Pyrogallol inhibits the growth of lung cancer Calu-6 cells via caspase-dependent apoptosis

Chemico-Biological Interactions

Volumn 177, Issue 2, 2009, Pages 107-114

  Han, Yong Hwan ^a   Kim, Sung Zoo ^a   Kim, Suhn Hee ^a   Park, Woo Hyun ^a  

^a Department of Physiology   (South Korea)

Author keywords

Apoptosis; Calu 6; Caspase; Pyrogallol; ROS

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PYROGALLOL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PROTEIN SECRETION;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 8; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; G1 PHASE; HUMANS; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; OLIGOPEPTIDES; PYROGALLOL;

EID: 57749202693     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.10.014     Document Type: Article

References (33)

1. Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol. Cell 9 3 (2002) 459-470
2. Ashkenazi A., and Dixit V.M. Death receptors: signaling and modulation. Science 281 5381 (1998) 1305-1308
3. Budihardjo I., Oliver H., Lutter M., Luo X., and Wang X. Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15 (1999) 269-290
4. Mehmet H. Caspases find a new place to hide. Nature 403 6765 (2000) 29-30
5. Hengartner M.O. The biochemistry of apoptosis. Nature 407 6805 (2000) 770-776
6. Liu X., Yue P., Zhou Z., Khuri F.R., and Sun S.Y. Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells. J. Natl. Cancer Inst. 96 23 (2004) 1769-1780
7. Saeki K., Hayakawa S., Isemura M., and Miyase T. Importance of a pyrogallol-type structure in catechin compounds for apoptosis-inducing activity. Phytochemistry 53 3 (2000) 391-394
8. Yamada J., Yoshimura S., Yamakawa H., Sawada M., Nakagawa M., Hara S., Kaku Y., Iwama T., Naganawa T., Banno Y., Nakashima S., and Sakai N. Cell permeable ROS scavengers, Tiron and Tempol, rescue PC12 cell death caused by pyrogallol or hypoxia/reoxygenation. Neurosci. Res. 45 1 (2003) 1-8
9. Gonzalez C., Sanz-Alfayate G., Agapito M.T., Gomez-Nino A., Rocher A., and Obeso A. Significance of ROS in oxygen sensing in cell systems with sensitivity to physiological hypoxia. Respir. Physiol. Neurobiol. 132 1 (2002) 17-41
10. Baran C.P., Zeigler M.M., Tridandapani S., and Marsh C.B. The role of ROS and RNS in regulating life and death of blood monocytes. Curr. Pharm. Des. 10 8 (2004) 855-866
11. Bubici C., Papa S., Pham C.G., Zazzeroni F., and Franzoso G. The NF-kappaB-mediated control of ROS and JNK signaling. Histol. Histopathol. 21 1 (2006) 69-80
12. Zorov D.B., Juhaszova M., and Sollott S.J. Mitochondrial ROS-induced ROS release: an update and review. Biochim. Biophys. Acta 1757 5-6 (2006) 509-517
13. Zelko I.N., Mariani T.J., and Folz R.J. Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic. Biol. Med. 33 3 (2002) 337-349
14. Wilcox C.S. Reactive oxygen species: roles in blood pressure and kidney function. Curr. Hypertens. Rep. 4 2 (2002) 160-166
15. Chen T.J., Jeng J.Y., Lin C.W., Wu C.Y., and Chen Y.C. Quercetin inhibition of ROS-dependent and -independent apoptosis in rat glioma C6 cells. Toxicology 223 1-2 (2006) 113-126
16. Dasmahapatra G., Rahmani M., Dent P., and Grant S. The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism. Blood 107 1 (2006) 232-240
17. Wallach-Dayan S.B., Izbicki G., Cohen P.Y., Gerstl-Golan R., Fine A., and Breuer R. Bleomycin initiates apoptosis of lung epithelial cells by ROS but not by Fas/FasL pathway. Am. J. Physiol. Lung Cell Mol. Physiol. 290 4 (2006) L790-L796
18. Simon H.U., Haj-Yehia A., and Levi-Schaffer F. Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 5 5 (2000) 415-418
19. Moreno-Manzano V., Ishikawa Y., Lucio-Cazana J., and Kitamura M. Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-alpha-induced apoptosis of rat mesangial cells. J. Biol. Chem. 275 17 (2000) 12684-12691
20. Sawada M., Nakashima S., Kiyono T., Nakagawa M., Yamada J., Yamakawa H., Banno Y., Shinoda J., Nishimura Y., Nozawa Y., and Sakai N. p53 regulates ceramide formation by neutral sphingomyelinase through reactive oxygen species in human glioma cells. Oncogene 20 11 (2001) 1368-1378
21. Park W.H., Han Y.W., Kim S.H., and Kim S.Z. A superoxide anion generator, pyrogallol induces apoptosis in As4.1 cells through the depletion of intracellular GSH content. Mutat. Res. 619 1-2 (2007) 81-92
22. Petty R.D., Nicolson M.C., Kerr K.M., Collie-Duguid E., and Murray G.I. Gene expression profiling in non-small cell lung cancer: from molecular mechanisms to clinical application. Clin. Cancer Res. 10 10 (2004) 3237-3248
23. Park W.H., Seol J.G., Kim E.S., Hyun J.M., Jung C.W., Lee C.C., Kim B.K., and Lee Y.Y. Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis. Cancer Res. 60 11 (2000) 3065-3071
24. Han Y.H., Kim S.Z., Kim S.H., and Park W.H. Arsenic trioxide inhibits growth of As4.1 juxtaglomerular cells via cell cycle arrest and caspase-independent apoptosis. Am. J. Physiol. Renal Physiol. 293 2 (2007) F511-520
25. Porter A.G., and Janicke R.U. Emerging roles of caspase-3 in apoptosis. Cell Death Differ. 6 2 (1999) 99-104
26. Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., and Earnshaw W.C. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371 6495 (1994) 346-347
27. Han Y.H., Kim S.Z., Kim S.H., and Park W.H. Apoptosis in pyrogallol-treated Calu-6 cells is correlated with the changes of intracellular GSH levels rather than ROS levels. Lung Cancer 59 3 (2008) 301-314
28. Coutts A.S., and La Thangue N. The p53 response during DNA damage: impact of transcriptional cofactors. Biochem. Soc. Symp. 73 (2006) 181-189
29. Caamano J., Ruggeri B., Momiki S., Sickler A., Zhang S.Y., and Klein-Szanto A.J. Detection of p53 in primary lung tumors and nonsmall cell lung carcinoma cell lines. Am. J. Pathol. 139 4 (1991) 839-845
30. Yang J., Liu X., Bhalla K., Kim C.N., Ibrado A.M., Cai J., Peng T.I., Jones D.P., and Wang X. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275 5303 (1997) 1129-1132
31. Cohen G.M. Caspases: the executioners of apoptosis. Biochem. J. 326 Pt 1 (1997) 1-16
32. Park W.H., Han Y.H., Kim S.H., and Kim S.Z. Pyrogallol, ROS generator inhibits As4.1 juxtaglomerular cells via cell cycle arrest of G2 phase and apoptosis. Toxicology 235 1-2 (2007) 130-139
33. Kim S.W., Han Y.W., Lee S.T., Jeong H.J., Kim S.H., Kim I.H., Lee S.O., Kim D.G., Kim S.H., Kim S.Z., and Park W.H. A superoxide anion generator, pyrogallol, inhibits the growth of HeLa cells via cell cycle arrest and apoptosis. Mol. Carcinog. 47 2 (2007) 114-125