The structure of CD4

Current Topics in Microbiology and Immunology

Volumn 205, Issue , 1996, Pages

  Brady, R L ^a   Barclay, A N ^b  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 11944260700     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (49)

1. Ashford DA, Alafi CD, Gamble VM, Mackay DJ, Rademacher TW, Williams PJ, Dwek RA, Barclay AN, Davis SJ, Somoza C, Ward HA, Williams AF (1993) Site specific glycosylation of recombinant rat and human soluble CD4 variants expressed in Chinese hamster ovary cells J Biol Chem 268 3260-3267
2. Baixeras E, Huard B, Miossec C, Jitsukawa S, Martin M, Hercend T, Auffray C, Triebel F, Piatier TD (1992) Characterization of the lymphocyte activation gene 3-encoded protein A new ligand for human leukocyte antigen class II antigens. J Exp Med 176 327-337
3. Barclay AN, Brady RL, Davis SJ, Lange G (1993) CD4 and the immunoglobulin superfamily Philos Trans R Soc Lond Biol 342: 7-12
4. Bernard A, Boumsell L, Dausset J, Milstein C, Schlossman SF (1984) Leucocyte typing. Springer, Berlin Heidelberg New York
5. Brady RL, Dodson EJ, Dodson GG, Lange G, Davis SJ, Williams AF, Barclay AN (1993) Crystal structure of domains 3 and 4 of rat CD4, relation to the NH2-terminal domains Science 260 979-983
6. Brostoff SW, Mason DW (1984) Experimental allergic encephatomyelitis successful treatment in vivo with a monoclonal antibody that recognizes T helper cells J Immunol 133 1938-1942
7. Brown JH, Jardetsky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC (1993) Three-dimensional structure of the human class II histocompatibility antigen HLA-DRI Nature 364: 33-39
8. Cammarota G, Scheirie A, Takacs B, Doran DM, Knorr R, Bannwarth W, Guardiola J, Sinigaglia F(1992) Identification of a CD4 binding site on the beta 2 domain of HLA-DR molecules. Nature 356. 799-801
9. Clark SJ, Jefferies WA, Barclay AN, Gagnon J, Williams AF (1987) Peptide and nucleotide sequences of rat CD4 (W3/25) antigen: evidence for derivation from a structure with four immunoglobulin-related domains Proc Natl Acad Sci USA 84: 1649-1653
10. Dalgleish AG, Beverley PC, Clapham PR, Crawford DH, Greaves MF, Weiss RA (1984) The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature 312: 763-767
11. Davis SJ, Brady RL, Barclay AN, Harlos K, Dodson GG, Williams AF (1990a) Crystallization of a soluble form of the rat T-cell surface glycoprotein CD4 complexed with Fab from the W3/25 monoclonal antibody J Mol Biol 213: 7-10
12. Davis SJ, Ward HA, Puklavec MJ, Willis AC, Williams AF, Barclay AN (1990b) High level expression in Chinese hamster ovary cells of soluble forms of CD4 T lymphocyte glycoprotein including glycosylation variants. J Biol Chem 265: 10410-10418
13. Doyle C, Strominger JL (1987) Interaction between CD4 and class II MHC molecules mediates cell adhesion. Nature 330 256-259
14. Fomsgaard A, Hirsch VM, Johnson PR(1992) Cloning and sequences of primate CD4 molecules diversity of the cellular receptor for simian immunodeficiency virus/human immunodeficiency virus. Eur J Immunol 22: 2973-2981
15. Garrett T, Wang J, Yan Y, Liu J, Harrison SC (1993) Refinement and analysis of the structure of the first two domains of human CD4 J Mol Biol 234: 763-778
16. Harpaz Y, Chothia C (1994) Many of the immunoglobulin superfamily domains in cell adhesion molecules and surface receptors belong to a new structural set which is close to that containing variable domains J Mol Biol 238 528-539
17. Houlgatte R, Scarmato P, Marhomy SE, Martin M, Ostankovitch M, Hatosse S, Vervisch A, Auffray C, Platier Tonnear D (1994) HLA class II antigens and the HIV envelope glycoprotein GP120 bind to the same face of CD4. J Immunol 152 4475-4488
18. Hussey RE, Richardson NE, Kowalski M, Brown NR, Chang HC, Siliciano RF, Dorfman T, Walker B, Sodroski J, Reinherz EL (1988) A soluble CD4 protein selectively inhibits HIV replication and syncytium formation. Nature 331: 78-81
19. Jones EY, Davis SJ, Williams AF, Harlos K, Stuart DI (1992) Crystal structure at 2.8 Å resolution of a soluble form of the cell adhesion molecule CD2 Nature 360: 232-239
20. Klatzmann D, Champagne E, Chamaret S, Gruest J, Guetard D, Hercend T, Gluckman JC, Montagnier L (1984) T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV Nature 312: 767-768
21. Kuchel PW, Campbell DG, Barclay AN, Williams AF (1978) Molecular weights of the Thy-1 glycoproteins from rat thymus and brain in the presence and absence of deoxycholate Biochem J 169 411-417
22. Kwong PD, Ryu SE, Hendrickson WA, Axel R, Sweet RM, Falena WG, Hensley P, Sweet RW (1990) Molecular characteristics of recombinant human CD4 as deduced from polymorphic crystals. Proc Natl Acad Sci USA 87 6423-6427
23. Lange G, Lewis SJ, Murshudov GN, Dodson GG, Moody PCE, Turkenburg JP, Barclay AN, Brady LR (1994) Crystal structure of an extracellular fragment of the rat CD4 receptor containing domains 3 and 4 Structure 2: 469-481
24. Langedijk J, Puijk WC, Van HW, Meloen RH (1993) Location of CD4 dimerization site explains critical role of CDR3-like region in HIV-1 infection and T-cell activation and implies a model for complex of coreceptor-MHC. J Biol Chem 268 16875-16878
25. Littman DR (1987) The structure of the CD4 and CD8 genes. Annu Rev Immunol 5 561-584
26. Maddon PJ, Littman DR, Godfrey M, Maddon DE, Chess L, Axel R (1985) The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4 a new member of the immunoglobulin gene family Cell 42: 93-104
27. Maddon PJ, Molineaux, SM, Maddon DE, Zimmerman KA, Godfrey M, Alt FW, Chess L, Axel R (1987) Structure and expression of the human and mouse T4 genes. Proc Natl Acad Sci USA 84. 9155-9159
28. Moebius U, Clayton LK, Abraham S, Harrison SC, Reinherz EL (1992) The human immunodeficiency virus gp120 binding site on CD4 Delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high-resolution CD4 atomic structure. J Exp Med 176 507-517
29. Nag B, Wada HG, Passmore D, Clark BR, Sharma SD, McConnell HM (1993) Purified beta-chain of MHC Class II binds to CD4 molecules on transfected HeLa cells J Immunol 150: 1358-1364
30. Pal R, Nair BC, Hoke GM, Sarngadharan MG, Edidin M (1991) Lateral diffusion of CD4 on a human neoplastic T-cell line probed with a fluorescent derivative of the envelope glycoprotein (gp120) of human immunodeficiency virus type 1 (HIV-1) J Cell Physiol 147: 326-332
31. Reinherz EL, Kung PC, Goldstein G, Schlssman SF (1979) Separation of functional subsets of human T cells by a monoclonal antibody. Proc Natl Acad Sci USA 76: 4061-4065
32. Rudd CE, Trevillyan JM, Dasgupta JD, Wong LL, Schlossman SF (1988) The CD4 receptor is compilxed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes. Proc Natl Acad Sci USA 85: 5190-5194
33. Ryu SE, Kwong PD, Truneh A, Porter TG, Arthos J, Rosenberg M, Dai XP, Xuong NH, Axel R, Sweet RW et al (1990) Crystal structure of an HIV-binding recombinant fragment of human CD4. Nature 348 419-426
34. Ryu SE, Truneh A, Sweet RW, Hendrickson WA (1994) Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices Structure 2. 59-74
35. Schockmel GA, Somoza C, Davis SJ, Williams AF, Healey D (1992) Construction of a binding site for human immunodeficiency virus type 1 gp120 in rat CD4. J Exp Med 175: 301-304
36. Spellman MW, Leonard CK, Basa LJ, Gelineo I, Van HH (1991) Carbohydrate structures of recombinant soluble human CD4 expressed in Chinese hamster ovary cells. Biochemistry 30: 2395-2406
37. Triebel F, Jitsukawa S, Baixeras E, Roman RS, Genevee C, Viegals PE, Hercend T (1990) LAG-3, a novel lymphocyte activation gene closely related to CD4 J Exp Med 171: 1393-1405
38. Tsui P, Sweet RW, Sathe G, Rosenberg M (1992) An efficient phage plaque screen for the random mutational analysis of the interaction of HIV-1 gp120 with human CD4. J Biol Chem 267. 9361-9367
39. van der Merwe PA, Brown MH, Davis SJ, Barclay AN (1993) Affinity and kinetic analysis of the interaction of the cell-adhesion molecules rat CD2 and CD48. EMBO J 12: 4945-4954
40. Veillette A, Sleckman BP, Ratnofsky S, Bolen JB, Burakoff SJ (1990) The cytoplasmic domain of CD4 is required for stable association with the lymphocyte-specific tyrosine protein kinase p56lck Eur J Immunol 20: 1397-1400
41. Vignali DAA, Doyle C, Kinch MS, Shin J, Strominger JL (1993) Interactions of CD4 with MHC class II molecules, T cell receptors and p56lck Phil Trans R Soc Lond B 342: 13-24
42. Wang JH, Yan YW, Garrett TP, Liu JF, Rodgers DW, Garlick RL, Tarr GE, Husain Y, Reinherz EL, Harrison SC (1990) Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains Nature 348, 411-418
43. Webb M, Mason DW, Williams AF (1979) Inhibition of mixed lymphocyte response by monoclonal antibody specific for a rat T lymphocyte subset Nature 282: 841-843
44. Weber S, Karjalainen K (1993) Mouse CD4 binds MHC class II with extremely low affinity Int Immunol 5: 695-698
45. White RA, Mason DW, Williams AF, Galfre G, Milstein C (1978) T-lymphocyte heterogeneity in the rat-separation of functional subpopulations using a monoclonal antibody. J Exp Med 148 664-673
46. Williams AF, Barclay AN (1988) The immunoglobulin superfamily - domains for cell surface recognition Annu Rev Immunol 6 381-405
47. Williams AF, Galfre G, Milstein C (1977) Analysis of cell surfaces by xenogeneic myetoma-hybrid antibodies: differentiation antigens of rat lymphocytes. Cell 12: 663-673
48. Williams AF, Davis SJ, He Q, Barclay AN (1989) Structural diversity in domains of the immunoglobulin superfamily. Cold Spring Harb Symp Quant Biol LIV. 637-647
49. Yuen CT, Carr SA, Feizi T (1990) The spectrum of N-linked oligosaccharide structures detected by enzymic microsequencing on a recombinant soluble CD4 glycoprotein from Chinese hamster ovary cells. Eur J Biochem 192: 523-528