-
1
-
-
0345256652
-
Cisplatin: Mode of cytotoxic action and molecular basis of resistance
-
DOI 10.1038/sj.onc.1206933, Drug Resistance
-
Siddik ZH. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 2003;22:7265-79. (Pubitemid 37487159)
-
(2003)
Oncogene
, vol.22
, Issue.47 REV. ISS. 6
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
2
-
-
79955011809
-
N1, N3-Dimethyl-N1,N3-bis(phenylcarbonothioyl) propanedihydrazide (elesclomol) selectively kills cisplatin resistant lung cancer cells through reactive oxygen species (ROS)
-
Basel
-
Wangpaichitr M, Wu C, You M, Maher JC, Dinh V, Feun LG, et al. N1, N3-Dimethyl-N1,N3-bis(phenylcarbonothioyl) propanedihydrazide (elesclomol) selectively kills cisplatin resistant lung cancer cells through reactive oxygen species (ROS). Cancers (Basel) 2009;1:23-8.
-
(2009)
Cancers
, vol.1
, pp. 23-28
-
-
Wangpaichitr, M.1
Wu, C.2
You, M.3
Maher, J.C.4
Dinh, V.5
Feun, L.G.6
-
3
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
DOI 10.1093/emboj/17.9.2596
-
Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 1998;17:2596-606. (Pubitemid 28221195)
-
(1998)
EMBO Journal
, vol.17
, Issue.9
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
4
-
-
54249105017
-
The thioredoxin system mediates redox-induced cell death in human colon cancer cells: Implications for the mechanism of action of anticancer agents
-
Sun Y, Rigas B. The thioredoxin system mediates redox-induced cell death in human colon cancer cells: implications for the mechanism of action of anticancer agents. Cancer Res 2008;68:8269-77.
-
(2008)
Cancer Res
, vol.68
, pp. 8269-8277
-
-
Sun, Y.1
Rigas, B.2
-
5
-
-
23444435104
-
Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds
-
DOI 10.1016/j.freeradbiomed.2005.04.025, PII S0891584905002315
-
Witte AB, Anestal K, Jerremalm E, Ehrsson H, Arner ES. Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds. Free Radic Biol Med 2005;39:696-703. (Pubitemid 41112110)
-
(2005)
Free Radical Biology and Medicine
, vol.39
, Issue.5
, pp. 696-703
-
-
Witte, A.-B.1
Anestal, K.2
Jerremalm, E.3
Ehrsson, H.4
Arner, E.S.J.5
-
6
-
-
0026443077
-
Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway
-
Rubartelli A, Bajetto A, Allavena G, Wollman E, Sitia R. Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway. J Biol Chem 1992;267:24161-4.
-
(1992)
J Biol Chem
, vol.267
, pp. 24161-24164
-
-
Rubartelli, A.1
Bajetto, A.2
Allavena, G.3
Wollman, E.4
Sitia, R.5
-
7
-
-
0028967352
-
High rates of thioredoxin secretion correlate with growth arrest in hepatomacells
-
Rubartelli A, Bonifaci N, Sitia R. High rates of thioredoxin secretion correlate with growth arrest in hepatomacells.Cancer Res 1995;55:675-80.
-
(1995)
Cancer Res
, vol.55
, pp. 675-680
-
-
Rubartelli, A.1
Bonifaci, N.2
Sitia, R.3
-
8
-
-
0346340024
-
Increased Plasma Levels of Thioredoxin in Patients with Coronary Spastic Angina
-
Miyamoto S, Kawano H, Sakamoto T, Soejima H, Kajiwara I, Hokamaki J, et al. Increased plasma levels of thioredoxin in patients with coronary spastic angina. Antioxid Redox Signal 2004;6:75-80. (Pubitemid 38063977)
-
(2004)
Antioxidants and Redox Signaling
, vol.6
, Issue.1
, pp. 75-80
-
-
Miyamoto, S.1
Kawano, H.2
Sakamoto, T.3
Soejima, H.4
Kajiwara, I.5
Hokamaki, J.6
Hirai, N.7
Sugiyama, S.8
Yoshimura, M.9
Yasue, H.10
Nakamura, H.11
Yodoi, J.12
Ogawa, H.13
-
9
-
-
34548067718
-
Thioredoxin signaling as a target for cancer therapy
-
DOI 10.1016/j.coph.2007.04.003, PII S1471489207000914, Cancer/Immunomodulation
-
Powis G, Kirkpatrick DL. Thioredoxin signaling as a target for cancer therapy. Curr Opin Pharmacol 2007;7:392-7. (Pubitemid 47289261)
-
(2007)
Current Opinion in Pharmacology
, vol.7
, Issue.4
, pp. 392-397
-
-
Powis, G.1
Kirkpatrick, D.L.2
-
10
-
-
0034544555
-
Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation
-
Wei SJ, Botero A, Hirota K, Bradbury CM, Markovina S, Laszlo A, et al. Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation. Cancer Res 2000;60:6688-95.
-
(2000)
Cancer Res
, vol.60
, pp. 6688-6695
-
-
Wei, S.J.1
Botero, A.2
Hirota, K.3
Bradbury, C.M.4
Markovina, S.5
Laszlo, A.6
-
11
-
-
48349107170
-
A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity
-
Ando K, Hirao S, Kabe Y, Ogura Y, Sato I, Yamaguchi Y, et al. A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity. Nucleic Acids Res 2008;36:4327-36.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4327-4336
-
-
Ando, K.1
Hirao, S.2
Kabe, Y.3
Ogura, Y.4
Sato, I.5
Yamaguchi, Y.6
-
12
-
-
80051685491
-
Thioredoxin regulates adipogenesis through thioredoxin interacting protein (Txnip) protein stability
-
Chutkow WA, Lee RT. Thioredoxin regulates adipogenesis through thioredoxin interacting protein (Txnip) protein stability. J Biol Chem 2011;286:29139-45.
-
(2011)
J Biol Chem
, vol.286
, pp. 29139-29145
-
-
Chutkow, W.A.1
Lee, R.T.2
-
13
-
-
48749099976
-
Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and anti-apoptotic proteins
-
Wangpaichitr M, Wu C, You M, Kuo MT, Feun L, Lampidis T, et al. Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and anti-apoptotic proteins. Eur J Pharmacol 2008;591:124-7.
-
(2008)
Eur J Pharmacol
, vol.591
, pp. 124-127
-
-
Wangpaichitr, M.1
Wu, C.2
You, M.3
Kuo, M.T.4
Feun, L.5
Lampidis, T.6
-
14
-
-
26844545448
-
Overcoming cisplatin resistance by mTOR inhibitor in lung cancer
-
Wu C, Wangpaichitr M, Feun L, Kuo MT, Robles C, Lampidis T, et al. Overcoming cisplatin resistance by mTOR inhibitor in lung cancer. Mol Cancer 2005;4:25.
-
(2005)
Mol Cancer
, vol.4
, pp. 25
-
-
Wu, C.1
Wangpaichitr, M.2
Feun, L.3
Kuo, M.T.4
Robles, C.5
Lampidis, T.6
-
15
-
-
1542435945
-
Overexpression of mutated MRP4 in cisplatin resistant small cell lung cancer cell line: Collateral sensitivity to azidothymidine
-
Savaraj N,WuC, Wangpaichitr M, Kuo MT, Lampidis T, Robles C, et al. Overexpression of mutated MRP4 in cisplatin resistant small cell lung cancer cell line: collateral sensitivity to azidothymidine. Int J Oncol 2003;23:173-9.
-
(2003)
Int J Oncol
, vol.23
, pp. 173-179
-
-
Savaraj, N.1
Wu, C.2
Wangpaichitr, M.3
Kuo, M.T.4
Lampidis, T.5
Robles, C.6
-
16
-
-
0029955068
-
Detection of 11q13 amplification as the origin of a homogeneously staining region in small cell lung cancer by chromosome microdissection
-
DOI 10.1002/(SICI)1098-2264(199611)17:3<172::AID-GCC5>3.0.CO;2-1
-
Xu J, Tyan T, Cedrone E, Savaraj N, Wang N. Detection of 11q13 amplification as the origin of a homogeneously staining region in small cell lung cancer by chromosome microdissection. Genes Chromosomes Cancer 1996;17:172-8. (Pubitemid 26418695)
-
(1996)
Genes Chromosomes and Cancer
, vol.17
, Issue.3
, pp. 172-178
-
-
Xu, J.1
Tyan, T.2
Cedrone, E.3
Savaraj, N.4
Wang, N.5
-
17
-
-
49849099471
-
Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines
-
Wangpaichitr M, Savaraj N, Maher J, Kurtoglu M, Lampidis TJ. Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines. Mol Cancer Ther 2008;7:1506-13.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1506-1513
-
-
Wangpaichitr, M.1
Savaraj, N.2
Maher, J.3
Kurtoglu, M.4
Lampidis, T.J.5
-
18
-
-
45549107064
-
Arginine deprivation as a targeted therapy for cancer
-
DOI 10.2174/138161208784246199
-
Feun L, You M, Wu CJ, Kuo MT, Wangpaichitr M, Spector S, et al. Arginine deprivation as a targeted therapy for cancer. Curr Pharm Des 2008;14:1049-57. (Pubitemid 351982554)
-
(2008)
Current Pharmaceutical Design
, vol.14
, Issue.11
, pp. 1049-1057
-
-
Feun, L.1
You, M.2
Wu, C.J.3
Kuo, M.T.4
Wangpaichitr, M.5
Spector, S.6
Savaraj, N.7
-
19
-
-
0027345943
-
A novel way to get out of the cell
-
Rubartelli A, Bajetto A, Bonifaci N, Di Blas E, Solito E, Sitia R. A novel way to get out of the cell. Cytotechnology 1993;11 Suppl 1:S37-40.
-
(1993)
Cytotechnology
, vol.11
, Issue.SUPPL. 1
-
-
Rubartelli, A.1
Bajetto, A.2
Bonifaci, N.3
Di Blas, E.4
Solito, E.5
Sitia, R.6
-
20
-
-
57049167019
-
Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease
-
Huttemann M, Lee I, Pecinova A, Pecina P, Przyklenk K, Doan JW. Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease. J Bioenerg Biomembr 2008;40:445-56.
-
(2008)
J Bioenerg Biomembr
, vol.40
, pp. 445-456
-
-
Huttemann, M.1
Lee, I.2
Pecinova, A.3
Pecina, P.4
Przyklenk, K.5
Doan, J.W.6
-
21
-
-
0004103143
-
Biochemistry: A functional approach
-
Dusseau J, editor. Philadelphia, PA: W.B. Saunders Company
-
McGilvery RW. Biochemistry: a functional approach. In: Dusseau J, editor. Chapter 11: The oxidation of coenzyme A. Philadelphia, PA: W.B. Saunders Company; 1970. p. 206-24.
-
(1970)
Chapter 11: The Oxidation of Coenzyme A
, pp. 206-224
-
-
McGilvery, R.W.1
-
22
-
-
0014917933
-
An eclectic view of metabolic regulation: Control of citrate synthase activity
-
Srere PA. An eclectic view of metabolic regulation: control of citrate synthase activity. Adv Enzyme Regul 1970;9:221-33.
-
(1970)
Adv Enzyme Regul
, vol.9
, pp. 221-233
-
-
Srere, P.A.1
-
23
-
-
0007698077
-
Biosynthesis of urea. VI. Enzymatic cleavage of argininosuccinic acid to arginine and fumaric acid
-
Ratner S, AnslowWPJr, Petrack B. Biosynthesis of urea. VI. Enzymatic cleavage of argininosuccinic acid to arginine and fumaric acid. J Biol Chem 1953;204:115-25.
-
(1953)
J Biol Chem
, vol.204
, pp. 115-125
-
-
Ratner, S.1
Anslow Jr., W.P.2
Petrack, B.3
-
24
-
-
0021715781
-
Inhibition of fatty acid synthesis in isolated adipocytes by 5-(tetradecyloxy)-2-furoic acid
-
DOI 10.1007/BF02534514
-
Halvorson DL, McCune SA. Inhibition of fatty acid synthesis in isolated adipocytes by 5-(tetradecyloxy)-2-furoic acid. Lipids 1984;19:851-6. (Pubitemid 15188497)
-
(1984)
Lipids
, vol.19
, Issue.11
, pp. 851-856
-
-
Halvorson, D.L.1
McCune, S.A.2
-
26
-
-
50449094619
-
Mitochondrial drugs
-
Toogood PL. Mitochondrial drugs. Curr Opin Chem Biol 2008;12:457-63.
-
(2008)
Curr Opin Chem Biol
, vol.12
, pp. 457-463
-
-
Toogood, P.L.1
-
27
-
-
33846856501
-
Phase I clinical trial of STA-4783 in combination with paclitaxel in patients with refractory solid tumors
-
DOI 10.1158/1078-0432.CCR-06-0964
-
Berkenblit A, Eder JP Jr, Ryan DP, Seiden MV, Tatsuta N, Sherman ML, et al. Phase I clinical trial of STA-4783 in combination with paclitaxel in patients with refractory solid tumors. Clin Cancer Res 2007;13:584-90. (Pubitemid 46225365)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.2 I
, pp. 584-590
-
-
Berkenblit, A.1
Eder Jr., J.P.2
Ryan, D.P.3
Seiden, M.V.4
Tatsuta, N.5
Sherman, M.L.6
Dahl, T.A.7
Dezube, B.J.8
Supko, J.G.9
-
28
-
-
73949153317
-
Phase II, randomized, controlled, double-blinded trial of weekly elesclomol plus paclitaxel versus paclitaxel alone for stage IV metastatic melanoma
-
O'Day S, Gonzalez R, Lawson D, Weber R, Hutchins L, Anderson C, et al. Phase II, randomized, controlled, double-blinded trial of weekly elesclomol plus paclitaxel versus paclitaxel alone for stage IV metastatic melanoma. J Clin Oncol 2009;27:5452-8.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5452-5458
-
-
O'Day, S.1
Gonzalez, R.2
Lawson, D.3
Weber, R.4
Hutchins, L.5
Anderson, C.6
-
29
-
-
0029928253
-
Elevation of plasma thioredoxin levels in HIV-infected individuals
-
DOI 10.1093/intimm/8.4.603
-
Nakamura H, De Rosa S, Roederer M, Anderson MT, Dubs JG, Yodoi J, et al. Elevation of plasma thioredoxin levels in HIV-infected individuals. Int Immunol 1996;8:603-11. (Pubitemid 26115876)
-
(1996)
International Immunology
, vol.8
, Issue.4
, pp. 603-611
-
-
Nakamura, H.1
De Rosa, S.2
Roederer, M.3
Anderson, M.T.4
Dubs, J.G.5
Yodoi, J.6
Holmgren, A.7
Herzenberg, L.A.8
Herzenberg, L.A.9
-
30
-
-
0032078806
-
Measurements of plasma glutaredoxin and thioredoxin in healthy volunteers and during open-heart surgery
-
DOI 10.1016/S0891-5849(97)00429-2, PII S0891584997004292
-
Nakamura H, Vaage J, Valen G, Padilla CA, Bjornstedt M, Holmgren A. Measurements of plasma glutaredoxin and thioredoxin in healthy volunteers and during open-heart surgery. Free Radic Biol Med 1998;24:1176-86. (Pubitemid 28246731)
-
(1998)
Free Radical Biology and Medicine
, vol.24
, Issue.7-8
, pp. 1176-1186
-
-
Nakamura, H.1
Vaage, J.2
Valen, G.3
Padilla, C.A.4
Bjornstedt, M.5
Holmgren, A.6
-
31
-
-
0034531035
-
Secretion of thioredoxin enhances cellular resistance to cis-diamminedichloroplatinum (II)
-
Sasada T, Nakamura H, Ueda S, Iwata S, Ueno M, Takabayashi A, et al. Secretion of thioredoxin enhances cellular resistance to cis- diamminedichloroplatinum (II). Antioxid Redox Signal 2000;2:695-705. (Pubitemid 32062321)
-
(2000)
Antioxidants and Redox Signaling
, vol.2
, Issue.4
, pp. 695-705
-
-
Sasada, T.1
Nakamura, H.2
Ueda, S.3
Iwata, S.4
Ueno, M.5
Takabayashi, A.6
Yodoi, J.7
-
32
-
-
0032840612
-
Possible involvement of thioredoxin reductase as well as thioredoxin in cellular sensitivity to cis-diamminedichloroplatinum (II)
-
DOI 10.1016/S0891-5849(99)00101-X, PII S089158499900101X
-
Sasada T, Nakamura H, Ueda S, Sato N, Kitaoka Y, Gon Y, et al. Possible involvement of thioredoxin reductase as well as thioredoxin in cellular sensitivity to cis-diamminedichloroplatinum (II). Free Radic Biol Med 1999;27:504-14. (Pubitemid 29408635)
-
(1999)
Free Radical Biology and Medicine
, vol.27
, Issue.5-6
, pp. 504-514
-
-
Sasada, T.1
Nakamura, H.2
Ueda, S.3
Sato, N.4
Kitaoka, Y.5
Gon, Y.6
Takabayashi, A.7
Spyrou, G.8
Holmgren, A.9
Yodoi, J.10
-
33
-
-
50449087893
-
Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1
-
Chen HH, Song IS, Hossain A, Choi MK, Yamane Y, Liang ZD, et al. Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1. Mol Pharmacol 2008;74:697-704.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 697-704
-
-
Chen, H.H.1
Song, I.S.2
Hossain, A.3
Choi, M.K.4
Yamane, Y.5
Liang, Z.D.6
-
34
-
-
33947407250
-
The roles of copper transporters in cisplatin resistance
-
DOI 10.1007/s10555-007-9045-3, Special Issue on Transporters in Cancer
-
Kuo MT, Chen HH, Song IS, Savaraj N, Ishikawa T. The roles of copper transporters in cisplatin resistance. Cancer Metastasis Rev 2007;26:71-83. (Pubitemid 46452185)
-
(2007)
Cancer and Metastasis Reviews
, vol.26
, Issue.1
, pp. 71-83
-
-
Kuo, M.T.1
Chen, H.H.W.2
Song, I.-S.3
Savaraj, N.4
Ishikawa, T.5
-
35
-
-
12344314253
-
Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells
-
Song IS, Savaraj N, Siddik ZH, Liu P, Wei Y,WuCJ, et al. Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells. Mol Cancer Ther 2004;3:1543-9. (Pubitemid 40136709)
-
(2004)
Molecular Cancer Therapeutics
, vol.3
, Issue.12
, pp. 1543-1549
-
-
Song, I.-S.1
Savaraj, N.2
Siddik, Z.H.3
Liu, P.4
Wei, Y.5
Wu, C.J.6
Kuo, M.T.7
-
36
-
-
0036735392
-
The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis
-
Welsh SJ, Bellamy WT, Briehl MM, Powis G. The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis. Cancer Res 2002;62:5089-95. (Pubitemid 34984438)
-
(2002)
Cancer Research
, vol.62
, Issue.17
, pp. 5089-5095
-
-
Welsh, S.J.1
Bellamy, W.T.2
Briehl, M.M.3
Powis, G.4
-
37
-
-
84859412602
-
Metabolic changes associated with acquired cisplatin resistance
-
[abstract]. Abstract nr 4087
-
Sullivan EJ, Kurtoglu M, Wangpaichitr M, Savaraj N, Lampidis T. Metabolic changes associated with acquired cisplatin resistance [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; 2011. Abstract nr 4087.
-
Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; 2011
-
-
Sullivan, E.J.1
Kurtoglu, M.2
Wangpaichitr, M.3
Savaraj, N.4
Lampidis, T.5
-
38
-
-
73149106998
-
Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1alpha/Sp4
-
Tsai WB, Aiba I, Lee SY, Feun L, Savaraj N, Kuo MT. Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1alpha/Sp4. Mol Cancer Ther 2009;8:3223-33.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3223-3233
-
-
Tsai, W.B.1
Aiba, I.2
Lee, S.Y.3
Feun, L.4
Savaraj, N.5
Kuo, M.T.6
-
39
-
-
33846625891
-
Renal cell carcinoma does not express argininosuccinate synthetase and is highly sensitive to arginine deprivation via arginine deiminase
-
Yoon CY, Shim YJ, Kim EH, Lee JH, Won NH, Kim JH, et al. Renal cell carcinoma does not express argininosuccinate synthetase and is highly sensitive to arginine deprivation via arginine deiminase. Int J Cancer 2007;120:897-905.
-
(2007)
Int J Cancer
, vol.120
, pp. 897-905
-
-
Yoon, C.Y.1
Shim, Y.J.2
Kim, E.H.3
Lee, J.H.4
Won, N.H.5
Kim, J.H.6
-
40
-
-
33845761445
-
In vivo loss of expression of argininosuccinate synthetase in malignant pleural mesothelioma is a biomarker for susceptibility to arginine depletion
-
DOI 10.1158/1078-0432.CCR-06-1101
-
Szlosarek PW, Klabatsa A, Pallaska A, Sheaff M, Smith P, Crook T, et al. In vivo loss of expression of argininosuccinate synthetase in malignant pleural mesothelioma is a biomarker for susceptibility to arginine depletion. Clin Cancer Res 2006;12:7126-31. (Pubitemid 44974513)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.23
, pp. 7126-7131
-
-
Szlosarek, P.W.1
Klabatsa, A.2
Pallaska, A.3
Sheaff, M.4
Smith, P.5
Crook, T.6
Grimshaw, M.J.7
Steele, J.P.8
Rudd, R.M.9
Balkwill, F.R.10
Fennell, D.A.11
-
41
-
-
0036792124
-
Pegylated arginine deiminase (ADI-SS PEG20,000 mw) inhibits human melanomas and hepatocellular carcinomas in vitro and in vivo
-
Ensor CM, Holtsberg FW, Bomalaski JS, Clark MA. Pegylated arginine deiminase (ADI-SS PEG20,000 mw) inhibits human melanomas and hepatocellular carcinomas in vitro and in vivo. Cancer Res 2002;62:5443-50.
-
(2002)
Cancer Res
, vol.62
, pp. 5443-5450
-
-
Ensor, C.M.1
Holtsberg, F.W.2
Bomalaski, J.S.3
Clark, M.A.4
-
42
-
-
84859402474
-
Incidence and distribution of argininosuccinate synthetase deficiency in human cancers: A method for identifying cancers sensitive to arginine deprivation by arginine deiminase
-
abstr 968
-
Prieto V, Curley S, Ensor C, Holzberg F, Bomalaski J, Clak M. Incidence and distribution of argininosuccinate synthetase deficiency in human cancers: a method for identifying cancers sensitive to arginine deprivation by arginine deiminase. Proc Am Soc Clin Oncol 22: 2003 (suppl; abstr 968).
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, Issue.SUPPL.
-
-
Prieto, V.1
Curley, S.2
Ensor, C.3
Holzberg, F.4
Bomalaski, J.5
Clak, M.6
-
43
-
-
77953491512
-
Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma
-
Savaraj N, You M, Wu C, Wangpaichitr M, Kuo MT, Feun LG. Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma. Curr Mol Med 2010;10:405-12.
-
(2010)
Curr Mol Med
, vol.10
, pp. 405-412
-
-
Savaraj, N.1
You, M.2
Wu, C.3
Wangpaichitr, M.4
Kuo, M.T.5
Feun, L.G.6
-
44
-
-
32944469353
-
Pegylated arginine deiminase treatment of patients with metastatic melanoma: Results from phase I and II studies
-
DOI 10.1200/JCO.2005.02.0933
-
Ascierto PA, Scala S, Castello G, Daponte A, Simeone E, Ottaiano A, et al. Pegylated arginine deiminase treatment of patients with metastatic melanoma: results from phase I and II studies. J Clin Oncol 2005;23:7660-8. (Pubitemid 46291831)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.30
, pp. 7660-7668
-
-
Ascierto, P.A.1
Scala, S.2
Castello, G.3
Daponte, A.4
Simeone, E.5
Ottaiano, A.6
Beneduce, G.7
De Rosa, V.8
Izzo, F.9
Melucci, M.T.10
Ensor, C.M.11
Prestayko, A.W.12
Holtsberg, F.W.13
Bomalaski, J.S.14
Clark, M.A.15
Savaraj, N.16
Feun, L.G.17
Logan, T.F.18
-
45
-
-
67651204610
-
Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species
-
Sudarshan S, Sourbier C, Kong HS, Block K, Valera Romero VA, Yang Y, et al. Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species. Mol Cell Biol 2009;29:4080-90.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4080-4090
-
-
Sudarshan, S.1
Sourbier, C.2
Kong, H.S.3
Block, K.4
Valera Romero, V.A.5
Yang, Y.6
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