Effect of the 5-HT6 receptor antagonists Ro 04-6790 and Ro 65-7199 on latent inhibition and prepulse inhibition in the rat: Comparison to clozapine

Pharmacology Biochemistry and Behavior

Volumn 75, Issue 2, 2003, Pages 281-288

  Leng, Andreas ^a   Ouagazzal, Abdel ^b   Feldon, Joram ^a   Higgins, Guy A ^b  

^a ETH ZURICH   (Switzerland)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Conditioned lick suppression; Latent inhibition; Prepulse inhibition; Rat; Schizophrenia

Indexed keywords

4 AMINO N (6 BROMO 1H INDOL 4 YL)BENZENESULFONAMIDE; 4 AMINO N [2,6 BIS(METHYLAMINO) 4 PYRIMIDINYL]BENZENESULFONAMIDE; APOMORPHINE; CLOZAPINE; LYSERGIDE; RO 65 7199; SEROTONIN 6 RECEPTOR; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG; ACETYLCHOLINE; AMINO ACID RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR BLOCKING AGENT; NEUROLEPTIC AGENT; PHENCYCLIDINE; PYRIMIDINE DERIVATIVE; RO 4 6790; RO 4-6790; SEROTONIN RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; LATENT INHIBITION; LICKING; MALE; NONHUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME; ANIMAL; AVOIDANCE BEHAVIOR; BRAIN CORTEX; COMPARATIVE STUDY; DOSE RESPONSE; HIPPOCAMPUS; MAZE TEST; MEMORY; METABOLISM; STARTLE REFLEX; WISTAR RAT;

ACETYLCHOLINE; ANIMALS; ANTIPSYCHOTIC AGENTS; APOMORPHINE; AVOIDANCE LEARNING; CEREBRAL CORTEX; CLOZAPINE; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; HIPPOCAMPUS; LYSERGIC ACID DIETHYLAMIDE; MALE; MAZE LEARNING; MEMORY; PHENCYCLIDINE; PYRIMIDINES; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; STARTLE REACTION;

EID: 0038107717     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(03)00082-0     Document Type: Article

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