J. Biol. Chem. , vol.281 , pp. 19387-19394
    • Zou, T.1    Mazan-Mamczarz, K.2    Rao, J.N.3    Liu, L.4    Marasa, B.S.5    Zhang, A.H.6    Xiao, L.7    Pullmann, R.8    Gorospe, M.9    Wang, J.Y.10
  • 64
    • 38749154721 scopus 로고    scopus 로고
    • Polyamines modulate the subcellular localization of RNA-binding protein HuR through AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1
    • Zou, T., L. Liu, J. N. Rao, B. S. Marasa, J. Chen, L. Xiao, H. Zhou, M. Gorospe, and J. Y. Wang. 2008. Polyamines modulate the subcellular localization of RNA-binding protein HuR through AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1. Biochem. J. 409:389-398.
    • (2008) Biochem. J. , vol.409 , pp. 389-398
    • Zou, T.1    Liu, L.2    Rao, J.N.3    Marasa, B.S.4    Chen, J.5    Xiao, L.6    Zhou, H.7    Gorospe, M.8    Wang, J.Y.9


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