Polyamine biosynthesis as a target to inhibit apoptosis of non-tumoral cells

Amino Acids

Volumn 33, Issue 2, 2007, Pages 197-202

  Flamigni, F ^a   Stanic', I ^a   Facchini, A ^a   Cetrullo, S ^a   Tantini, B ^a   Borzi R M ^b   Guarnieri, C ^a   Caldarera, C M ^c  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^c National Institute for Cardiovascular Research   (Italy)

Author keywords

Apoptosis; Caspases; Difluoromethylornithine; Non tumoral cells; Polyamines; Signal transduction

Indexed keywords

4 AMIDINO 1 INDANONE 2' AMIDINOHYDRAZONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 3; CASPASE 8 INHIBITOR; CASPASE 9 INHIBITOR; CYCLOHEXIMIDE; DEATH RECEPTOR; EFLORNITHINE; ORNITHINE DECARBOXYLASE; POLYAMINE; PROTEIN KINASE B INHIBITOR; PUTRESCINE; STAUROSPORINE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID SYNTHESIS; APOPTOSIS; BIOSYNTHESIS; CANCER; CANCER THERAPY; CARTILAGE CELL; CELL SURVIVAL; CYTOTOXICITY; DRUG MECHANISM; DRUG TARGETING; ENZYME INHIBITION; HEART MUSCLE CELL; HUMAN; INHIBITION KINETICS; INTESTINE EPITHELIUM CELL; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; REVIEW; STEM CELL; TUMOR CELL; TUMOR CELL DESTRUCTION;

AMIDINES; ANIMALS; APOPTOSIS; BIOGENIC POLYAMINES; CASPASES; CELL SURVIVAL; CHONDROCYTES; EFLORNITHINE; HUMANS; INDANS; MYOCYTES, CARDIAC; ORNITHINE DECARBOXYLASE; PEPTIDE HYDROLASES; PUTRESCINE; SIGNAL TRANSDUCTION; SPERMIDINE;

EID: 34547663824     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-007-0514-3     Document Type: Review

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