The platelet-derived growth factor receptor α is destabilized by geldanamycins in cancer cells

Journal of Biological Chemistry

Volumn 282, Issue 1, 2007, Pages 445-453

  Matei, Daniela ^a,b   Satpathy, Minati ^a   Cao, Liyun ^a   Lai, Yi Chun ^a   Nakshatri, Harikrishna ^a,b   Donner, David B ^c  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLIOBLASTOMA; GROWTH FACTOR; MALIGNANCIES;

ANTIBIOTICS; HORMONES; MUSCLE; PLATELETS; TUMORS;

PROTEINS;

17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CELL CYCLE PROTEIN 37; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; IMATINIB; NEUTRALIZING ANTIBODY; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEASOME INHIBITOR; PROTEIN TYROSINE KINASE; 17-(ALLYLAMINO)-17-DEMETHOXYGELDANAMYCIN; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIBIOTIC; BENZOQUINONE DERIVATIVE; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; LEUPEPTIN; MACROCYCLIC LACTAM; PIPERAZINE DERIVATIVE; PLATELET DERIVED GROWTH FACTOR; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL PROLIFERATION; CELL STRAIN 3T3; CELL STRAIN COS1; FEMALE; FIBROBLAST; GLIOBLASTOMA; HUMAN; HUMAN CELL; LUNG CANCER; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROTEIN DEGRADATION; SMOOTH MUSCLE FIBER; ANIMAL; CHEMISTRY; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

3T3 CELLS; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; BENZOQUINONES; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; LACTAMS, MACROCYCLIC; LEUPEPTINS; MICE; PIPERAZINES; PLATELET-DERIVED GROWTH FACTOR; PYRIMIDINES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; SIGNAL TRANSDUCTION;

EID: 33846982944     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M607012200     Document Type: Article

References (52)

1. Basso, A. D., Solit, D. B., Munster, P. N., and Rosen, N. (2002) Oncogene 21, 1159-1166
2. Xu, W., Mimnaugh, E., Rosser, M. F., Nicchitta, C., Marcu, M., Yarden, Y., and Neckers, L. (2001) J. Biol. Chem. 276, 3702-3708
3. Xu, W., Mimnaugh, E. G., Kim, J. S., Trepel, J. B., and Neckers, L. M. (2002) Cell Stress Chaperones 7, 91-96
4. Xu, W., Yuan, X., Xiang, Z., Mimnaugh, E., Marcu, M., and Neckers, L. (2005) Nat. Struct. Mol. Biol. 12, 120-126
5. Shimamura, T., Lowell, A. M., Engelman, J. A., and Shapiro, G. I. (2005) Cancer Res. 65, 6401-6408
6. Bohen, S. P., and Yamamoto, K. R. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 11424-11428
7. Nathan, D. F., and Lindquist, S. (1995) Mol. Cell. Biol. 15, 3917-3925
8. Picard, D., Khursheed, B., Garabedian, M. J., Fortin, M. G., Lindquist, S., and Yamamoto, K. R. (1990) Nature 348, 166-168
9. Basso, A. D., Solit, D. B., Chiosis, G., Giri, B., Tsichlis, P., and Rosen, N. (2002) J. Biol. Chem. 277, 39858-39866
10. da Rocha Dias, S., Friedlos, F., Light, Y., Springer, C., Workman, P., and Marais, R. (2005) Cancer Res. 65, 10686-10691
11. Grammatikakis, N., Lin, J. H., Grammatikakis, A., Tsichlis, P. N., and Cochran, B. H. (1999) Mol. Cell. Biol. 19, 1661-1672
12. Xu, Y., Singer, M. A., and Lindquist, S. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 109-114
13. Blagosklonny, M. V., Toretsky, J., Bohen, S., and Neckers, L. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8379-8383
14. Blagosklonny, M. V., Fojo, T., Bhalla, K. N., Kim, J. S., Trepel, J. B., Figg, W. D., Rivera, Y., and Neckers, L. M. (2001) Leukemia 15, 1537-1543
15. Nimmanapalli, R., O'Bryan, E., and Bhalla, K. (2001) Cancer Res. 61, 1799-1804
16. Wiech, H., Buchner, J., Zimmermann, R., and Jakob, U. (1992) Nature 358, 169-170
17. Whitesell, L., and Lindquist, S. L. (2005) Nat. Rev. Cancer 5, 761-772
18. Kamal, A., Thao, L., Sensintaffar, J., Zhang, L., Boehm, M. F., Fritz, L. C., and Burrows, F. J. (2003) Nature 425, 407-410
19. Prodromou, C., Roe, S. M., O'Brien, R., Ladbury, J. E., Piper, P. W., and Pearl, L. H. (1997) Cell 90, 65-75
20. Stebbins, C. E., Russo, A. A., Schneider, C., Rosen, N., Hartl, F. U., and Pavletich, N. P. (1997) Cell 89, 239-250
21. Bagatell, R., and Whitesell, L. (2004) Mol. Cancer Ther. 3, 1021-1030
22. Mao, X., and Hamoudi, R. A. (2000) Cancer Genet. Cytogenet. 122, 87-92
23. Heinrich, M. C., Corless, C. L., Duensing, A., McGreevey, L., Chen, C. J., Joseph, N., Singer, S., Griffith, D. J., Haley, A., Town, A., Demetri, G. D., Fletcher, C. D., and Fletcher, J. A. (2003) Science 299, 708-710
24. MacDonald, T. J., Brown, K. M., LaFleur, B., Peterson, K., Lawlor, C., Chen, Y., Packer, R. J., Cogen, P., and Stephan, D. A. (2001) Nat. Genet. 29, 143-152
25. Oda, Y., Wehrmann, B., Radig, K., Walter, H., Rose, I., Neumann, W., and Roessner, A. (1995) Gen. Diagn. Pathol. 141, 97-103
26. Henriksen, R., Funa, K., Wilander, E., Backstrom, T., Ridderheim, M., and Oberg, K. (1993) Cancer Res. 53, 4550-4554
27. Schmandt, R. E., Broaddus, R., Lu, K. H., Shvartsman, H., Thornton, A., Malpica, A., Sun, C., Bodurka, D. C., and Gershenson, D. M. (2003) Cancer 98, 758-764
28. Matei, D., Chang, D. D., and Jeng, M. H. (2004) Clin. Cancer Res. 10, 681-690
29. Kawai, T., Hiroi, S., and Torikata, C. (1997) Lab. Invest. 77, 431-436
30. Matei, D., Emerson, R. E., Lai, Y. C., Baldridge, L. A., Rao, J., Yiannoutsos, C., and Donner, D. D. (2006) Oncogene 25, 2060-2069
31. Matsui, T., Heidaran, M., Miki, T., Popescu, N., La Rochelle, W., Kraus, M., Pierce, J., and Aaronson, S. (1989) Science 243, 800-804
32. Yao, R., and Cooper, G. M. (1995) Science 267, 2003-2006
33. Huang, J. S., Huang, S. S., and Deuel, T. F. (1984) Cell 39, 79-87
34. Yu, J., Moon, A., and Kim, H. R. (2001) Biochem. Biophys. Res. Commun. 282, 697-700
35. Greenhalgh, D. G., Sprugel, K. H., Murray, M. J., and Ross, R. (1990) Am. J. Pathol. 136, 1235-1246
36. Loizos, N., Xu, Y., Huber, J., Liu, M., Lu, D., Finnerty, B., Rolser, R., Malikzay, A., Persaud, A., Corcoran, E., Deevi, D. S., Balderes, P., Bassi, R., Jimenez, X., Joynes, C. J., Mangalampalli, V. R., Steiner, P., Tonra, J. R., Wu, Y., Pereira, D. S., Zhu, Z., Ludwig, D. L., Hicklin, D. J., Bohlen, P., Witte, L., and Kussie, P. (2005) Mol. Cancer Ther. 4, 369-379
37. Gillan, L., Matei, D., Fishman, D. A., Gerbin, C. S., Karlan, B. Y., and Chang, D. D. (2002) Cancer Res. 62, 5358-5364
38. Beppu, K., Jaboine, J., Merchant, M. S., Mackall, C. L., and Thiele, C. J. (2004) J. Natl. Cancer Inst. 96, 46-55
39. Huff, S. Y., Quilliam, L. A., Cox, A. D., and Der, C. J. (1997) Oncogene 14, 133-143
40. Arlander, S. J., Eapen, A. K., Vroman, B. T., McDonald, R. J., Toft, D. O., and Karnitz, L. M. (2003) J. Biol. Chem. 278, 52572-52577
41. Shang, L., and Tomasi, T. B. (2006) J. Biol. Chem. 281, 1876-1884
42. Matei, D., Graeber, T. G., Baldwin, R. L., Karlan, B. Y., Rao, J., and Chang, D. D. (2002) Oncogene 21, 6289-6298
43. Franke, T. F., Yang, S. I., Chan, T. O., Datta, K., Kazlauskas, A., Morrison, D. K., Kaplan, D. R., and Tsichlis, P. N. (1995) Cell 81, 727-736
44. Mori, S., Heldin, C. H., and Claesson-Welsh, L. (1992) J. Biol. Chem. 267, 6429-6434
45. Roe, S. M., Ali, M. M., Meyer, P., Vaughan, C. K., Panaretou, B., Piper, P. W., Prodromou, C., and Pearl, L. H. (2004) Cell 116, 87-98
46. Lavictoire, S. J., Parolin, D. A., Klimowicz, A. C., Kelly, J. F., and Lorimer, I. A. (2003) J. Biol. Chem. 278, 5292-5299
47. Hermanson, M., Funa, K., Hartman, M., Claesson-Welsh, L., Heldin, C. H., Westermark, B., and Nister, M. (1992) Cancer Res. 52, 3213-3219
48. Goetz, M. P., Toft, D., Reid, J., Ames, M., Stensgard, B., Safgren, S., Adjei, A. A., Sloan, J., Atherton, P., Vasile, V., Salazaar, S., Adjei, A., Croghan, G., and Erlichman, C. (2005) J. Clin. Oncol. 23, 1078-1087
49. Sakagami, M., Morrison, P., and Welch, W. J. (1999) Cell Stress Chaperones 4, 19-28
50. Westermark, B., Heldin, C. H., and Nister, M. (1995) Glia 15, 257-263
51. Xu, W., Yuan, X., Jung, Y. J., Yang, Y., Basso, A., Rosen, N., Chung, E. J., Trepel, J., and Neckers, L. (2003) Cancer Res. 63, 7777-7784
52. Haglund, K., Di Fiore, P. P., and Dikic, I. (2003) Trends Biochem. Sci. 28, 598-603