SCOPUS 정보 검색 플랫폼

Organic and Biomolecular Chemistry

Volumn 12, Issue 5, 2014, Pages 765-773

Dimerization of a heat shock protein 90 inhibitor enhances inhibitory activity

(3) Wahyudi, Hendra a Wang, Yao a McAlpine, Shelli R a

a UNIVERSITY OF NEW SOUTH WALES (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; DIMERS; MONOMERS;

HEAT-SHOCK PROTEIN 90; INHIBITORY ACTIVITY; IT FUNCTIONS; MOLECULAR CHAPERONES; TOTAL PROTEIN;

PROTEINS;

HEAT SHOCK PROTEIN 90; MACROCYCLIC COMPOUND; MACROGOL DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DIMERIZATION; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; PROTEIN REFOLDING; SOLUBILITY;

DIMERIZATION; DRUG DESIGN; HSP90 HEAT-SHOCK PROTEINS; MACROCYCLIC COMPOUNDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; POLYETHYLENE GLYCOLS; PROTEIN REFOLDING; SOLUBILITY;

EID: 84891877675 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/c3ob41722k Document Type: Article

Times cited : (7)

References (43)

1
- 0036219609
- L. Neckers Trends Mol. Med. 2002 8 S55 S61
- (2002) Trends Mol. Med. , vol.8
- Neckers, L.¹

2
- 0042855994
- G. Chiosis H. Huezo N. Rosen E. Mimnaugh L. Whitesell L. Neckers Mol. Cancer Ther. 2003 2 123 129
- (2003) Mol. Cancer Ther. , vol.2 , pp. 123-129
- Chiosis, G.¹ Huezo, H.² Rosen, N.³ Mimnaugh, E.⁴ Whitesell, L.⁵ Neckers, L.⁶

3
- 21244462689
- M. G. Hollingshead M. Alley A. M. Burger S. Borgel C. Pacula-Cox H.-H. Fiebig E. A. Sausville Cancer Chemother. Pharmacol. 2005 56 115 125
- (2005) Cancer Chemother. Pharmacol. , vol.56 , pp. 115-125
- Hollingshead, M.G.¹ Alley, M.² Burger, A.M.³ Borgel, S.⁴ Pacula-Cox, C.⁵ Fiebig, H.-H.⁶ Sausville, E.A.⁷

4
- 29544446133
- M. Senju N. Sueoka A. Sato K. Iwanaga Y. Sakao S. Tomimitsu M. Tominaga K. Irie S. Hayashi E. Sueoka J. Cancer Res. Clin. Oncol. 2006 132 150 158
- (2006) J. Cancer Res. Clin. Oncol. , vol.132 , pp. 150-158
- Senju, M.¹ Sueoka, N.² Sato, A.³ Iwanaga, K.⁴ Sakao, Y.⁵ Tomimitsu, S.⁶ Tominaga, M.⁷ Irie, K.⁸ Hayashi, S.⁹ Sueoka, E.¹⁰

5
- 30044440611
- Y.-S. Chang L.-C. Lee F.-C. Sun C.-C. Chao H.-W. Fu Y.-K. Lai J. Cell. Biochem. 2006 97 156 165
- (2006) J. Cell. Biochem. , vol.97 , pp. 156-165
- Chang, Y.-S.¹ Lee, L.-C.² Sun, F.-C.³ Chao, C.-C.⁴ Fu, H.-W.⁵ Lai, Y.-K.⁶

6
- 33846982944
- D. Matei M. Satpathy L. Cao Y.-C. Lai H. Nakshatri D. B. Donner J. Biol. Chem. 2007 282 445 453
- (2007) J. Biol. Chem. , vol.282 , pp. 445-453
- Matei, D.¹ Satpathy, M.² Cao, L.³ Lai, Y.-C.⁴ Nakshatri, H.⁵ Donner, D.B.⁶

7
- 0034957003
- G. Crevel H. Bates H. Huikeshoven S. Cotterill J. Cell Sci. 2001 114 2015 2025
- (2001) J. Cell Sci. , vol.114 , pp. 2015-2025
- Crevel, G.¹ Bates, H.² Huikeshoven, H.³ Cotterill, S.⁴

8
- 84855769773
- J. E. Bohonowych U. Gopal J. S. Isaacs J. Oncol. 2010 2010 412985
- (2010) J. Oncol. , vol.2010 , pp. 412985
- Bohonowych, J.E.¹ Gopal, U.² Isaacs, J.S.³

9
- 1642471825
- S. Takayama J. C. Reed S. Homma Oncogene 2003 22 9041 9047
- (2003) Oncogene , vol.22 , pp. 9041-9047
- Takayama, S.¹ Reed, J.C.² Homma, S.³

10
- 34248187981
- L. Neckers J. Biosci. 2007 32 517 530
- (2007) J. Biosci. , vol.32 , pp. 517-530
- Neckers, L.¹

11
- 0034605446
- C. Jolly R. I. Morimoto J. Natl. Cancer Inst. 2000 92 1564 1572
- (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1564-1572
- Jolly, C.¹ Morimoto, R.I.²

12
- 0033615357
- T. U. Mayer T. M. Kapoor S. J. Haggarty R. W. King S. L. Schreiber T. J. Mitchison Science 1999 286 971 974
- (1999) Science , vol.286 , pp. 971-974
- Mayer, T.U.¹ Kapoor, T.M.² Haggarty, S.J.³ King, R.W.⁴ Schreiber, S.L.⁵ Mitchison, T.J.⁶

13
- 0033593528
- M. Maruya M. Sameshima T. Nemoto I. Yahara J. Mol. Biol. 1999 285 903 907
- (1999) J. Mol. Biol. , vol.285 , pp. 903-907
- Maruya, M.¹ Sameshima, M.² Nemoto, T.³ Yahara, I.⁴

14
- 0028848373
- T. Nemoto Y. Ohara-Nemoto M. Ota T. Takagi K. Yokoyama Eur. J. Biochem. 1995 233 1 8
- (1995) Eur. J. Biochem. , vol.233 , pp. 1-8
- Nemoto, T.¹ Ohara-Nemoto, Y.² Ota, M.³ Takagi, T.⁴ Yokoyama, K.⁵

15
- 64949083563
- F. Koga K. Kihara L. Neckers Anticancer Res. 2009 29 797 807
- (2009) Anticancer Res. , vol.29 , pp. 797-807
- Koga, F.¹ Kihara, K.² Neckers, L.³

16
- 77953576838
- M. V. Powers K. Jones C. Barillari I. Westwood R. L. M. v. Montfort P. Workman Cell Cycle 2010 9 1542 1550
- (2010) Cell Cycle , vol.9 , pp. 1542-1550
- Powers, M.V.¹ Jones, K.² Barillari, C.³ Westwood, I.⁴ Montfort, R.L.M.V.⁵ Workman, P.⁶

17
- 80054995372
- J. D. Eskew T. Sadikot P. Morales A. Duren I. Dunwiddie M. Swink X. Zhang S. Hembruff A. Donnelly R. A. Rajewski B. S. Blagg J. R. Manjarrez R. L. Matts J. M. Holzbeierlein G. A. Vielhauer BMC Cancer 2011 11 468
- (2011) BMC Cancer , vol.11 , pp. 468
- Eskew, J.D.¹ Sadikot, T.² Morales, P.³ Duren, A.⁴ Dunwiddie, I.⁵ Swink, M.⁶ Zhang, X.⁷ Hembruff, S.⁸ Donnelly, A.⁹ Rajewski, R.A.¹⁰ Blagg, B.S.¹¹ Manjarrez, J.R.¹² Matts, R.L.¹³ Holzbeierlein, J.M.¹⁴ Vielhauer, G.A.¹⁵

18
- 77956640526
- R. C. Vasko R. A. Rodriguez C. N. Cunningham V. C. Ardi D. A. Agard S. R. McAlpine ACS Med. Chem. Lett. 2010 1 4 8
- (2010) ACS Med. Chem. Lett. , vol.1 , pp. 4-8
- Vasko, R.C.¹ Rodriguez, R.A.² Cunningham, C.N.³ Ardi, V.C.⁴ Agard, D.A.⁵ McAlpine, S.R.⁶

19
- 84857995559
- V. C. Ardi L. D. Alexander V. A. Johnson S. R. McAlpine ACS Chem. Biol. 2011 6 1357 1366
- (2011) ACS Chem. Biol. , vol.6 , pp. 1357-1366
- Ardi, V.C.¹ Alexander, L.D.² Johnson, V.A.³ McAlpine, S.R.⁴

20
- 2442713927
- 10.1016/j.bmcl.2013.11.059
- J. M. McConnell L. D. Alexander S. R. McAlpine Bioorg. Med. Chem. Lett. 10.1016/j.bmcl.2013.11.059
- Bioorg. Med. Chem. Lett.
- McConnell, J.M.¹ Alexander, L.D.² McAlpine, S.R.³

21
- 23944442706
- C. L. Carroll J. V. C. Johnston A. Kekec J. D. Brown E. Parry J. Cajica I. Medina K. M. Cook R. Corral P.-S. Pan S. R. McAlpine Org. Lett. 2005 7 3481 3484
- (2005) Org. Lett. , vol.7 , pp. 3481-3484
- Carroll, C.L.¹ Johnston, J.V.C.² Kekec, A.³ Brown, J.D.⁴ Parry, E.⁵ Cajica, J.⁶ Medina, I.⁷ Cook, K.M.⁸ Corral, R.⁹ Pan, P.-S.¹⁰ McAlpine, S.R.¹¹

22
- 29144464196
- T. J. Styers R. A. Rodriguez P.-S. Pan S. R. McAlpine Tetrahedron Lett. 2006 47 515 517
- (2006) Tetrahedron Lett. , vol.47 , pp. 515-517
- Styers, T.J.¹ Rodriguez, R.A.² Pan, P.-S.³ McAlpine, S.R.⁴

23
- 34247580055
- K. Otrubova K. L. McGuire S. R. McAlpine J. Med. Chem. 2007 50 1999 2002
- (2007) J. Med. Chem. , vol.50 , pp. 1999-2002
- Otrubova, K.¹ McGuire, K.L.² McAlpine, S.R.³

24
- 34547855100
- P. S. Pan K. McGuire S. R. McAlpine Bioorg. Med. Chem. Lett. 2007 17 5072 5077
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 5072-5077
- Pan, P.S.¹ McGuire, K.² McAlpine, S.R.³

25
- 33947246678
- R. A. Rodriguez P.-S. Pan C.-M. Pan S. Ravula S. A. Lapera E. K. Singh T. J. Styers J. D. Brown J. Cajica E. Parry K. Otrubova S. R. McAlpine J. Org. Chem. 2007 72 1980 2002
- (2007) J. Org. Chem. , vol.72 , pp. 1980-2002
- Rodriguez, R.A.¹ Pan, P.-S.² Pan, C.-M.³ Ravula, S.⁴ Lapera, S.A.⁵ Singh, E.K.⁶ Styers, T.J.⁷ Brown, J.D.⁸ Cajica, J.⁹ Parry, E.¹⁰ Otrubova, K.¹¹ McAlpine, S.R.¹²

26
- 39149096281
- K. Otrubova G. H. Lushington D. Vander Velde K. L. McGuire S. R. McAlpine J. Med. Chem. 2008 51 530 544
- (2008) J. Med. Chem. , vol.51 , pp. 530-544
- Otrubova, K.¹ Lushington, G.H.² Vander Velde, D.³ McGuire, K.L.⁴ McAlpine, S.R.⁵

27
- 68149175130
- P. S. Pan R. C. Vasko S. A. Lapera V. A. Johnson R. P. Sellers C.-C. Lin C.-M. Pan M. R. Davis V. C. Ardi S. R. McAlpine Bioorg. Med. Chem. 2009 17 5806 5825
- (2009) Bioorg. Med. Chem. , vol.17 , pp. 5806-5825
- Pan, P.S.¹ Vasko, R.C.² Lapera, S.A.³ Johnson, V.A.⁴ Sellers, R.P.⁵ Lin, C.-C.⁶ Pan, C.-M.⁷ Davis, M.R.⁸ Ardi, V.C.⁹ McAlpine, S.R.¹⁰

28
- 77956339835
- R. P. Sellers L. D. Alexander V. A. Johnson C.-C. Lin J. Savage R. Corral J. Moss T. S. Slugocki E. K. Singh M. R. Davis S. Ravula J. E. Spicer J. L. Oelrich A. Thornquist C.-M. Pan S. R. McAlpine Bioorg. Med. Chem. 2010 18 6822 6856
- (2010) Bioorg. Med. Chem. , vol.18 , pp. 6822-6856
- Sellers, R.P.¹ Alexander, L.D.² Johnson, V.A.³ Lin, C.-C.⁴ Savage, J.⁵ Corral, R.⁶ Moss, J.⁷ Slugocki, T.S.⁸ Singh, E.K.⁹ Davis, M.R.¹⁰ Ravula, S.¹¹ Spicer, J.E.¹² Oelrich, J.L.¹³ Thornquist, A.¹⁴ Pan, C.-M.¹⁵ McAlpine, S.R.¹⁶

29
- 79960918066
- J. B. Kunicki M. N. Petersen L. D. Alexander V. C. Ardi J. R. McConnell S. R. McAlpine Bioorg. Med. Chem. Lett. 2011 21 4716 4719
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 4716-4719
- Kunicki, J.B.¹ Petersen, M.N.² Alexander, L.D.³ Ardi, V.C.⁴ McConnell, J.R.⁵ McAlpine, S.R.⁶

30
- 84855453441
- M. R. Davis E. K. Singh H. Wahyudi L. D. Alexander J. Kunicki L. A. Nazarova K. A. Fairweather A. M. Giltrap K. A. Jolliffe S. R. McAlpine Tetrahedron 2012 68 1029 1051
- (2012) Tetrahedron , vol.68 , pp. 1029-1051
- Davis, M.R.¹ Singh, E.K.² Wahyudi, H.³ Alexander, L.D.⁴ Kunicki, J.⁵ Nazarova, L.A.⁶ Fairweather, K.A.⁷ Giltrap, A.M.⁸ Jolliffe, K.A.⁹ McAlpine, S.R.¹⁰

31
- 80255131088
- L. D. Alexander J. R. Partridge D. A. Agard S. R. McAlpine Bioorg. Med. Chem. Lett. 2011 21 7068 7071
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 7068-7071
- Alexander, L.D.¹ Partridge, J.R.² Agard, D.A.³ McAlpine, S.R.⁴

32
- 84859848652
- D. M. Ramsey J. R. McConnell L. D. Alexander K. W. Tanaka C. M. Vera S. R. Mcalpine Bioorg. Med. Chem. Lett. 2012 22 3287 3290
- (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 3287-3290
- Ramsey, D.M.¹ McConnell, J.R.² Alexander, L.D.³ Tanaka, K.W.⁴ Vera, C.M.⁵ McAlpine, S.R.⁶

33
- 84857995559
- V. C. Ardi L. D. Alexander V. A. Johnson S. R. McAlpine ACS Chem. Biol. 2011 6 1357 1366
- (2011) ACS Chem. Biol. , vol.6 , pp. 1357-1366
- Ardi, V.C.¹ Alexander, L.D.² Johnson, V.A.³ McAlpine, S.R.⁴

34
- 80255131088
- L. D. Alexander J. R. Partridge D. A. Agard S. R. McAlpine Bioorg. Med. Chem. Lett. 2011 21 7068 7071
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 7068-7071
- Alexander, L.D.¹ Partridge, J.R.² Agard, D.A.³ McAlpine, S.R.⁴

35
- 0030759476
- S. T. Diver S. L. Schreiber J. Am. Chem. Soc. 1997 119 5106 5109
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 5106-5109
- Diver, S.T.¹ Schreiber, S.L.²

36
- 0031892994
- J. D. Klemm S. L. Schreiber G. R. Crabtree Annu. Rev. Immunol. 1998 16 569 592
- (1998) Annu. Rev. Immunol. , vol.16 , pp. 569-592
- Klemm, J.D.¹ Schreiber, S.L.² Crabtree, G.R.³

37
- 80052801777
- B. R. Kusuma L. B. Peterson H. Zhao G. Vielhauer J. Holzbeierlein B. S. Blagg J. Med. Chem. 2011 54 6234 6253
- (2011) J. Med. Chem. , vol.54 , pp. 6234-6253
- Kusuma, B.R.¹ Peterson, L.B.² Zhao, H.³ Vielhauer, G.⁴ Holzbeierlein, J.⁵ Blagg, B.S.⁶

38
- 4544228227
- M. L. Miller E. E. Roller R. Y. Zhao B. A. Leece O. Ab E. Baloglu V. S. Goldmacher R. V. J. Chari J. Med. Chem. 2004 47 4802 4805
- (2004) J. Med. Chem. , vol.47 , pp. 4802-4805
- Miller, M.L.¹ Roller, E.E.² Zhao, R.Y.³ Leece, B.A.⁴ Ab, O.⁵ Baloglu, E.⁶ Goldmacher, V.S.⁷ Chari, R.V.J.⁸

39
- 33646176246
- M. M. U. Ali S. M. Roe C. K. Vaughan P. Meyer B. Panaretou P. W. Piper C. Prodromou L. H. Pearl Nature 2006 440 1013 1017
- (2006) Nature , vol.440 , pp. 1013-1017
- Ali, M.M.U.¹ Roe, S.M.² Vaughan, C.K.³ Meyer, P.⁴ Panaretou, B.⁵ Piper, P.W.⁶ Prodromou, C.⁷ Pearl, L.H.⁸

40
- 79959344309
- D. R. Southworth D. A. Agard Mol. Cell 2011 42 771 781
- (2011) Mol. Cell , vol.42 , pp. 771-781
- Southworth, D.R.¹ Agard, D.A.²

41
- 49649117517
- S. K. Wandinger K. Richter J. Buchner J. Biol. Chem. 2008 283 18473 18477
- (2008) J. Biol. Chem. , vol.283 , pp. 18473-18477
- Wandinger, S.K.¹ Richter, K.² Buchner, J.³

42
- 79957488833
- C.-C. Lee T.-W. Lin T.-P. Ko A. H.-J. Wang PLoS One 2011 6 e19961
- (2011) PLoS One , vol.6 , pp. 19961
- Lee, C.-C.¹ Lin, T.-W.² Ko, T.-P.³ Wang, A.H.-J.⁴

43
- 79959299594
- Z. L. Hildenbrand S. K. Molugu N. Herrera C. Ramirez C. Xiao R. A. Bernal Oncotarget 2011 2 43 58
- (2011) Oncotarget , vol.2 , pp. 43-58
- Hildenbrand, Z.L.¹ Molugu, S.K.² Herrera, N.³ Ramirez, C.⁴ Xiao, C.⁵ Bernal, R.A.⁶

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