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Volumn 8, Issue 12, 2013, Pages

The transcriptomic response of rat hepatic stellate cells to endotoxin: Implications for hepatic inflammation and immune regulation

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; BACTERIUM LIPOPOLYSACCHARIDE; BETA CHEMOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 17F; MITOGEN ACTIVATED PROTEIN KINASE; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

EID: 84891916013     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082159     Document Type: Article
Times cited : (36)

References (85)
  • 1
    • 67650750880 scopus 로고    scopus 로고
    • The liver as a lymphoid organ
    • doi:10.1146/annurev. immunol.021908.132629, PubMed: 19302037
    • Crispe IN (2009) The liver as a lymphoid organ. Annu Rev Immunol 27:147-163. doi:10.1146/annurev. immunol.021908.132629. PubMed: 19302037.
    • (2009) Annu Rev Immunol , vol.27 , pp. 147-163
    • Crispe, I.N.1
  • 2
    • 77958557979 scopus 로고    scopus 로고
    • Antigen-presenting cell function in the tolerogenic liver environment
    • doi: 10.1038/nri2858, PubMed: 20972472
    • Thomson AW, Knolle PA (2010) Antigen-presenting cell function in the tolerogenic liver environment. Nat Rev Immunol 10:753-766. doi: 10.1038/nri2858. PubMed: 20972472.
    • (2010) Nat Rev Immunol , vol.10 , pp. 753-766
    • Thomson, A.W.1    Knolle, P.A.2
  • 3
    • 0035165909 scopus 로고    scopus 로고
    • Immunology of the healthy liver: Old questions and new insights
    • Mehal WZ, Azzaroli F, Crispe IN (2001) Immunology of the healthy liver: old questions and new insights. Gastroenterology 120:250-260. doi:10.1053/gast.2001.20947. PubMed: 11208734. (Pubitemid 32061889)
    • (2001) Gastroenterology , vol.120 , Issue.1 , pp. 250-260
    • Mehal, W.Z.1    Azzaroli, F.2    Crispe, I.N.3
  • 5
    • 0037270978 scopus 로고    scopus 로고
    • Hepatic T cells and liver tolerance
    • DOI 10.1038/nri981
    • Crispe IN (2003) Hepatic T cells and liver tolerance. Nat Rev Immunol 3:51-62. doi:10.1038/nri981. PubMed: 12511875. (Pubitemid 37328699)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.1 , pp. 51-62
    • Crispe, I.N.1
  • 6
    • 0014661390 scopus 로고
    • Induction of immunological tolerance by porcine liver allografts
    • doi:10.1038/223472a0, PubMed: 4894426
    • Calne RY, Sells RA, Pena JR, Davis DR, Millard PR et al. (1969) Induction of immunological tolerance by porcine liver allografts. Nature 223:472-476. doi:10.1038/223472a0. PubMed: 4894426.
    • (1969) Nature , vol.223 , pp. 472-476
    • Calne, R.Y.1    Sells, R.A.2    Pena, J.R.3    Davis, D.R.4    Millard, P.R.5
  • 7
    • 0028297988 scopus 로고
    • Murine liver allograft transplantation: Tolerance and donor cell chimerism
    • DOI 10.1016/0270-9139(94)90292-5
    • Qian S, Demetris AJ, Murase N, Rao AS, Fung JJ et al. (1994) Murine liver allograft transplantation: tolerance and donor cell chimerism. Hepatology 19:916-924. doi:10.1002/hep. 1840190418. PubMed: 8138266. (Pubitemid 24109354)
    • (1994) Hepatology , vol.19 , Issue.4 , pp. 916-924
    • Qian, S.1    Demetris, A.J.2    Murase, N.3    Rao, A.S.4    Fung, J.J.5    Starzl, T.E.6
  • 8
    • 0025118742 scopus 로고
    • Liver transplantation across ABO blood group barriers
    • DOI 10.1016/0140-6736(90)92082-S
    • Gugenheim J, Samuel D, Reynes M, Bismuth H (1990) Liver transplantation across ABO blood group barriers. Lancet 336:519-523. doi:10.1016/0140-6736 (90) 92082-S. PubMed: 1975036. (Pubitemid 20278096)
    • (1990) Lancet , vol.336 , Issue.8714 , pp. 519-523
    • Gugenheim, J.1    Samuel, D.2    Reynes, M.3    Bismuth, H.4
  • 11
    • 78650424492 scopus 로고    scopus 로고
    • Immunologic basis of graft rejection and tolerance following transplantation of liver or other solid organs
    • doi:10.1053/j.gastro. 2010.10.059, PubMed: 21073873
    • Sanchez-Fueyo A, Strom TB (2011) Immunologic basis of graft rejection and tolerance following transplantation of liver or other solid organs. Gastroenterology 140:51-64. doi:10.1053/j.gastro. 2010.10.059. PubMed: 21073873.
    • (2011) Gastroenterology , vol.140 , pp. 51-64
    • Sanchez-Fueyo, A.1    Strom, T.B.2
  • 12
    • 84855993116 scopus 로고    scopus 로고
    • Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants
    • doi:10.1001/jama.2011.2014, PubMed: 22253395
    • Feng S, Ekong UD, Lobritto SJ, Demetris AJ, Roberts JP et al. (2012) Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants. JAMA 307:283-293. doi:10.1001/jama.2011.2014. PubMed: 22253395.
    • (2012) JAMA , vol.307 , pp. 283-293
    • Feng, S.1    Ekong, U.D.2    Lobritto, S.J.3    Demetris, A.J.4    Roberts, J.P.5
  • 13
    • 84891944554 scopus 로고    scopus 로고
    • Stellate cells. In molecular pathology of liver diseases
    • Springer
    • Gandhi CR (2011) Stellate Cells. In Molecular Pathology of Liver Diseases. In. SP Monga. Springer. pp. 53-80.
    • (2011) SP Monga , pp. 53-80
    • Gandhi, C.R.1
  • 14
    • 21644434942 scopus 로고    scopus 로고
    • Normal rat hepatic stellate cells respond to endotoxin in LBP-independent manner to produce inhibitor(s) of DNA synthesis in hepatocytes
    • DOI 10.1002/jcp.20366
    • Thirunavukkarasu C, Uemura T, Wang LF, Watkins SC, Gandhi CR (2005) Normal rat hepatic stellate cells respond to endotoxin in LBPindependent manner to produce inhibitor (s) of DNA synthesis in hepatocytes. J Cell Physiol 204:654-665. doi:10.1002/jcp. 20366. PubMed: 15828022. (Pubitemid 40934662)
    • (2005) Journal of Cellular Physiology , vol.204 , Issue.2 , pp. 654-665
    • Thirunavukkarasu, C.1    Uemura, T.2    Wang, L.F.3    Watkins, S.C.4    Gandhi, C.R.5
  • 15
    • 0033774410 scopus 로고    scopus 로고
    • Endotoxin causes upregulation of endothelin receptors in cultured hepatic stellate cells via nitric oxide-dependent and -independent mechanisms
    • doi:10.1038/sj.bjp. 0703577, PubMed: 10991926
    • Gandhi CR, Uemura T, Kuddus RH (2000) Endotoxin causes upregulation of endothelin receptors in cultured hepatic stellate cells via nitric oxide-dependent and -independent mechanisms. Br J Pharmacol 131:319-327. doi:10.1038/sj.bjp. 0703577. PubMed: 10991926.
    • (2000) Br J Pharmacol , vol.131 , pp. 319-327
    • Gandhi, C.R.1    Uemura, T.2    Kuddus, R.H.3
  • 16
    • 0034888217 scopus 로고    scopus 로고
    • Inhibition of DNA synthesis in cultured hepatocytes by endotoxin-conditioned medium of activated stellate cells is transforming growth factor-β and nitric oxide-independent
    • Uemura T, Gandhi CR (2001) Inhibition of DNA synthesis in cultured hepatocytes by endotoxin-conditioned medium of activated stellate cells is transforming growth factor-β- and nitric oxide-independent. Br J Pharmacol 133:1125-1133. doi:10.1038/sj.bjp. 0704151. PubMed: 11487524. (Pubitemid 32762424)
    • (2001) British Journal of Pharmacology , vol.133 , Issue.7 , pp. 1125-1133
    • Uemura, T.1    Gandhi, C.R.2
  • 17
    • 33747075792 scopus 로고    scopus 로고
    • Mechanisms of endotoxin-induced NO, IL-6, and TNF-α production in activated rat hepatic stellate cells: Role of p38 MAPK
    • DOI 10.1002/hep.21254
    • Thirunavukkarasu C, Watkins SC, Gandhi CR (2006) Mechanisms of endotoxin-induced nitric oxide, interleukin-6 and tumor necrosis factor-a production in activated rat hepatic stellate cells: role of p38MAPK. Hepatology 44:389-398. doi:10.1002/hep. 21254. PubMed: 16871588. (Pubitemid 44214878)
    • (2006) Hepatology , vol.44 , Issue.2 , pp. 389-398
    • Thirunavukkarasu, C.1    Watkins, S.C.2    Gandhi, C.R.3
  • 19
    • 84860318483 scopus 로고    scopus 로고
    • Selective expansion of allogeneic regulatory T cells by hepatic stellate cells: Role of endotoxin and implications for allograft tolerance
    • doi:10.4049/jimmunol.1102460, PubMed: 22427640
    • Dangi A, Sumpter TL, Kimura S, Stolz DB, Murase N et al. (2012) Selective expansion of allogeneic regulatory T cells by hepatic stellate cells: role of endotoxin and implications for allograft tolerance. J Immunol 188:3667-3677. doi:10.4049/jimmunol.1102460. PubMed: 22427640.
    • (2012) J Immunol , vol.188 , pp. 3667-3677
    • Dangi, A.1    Sumpter, T.L.2    Kimura, S.3    Stolz, D.B.4    Murase, N.5
  • 20
    • 84867298004 scopus 로고    scopus 로고
    • Hepatic stellate cells undermine the allostimulatory function of liver myeloid dendritic cells via STAT3-dependent induction of IDO
    • doi:10.4049/jimmunol.1200819, PubMed: 22962681
    • Sumpter TL, Dangi A, Matta BM, Huang C, Stolz DB et al. (2012) Hepatic stellate cells undermine the allostimulatory function of liver myeloid dendritic cells via STAT3-dependent induction of IDO. J Immunol 189:3848-3858. doi:10.4049/jimmunol.1200819. PubMed: 22962681.
    • (2012) J Immunol , vol.189 , pp. 3848-3858
    • Sumpter, T.L.1    Dangi, A.2    Matta, B.M.3    Huang, C.4    Stolz, D.B.5
  • 21
    • 58649089811 scopus 로고    scopus 로고
    • Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver
    • doi:10.1053/j.gastro. 2008.10.020, PubMed: 19010327
    • Holt AP, Haughton EL, Lalor PF, Filer A, Buckley CD et al. (2009) Liver myofibroblasts regulate infiltration and positioning of lymphocytes in human liver. Gastroenterology 136:705-714. doi:10.1053/j.gastro. 2008.10.020. PubMed: 19010327.
    • (2009) Gastroenterology , vol.136 , pp. 705-714
    • Holt, A.P.1    Haughton, E.L.2    Lalor, P.F.3    Filer, A.4    Buckley, C.D.5
  • 22
    • 34547751351 scopus 로고    scopus 로고
    • Oral tolerance: Is it all retinoic acid?
    • DOI 10.1084/jem.20071251
    • Von Boehmer H (2007) Oral tolerance: is it all retinoic acid? J Exp Med 204:1737-1739. doi:10.1084/jem.20071251. PubMed: 17620364. (Pubitemid 47236311)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.8 , pp. 1737-1739
    • Von Boehmer, H.1
  • 23
    • 67649311620 scopus 로고    scopus 로고
    • Gut homing receptors on CD8 T cells are retinoic acid dependent and not maintained by liver dendritic or stellate cells
    • doi:10.1053/j.gastro.2009.02.046, PubMed: 19233184
    • Eksteen B, Mora JR, Haughton EL, Henderson NC, Lee-Turner L et al. (2009) Gut homing receptors on CD8 T cells are retinoic acid dependent and not maintained by liver dendritic or stellate cells. Gastroenterology 137:320-329. doi:10.1053/j.gastro.2009.02.046. PubMed: 19233184.
    • (2009) Gastroenterology , vol.137 , pp. 320-329
    • Eksteen, B.1    Mora, J.R.2    Haughton, E.L.3    Henderson, N.C.4    Lee-Turner, L.5
  • 25
    • 10644293881 scopus 로고    scopus 로고
    • Inhibition of T-cell responses by hepatic stellate cells via B7-H1-mediated T-cell apoptosis in mice
    • DOI 10.1002/hep.20488
    • Yu MC, Chen CH, Liang X, Wang L, Gandhi CR et al. (2004) Inhibition of T-cell responses by hepatic stellate cells via B7-H1-mediated T-cell apoptosis in mice. Hepatology 40:1312-1321. doi:10.1002/hep. 20488. PubMed: 15565659. (Pubitemid 39657005)
    • (2004) Hepatology , vol.40 , Issue.6 , pp. 1312-1321
    • Yu, M.-C.1    Chen, C.-H.2    Liang, X.3    Wang, L.4    Gandhi, C.R.5    Fung, J.J.6    Lu, L.7    Qian, S.8
  • 26
    • 79959555074 scopus 로고    scopus 로고
    • Murine hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism
    • doi:10.1016/S0168-8278 11 60650-8, PubMed: 21488077
    • Schildberg FA, Wojtalla A, Siegmund SV, Endl E, Diehl L et al. (2011) Murine hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism. Hepatology 54:262-272. doi:10.1016/S0168-8278 (11) 60650-8. PubMed: 21488077.
    • (2011) Hepatology , vol.54 , pp. 262-272
    • Schildberg, F.A.1    Wojtalla, A.2    Siegmund, S.V.3    Endl, E.4    Diehl, L.5
  • 27
    • 78649566446 scopus 로고    scopus 로고
    • B7-H4 mediates inhibition of T cell responses by activated murine hepatic stellate cells
    • doi:10.1002/hep. 23953, PubMed: 21064155
    • Chinnadurai R, Grakoui A (2010) B7-H4 mediates inhibition of T cell responses by activated murine hepatic stellate cells. Hepatology 52:2177-2185. doi:10.1002/hep. 23953. PubMed: 21064155.
    • (2010) Hepatology , vol.52 , pp. 2177-2185
    • Chinnadurai, R.1    Grakoui, A.2
  • 28
    • 58149355299 scopus 로고    scopus 로고
    • Hepatic stellate cells preferentially expand allogeneic CD4+ CD25+ FoxP3+ regulatory T cells in an IL-2-dependent manner
    • doi:10.1097/TP.0b013e31818bfd13, PubMed: 19077880
    • Jiang G, Yang HR, Wang L, Wildey GM, Fung J et al. (2008) Hepatic stellate cells preferentially expand allogeneic CD4+ CD25+ FoxP3+ regulatory T cells in an IL-2-dependent manner. Transplantation 86:1492-1502. doi:10.1097/TP.0b013e31818bfd13. PubMed: 19077880.
    • (2008) Transplantation , vol.86 , pp. 1492-1502
    • Jiang, G.1    Yang, H.R.2    Wang, L.3    Wildey, G.M.4    Fung, J.5
  • 29
    • 79956222106 scopus 로고    scopus 로고
    • Hepatic stellate cells function as regulatory bystanders
    • doi:10.4049/jimmunol.1003917, PubMed: 21460203
    • Ichikawa S, Mucida D, Tyznik AJ, Kronenberg M, Cheroutre H (2011) Hepatic stellate cells function as regulatory bystanders. J Immunol 186:5549-5555. doi:10.4049/jimmunol.1003917. PubMed: 21460203.
    • (2011) J Immunol , vol.186 , pp. 5549-5555
    • Ichikawa, S.1    Mucida, D.2    Tyznik, A.J.3    Kronenberg, M.4    Cheroutre, H.5
  • 30
    • 84892499060 scopus 로고    scopus 로고
    • A novel mouse model of depletion of stellate cells clarifies their role in ischemia/reperfusion- and endotoxin-induced acute liver injury
    • In the press
    • Stewart R, Dangi A, Huang C, Murase N, Kimura S et al. (2013) A novel mouse model of depletion of stellate cells clarifies their role in ischemia/reperfusion- and endotoxin-induced acute liver injury. J Hepatol (In the press).
    • (2013) J Hepatol
    • Stewart, R.1    Dangi, A.2    Huang, C.3    Murase, N.4    Kimura, S.5
  • 31
    • 66349110620 scopus 로고    scopus 로고
    • Toll-like receptors as targets in chronic liver diseases
    • doi:10.1136/gut.2008.156307, PubMed: 19359436
    • Mencin A, Kluwe J, Schwabe RF (2009) Toll-like receptors as targets in chronic liver diseases. Gut 58:704-720. doi:10.1136/gut.2008.156307. PubMed: 19359436.
    • (2009) Gut , vol.58 , pp. 704-720
    • Mencin, A.1    Kluwe, J.2    Schwabe, R.F.3
  • 32
    • 0038185316 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
    • DOI 10.1053/jhep.2003.50182
    • Paik YH, Schwabe RF, Bataller R, Russo MP, Jobin C et al. (2003) Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology 37:1043-1055. doi:10.1053/jhep. 2003.50182. PubMed: 12717385. (Pubitemid 36538681)
    • (2003) Hepatology , vol.37 , Issue.5 , pp. 1043-1055
    • Paik, Y.-H.1    Schwabe, R.F.2    Bataller, R.3    Russo, M.P.4    Jobin, C.5    Brenner, D.A.6
  • 35
    • 80054073999 scopus 로고    scopus 로고
    • TLR7 and TLR8 gene variations and susceptibility to hepatitis C virus infection
    • doi:10.1371/journal.pone.0026235, PubMed: 22022576
    • Wang CH, Eng HL, Lin KH, Chang CH, Hsieh CA et al. (2011) TLR7 and TLR8 gene variations and susceptibility to hepatitis C virus infection. PLOS ONE 6:e26235. doi:10.1371/journal.pone.0026235. PubMed: 22022576.
    • (2011) PLOS ONE , vol.6
    • Wang, C.H.1    Eng, H.L.2    Lin, K.H.3    Chang, C.H.4    Hsieh, C.A.5
  • 36
    • 79953161576 scopus 로고    scopus 로고
    • Hepatitis C virus RNA replication in human stellate cells regulates gene expression of extracellular matrix-related molecules
    • doi:10.1016/j.bbrc.2011.02.125, PubMed: 21371436
    • Watanabe N, Aizaki H, Matsuura T, Kojima S, Wakita T et al. (2011) Hepatitis C virus RNA replication in human stellate cells regulates gene expression of extracellular matrix-related molecules. Biochem Biophys Res Commun 407:135-140. doi:10.1016/j.bbrc.2011.02.125. PubMed: 21371436.
    • (2011) Biochem Biophys Res Commun , vol.407 , pp. 135-140
    • Watanabe, N.1    Aizaki, H.2    Matsuura, T.3    Kojima, S.4    Wakita, T.5
  • 38
    • 84874488611 scopus 로고    scopus 로고
    • Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptorinduced TIMP-1 gene transcription in hepatic stellate cells in mice
    • doi:10.1002/hep. 26108, PubMed: 23080298
    • Perugorria MJ, Murphy LB, Fullard N, Chakraborty JB, Vyrla D et al. (2013) Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptorinduced TIMP-1 gene transcription in hepatic stellate cells in mice. Hepatology 57:1238-1249. doi:10.1002/hep. 26108. PubMed: 23080298.
    • (2013) Hepatology , vol.57 , pp. 1238-1249
    • Perugorria, M.J.1    Murphy, L.B.2    Fullard, N.3    Chakraborty, J.B.4    Vyrla, D.5
  • 39
    • 33745382457 scopus 로고    scopus 로고
    • Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62
    • DOI 10.1016/j.febslet.2006.06.004, PII S001457930600706X
    • Stafford MJ, Morrice NA, Peggie MW, Cohen P (2006) Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62. FEBS Lett 580:4010-4014. doi: 10.1016/j.febslet.2006.06. 004. PubMed: 16806191. (Pubitemid 43946869)
    • (2006) FEBS Letters , vol.580 , Issue.16 , pp. 4010-4014
    • Stafford, M.J.1    Morrice, N.A.2    Peggie, M.W.3    Cohen, P.4
  • 40
    • 0037119996 scopus 로고    scopus 로고
    • Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals
    • doi: 10.1093/emboj/cdf478, PubMed: 12234923
    • Eliopoulos AG, Dumitru CD, Wang CC, Cho J, Tsichlis PN (2002) Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals. EMBO J 21:4831-4840. doi: 10.1093/emboj/cdf478. PubMed: 12234923.
    • (2002) EMBO J , vol.21 , pp. 4831-4840
    • Eliopoulos, A.G.1    Dumitru, C.D.2    Wang, C.C.3    Cho, J.4    Tsichlis, P.N.5
  • 41
    • 58249087316 scopus 로고    scopus 로고
    • BCL11B enhances TCR/CD28-triggered NF-kappaB activation through up-regulation of Cot kinase gene expression in T-lymphocytes
    • Cismasiu VB, Duque J, Paskaleva E, Califano D, Ghanta S et al. (2009) BCL11B enhances TCR/CD28-triggered NF-kappaB activation through up-regulation of Cot kinase gene expression in T-lymphocytes. Biochem J 417:457-466
    • (2009) Biochem J , vol.417 , pp. 457-466
    • Cismasiu, V.B.1    Duque, J.2    Paskaleva, E.3    Califano, D.4    Ghanta, S.5
  • 42
    • 79957553362 scopus 로고    scopus 로고
    • Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: Implications for NO synthase 2 expression
    • doi:10.1002/eji.201041101, PubMed: 21469113
    • Lopez-Pelaez M, Soria-Castro I, Bosca L, Fernandez M, Alemany S (2011) Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: Implications for NO synthase 2 expression. Eur J Immunol 41:1733-1741. doi:10.1002/eji.201041101. PubMed: 21469113.
    • (2011) Eur J Immunol , vol.41 , pp. 1733-1741
    • Lopez-Pelaez, M.1    Soria-Castro, I.2    Bosca, L.3    Fernandez, M.4    Alemany, S.5
  • 44
    • 65949106130 scopus 로고    scopus 로고
    • Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation
    • doi:10.1038/nature07774, PubMed: 19407801
    • Aouadi M, Tesz GJ, Nicoloro SM, Wang M, Chouinard M et al. (2009) Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation. Nature 458:1180-1184. doi:10.1038/nature07774. PubMed: 19407801.
    • (2009) Nature , vol.458 , pp. 1180-1184
    • Aouadi, M.1    Tesz, G.J.2    Nicoloro, S.M.3    Wang, M.4    Chouinard, M.5
  • 45
    • 0037669054 scopus 로고    scopus 로고
    • IκB-ζ, a new anti-inflammatory nuclear protein induced by lipopolysaccharide, is a negative regulator for nuclear factor-κB
    • DOI 10.1179/096805103125001612
    • Muta T, Yamazaki S, Eto A, Motoyama M, Takeshige K (2003) IkappaB-zeta, a new anti-inflammatory nuclear protein induced by lipopolysaccharide, is a negative regulator for nuclear factor-kappaB. J Endotoxin Res 9:187-191. doi:10.1177/09680519030090030801. PubMed: 12831461. (Pubitemid 36722599)
    • (2003) Journal of Endotoxin Research , vol.9 , Issue.3 , pp. 187-191
    • Muta, T.1    Yamazaki, S.2    Eto, A.3    Motoyama, M.4    Takeshige, K.5
  • 46
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • doi:10.1038/ni.1863, PubMed: 20404851
    • Kawai T, Akira S (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11:373-384. doi:10.1038/ni.1863. PubMed: 20404851.
    • (2010) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 47
    • 84865564349 scopus 로고    scopus 로고
    • Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice
    • Kong X, Feng D, Wang H, Hong F, Bertola A et al. (2012) Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice. Hepatology 56:1150-1159.
    • (2012) Hepatology , vol.56 , pp. 1150-1159
    • Kong, X.1    Feng, D.2    Wang, H.3    Hong, F.4    Bertola, A.5
  • 48
    • 82455174787 scopus 로고    scopus 로고
    • Adiponectin inhibits leptin signalling via multiple mechanisms to exert protective effects against hepatic fibrosis
    • doi: 10.1042/BJ20102148, PubMed: 21846328
    • Handy JA, Fu PP, Kumar P, Mells JE, Sharma S et al. (2011) Adiponectin inhibits leptin signalling via multiple mechanisms to exert protective effects against hepatic fibrosis. Biochem J 440:385-395. doi: 10.1042/BJ20102148. PubMed: 21846328.
    • (2011) Biochem J , vol.440 , pp. 385-395
    • Handy, J.A.1    Fu, P.P.2    Kumar, P.3    Mells, J.E.4    Sharma, S.5
  • 49
    • 33847176982 scopus 로고    scopus 로고
    • Inhibitory effects of interferon-gamma on activation of rat pancreatic stellate cells are mediated by STAT1 and involve down-regulation of CTGF expression
    • doi:10.1016/j.cellsig. 2006.10.002, PubMed: 17116388
    • Fitzner B, Brock P, Nechutova H, Glass A, Karopka T et al. (2007) Inhibitory effects of interferon-gamma on activation of rat pancreatic stellate cells are mediated by STAT1 and involve down-regulation of CTGF expression. Cell Signal 19:782-790. doi:10.1016/j.cellsig. 2006.10.002. PubMed: 17116388.
    • (2007) Cell Signal , vol.19 , pp. 782-790
    • Fitzner, B.1    Brock, P.2    Nechutova, H.3    Glass, A.4    Karopka, T.5
  • 50
    • 81155151818 scopus 로고    scopus 로고
    • Role of the mTOR pathway in LPS-activated monocytes: Influence of hypertonic saline
    • doi:10.1016/j.jss. 2010.05.035, PubMed: 20828737
    • Schaeffer V, Arbabi S, Garcia IA, Knoll ML, Cuschieri J et al. (2011) Role of the mTOR pathway in LPS-activated monocytes: influence of hypertonic saline. J Surg Res 171:769-776. doi:10.1016/j.jss. 2010.05.035. PubMed: 20828737.
    • (2011) J Surg Res , vol.171 , pp. 769-776
    • Schaeffer, V.1    Arbabi, S.2    Garcia, I.A.3    Knoll, M.L.4    Cuschieri, J.5
  • 51
    • 67349217332 scopus 로고    scopus 로고
    • Rapamycin enhances LPS induction of tissue factor and tumor necrosis factoralpha expression in macrophages by reducing IL-10 expression
    • doi:10.1016/j.molimm.2009.04.011, PubMed: 19447494
    • Baker AK, Wang R, Mackman N, Luyendyk JP (2009) Rapamycin enhances LPS induction of tissue factor and tumor necrosis factoralpha expression in macrophages by reducing IL-10 expression. Mol Immunol 46:2249-2255. doi:10.1016/j.molimm.2009.04.011. PubMed: 19447494.
    • (2009) Mol Immunol , vol.46 , pp. 2249-2255
    • Baker, A.K.1    Wang, R.2    Mackman, N.3    Luyendyk, J.P.4
  • 52
    • 84860341356 scopus 로고    scopus 로고
    • Inhibition of mammalian target of rapamycin augments lipopolysaccharide- induced lung injury and apoptosis
    • doi:10.4049/jimmunol.1003655, PubMed: 22450807
    • Fielhaber JA, Carroll SF, Dydensborg AB, Shourian M, Triantafillopoulos A et al. (2012) Inhibition of mammalian target of rapamycin augments lipopolysaccharide-induced lung injury and apoptosis. J Immunol 188:4535-4542. doi:10.4049/jimmunol.1003655. PubMed: 22450807.
    • (2012) J Immunol , vol.188 , pp. 4535-4542
    • Fielhaber, J.A.1    Carroll, S.F.2    Dydensborg, A.B.3    Shourian, M.4    Triantafillopoulos, A.5
  • 53
    • 84857395835 scopus 로고    scopus 로고
    • Resveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells
    • doi:10.1371/journal.pone.0032195, PubMed: 22363816
    • Zhong LM, Zong Y, Sun L, Guo JZ, Zhang W et al. (2012) Resveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells. PLOS ONE 7:e32195. doi:10.1371/journal.pone.0032195. PubMed: 22363816.
    • (2012) PLOS ONE , vol.7
    • Zhong, L.M.1    Zong, Y.2    Sun, L.3    Guo, J.Z.4    Zhang, W.5
  • 54
    • 0031972755 scopus 로고    scopus 로고
    • Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells
    • DOI 10.1074/jbc.273.1.302
    • Wang SC, Ohata M, Schrum L, Rippe RA, Tsukamoto H (1998) Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells. J Biol Chem 273:302-308. doi:10.1074/jbc.273.1.302. PubMed: 9417080. (Pubitemid 28042209)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.1 , pp. 302-308
    • Wang, S.C.1    Ohata, M.2    Schrum, L.3    Rippe, R.A.4    Tsukamoto, H.5
  • 55
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • DOI 10.1016/j.immuni.2004.08.018, PII S1074761304002717
    • Kolls JK, Linden A (2004) Interleukin-17 family members and inflammation. Immunity 21:467-476. doi:10.1016/j.immuni. 2004.08.018. PubMed: 15485625. (Pubitemid 39370503)
    • (2004) Immunity , vol.21 , Issue.4 , pp. 467-476
    • Kolls, J.K.1    Linden, A.2
  • 56
    • 84865461464 scopus 로고    scopus 로고
    • Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice
    • Meng F, Wang K, Aoyama T, Grivennikov SI, Paik Y et al. (2012) Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice. Gastroenterology 143:765-776.
    • (2012) Gastroenterology , vol.143 , pp. 765-776
    • Meng, F.1    Wang, K.2    Aoyama, T.3    Grivennikov, S.I.4    Paik, Y.5
  • 57
    • 0035887627 scopus 로고    scopus 로고
    • Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production
    • Starnes T, Robertson MJ, Sledge G, Kelich S, Nakshatri H et al. (2001) Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production. J Immunol 167:4137-4140. PubMed: 11591732. (Pubitemid 32954284)
    • (2001) Journal of Immunology , vol.167 , Issue.8 , pp. 4137-4140
    • Starnes, T.1    Robertson, M.J.2    Sledge, G.3    Kelich, S.4    Nakshatri, H.5    Broxmeyer, H.E.6    Hromas, R.7
  • 59
    • 2642574850 scopus 로고    scopus 로고
    • Secretion of inflammatory mediators by isolated rat Kupffer cells: The effect of octreotide
    • DOI 10.1016/j.regpep.2004.03.009, PII S0167011504000813
    • Valatas V, Kolios G, Manousou P, Xidakis C, Notas G et al. (2004) Secretion of inflammatory mediators by isolated rat Kupffer cells: the effect of octreotide. Regul Pept 120:215-225. doi:10.1016/j.regpep. 2004.03.009. PubMed: 15177940. (Pubitemid 38726210)
    • (2004) Regulatory Peptides , vol.120 , Issue.1-3 , pp. 215-225
    • Valatas, V.1    Kolios, G.2    Manousou, P.3    Xidakis, C.4    Notas, G.5    Ljumovic, D.6    Kouroumalis, E.A.7
  • 60
    • 79955542915 scopus 로고    scopus 로고
    • A diverse range of gene products are effectors of the type I interferon antiviral response
    • doi:10.1038/nature09907, PubMed: 21478870
    • Schoggins JW, Wilson SJ, Panis M, Murphy MY, Jones CT et al. (2011) A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 472:481-485. doi:10.1038/nature09907. PubMed: 21478870.
    • (2011) Nature , vol.472 , pp. 481-485
    • Schoggins, J.W.1    Wilson, S.J.2    Panis, M.3    Murphy, M.Y.4    Jones, C.T.5
  • 61
    • 84865742010 scopus 로고    scopus 로고
    • Interferon regulatory factor-2 is protective against hepatic ischemiareperfusion injury
    • doi:10.1152/ajpgi.00050.2012, PubMed: 22744333
    • Klune JR, Dhupar R, Kimura S, Ueki S, Cardinal J et al. (2012) Interferon regulatory factor-2 is protective against hepatic ischemiareperfusion injury. Am J Physiol Gastrointest Liver Physiol 303:G666-G673. doi:10.1152/ajpgi.00050. 2012. PubMed: 22744333.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.303
    • Klune, J.R.1    Dhupar, R.2    Kimura, S.3    Ueki, S.4    Cardinal, J.5
  • 62
    • 77951456889 scopus 로고    scopus 로고
    • Critical role of interferon regulatory factor-1 in murine liver transplant ischemia reperfusion injury
    • doi:10.1002/hep. 23501, PubMed: 20131404
    • Ueki S, Dhupar R, Cardinal J, Tsung A, Yoshida J et al. (2010) Critical role of interferon regulatory factor-1 in murine liver transplant ischemia reperfusion injury. Hepatology 51:1692-1701. doi:10.1002/hep. 23501. PubMed: 20131404.
    • (2010) Hepatology , vol.51 , pp. 1692-1701
    • Ueki, S.1    Dhupar, R.2    Cardinal, J.3    Tsung, A.4    Yoshida, J.5
  • 63
    • 79952175742 scopus 로고    scopus 로고
    • Interferon regulatory factor 1 mediates acetylation and release of high mobility group box 1 from hepatocytes during murine liver ischemiareperfusion injury
    • doi:10.1097/SHK. 0b013e3181f6aab0, PubMed: 20856174
    • Dhupar R, Klune JR, Evankovich J, Cardinal J, Zhang M et al. (2011) Interferon regulatory factor 1 mediates acetylation and release of high mobility group box 1 from hepatocytes during murine liver ischemiareperfusion injury. Shock 35:293-301. doi:10.1097/SHK. 0b013e3181f6aab0. PubMed: 20856174.
    • (2011) Shock , vol.35 , pp. 293-301
    • Dhupar, R.1    Klune, J.R.2    Evankovich, J.3    Cardinal, J.4    Zhang, M.5
  • 64
    • 21444443078 scopus 로고    scopus 로고
    • Tissue-specific positive feedback requirements for production of type I interferon following virus infection
    • DOI 10.1074/jbc.M501289200
    • Prakash A, Smith E, Lee CK, Levy DE (2005) Tissue-specific positive feedback requirements for production of type I interferon following virus infection. J Biol Chem 280:18651-18657. doi:10.1074/jbc. M501289200. PubMed: 15767254. (Pubitemid 41379565)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.19 , pp. 18651-18657
    • Prakash, A.1    Smith, E.2    Lee, C.-K.3    Levy, D.E.4
  • 65
    • 80052284504 scopus 로고    scopus 로고
    • IRF7: Activation, regulation, modification and function
    • doi:10.1038/gene.2011.21, PubMed: 21490621
    • Ning S, Pagano JS, Barber GN (2011) IRF7: activation, regulation, modification and function. Genes Immun 12:399-414. doi:10.1038/gene.2011.21. PubMed: 21490621.
    • (2011) Genes Immun , vol.12 , pp. 399-414
    • Ning, S.1    Pagano, J.S.2    Barber, G.N.3
  • 67
    • 78049247990 scopus 로고    scopus 로고
    • Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling
    • doi:10.1111/j. 1742-4658.2010.07880.x, PubMed: 20964804
    • Maiwald T, Schneider A, Busch H, Sahle S, Gretz N et al. (2010) Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling. FEBS J 277:4741-4754. doi:10.1111/j. 1742-4658.2010.07880.x. PubMed: 20964804.
    • (2010) FEBS J , vol.277 , pp. 4741-4754
    • Maiwald, T.1    Schneider, A.2    Busch, H.3    Sahle, S.4    Gretz, N.5
  • 68
    • 23744456526 scopus 로고    scopus 로고
    • Interferon-γ up-regulates toll-like receptor 4 and cooperates with lipopolysaccharide to produce macrophage-derived chemokine and interferon-γ inducible protein-10 in human bladder cancer cell line RT4
    • DOI 10.1097/01.ju.0000168619.25341.96
    • Yamada H, Odonnell MA, Matsumoto T, Luo Y (2005) Interferongamma up-regulates toll-like receptor 4 and cooperates with lipopolysaccharide to produce macrophage-derived chemokine and interferon-gamma inducible protein-10 in human bladder cancer cell line RT4. J Urol 174:1119-1123. doi:10.1097/01.ju. 0000168619.25341.96. PubMed: 16094077. (Pubitemid 41140698)
    • (2005) Journal of Urology , vol.174 , Issue.3 , pp. 1119-1123
    • Yamada, H.1    Odonnell, M.A.2    Matsumoto, T.3    Luo, Y.4
  • 71
    • 84855846576 scopus 로고    scopus 로고
    • CCL5 mRNA is a marker for early fibrosis in chronic hepatitis C and is regulated by interferon-α therapy and toll-like receptor 3 signalling
    • doi:10.1111/j.1365-2893.2011.01503.x, PubMed: 22239502
    • Katsounas A, Trippler M, Wang B, Polis M, Lempicki RA et al. (2012) CCL5 mRNA is a marker for early fibrosis in chronic hepatitis C and is regulated by interferon-α therapy and toll-like receptor 3 signalling. J Viral Hepat 19:128-137. doi:10.1111/j.1365-2893.2011.01503.x. PubMed: 22239502.
    • (2012) J Viral Hepat , vol.19 , pp. 128-137
    • Katsounas, A.1    Trippler, M.2    Wang, B.3    Polis, M.4    Lempicki, R.A.5
  • 72
    • 67651156353 scopus 로고    scopus 로고
    • CCR2 promotes hepatic fibrosis in mice
    • doi: 10.1002/hep. 22952, PubMed: 19441102
    • Seki E, De Minicis S, Inokuchi S, Taura K, Miyai K et al. (2009) CCR2 promotes hepatic fibrosis in mice. Hepatology 50:185-197. doi: 10.1002/hep. 22952. PubMed: 19441102.
    • (2009) Hepatology , vol.50 , pp. 185-197
    • Seki, E.1    De Minicis, S.2    Inokuchi, S.3    Taura, K.4    Miyai, K.5
  • 73
    • 0036242256 scopus 로고    scopus 로고
    • Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse
    • DOI 10.1053/jhep.2002.33162
    • Dambach DM, Watson LM, Gray KR, Durham SK, Laskin DL (2002) Role of CCR2 in macrophage migration into the liver during acetaminophen induced hepatotoxicity in the mouse. Hepatology 35:1093-1103. doi:10.1053/jhep. 2002.33162. PubMed: 11981759. (Pubitemid 34454006)
    • (2002) Hepatology , vol.35 , Issue.5 , pp. 1093-1103
    • Dambach, D.M.1    Watson, L.M.2    Gray, K.R.3    Durham, S.K.4    Laskin, D.L.5
  • 76
    • 34548389834 scopus 로고    scopus 로고
    • The role of CXCL16 in immunological liver injury induced by BCG and LPS in mice
    • PubMed: 15850518
    • Xu HB, Gong YP, Jiang ZG, Liu RZ, Xiong SD (2005) The role of CXCL16 in immunological liver injury induced by BCG and LPS in mice. Zhonghua Gan Zang Bing Za Zhi 13:282-285. PubMed: 15850518.
    • (2005) Zhonghua Gan Zang Bing za Zhi , vol.13 , pp. 282-285
    • Xu, H.B.1    Gong, Y.P.2    Jiang, Z.G.3    Liu, R.Z.4    Xiong, S.D.5
  • 77
    • 24144468641 scopus 로고    scopus 로고
    • Direct hepatotoxic effect of KC chemokine in the liver without infiltration of neutrophils
    • Stefanovic L, Brenner DA, Stefanovic B (2005) Direct hepatotoxic effect of KC chemokine in the liver without infiltration of neutrophils. Exp Biol Med (Maywood) 230:573-586. PubMed: 16118408. (Pubitemid 41233157)
    • (2005) Experimental Biology and Medicine , vol.230 , Issue.8 , pp. 573-586
    • Stefanovic, L.1    Brenner, D.A.2    Stefanovic, B.3
  • 78
    • 77955704597 scopus 로고    scopus 로고
    • Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: Implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis
    • doi:10.1002/hep. 23679, PubMed: 20683959
    • Tuyama AC, Hong F, Saiman Y, Wang C, Ozkok D et al. (2010) Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis. Hepatology 52:612-622. doi:10.1002/hep. 23679. PubMed: 20683959.
    • (2010) Hepatology , vol.52 , pp. 612-622
    • Tuyama, A.C.1    Hong, F.2    Saiman, Y.3    Wang, C.4    Ozkok, D.5
  • 79
    • 0033681191 scopus 로고    scopus 로고
    • Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function
    • doi:10.1016/S1074-7613 00 00023-6, PubMed: 10981966
    • Wright GJ, Puklavec MJ, Willis AC, Hoek RM, Sedgwick JD et al. (2000) Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function. Immunity 13:233-242. doi:10.1016/S1074-7613 (00) 00023-6. PubMed: 10981966.
    • (2000) Immunity , vol.13 , pp. 233-242
    • Wright, G.J.1    Puklavec, M.J.2    Willis, A.C.3    Hoek, R.M.4    Sedgwick, J.D.5
  • 81
    • 4344686812 scopus 로고    scopus 로고
    • Structural and functional heterogeneity in the CD200R family of immunoregulatory molecules and their expression at the fetomaternal interface
    • Gorczynski RM, Chen Z, Clark DA, Kai Y, Lee L et al. (2004) Structural and functional heterogeneity in the CD200R family of immunoregulatory molecules and their expression at the feto-maternal interface. Am J Reprod Immunol 52:147-163. doi:10.1111/j.1600-0897.2004.00192.x. PubMed: 15274657. (Pubitemid 39149320)
    • (2004) American Journal of Reproductive Immunology , vol.52 , Issue.2 , pp. 147-163
    • Gorczynski, R.M.1    Chen, Z.2    Clark, D.A.3    Kai, Y.4    Lee, L.5    Nachman, J.6    Wong, S.7    Marsden, P.8
  • 82
    • 78149234844 scopus 로고    scopus 로고
    • Inhibitory effect of human interferon-beta-1a on activated rat and human hepatic stellate cells
    • doi:10.1111/j. 1440-1746.2010.06264.x, PubMed: 21039841
    • Rao HY, Wei L, Wang JH, Fei R, Jiang D (2010) Inhibitory effect of human interferon-beta-1a on activated rat and human hepatic stellate cells. J Gastroenterol Hepatol 25:1777-1184. doi:10.1111/j. 1440-1746.2010.06264.x. PubMed: 21039841.
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. 1777-1184
    • Rao, H.Y.1    Wei, L.2    Wang, J.H.3    Fei, R.4    Jiang, D.5
  • 83
    • 79251554351 scopus 로고    scopus 로고
    • Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity
    • doi:10.1042/BJ20101473, PubMed: 21126233
    • Park I, Han C, Jin S, Lee B, Choi H et al. (2011) Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity. Biochem J 434:171-180. doi:10.1042/BJ20101473. PubMed: 21126233.
    • (2011) Biochem J , vol.434 , pp. 171-180
    • Park, I.1    Han, C.2    Jin, S.3    Lee, B.4    Choi, H.5
  • 84
    • 33747048138 scopus 로고    scopus 로고
    • Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis
    • DOI 10.1002/hep.21268
    • Uchinami H, Seki E, Brenner DA, D'Armiento J (2006) Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis. Hepatology 44:420-429. doi:10.1002/hep. 21268. PubMed: 16871591. (Pubitemid 44214881)
    • (2006) Hepatology , vol.44 , Issue.2 , pp. 420-429
    • Uchinami, H.1    Seki, E.2    Brenner, D.A.3    D'Armiento, J.4
  • 85
    • 34250322265 scopus 로고    scopus 로고
    • A matrix metalloproteinase-9 activation cascade by hepatic stellate cells in trans-differentiation in the three-dimensional extracellular matrix
    • DOI 10.1074/jbc.M700554200
    • Han YP, Yan C, Zhou L, Qin L, Tsukamoto H (2007) A matrix metalloproteinase-9 activation cascade by hepatic stellate cells in trans-differentiation in the three-dimensional extracellular matrix. J Biol Chem 282:12928-12939. doi:10.1074/jbc. M700554200. PubMed: 17322299. (Pubitemid 47100583)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.17 , pp. 12928-12939
    • Han, Y.-P.1    Yan, C.2    Zhou, L.3    Qin, L.4    Tsukamoto, H.5


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