Reversal of Dose-Limiting Carboplatin-Induced Peripheral Neuropathy with TRPM8 Activator, Menthol, Enables Further Effective Chemotherapy Delivery

Journal of Pain and Symptom Management

Volumn 39, Issue 6, 2010, Pages

  Storey, Dawn J ^a,b   Colvin, Lesley A ^b   Mackean, Melanie J ^b   Mitchell, Rory ^a   Fleetwood Walker, Susan M ^a   Fallon, Marie T ^a,b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; CA 125 ANTIGEN; CARBOPLATIN; MENTHOL; PACLITAXEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8;

AGED; ALLODYNIA; ANALGESIA; CANCER COMBINATION CHEMOTHERAPY; CANCER PAIN; CANCER PATIENT; CANCER STAGING; CASE REPORT; DIABETES MELLITUS; DRUG DOSE INCREASE; EVENING DOSAGE; FEMALE; HAND PARESTHESIA; HUMAN; LETTER; MULTIPLE CYCLE TREATMENT; NECK PAIN; NEUROTOXICITY; OVARY CANCER; PAIN ASSESSMENT; PARESTHESIA; PERIPHERAL NEUROPATHY; TREATMENT RESPONSE; VISUAL ANALOG SCALE; WEAKNESS;

AGED; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARBOPLATIN; FEMALE; HUMANS; METHANOL; OVARIAN NEOPLASMS; PACLITAXEL; PAIN MEASUREMENT; PERIPHERAL NERVOUS SYSTEM DISEASES; TRPM CATION CHANNELS;

EID: 77953109127     PISSN: 08853924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2010.02.004     Document Type: Letter

References (2)

1. Proudfoot C.J., Garry E.M., Cottrell D.F., et al. Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain. Curr Biol 16 (2006) 1591-1605
2. Colvin L.A., Johnson P.R.E., Mitchell R., Fleetwood-Walker S.M., and Fallon M.T. From bench to bedside: a case of rapid reversal of bortezomib-induced neuropathic pain by the TRPM8 activator, Menthol. J Clin Oncol 26 (2008) 4519-4520