Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-α expression in macrophages by reducing IL-10 expression

Molecular Immunology

Volumn 46, Issue 11-12, 2009, Pages 2249-2255

  Baker, Alyson K ^a   Wang, Ruipeng ^a   Mackman, Nigel ^b   Luyendyk, James P ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; Interleukin 10; Lipopolysaccharide; Mammalian target of rapamycin; Tissue factor

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; INTERLEUKIN 10; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAPAMYCIN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BACTERIAL IMMUNITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ESCHERICHIA COLI; FEMALE; GENE EXPRESSION REGULATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; FEEDBACK, BIOCHEMICAL; FEMALE; GENE EXPRESSION REGULATION; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; SIROLIMUS; THROMBOPLASTIN; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); MAMMALIA; MUS;

EID: 67349217332     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.04.011     Document Type: Article

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