-
1
-
-
77957240422
-
Lu AE58054, a 5-HT(6) antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats
-
1:CAS:528:DC%2BC3cXhtVCksLnK 20569520 10.1017/S1461145710000659
-
Arnt J, Bang-Andersen B, Grayson B, Bymaster FP, Cohen MP, DeLapp NW, Giethlen B, Kreilgaard M, Mckinzie DL, Neill JC, Nelson DL, Nielsen SM, Poulsen MN, Schaus JM, Witten LM (2010) Lu AE58054, a 5-HT(6) antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats. Int J Neuropsychopharmacol 13:1021-1033
-
(2010)
Int J Neuropsychopharmacol
, vol.13
, pp. 1021-1033
-
-
Arnt, J.1
Bang-Andersen, B.2
Grayson, B.3
Bymaster, F.P.4
Cohen, M.P.5
Delapp, N.W.6
Giethlen, B.7
Kreilgaard, M.8
McKinzie, D.L.9
Neill, J.C.10
Nelson, D.L.11
Nielsen, S.M.12
Poulsen, M.N.13
Schaus, J.M.14
Witten, L.M.15
-
2
-
-
0032030496
-
M100907, a selective 5-HT2A receptor antagonist and a potential antipsychotic drug, facilitates N-methyl-D-aspartate-receptor mediated neurotransmission in the rat medial prefrontal cortical neurons in vitro
-
1:CAS:528:DyaK1cXptlGgsA%3D%3D 9471117 10.1016/S0893-133X(97)00126-7
-
Arvanov VL, Wang RY (1998) M100907, a selective 5-HT2A receptor antagonist and a potential antipsychotic drug, facilitates N-methyl-D-aspartate- receptor mediated neurotransmission in the rat medial prefrontal cortical neurons in vitro. Neuropsychopharmacology 18:197-209
-
(1998)
Neuropsychopharmacology
, vol.18
, pp. 197-209
-
-
Arvanov, V.L.1
Wang, R.Y.2
-
3
-
-
33747361259
-
Actions of novel antipsychotic agents on apomorphine-induced PPI disruption: Influence of combined serotonin 5-HT1A receptor activation and dopamine D2 receptor blockade
-
1:CAS:528:DC%2BD28XotFKlurY%3D 16421514 10.1038/sj.npp.1301015
-
Auclair AL, Kleven MS, Besnard J, Depoortere R, Newman-Tancredi A (2006) Actions of novel antipsychotic agents on apomorphine-induced PPI disruption: influence of combined serotonin 5-HT1A receptor activation and dopamine D2 receptor blockade. Neuropsychopharmacology 31:1900-1909
-
(2006)
Neuropsychopharmacology
, vol.31
, pp. 1900-1909
-
-
Auclair, A.L.1
Kleven, M.S.2
Besnard, J.3
Depoortere, R.4
Newman-Tancredi, A.5
-
4
-
-
0028143103
-
Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response
-
1:CAS:528:DyaK2MXisVOqu7o%3D 7965797
-
Bakshi VP, Swerdlow NR, Geyer MA (1994) Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response. J Pharmacol Exp Ther 271:787-794
-
(1994)
J Pharmacol Exp Ther
, vol.271
, pp. 787-794
-
-
Bakshi, V.P.1
Swerdlow, N.R.2
Geyer, M.A.3
-
5
-
-
0034493029
-
Effects of MK801 and neuroleptics on prepulse inhibition: Re-examination in two strains of rats
-
1:CAS:528:DC%2BD3MXnslSmsA%3D%3D 11164097 10.1016/S0091-3057(00)00409-3
-
Bast T, Zhang W, Feldon J, White IM (2000) Effects of MK801 and neuroleptics on prepulse inhibition: re-examination in two strains of rats. Pharmacol Biochem Behav 67:647-658
-
(2000)
Pharmacol Biochem Behav
, vol.67
, pp. 647-658
-
-
Bast, T.1
Zhang, W.2
Feldon, J.3
White, I.M.4
-
6
-
-
0030995586
-
Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells
-
1:CAS:528:DyaK2sXktlSru7w%3D 9225298 10.1016/S0028-3908(97)00019-1
-
Boess FG, Monsma FJ Jr, Carolo C, Meyer V, Rudler A, Zwingelstein C, Sleight AJ (1997) Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells. Neuropharmacology 36:713-720
-
(1997)
Neuropharmacology
, vol.36
, pp. 713-720
-
-
Boess, F.G.1
Monsma, Jr.F.J.2
Carolo, C.3
Meyer, V.4
Rudler, A.5
Zwingelstein, C.6
Sleight, A.J.7
-
8
-
-
0025190458
-
Sensorimotor gating and schizophrenia. Human and animal model studies
-
1:STN:280:DyaK3c7ks1yksQ%3D%3D 2405807 10.1001/archpsyc.1990. 01810140081011
-
Braff DL, Geyer MA (1990) Sensorimotor gating and schizophrenia. Human and animal model studies. Arch Gen Psychiatry 47:181-188
-
(1990)
Arch Gen Psychiatry
, vol.47
, pp. 181-188
-
-
Braff, D.L.1
Geyer, M.A.2
-
9
-
-
22444441301
-
The effect of zotepine, risperidone, clozapine and olanzapine on MK-801-disrupted sensorimotor gating
-
1:CAS:528:DC%2BD2MXivFKmtrY%3D 15820528 10.1016/j.pbb.2005.01.012
-
Bubenikova V, Votava M, Horacek J, Palenicek T, Dockery C (2005) The effect of zotepine, risperidone, clozapine and olanzapine on MK-801-disrupted sensorimotor gating. Pharmacol Biochem Behav 80:591-596
-
(2005)
Pharmacol Biochem Behav
, vol.80
, pp. 591-596
-
-
Bubenikova, V.1
Votava, M.2
Horacek, J.3
Palenicek, T.4
Dockery, C.5
-
10
-
-
78649282727
-
Emerging role of sertindole in the management of schizophrenia
-
1:CAS:528:DC%2BC3cXptlGrsb4%3D 2938292 20856607
-
Cincotta SL, Rodefer JS (2010) Emerging role of sertindole in the management of schizophrenia. Neuropsychiatr Dis Treat 6:429-441
-
(2010)
Neuropsychiatr Dis Treat
, vol.6
, pp. 429-441
-
-
Cincotta, S.L.1
Rodefer, J.S.2
-
11
-
-
0027298969
-
Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats
-
1:CAS:528:DyaK3sXktVSku7Y%3D 8100055 10.1016/0304-3940(93)90483-2
-
Daly DA, Moghaddam B (1993) Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats. Neurosci Lett 152:61-64
-
(1993)
Neurosci Lett
, vol.152
, pp. 61-64
-
-
Daly, D.A.1
Moghaddam, B.2
-
12
-
-
0034782825
-
The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus
-
1:CAS:528:DC%2BD3MXnslCjsbw%3D 11682249 10.1016/S0893-133X(01)00265-2
-
Dawson LA, Nguyen HQ, Li P (2001) The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus. Neuropsychopharmacology 25:662-668
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 662-668
-
-
Dawson, L.A.1
Nguyen, H.Q.2
Li, P.3
-
13
-
-
0037441579
-
Potentiation of amphetamine-induced changes in dopamine and 5-HT by a 5-HT(6) receptor antagonist
-
1:CAS:528:DC%2BD3sXptFGisw%3D%3D 12576149 10.1016/S0361-9230(02)00967-X
-
Dawson LA, Nguyen HQ, Li P (2003) Potentiation of amphetamine-induced changes in dopamine and 5-HT by a 5-HT(6) receptor antagonist. Brain Res Bull 59:513-521
-
(2003)
Brain Res Bull
, vol.59
, pp. 513-521
-
-
Dawson, L.A.1
Nguyen, H.Q.2
Li, P.3
-
14
-
-
0033609543
-
Effects of clozapine and haloperidol on 5-HT6 receptor mRNA levels in rat brain
-
1:STN:280:DyaK1Mzls1KisQ%3D%3D 10427606 10.1016/S0920-9964(99)00002-X
-
Frederick JA, Meador-Woodruff JH (1999) Effects of clozapine and haloperidol on 5-HT6 receptor mRNA levels in rat brain. Schizophr Res 38:7-12
-
(1999)
Schizophr Res
, vol.38
, pp. 7-12
-
-
Frederick, J.A.1
Meador-Woodruff, J.H.2
-
15
-
-
0030614562
-
Immuno-localization of serotonin 5-HT6 receptor-like material in the rat central nervous system
-
1:CAS:528:DyaK2sXktlOltA%3D%3D 9037500 10.1016/S0006-8993(96)01224-3
-
Gerard C, Martres MP, Lefevre K, Miquel MC, Verge D, Lanfumey L, Doucet E, Hamon M, El Mestikawy S (1997) Immuno-localization of serotonin 5-HT6 receptor-like material in the rat central nervous system. Brain Res 746:207-219
-
(1997)
Brain Res
, vol.746
, pp. 207-219
-
-
Gerard, C.1
Martres, M.P.2
Lefevre, K.3
Miquel, M.C.4
Verge, D.5
Lanfumey, L.6
Doucet, E.7
Hamon, M.8
El Mestikawy, S.9
-
16
-
-
0034917841
-
Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: A decade in review
-
1:CAS:528:DC%2BD3MXmtlCqtLY%3D 10.1007/s002130100811
-
Geyer MA, Krebs-Thomson K, Braff DL, Swerdlow NR (2001) Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl) 156:117-154
-
(2001)
Psychopharmacology (Berl)
, vol.156
, pp. 117-154
-
-
Geyer, M.A.1
Krebs-Thomson, K.2
Braff, D.L.3
Swerdlow, N.R.4
-
17
-
-
0029295914
-
Clozapine: Selective labeling of sites resembling 5HT6 serotonin receptors may reflect psychoactive profile
-
1:CAS:528:DyaK2MXmsVGgtbc%3D 2229994 8521297
-
Glatt CE, Snowman AM, Sibley DR, Snyder SH (1995) Clozapine: selective labeling of sites resembling 5HT6 serotonin receptors may reflect psychoactive profile. Mol Med 1:398-406
-
(1995)
Mol Med
, vol.1
, pp. 398-406
-
-
Glatt, C.E.1
Snowman, A.M.2
Sibley, D.R.3
Snyder, S.H.4
-
18
-
-
79952992514
-
Effects of 5-HT6 antagonists, Ro-4368554 and SB-258585, in tests used for the detection of cognitive enhancement and antipsychotic-like activity
-
1:CAS:528:DC%2BC3MXivVCqs7s%3D 21301322 10.1097/FBP.0b013e328343d804
-
Gravius A, Laszy J, Pietraszek M, Saghy K, Nagel J, Chambon C, Wegener N, Valastro B, Danysz W, Gyertyan I (2011) Effects of 5-HT6 antagonists, Ro-4368554 and SB-258585, in tests used for the detection of cognitive enhancement and antipsychotic-like activity. Behav Pharmacol 22:122-135
-
(2011)
Behav Pharmacol
, vol.22
, pp. 122-135
-
-
Gravius, A.1
Laszy, J.2
Pietraszek, M.3
Saghy, K.4
Nagel, J.5
Chambon, C.6
Wegener, N.7
Valastro, B.8
Danysz, W.9
Gyertyan, I.10
-
19
-
-
79955964765
-
Effect of cannabidiol in a MK-801-rodent model of aspects of schizophrenia
-
1:CAS:528:DC%2BC3MXmtFWqt7c%3D 21458498 10.1016/j.bbr.2011.03.053
-
Gururajan A, Taylor DA, Malone DT (2011) Effect of cannabidiol in a MK-801-rodent model of aspects of schizophrenia. Behav Brain Res 222:299-308
-
(2011)
Behav Brain Res
, vol.222
, pp. 299-308
-
-
Gururajan, A.1
Taylor, D.A.2
Malone, D.T.3
-
21
-
-
0031783008
-
Localizing haloperidol effects on sensorimotor gating in a predictive model of antipsychotic potency
-
1:CAS:528:DyaK1cXlsVaht78%3D 9715813 10.1016/S0091-3057(98)00079-3
-
Hart S, Zreik M, Carper R, Swerdlow NR (1998) Localizing haloperidol effects on sensorimotor gating in a predictive model of antipsychotic potency. Pharmacol Biochem Behav 61:113-119
-
(1998)
Pharmacol Biochem Behav
, vol.61
, pp. 113-119
-
-
Hart, S.1
Zreik, M.2
Carper, R.3
Swerdlow, N.R.4
-
22
-
-
26444461639
-
5-HT6 receptor antagonists improve performance in an attentional set shifting task in rats
-
1:CAS:528:DC%2BD2MXhtFCrtL3L 10.1007/s00213-005-2261-z
-
Hatcher PD, Brown VJ, Tait DS, Bate S, Overend P, Hagan JJ, Jones DN (2005) 5-HT6 receptor antagonists improve performance in an attentional set shifting task in rats. Psychopharmacology (Berl) 181:253-259
-
(2005)
Psychopharmacology (Berl)
, vol.181
, pp. 253-259
-
-
Hatcher, P.D.1
Brown, V.J.2
Tait, D.S.3
Bate, S.4
Overend, P.5
Hagan, J.J.6
Jones, D.N.7
-
23
-
-
33751162382
-
SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models
-
1:CAS:528:DC%2BD28Xht1Ciu7nO 17069795 10.1016/j.ejphar.2006.09.049
-
Hirst WD, Stean TO, Rogers DC, Sunter D, Pugh P, Moss SF, Bromidge SM, Riley G, Smith DR, Bartlett S, Heidbreder CA, Atkins AR, Lacroix LP, Dawson LA, Foley AG, Regan CM, Upton N (2006) SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models. Eur J Pharmacol 553:109-119
-
(2006)
Eur J Pharmacol
, vol.553
, pp. 109-119
-
-
Hirst, W.D.1
Stean, T.O.2
Rogers, D.C.3
Sunter, D.4
Pugh, P.5
Moss, S.F.6
Bromidge, S.M.7
Riley, G.8
Smith, D.R.9
Bartlett, S.10
Heidbreder, C.A.11
Atkins, A.R.12
Lacroix, L.P.13
Dawson, L.A.14
Foley, A.G.15
Regan, C.M.16
Upton, N.17
-
24
-
-
0027286113
-
The effects of haloperidol and clozapine on the disruption of sensorimotor gating induced by the noncompetitive glutamate antagonist MK-801
-
1:CAS:528:DyaK3sXlsFWqur8%3D 10.1007/BF02244950
-
Hoffman DC, Donovan H, Cassella JV (1993) The effects of haloperidol and clozapine on the disruption of sensorimotor gating induced by the noncompetitive glutamate antagonist MK-801. Psychopharmacology (Berl) 111:339-344
-
(1993)
Psychopharmacology (Berl)
, vol.111
, pp. 339-344
-
-
Hoffman, D.C.1
Donovan, H.2
Cassella, J.V.3
-
25
-
-
0026040158
-
Failure of haloperidol to block the effects of phencyclidine and dizocilpine on prepulse inhibition of startle
-
1:CAS:528:DyaK3MXmsVOqtrg%3D 1834231 10.1016/0006-3223(91)90025-H
-
Keith VA, Mansbach RS, Geyer MA (1991) Failure of haloperidol to block the effects of phencyclidine and dizocilpine on prepulse inhibition of startle. Biol Psychiatry 30:557-566
-
(1991)
Biol Psychiatry
, vol.30
, pp. 557-566
-
-
Keith, V.A.1
Mansbach, R.S.2
Geyer, M.A.3
-
26
-
-
79251605205
-
Prefrontal NMDA receptor antagonism reduces impairments in pre-attentive information processing
-
1:CAS:528:DC%2BC3MXhtlejtr4%3D 21111580 10.1016/j.euroneuro.2010.10.010
-
Klamer D, Svensson L, Fejgin K, Palsson E (2011) Prefrontal NMDA receptor antagonism reduces impairments in pre-attentive information processing. Eur Neuropsychopharmacol 21:248-253
-
(2011)
Eur Neuropsychopharmacol
, vol.21
, pp. 248-253
-
-
Klamer, D.1
Svensson, L.2
Fejgin, K.3
Palsson, E.4
-
27
-
-
0038107717
-
Effect of the 5-HT6 receptor antagonists Ro04-6790 and Ro65-7199 on latent inhibition and prepulse inhibition in the rat: Comparison to clozapine
-
1:CAS:528:DC%2BD3sXlsVansbo%3D 12873617 10.1016/S0091-3057(03)00082-0
-
Leng A, Ouagazzal A, Feldon J, Higgins GA (2003) Effect of the 5-HT6 receptor antagonists Ro04-6790 and Ro65-7199 on latent inhibition and prepulse inhibition in the rat: comparison to clozapine. Pharmacol Biochem Behav 75:281-288
-
(2003)
Pharmacol Biochem Behav
, vol.75
, pp. 281-288
-
-
Leng, A.1
Ouagazzal, A.2
Feldon, J.3
Higgins, G.A.4
-
28
-
-
18044383794
-
Nicotine and clozapine actions on pre-pulse inhibition deficits caused by N-methyl-D-aspartate (NMDA) glutamatergic receptor blockade
-
1:CAS:528:DC%2BD2MXjs1Giurc%3D 15866361 10.1016/j.pnpbp.2005.01.012
-
Levin ED, Petro A, Caldwell DP (2005) Nicotine and clozapine actions on pre-pulse inhibition deficits caused by N-methyl-D-aspartate (NMDA) glutamatergic receptor blockade. Prog Neuropsychopharmacol Biol Psychiatry 29:581-586
-
(2005)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.29
, pp. 581-586
-
-
Levin, E.D.1
Petro, A.2
Caldwell, D.P.3
-
29
-
-
33846348402
-
5-HT(6) receptor antagonist SB-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus
-
1:CAS:528:DC%2BD2sXpvFSjsg%3D%3D 17207474 10.1016/j.brainres.2006.11.060
-
Li Z, Huang M, Prus AJ, Dai J, Meltzer HY (2007) 5-HT(6) receptor antagonist SB-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus. Brain Res 1134:70-78
-
(2007)
Brain Res
, vol.1134
, pp. 70-78
-
-
Li, Z.1
Huang, M.2
Prus, A.J.3
Dai, J.4
Meltzer, H.Y.5
-
30
-
-
33645029075
-
Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice
-
1:CAS:528:DC%2BD28XitlKms7c%3D 16052245 10.1038/sj.npp.1300838
-
Long LE, Malone DT, Taylor DA (2006) Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice. Neuropsychopharmacology 31:795-803
-
(2006)
Neuropsychopharmacology
, vol.31
, pp. 795-803
-
-
Long, L.E.1
Malone, D.T.2
Taylor, D.A.3
-
31
-
-
84891836759
-
-
Study ID: 12450A. ClinicalTrials.gov Identifier: 00810667. Title: Efficacy study exploring the effect of Lu AE58054 as augmentation therapy in patients with Schizophrenia
-
Lundbeck (2008) Study ID: 12450A. ClinicalTrials.gov Identifier: 00810667. Title: Efficacy study exploring the effect of Lu AE58054 as augmentation therapy in patients with Schizophrenia
-
(2008)
Lundbeck
-
-
-
32
-
-
50349086807
-
Antipsychotic property of a muscarinic receptor agonist in animal models for schizophrenia
-
1:CAS:528:DC%2BD1cXhtVylu7%2FN 18651995 10.1016/j.pbb.2008.06.023
-
Maehara S, Hikichi H, Satow A, Okuda S, Ohta H (2008) Antipsychotic property of a muscarinic receptor agonist in animal models for schizophrenia. Pharmacol Biochem Behav 91:140-149
-
(2008)
Pharmacol Biochem Behav
, vol.91
, pp. 140-149
-
-
Maehara, S.1
Hikichi, H.2
Satow, A.3
Okuda, S.4
Ohta, H.5
-
33
-
-
80052024632
-
Antipsychotic effects of N-desmethylclozapine on sensorimotor gating function in rats-possible involvement of activation of M(1) muscarinic receptors
-
1:CAS:528:DC%2BC3MXhtVGlt7zM 21658379 10.1016/j.ejphar.2011.05.063
-
Maehara S, Satow A, Hikichi H, Ohta H (2011) Antipsychotic effects of N-desmethylclozapine on sensorimotor gating function in rats-possible involvement of activation of M(1) muscarinic receptors. Eur J Pharmacol 667:242-249
-
(2011)
Eur J Pharmacol
, vol.667
, pp. 242-249
-
-
Maehara, S.1
Satow, A.2
Hikichi, H.3
Ohta, H.4
-
34
-
-
84879206282
-
The atypical antipsychotic risperidone reverses the recognition memory deficits induced by post-weaning social isolation in rats
-
McIntosh AL, Ballard TM, Steward LJ, Moran PM, Fone KC (2013) The atypical antipsychotic risperidone reverses the recognition memory deficits induced by post-weaning social isolation in rats. Psychopharmacology (Berl) 228: 31-42
-
(2013)
Psychopharmacology (Berl)
, vol.228
, pp. 31-42
-
-
McIntosh, A.L.1
Ballard, T.M.2
Steward, L.J.3
Moran, P.M.4
Fone, K.C.5
-
36
-
-
79951531704
-
5-HT6 receptor memory and amnesia: Behavioral pharmacology - Learning and memory processes
-
1:CAS:528:DC%2BC3MXpsFGks74%3D 21329783
-
Meneses A, Perez-Garcia G, Ponce-Lopez T, Castillo C (2011) 5-HT6 receptor memory and amnesia: behavioral pharmacology - learning and memory processes. Int Rev Neurobiol 96:27-47
-
(2011)
Int Rev Neurobiol
, vol.96
, pp. 27-47
-
-
Meneses, A.1
Perez-Garcia, G.2
Ponce-Lopez, T.3
Castillo, C.4
-
37
-
-
28044437798
-
5-HT6 receptors: A novel target for cognitive enhancement
-
1:CAS:528:DC%2BD2MXht1Olsr%2FO 16005519 10.1016/j.pharmthera.2005.05.001
-
Mitchell ES, Neumaier JF (2005) 5-HT6 receptors: a novel target for cognitive enhancement. Pharmacol Ther 108:320-333
-
(2005)
Pharmacol Ther
, vol.108
, pp. 320-333
-
-
Mitchell, E.S.1
Neumaier, J.F.2
-
38
-
-
36148938722
-
5-HT6 receptor antagonist reversal of emotional learning and prepulse inhibition deficits induced by apomorphine or scopolamine
-
1:CAS:528:DC%2BD2sXhtlCru7rL 2322863 17920665 10.1016/j.pbb.2007.08.015
-
Mitchell ES, Neumaier JF (2008) 5-HT6 receptor antagonist reversal of emotional learning and prepulse inhibition deficits induced by apomorphine or scopolamine. Pharmacol Biochem Behav 88:291-298
-
(2008)
Pharmacol Biochem Behav
, vol.88
, pp. 291-298
-
-
Mitchell, E.S.1
Neumaier, J.F.2
-
39
-
-
69049088714
-
Effect of sertindole on extracellular dopamine, acetylcholine, and glutamate in the medial prefrontal cortex of conscious rats: A comparison with risperidone and exploration of mechanisms involved
-
10.1007/s00213-009-1578-4
-
Mork A, Witten LM, Arnt J (2009) Effect of sertindole on extracellular dopamine, acetylcholine, and glutamate in the medial prefrontal cortex of conscious rats: a comparison with risperidone and exploration of mechanisms involved. Psychopharmacology (Berl) 206:39-49
-
(2009)
Psychopharmacology (Berl)
, vol.206
, pp. 39-49
-
-
Mork, A.1
Witten, L.M.2
Arnt, J.3
-
40
-
-
84864881933
-
Double-blind placebo-controlled randomized efficacy and safety trial of add-on treatment of dimebon plus risperidone in schizophrenic patients during transition from acute psychotic episode to remission
-
22706414
-
Morozova MA, Beniashvili AG, Lepilkina TA, Rupchev GE (2012) Double-blind placebo-controlled randomized efficacy and safety trial of add-on treatment of dimebon plus risperidone in schizophrenic patients during transition from acute psychotic episode to remission. Psychiatr Danub 24:159-166
-
(2012)
Psychiatr Danub
, vol.24
, pp. 159-166
-
-
Morozova, M.A.1
Beniashvili, A.G.2
Lepilkina, T.A.3
Rupchev, G.E.4
-
41
-
-
79961166634
-
Comparative pharmacology of antipsychotics possessing combined dopamine D(2) and serotonin 5-HT (1A) receptor properties
-
1:CAS:528:DC%2BC3MXivFyqtr0%3D 10.1007/s00213-011-2247-y
-
Newman-Tancredi A, Kleven MS (2011) Comparative pharmacology of antipsychotics possessing combined dopamine D(2) and serotonin 5-HT (1A) receptor properties. Psychopharmacology (Berl) 216:451-473
-
(2011)
Psychopharmacology (Berl)
, vol.216
, pp. 451-473
-
-
Newman-Tancredi, A.1
Kleven, M.S.2
-
42
-
-
0036119234
-
Effects of the 5-HT(6) receptor antagonist, SB-271046, in animal models for schizophrenia
-
1:CAS:528:DC%2BD38XhvVChur4%3D 11888555 10.1016/S0091-3057(01)00743-2
-
Pouzet B, Didriksen M, Arnt J (2002) Effects of the 5-HT(6) receptor antagonist, SB-271046, in animal models for schizophrenia. Pharmacol Biochem Behav 71:635-643
-
(2002)
Pharmacol Biochem Behav
, vol.71
, pp. 635-643
-
-
Pouzet, B.1
Didriksen, M.2
Arnt, J.3
-
43
-
-
0037468873
-
Influence of the 5-HT6 receptor on acetylcholine release in the cortex: Pharmacological characterization of 4-(2-bromo-6-pyrrolidin-1-ylpyridine-4- sulfonyl)phenylamine, a potent and selective 5-HT6 receptor antagonist
-
1:CAS:528:DC%2BD3sXhsVygu7s%3D 12646038 10.1021/jm021085c
-
Riemer C, Borroni E, Levet-Trafit B, Martin JR, Poli S, Porter RH, Bos M (2003) Influence of the 5-HT6 receptor on acetylcholine release in the cortex: pharmacological characterization of 4-(2-bromo-6-pyrrolidin-1-ylpyridine-4- sulfonyl)phenylamine, a potent and selective 5-HT6 receptor antagonist. J Med Chem 46:1273-1276
-
(2003)
J Med Chem
, vol.46
, pp. 1273-1276
-
-
Riemer, C.1
Borroni, E.2
Levet-Trafit, B.3
Martin, J.R.4
Poli, S.5
Porter, R.H.6
Bos, M.7
-
44
-
-
51749091526
-
Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT(6) receptor antagonist: Comparison among antipsychotics
-
1:CAS:528:DC%2BD1cXhtFWhs7zO 18094666 10.1038/sj.npp.1301654
-
Rodefer JS, Nguyen TN, Karlsson JJ, Arnt J (2008) Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT(6) receptor antagonist: comparison among antipsychotics. Neuropsychopharmacology 33:2657-2666
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 2657-2666
-
-
Rodefer, J.S.1
Nguyen, T.N.2
Karlsson, J.J.3
Arnt, J.4
-
45
-
-
33645358358
-
A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction: Molecular, cellular, functional and behavioral abnormalities
-
1:CAS:528:DC%2BD28XjtFaju7c%3D 16427029 10.1016/j.biopsych.2005.08.029
-
Rujescu D, Bender A, Keck M, Hartmann AM, Ohl F, Raeder H, Giegling I, Genius J, McCarley RW, Moller HJ, Grunze H (2006) A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction: molecular, cellular, functional and behavioral abnormalities. Biol Psychiat 59:721-729
-
(2006)
Biol Psychiat
, vol.59
, pp. 721-729
-
-
Rujescu, D.1
Bender, A.2
Keck, M.3
Hartmann, A.M.4
Ohl, F.5
Raeder, H.6
Giegling, I.7
Genius, J.8
McCarley, R.W.9
Moller, H.J.10
Grunze, H.11
-
46
-
-
69349100072
-
Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities
-
1:CAS:528:DC%2BD1MXhtFSns77N 19549510 10.1016/j.bcp.2009.06.021
-
Schaffhauser H, Mathiasen JR, Dicamillo A, Huffman MJ, Lu LD, McKenna BA, Qian J, Marino MJ (2009) Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities. Biochem Pharmacol 78:1035-1042
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 1035-1042
-
-
Schaffhauser, H.1
Mathiasen, J.R.2
Dicamillo, A.3
Huffman, M.J.4
Lu, L.D.5
McKenna, B.A.6
Qian, J.7
Marino, M.J.8
-
47
-
-
33846366685
-
Effects of the novel 5-HT(6) receptor antagonist RO4368554 in rat models for cognition and sensorimotor gating
-
1:CAS:528:DC%2BD2sXpvVyguw%3D%3D 16989988 10.1016/j.euroneuro.2006.06.009
-
Schreiber R, Vivian J, Hedley L, Szczepanski K, Secchi RL, Zuzow M, van Laarhoven S, Moreau JL, Martin JR, Sik A, Blokland A (2007) Effects of the novel 5-HT(6) receptor antagonist RO4368554 in rat models for cognition and sensorimotor gating. Eur Neuropsychopharmacol 17:277-288
-
(2007)
Eur Neuropsychopharmacol
, vol.17
, pp. 277-288
-
-
Schreiber, R.1
Vivian, J.2
Hedley, L.3
Szczepanski, K.4
Secchi, R.L.5
Zuzow, M.6
Van Laarhoven, S.7
Moreau, J.L.8
Martin, J.R.9
Sik, A.10
Blokland, A.11
-
48
-
-
0346023029
-
Role of the medial prefrontal cortex in N-methyl-D-aspartate receptor antagonist induced sensorimotor gating deficit in rats
-
1:CAS:528:DC%2BD2cXjsFSgsA%3D%3D 14729221 10.1016/j.neulet.2003.10.028
-
Schwabe K, Koch M (2004) Role of the medial prefrontal cortex in N-methyl-D-aspartate receptor antagonist induced sensorimotor gating deficit in rats. Neurosci Lett 355:5-8
-
(2004)
Neurosci Lett
, vol.355
, pp. 5-8
-
-
Schwabe, K.1
Koch, M.2
-
49
-
-
0030426257
-
Seroquel restores sensorimotor gating in phencyclidine-treated rats
-
1:CAS:528:DyaK2sXmslKk 8968353
-
Swerdlow NR, Bakshi V, Geyer MA (1996) Seroquel restores sensorimotor gating in phencyclidine-treated rats. J Pharmacol Exp Ther 279:1290-1299
-
(1996)
J Pharmacol Exp Ther
, vol.279
, pp. 1290-1299
-
-
Swerdlow, N.R.1
Bakshi, V.2
Geyer, M.A.3
-
50
-
-
0033938877
-
Animal models of deficient sensorimotor gating: What we know, what we think we know, and what we hope to know soon
-
1:STN:280:DC%2BD3M%2FltVKkug%3D%3D 11103873 10.1097/00008877-200006000- 00002
-
Swerdlow NR, Braff DL, Geyer MA (2000) Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon. Behav Pharmacol 11:185-204
-
(2000)
Behav Pharmacol
, vol.11
, pp. 185-204
-
-
Swerdlow, N.R.1
Braff, D.L.2
Geyer, M.A.3
-
51
-
-
0034927844
-
Neural circuit regulation of prepulse inhibition of startle in the rat: Current knowledge and future challenges
-
1:CAS:528:DC%2BD3MXmtlCqtbs%3D 10.1007/s002130100799
-
Swerdlow NR, Geyer MA, Braff DL (2001) Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology (Berl) 156:194-215
-
(2001)
Psychopharmacology (Berl)
, vol.156
, pp. 194-215
-
-
Swerdlow, N.R.1
Geyer, M.A.2
Braff, D.L.3
-
52
-
-
46749118971
-
5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease
-
1:CAS:528:DC%2BD1cXhtVOgtLrJ 18625457 10.1016/j.nurt.2008.05.008
-
Upton N, Chuang TT, Hunter AJ, Virley DJ (2008) 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease. Neurotherapeutics 5:458-469
-
(2008)
Neurotherapeutics
, vol.5
, pp. 458-469
-
-
Upton, N.1
Chuang, T.T.2
Hunter, A.J.3
Virley, D.J.4
-
53
-
-
0028834467
-
Reversal of dizocilpine-induced disruption of prepulse inhibition of an acoustic startle response by the 5-HT2 receptor antagonist ketanserin
-
1:CAS:528:DyaK2MXpslKisrc%3D 8749037 10.1016/0014-2999(95)00660-5
-
Varty GB, Higgins GA (1995) Reversal of dizocilpine-induced disruption of prepulse inhibition of an acoustic startle response by the 5-HT2 receptor antagonist ketanserin. Eur J Pharmacol 287:201-205
-
(1995)
Eur J Pharmacol
, vol.287
, pp. 201-205
-
-
Varty, G.B.1
Higgins, G.A.2
-
54
-
-
0033017227
-
M100907, a serotonin 5-HT2a receptor antagonist and putative antipsychotic, blocks dizocilpine-induced prepulse inhibition deficits in Sprague-Dawley and wistar rats
-
1:CAS:528:DyaK1MXitVSntbo%3D 10088132 10.1016/S0893-133X(98)00072-4
-
Varty GB, Bakshi VP, Geyer MA (1999) M100907, a serotonin 5-HT2a receptor antagonist and putative antipsychotic, blocks dizocilpine-induced prepulse inhibition deficits in Sprague-Dawley and wistar rats. Neuropsychopharmacology 20:311-321
-
(1999)
Neuropsychopharmacology
, vol.20
, pp. 311-321
-
-
Varty, G.B.1
Bakshi, V.P.2
Geyer, M.A.3
|