-
1
-
-
18244402941
-
A unified nomenclature for the superfamily of TRP cation channels
-
Montell, C., Birnbaumer, L., Flockerzi, V., Bindels, R.J., Bruford, E.A., Caterina, M.J., Clapham, D.E., Harteneck, C., Heller, S., Julius, D. et al. (2002) A unified nomenclature for the superfamily of TRP cation channels. Mol. Cell, 9, 229-231.
-
(2002)
Mol. Cell
, vol.9
, pp. 229-231
-
-
Montell, C.1
Birnbaumer, L.2
Flockerzi, V.3
Bindels, R.J.4
Bruford, E.A.5
Caterina, M.J.6
Clapham, D.E.7
Harteneck, C.8
Heller, S.9
Julius, D.10
-
2
-
-
84875422211
-
TRPV1 and TRPA1 antagonists prevent the transition of acute to chronic inflammation and pain in chronic pancreatitis
-
Schwartz, E.S., La, J.H., Scheff, N.N., Davis, B.M., Albers, K.M. and Gebhart, G.F. (2013) TRPV1 and TRPA1 antagonists prevent the transition of acute to chronic inflammation and pain in chronic pancreatitis. J. Neurosci., 33, 5603-5611.
-
(2013)
J. Neurosci.
, vol.33
, pp. 5603-5611
-
-
Schwartz, E.S.1
La, J.H.2
Scheff, N.N.3
Davis, B.M.4
Albers, K.M.5
Gebhart, G.F.6
-
3
-
-
84866484868
-
Positive allosteric modulation of TRPV1 as a novel analgesic mechanism
-
Lebovitz, E.E., Keller, J.M., Kominsky, H., Kaszas, K., Maric, D. and Iadarola, M.J. (2012) Positive allosteric modulation of TRPV1 as a novel analgesic mechanism. Mol. Pain, 8, 70.
-
(2012)
Mol. Pain
, vol.8
, pp. 70
-
-
Lebovitz, E.E.1
Keller, J.M.2
Kominsky, H.3
Kaszas, K.4
Maric, D.5
Iadarola, M.J.6
-
4
-
-
84874645499
-
TRP channels and analgesia
-
Premkumar, L.S. and Abooj, M. (2013) TRP channels and analgesia. Life Sci., 92, 415-424.
-
(2013)
Life Sci.
, vol.92
, pp. 415-424
-
-
Premkumar, L.S.1
Abooj, M.2
-
5
-
-
84859886840
-
Modulation of thermoreceptor TRPM8 by cooling compounds
-
Bharate, S.S. and Bharate, S.B. (2012) Modulation of thermoreceptor TRPM8 by cooling compounds. ACS Chem. Neurosci., 3, 248-267.
-
(2012)
ACS Chem. Neurosci.
, vol.3
, pp. 248-267
-
-
Bharate, S.S.1
Bharate, S.B.2
-
6
-
-
84882991358
-
Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin
-
Selescu, T., Ciobanu, A.C., Dobre, C., Reid, G. and Babes, A. (2013) Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin. Chem. Senses., 38, 563-575.
-
(2013)
Chem. Senses.
, vol.38
, pp. 563-575
-
-
Selescu, T.1
Ciobanu, A.C.2
Dobre, C.3
Reid, G.4
Babes, A.5
-
7
-
-
84874650819
-
TRPM8 ion channel ligands for new therapeutic applications and as probes to study menthol pharmacology
-
Journigan, V.B. and Zaveri, N.T. (2013) TRPM8 ion channel ligands for new therapeutic applications and as probes to study menthol pharmacology. Life Sci., 92, 425-437.
-
(2013)
Life Sci.
, vol.92
, pp. 425-437
-
-
Journigan, V.B.1
Zaveri, N.T.2
-
8
-
-
77953109127
-
Reversal of dose-limiting carboplatin-induced peripheral neuropathy with TRPM8 activator, menthol, enables further effective chemotherapy delivery
-
Storey, D.J., Colvin, L.A., Mackean, M.J., Mitchell, R., Fleetwood-Walker, S.M. and Fallon, M.T. (2010) Reversal of dose-limiting carboplatin-induced peripheral neuropathy with TRPM8 activator, menthol, enables further effective chemotherapy delivery. J. Pain Symptom. Manage., 39, e2-e4.
-
(2010)
J. Pain Symptom. Manage.
, vol.39
-
-
Storey, D.J.1
Colvin, L.A.2
MacKean, M.J.3
Mitchell, R.4
Fleetwood-Walker, S.M.5
Fallon, M.T.6
-
9
-
-
84881660347
-
TRPA1 insensitivity of human sural nerve axons after exposure to lidocaine
-
Docherty, R.J., Ginsberg, L., Jadoon, S., Orrell, R.W. and Bhattacharjee, A. (2013) TRPA1 insensitivity of human sural nerve axons after exposure to lidocaine. Pain, 154, 1569-1577.
-
(2013)
Pain
, vol.154
, pp. 1569-1577
-
-
Docherty, R.J.1
Ginsberg, L.2
Jadoon, S.3
Orrell, R.W.4
Bhattacharjee, A.5
-
10
-
-
84879622275
-
A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain
-
Nativi, C., Gualdani, R., Dragoni, E., Di Cesare Mannelli, L., Sostegni, S., Norcini, M., Gabrielli, G., la Marca, G., Richichi, B., Francesconi, O. et al. (2013) A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain. Sci. Rep., 3, 2005.
-
(2013)
Sci. Rep
, pp. 3
-
-
Nativi, C.1
Gualdani, R.2
Dragoni, E.3
Di Cesare Mannelli, L.4
Sostegni, S.5
Norcini, M.6
Gabrielli, G.7
La Marca, G.8
Richichi, B.9
Francesconi, O.10
-
11
-
-
33745153776
-
The cardiac hERG/IKr potassium channel as pharmacological target: Structure, function, regulation, and clinical applications
-
Thomas, D., Karle, C.A. and Kiehn, J. (2006) The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications. Curr. Pharm. Des., 12, 2271-2283.
-
(2006)
Curr. Pharm. Des.
, vol.12
, pp. 2271-2283
-
-
Thomas, D.1
Karle, C.A.2
Kiehn, J.3
-
12
-
-
77249138349
-
Toward a consensus model of the HERG potassium channel
-
Stary, A., Wacker, S.J., Boukharta, L., Zachariae, U., Karimi-Nejad, Y., Aqvist, J., Vriend, G. and de Groot, B.L. (2010) Toward a consensus model of the HERG potassium channel. Chem. Med. Chem., 5, 455-467.
-
(2010)
Chem. Med. Chem.
, vol.5
, pp. 455-467
-
-
Stary, A.1
Wacker, S.J.2
Boukharta, L.3
Zachariae, U.4
Karimi-Nejad, Y.5
Aqvist, J.6
Vriend, G.7
De Groot, B.L.8
-
13
-
-
84867830194
-
Modeling of open, closed, and open-inactivated states of the hERG1 channel: Structural mechanisms of the state-dependent drug binding
-
Durdagi, S., Deshpande, S., Duff, H.J. and Noskov, S.Y. (2012) Modeling of open, closed, and open-inactivated states of the hERG1 channel: structural mechanisms of the state-dependent drug binding. J. Chem. Inf. Model, 52, 2760-2774.
-
(2012)
J. Chem. Inf. Model
, vol.52
, pp. 2760-2774
-
-
Durdagi, S.1
Deshpande, S.2
Duff, H.J.3
Noskov, S.Y.4
-
14
-
-
84878403944
-
Indexing molecules for their hERG liability
-
Rayan, A., Falah, M., Raiyn, J., Da'adoosh, B., Kadan, S., Zaid, H. and Goldblum, A. (2013) Indexing molecules for their hERG liability. Eur. J. Med. Chem., 65C, 304-314.
-
(2013)
Eur. J. Med. Chem.
, vol.65 C
, pp. 304-314
-
-
Rayan, A.1
Falah, M.2
Raiyn, J.3
Da'Adoosh, B.4
Kadan, S.5
Zaid, H.6
Goldblum, A.7
-
15
-
-
77949896163
-
Familial pain syndromes from mutations of the NaV1.7 sodium channel
-
Fischer, T.Z. and Waxman, S.G. (2010) Familial pain syndromes from mutations of the NaV1.7 sodium channel. Ann. N. Y. Acad. Sci., 1184, 196-207.
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1184
, pp. 196-207
-
-
Fischer, T.Z.1
Waxman, S.G.2
-
16
-
-
84881237059
-
Designing a C84 fullerene as a specific voltage-gated sodium channel blocker
-
Hilder, T.A. and Chung, S.H. (2013) Designing a C84 fullerene as a specific voltage-gated sodium channel blocker. Nanoscale Res. Lett., 8, 323.
-
(2013)
Nanoscale Res. Lett.
, vol.8
, pp. 323
-
-
Hilder, T.A.1
Chung, S.H.2
-
17
-
-
78651307693
-
VKCDB: Voltage-gated K+ channel database updated and upgraded
-
Gallin, W.J. and Boutet, P.A. (2011) VKCDB: voltage-gated K+ channel database updated and upgraded. Nucleic Acids Res., 39, D362-D366.
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Gallin, W.J.1
Boutet, P.A.2
-
18
-
-
84867414333
-
TRIP database 2.0: A manually curated information hub for accessing TRP channel interaction network
-
Shin, Y.C., Shin, S.Y., Chun, J.N., Cho, H.S., Lim, J.M., Kim, H.G., So, I., Kwon, D. and Jeon, J.H. (2012) TRIP database 2.0: a manually curated information hub for accessing TRP channel interaction network. PLoS One, 7, e47165.
-
(2012)
PLoS One
, vol.7
-
-
Shin, Y.C.1
Shin, S.Y.2
Chun, J.N.3
Cho, H.S.4
Lim, J.M.5
Kim, H.G.6
So, I.7
Kwon, D.8
Jeon, J.H.9
-
19
-
-
84864486886
-
MOLEonline 2.0: Interactive web-based analysis of biomacromolecular channels
-
Berka, K., Hanak, O., Sehnal, D., Banas, P., Navratilova, V., Jaiswal, D., Ionescu, C.M., Svobodova Varekova, R., Koca, J. and Otyepka, M. (2012) MOLEonline 2.0: interactive web-based analysis of biomacromolecular channels. Nucleic Acids Res., 40, W222-W227.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Berka, K.1
Hanak, O.2
Sehnal, D.3
Banas, P.4
Navratilova, V.5
Jaiswal, D.6
Ionescu, C.M.7
Svobodova Varekova, R.8
Koca, J.9
Otyepka, M.10
-
20
-
-
84876350392
-
IUPHAR-DB: Updated database content and new features
-
Sharman, J.L., Benson, H.E., Pawson, A.J., Lukito, V., Mpamhanga, C.P., Bombail, V., Davenport, A.P., Peters, J.A., Spedding, M. and Harmar, A.J. (2013) IUPHAR-DB: updated database content and new features. Nucleic Acids Res., 41, D1083-D1088.
-
(2013)
Nucleic Acids Res.
, vol.41
-
-
Sharman, J.L.1
Benson, H.E.2
Pawson, A.J.3
Lukito, V.4
Mpamhanga, C.P.5
Bombail, V.6
Davenport, A.P.7
Peters, J.A.8
Spedding, M.9
Harmar, A.J.10
-
21
-
-
75549087817
-
An overview of the PubChem BioAssay resource
-
Wang, Y., Bolton, E., Dracheva, S., Karapetyan, K., Shoemaker, B.A., Suzek, T.O., Wang, J., Xiao, J., Zhang, J. and Bryant, S.H. (2010) An overview of the PubChem BioAssay resource. Nucleic Acids Res., 38, D255-D266.
-
(2010)
Nucleic Acids Res.
, vol.38
-
-
Wang, Y.1
Bolton, E.2
Dracheva, S.3
Karapetyan, K.4
Shoemaker, B.A.5
Suzek, T.O.6
Wang, J.7
Xiao, J.8
Zhang, J.9
Bryant, S.H.10
-
22
-
-
33846108633
-
BindingDB: A web-accessible database of experimentally determined protein-ligand binding affinities
-
Liu, T., Lin, Y., Wen, X., Jorissen, R.N. and Gilson, M.K. (2007) BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities. Nucleic Acids Res., 35, D198-D201.
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Liu, T.1
Lin, Y.2
Wen, X.3
Jorissen, R.N.4
Gilson, M.K.5
-
23
-
-
0035173371
-
The PDB data uniformity project
-
Bhat, T.N., Bourne, P., Feng, Z., Gilliland, G., Jain, S., Ravichandran, V., Schneider, B., Schneider, K., Thanki, N., Weissig, H. et al. (2001) The PDB data uniformity project. Nucleic Acids Res., 29, 214-218.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 214-218
-
-
Bhat, T.N.1
Bourne, P.2
Feng, Z.3
Gilliland, G.4
Jain, S.5
Ravichandran, V.6
Schneider, B.7
Schneider, K.8
Thanki, N.9
Weissig, H.10
-
24
-
-
78449284386
-
Pre-calculated protein structure alignments at the RCSB PDB website
-
Prlic, A., Bliven, S., Rose, P.W., Bluhm, W.F., Bizon, C., Godzik, A. and Bourne, P.E. (2010) Pre-calculated protein structure alignments at the RCSB PDB website. Bioinformatics, 26, 2983-2985.
-
(2010)
Bioinformatics
, vol.26
, pp. 2983-2985
-
-
Prlic, A.1
Bliven, S.2
Rose, P.W.3
Bluhm, W.F.4
Bizon, C.5
Godzik, A.6
Bourne, P.E.7
-
25
-
-
80054911951
-
LigPlot+: Multiple ligand-protein interaction diagrams for drug discovery
-
Laskowski, R.A. and Swindells, M.B. (2011) LigPlot+: multiple ligand-protein interaction diagrams for drug discovery. J. Chem. Inf. Model, 51, 2778-2786.
-
(2011)
J. Chem. Inf. Model
, vol.51
, pp. 2778-2786
-
-
Laskowski, R.A.1
Swindells, M.B.2
-
26
-
-
53849108437
-
Molecular modeling of the full-length human TRPV1 channel in closed and desensitized states
-
Fernandez-Ballester, G. and Ferrer-Montiel, A. (2008) Molecular modeling of the full-length human TRPV1 channel in closed and desensitized states. J. Membr. Biol., 223, 161-172.
-
(2008)
J. Membr. Biol.
, vol.223
, pp. 161-172
-
-
Fernandez-Ballester, G.1
Ferrer-Montiel, A.2
-
27
-
-
34548813656
-
Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH
-
Jasti, J., Furukawa, H., Gonzales, E.B. and Gouaux, E. (2007) Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH. Nature, 449, 316-323.
-
(2007)
Nature
, vol.449
, pp. 316-323
-
-
Jasti, J.1
Furukawa, H.2
Gonzales, E.B.3
Gouaux, E.4
-
28
-
-
84867851768
-
Black mamba venom peptides target acid-sensing ion channels to abolish pain
-
Diochot, S., Baron, A., Salinas, M., Douguet, D., Scarzello, S., Dabert-Gay, A.S., Debayle, D., Friend, V., Alloui, A., Lazdunski, M. et al. (2012) Black mamba venom peptides target acid-sensing ion channels to abolish pain. Nature, 490, 552-555.
-
(2012)
Nature
, vol.490
, pp. 552-555
-
-
Diochot, S.1
Baron, A.2
Salinas, M.3
Douguet, D.4
Scarzello, S.5
Dabert-Gay, A.S.6
Debayle, D.7
Friend, V.8
Alloui, A.9
Lazdunski, M.10
-
29
-
-
84857320547
-
Putative binding sites, and pathways to them, for amidine and guanidine current inhibitors on acid-sensing ion channels (ASIC). A theoretical approach with hASIC1a homology model
-
Pietra, F. (2012) Putative binding sites, and pathways to them, for amidine and guanidine current inhibitors on acid-sensing ion channels (ASIC). A theoretical approach with hASIC1a homology model. Chem. Biodivers., 9, 331-351.
-
(2012)
Chem. Biodivers.
, vol.9
, pp. 331-351
-
-
Pietra, F.1
-
30
-
-
84875426837
-
P2X receptors as drug targets
-
North, R.A. and Jarvis, M.F. (2013) P2X receptors as drug targets. Mol. Pharmacol., 83, 759-769.
-
(2013)
Mol. Pharmacol.
, vol.83
, pp. 759-769
-
-
North, R.A.1
Jarvis, M.F.2
-
31
-
-
84857783443
-
TRESK: The lone ranger of two-pore domain potassium channels
-
Enyedi, P., Braun, G. and Czirjak, G. (2012) TRESK: the lone ranger of two-pore domain potassium channels. Mol. Cell Endocrinol., 353, 75-81.
-
(2012)
Mol. Cell Endocrinol.
, vol.353
, pp. 75-81
-
-
Enyedi, P.1
Braun, G.2
Czirjak, G.3
-
32
-
-
80053343313
-
Migraine: Role of the TRESK two-pore potassium channel
-
Lafreniere, R.G. and Rouleau, G.A. (2011) Migraine: role of the TRESK two-pore potassium channel. Int. J. Biochem. Cell Biol., 43, 1533-1536.
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 1533-1536
-
-
Lafreniere, R.G.1
Rouleau, G.A.2
-
33
-
-
33745741107
-
TREK-1, a K+ channel involved in polymodal pain perception
-
Alloui, A., Zimmermann, K., Mamet, J., Duprat, F., Noel, J., Chemin, J., Guy, N., Blondeau, N., Voilley, N., Rubat-Coudert, C. et al. (2006) TREK-1, a K+ channel involved in polymodal pain perception. Embo J., 25, 2368-2376.
-
(2006)
Embo J.
, vol.25
, pp. 2368-2376
-
-
Alloui, A.1
Zimmermann, K.2
Mamet, J.3
Duprat, F.4
Noel, J.5
Chemin, J.6
Guy, N.7
Blondeau, N.8
Voilley, N.9
Rubat-Coudert, C.10
-
34
-
-
33646024354
-
Physiology and pharmacology of the vanilloid receptor
-
Messeguer, A., Planells-Cases, R. and Ferrer-Montiel, A. (2006) Physiology and pharmacology of the vanilloid receptor. Curr. Neuropharmacol., 4, 1-15.
-
(2006)
Curr. Neuropharmacol.
, vol.4
, pp. 1-15
-
-
Messeguer, A.1
Planells-Cases, R.2
Ferrer-Montiel, A.3
-
35
-
-
74549138165
-
Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist
-
Cascio, M.G., Gauson, L.A., Stevenson, L.A., Ross, R.A. and Pertwee, R.G. (2010) Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. Br. J. Pharmacol., 159, 129-141.
-
(2010)
Br. J. Pharmacol.
, vol.159
, pp. 129-141
-
-
Cascio, M.G.1
Gauson, L.A.2
Stevenson, L.A.3
Ross, R.A.4
Pertwee, R.G.5
-
36
-
-
0021698714
-
Intraocular pressure, ocular toxicity and neurotoxicity after administration of cannabinol or cannabigerol
-
Colasanti, B.K., Craig, C.R. and Allara, R.D. (1984) Intraocular pressure, ocular toxicity and neurotoxicity after administration of cannabinol or cannabigerol. Exp. Eye Res., 39, 251-259.
-
(1984)
Exp. Eye Res.
, vol.39
, pp. 251-259
-
-
Colasanti, B.K.1
Craig, C.R.2
Allara, R.D.3
-
37
-
-
84875726038
-
Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease
-
Borrelli, F., Fasolino, I., Romano, B., Capasso, R., Maiello, F., Coppola, D., Orlando, P., Battista, G., Pagano, E., Di Marzo, V. et al. (2013) Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. Biochem. Pharmacol., 85, 1306-1316.
-
(2013)
Biochem. Pharmacol.
, vol.85
, pp. 1306-1316
-
-
Borrelli, F.1
Fasolino, I.2
Romano, B.3
Capasso, R.4
Maiello, F.5
Coppola, D.6
Orlando, P.7
Battista, G.8
Pagano, E.9
Di Marzo, V.10
-
38
-
-
44249117614
-
Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8
-
De Petrocellis, L., Vellani, V., Schiano-Moriello, A., Marini, P., Magherini, P.C., Orlando, P. and Di Marzo, V. (2008) Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8. J. Pharmacol. Exp. Ther., 325, 1007-1015.
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.325
, pp. 1007-1015
-
-
De Petrocellis, L.1
Vellani, V.2
Schiano-Moriello, A.3
Marini, P.4
Magherini, P.C.5
Orlando, P.6
Di Marzo, V.7
|