-
1
-
-
33646575557
-
Inhibition of Fasmediated apoptosis through administration of soluble Fas receptor improves functional outcome and reduces posttraumatic axonal degeneration after acute spinal cord injury
-
Ackery A., Robins S, Fehlings MG. 2006. Inhibition of Fasmediated apoptosis through administration of soluble Fas receptor improves functional outcome and reduces posttraumatic axonal degeneration after acute spinal cord injury. J Neurotrauma 23: 604-616.
-
(2006)
J Neurotrauma
, vol.23
, pp. 604-616
-
-
Ackery, A.1
Robins, S.2
Fehlings, M.G.3
-
2
-
-
0027484072
-
Fas transduces activation signals in normal human T lymphocytes
-
Alderson M.R., Armitage RJ, Maraskovsky E, Tough TW, Roux E., Schooley K, Ramsdell F, Lynch DH. 1993. Fas transduces activation signals in normal human T lymphocytes. J Exp Med 178: 2231-2235.
-
(1993)
J Exp Med
, vol.178
, pp. 2231-2235
-
-
Alderson, M.R.1
Armitage, R.J.2
Maraskovsky, E.3
Tough, T.W.4
Roux, E.5
Schooley, K.6
Ramsdell, F.7
Lynch, D.H.8
-
3
-
-
0027988319
-
Regulation of apoptosis and T cell activation by Fas-specific mAb
-
Alderson M.R., Tough TW, Braddy S, Davis-Smith T, Roux E, Schooley K., Miller RE, Lynch DH. 1994. Regulation of apoptosis and T cell activation by Fas-specific mAb. Int Immunol 6: 1799-1806.
-
(1994)
Int Immunol
, vol.6
, pp. 1799-1806
-
-
Alderson, M.R.1
Tough, T.W.2
Braddy, S.3
Davis-Smith, T.4
Roux, E.5
Schooley, K.6
Miller, R.E.7
Lynch, D.H.8
-
4
-
-
0028909197
-
Fas ligand mediates activation-induced cell death in human T lymphocytes
-
Alderson M.R., Tough TW, Davis-Smith T, Braddy S, Falk B, Schooley K.A., Goodwin RG, Smith CA, Ramsdell F, Lynch DH. 1995. Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med 181: 71-77.
-
(1995)
J Exp Med
, vol.181
, pp. 71-77
-
-
Alderson, M.R.1
Tough, T.W.2
Davis-Smith, T.3
Braddy, S.4
Falk, B.5
Schooley, K.A.6
Goodwin, R.G.7
Smith, C.A.8
Ramsdell, F.9
Lynch, D.H.10
-
5
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
Ashkenazi A., Pai RC, Fong S, Leung S, Lawrence DA, Marsters SA, Blackie C, Chang L, McMurtrey AE, Hebert A, et al. 1999. Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 104: 155-162.
-
(1999)
J Clin Invest
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
Blackie, C.7
Chang, L.8
McMurtrey, A.E.9
Hebert, A.10
-
6
-
-
0029953810
-
The role of cell-mediated cytotoxicity in acuteGVHDafter MHCmatched allogeneic bone marrow transplantation in mice
-
Baker M.B., Altman NH, Podack ER, Levy RB. 1996. The role of cell-mediated cytotoxicity in acuteGVHDafter MHCmatched allogeneic bone marrow transplantation in mice. J Exp Med 183: 2645-2656.
-
(1996)
J Exp Med
, vol.183
, pp. 2645-2656
-
-
Baker, M.B.1
Altman, N.H.2
Podack, E.R.3
Levy, R.B.4
-
7
-
-
67349162130
-
Tumour necrosis factor and cancer
-
Balkwill F. 2009. Tumour necrosis factor and cancer. Nat Rev Cancer 9: 361-371.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 361-371
-
-
Balkwill, F.1
-
8
-
-
4143108125
-
CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells
-
Barnhart B.C., Legembre P, Pietras E, Bubici C, Franzoso G, Peter ME. 2004. CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells. EMBO J 23: 3175-3185.
-
(2004)
EMBO J
, vol.23
, pp. 3175-3185
-
-
Barnhart, B.C.1
Legembre, P.2
Pietras, E.3
Bubici, C.4
Franzoso, G.5
Peter, M.E.6
-
9
-
-
0028932731
-
The CTL's kiss of death
-
Berke G. 1995. The CTL's kiss of death. Cell 81: 9-12.
-
(1995)
Cell
, vol.81
, pp. 9-12
-
-
Berke, G.1
-
10
-
-
0030896087
-
TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)
-
Bodmer J.L., Burns K, Schneider P, Hofmann K, Steiner V, Thome M., Bornand T, Hahne M, Schroter M, Becker K, et al. 1997. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95). Immunity 6: 79-88.
-
(1997)
Immunity
, vol.6
, pp. 79-88
-
-
Bodmer, J.L.1
Burns, K.2
Schneider, P.3
Hofmann, K.4
Steiner, V.5
Thome, M.6
Bornand, T.7
Hahne, M.8
Schroter, M.9
Becker, K.10
-
11
-
-
0028985261
-
Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects
-
Boldin M.P., Mett IL, Varfolomeev EE, Chumakov I, Shemer-Avni Y., Camonis JH, Wallach D. 1995a. Self-association of the "death domains of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects. J Biol Chem 270: 387-391.
-
(1995)
J Biol Chem
, vol.270
, pp. 387-391
-
-
Boldin, M.P.1
Mett, I.L.2
Varfolomeev, E.E.3
Chumakov, I.4
Shemer-Avni, Y.5
Camonis, J.H.6
Wallach, D.7
-
12
-
-
0028913550
-
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
-
Boldin MP, Varfolomeev EE, Pancer Z, Mett IL, Camonis JH, Wallach D. 1995b. A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain. J Biol Chem 270: 7795-7798.
-
(1995)
J Biol Chem
, vol.270
, pp. 7795-7798
-
-
Boldin, M.P.1
Varfolomeev, E.E.2
Pancer, Z.3
Mett, I.L.4
Camonis, J.H.5
Wallach, D.6
-
13
-
-
0030011398
-
Involvement ofMACH, a novelMORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death
-
Boldin M.P., Goncharov TM, Goltsev YV, Wallach D. 1996. Involvement ofMACH, a novelMORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death. Cell 85: 803-815.
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
14
-
-
0030050453
-
Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease
-
Braun M.Y., Lowin B, French L, Acha-Orbea H, Tschopp J. 1996. Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease. J Exp Med 183: 657-661.
-
(1996)
J Exp Med
, vol.183
, pp. 657-661
-
-
Braun, M.Y.1
Lowin, B.2
French, L.3
Acha-Orbea, H.4
Tschopp, J.5
-
15
-
-
0028983657
-
Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
-
Brunner T., Mogil RJ, LaFace D, Yoo NJ, Mahboubi A, Echeverri F., Martin SJ, Force WR, Lynch DH, Ware CF, et al. 1995. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373: 441-444.
-
(1995)
Nature
, vol.373
, pp. 441-444
-
-
Brunner, T.1
Mogil, R.J.2
LaFace, D.3
Yoo, N.J.4
Mahboubi, A.5
Echeverri, F.6
Martin, S.J.7
Force, W.R.8
Lynch, D.H.9
Ware, C.F.10
-
16
-
-
33344476184
-
cFLIP regulation of lymphocyte activation and development
-
Budd R.C., Yeh WC, Tschopp J. 2006. cFLIP regulation of lymphocyte activation and development. Nat Rev Immunol 6: 196-204.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 196-204
-
-
Budd, R.C.1
Yeh, W.C.2
Tschopp, J.3
-
17
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
Carswell E.A., Old LJ, Kassel RL, Green S, Fiore N, Williamson B. 1975. An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci 72: 3666-3670.
-
(1975)
Proc Natl Acad Sci
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
Green, S.4
Fiore, N.5
Williamson, B.6
-
18
-
-
0026517239
-
Molecular cloning of the interleukin-1b converting enzyme
-
Cerretti D.P., Kozlosky CJ, Mosley B, Nelson N, Van Ness K, Greenstreet T.A., March CJ, Kronheim SR, Druck T, Cannizzaro L.A., et al. 1992. Molecular cloning of the interleukin-1b converting enzyme. Science 256: 97-100.
-
(1992)
Science
, vol.256
, pp. 97-100
-
-
Cerretti, D.P.1
Kozlosky, C.J.2
Mosley, B.3
Nelson, N.4
van Ness, K.5
Greenstreet, T.A.6
March, C.J.7
Kronheim, S.R.8
Druck, T.9
Cannizzaro, L.A.10
-
19
-
-
77952973860
-
CD95 promotes tumour growth
-
Chen L., Park SM, Tumanov AV, Hau A, Sawada K, Feig C, Turner J.R., Fu YX, Romero IL, Lengyel E, et al. 2010. CD95 promotes tumour growth. Nature 465: 492-496.
-
(2010)
Nature
, vol.465
, pp. 492-496
-
-
Chen, L.1
Park, S.M.2
Tumanov, A.V.3
Hau, A.4
Sawada, K.5
Feig, C.6
Turner, J.R.7
Fu, Y.X.8
Romero, I.L.9
Lengyel, E.10
-
20
-
-
0029026548
-
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
-
Chinnaiyan A.M., O'Rourke K, Tewari M, Dixit VM. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81: 505-512.
-
(1995)
Cell
, vol.81
, pp. 505-512
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Tewari, M.3
Dixit, V.M.4
-
21
-
-
10544236916
-
Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95
-
Chinnaiyan A.M., O'Rourke K, Yu GL, Lyons RH, Garg M, Duan D.R., Xing L, Gentz R, Ni J, Dixit VM. 1996. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 274: 990-992.
-
(1996)
Science
, vol.274
, pp. 990-992
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Yu, G.L.3
Lyons, R.H.4
Garg, M.5
Duan, D.R.6
Xing, L.7
Gentz, R.8
Ni, J.9
Dixit, V.M.10
-
22
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho Y.S., Challa S, Moquin D, Genga R, Ray TD, Guildford M, Chan FK. 2009. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137: 1112-1123.
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
Chan, F.K.7
-
23
-
-
0035213498
-
Caspases: Cellular demolition experts
-
Creagh E.M., Martin SJ. 2001. Caspases: Cellular demolition experts. Biochem Soc Trans 29: 696-702.
-
(2001)
Biochem Soc Trans
, vol.29
, pp. 696-702
-
-
Creagh, E.M.1
Martin, S.J.2
-
24
-
-
11144354396
-
Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury
-
Demjen D., Klussmann S, Kleber S, Zuliani C, Stieltjes B, Metzger C., Hirt UA, Walczak H, Falk W, Essig M, et al. 2004. Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury. Nat Med 10: 389-395.
-
(2004)
Nat Med
, vol.10
, pp. 389-395
-
-
Demjen, D.1
Klussmann, S.2
Kleber, S.3
Zuliani, C.4
Stieltjes, B.5
Metzger, C.6
Hirt, U.A.7
Walczak, H.8
Falk, W.9
Essig, M.10
-
25
-
-
0033835065
-
Fas engagement accelerates liver regeneration after partial hepatectomy
-
Desbarats J., Newell MK. 2000. Fas engagement accelerates liver regeneration after partial hepatectomy. Nat Med 6: 920-923.
-
(2000)
Nat Med
, vol.6
, pp. 920-923
-
-
Desbarats, J.1
Newell, M.K.2
-
27
-
-
0026482756
-
Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens
-
Dhein J., Daniel PT, Trauth BC, Oehm A, Moller P, Krammer PH. 1992. Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens. J Immunol 149: 3166-3173.
-
(1992)
J Immunol
, vol.149
, pp. 3166-3173
-
-
Dhein, J.1
Daniel, P.T.2
Trauth, B.C.3
Oehm, A.4
Moller, P.5
Krammer, P.H.6
-
28
-
-
0028795758
-
Autocrine T-cell suicide mediated by APO-1/(Fas/ CD95)
-
Dhein J., Walczak H, Baumler C, Debatin KM, Krammer PH. 1995. Autocrine T-cell suicide mediated by APO-1/(Fas/ CD95). Nature 373: 438-441.
-
(1995)
Nature
, vol.373
, pp. 438-441
-
-
Dhein, J.1
Walczak, H.2
Baumler, C.3
Debatin, K.M.4
Krammer, P.H.5
-
29
-
-
84864318803
-
A death effector domain chain DISC model reveals a crucial role for Caspase-8 chain assembly in mediating apoptotic cell death
-
Dickens L.S., Boyd RS, Jukes-Jones R, Hughes MA, Robinson GL, Fairall L, Schwabe JW, Cain K, Macfarlane M. 2012. A death effector domain chain DISC model reveals a crucial role for Caspase-8 chain assembly in mediating apoptotic cell death. Mol Cell 47: 291-305.
-
(2012)
Mol Cell
, vol.47
, pp. 291-305
-
-
Dickens, L.S.1
Boyd, R.S.2
Jukes-Jones, R.3
Hughes, M.A.4
Robinson, G.L.5
Fairall, L.6
Schwabe, J.W.7
Cain, K.8
McFarlane, M.9
-
30
-
-
84861712290
-
Survival function of the FADD-CASPASE-8-cFLIP(L) complex
-
Dillon C.P., Oberst A, Weinlich R, Janke LJ, Kang TB, Ben-Moshe T., Mak TW, Wallach D, Green DR. 2012. Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep 1: 401-407.
-
(2012)
Cell Rep
, vol.1
, pp. 401-407
-
-
Dillon, C.P.1
Oberst, A.2
Weinlich, R.3
Janke, L.J.4
Kang, T.B.5
Ben-Moshe, T.6
Mak, T.W.7
Wallach, D.8
Green, D.R.9
-
31
-
-
0029881627
-
Different susceptibility of cytotoxic T cells to CD95 (Fas/Apo-1) ligand-mediated cell death after activation in vitro versus in vivo
-
Ehl S., Hoffmann-Rohrer U, Nagata S, Hengartner H, Zinkernagel R. 1996. Different susceptibility of cytotoxic T cells to CD95 (Fas/Apo-1) ligand-mediated cell death after activation in vitro versus in vivo. J Immunol 156: 2357-2360.
-
(1996)
J Immunol
, vol.156
, pp. 2357-2360
-
-
Ehl, S.1
Hoffmann-Rohrer, U.2
Nagata, S.3
Hengartner, H.4
Zinkernagel, R.5
-
32
-
-
0038339094
-
TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kB
-
Ehrhardt H., Fulda S, Schmid I, Hiscott J, Debatin KM, Jeremias I. 2003. TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kB. Oncogene 22: 3842-3852.
-
(2003)
Oncogene
, vol.22
, pp. 3842-3852
-
-
Ehrhardt, H.1
Fulda, S.2
Schmid, I.3
Hiscott, J.4
Debatin, K.M.5
Jeremias, I.6
-
33
-
-
0031038463
-
Fas signal transduction triggers either proliferation or apoptosis in human fibroblasts
-
Freiberg R.A., Spencer DM, Choate KA, Duh HJ, Schreiber SL, Crabtree GR, Khavari PA. 1997. Fas signal transduction triggers either proliferation or apoptosis in human fibroblasts. J Invest Dermatol 108: 215-219.
-
(1997)
J Invest Dermatol
, vol.108
, pp. 215-219
-
-
Freiberg, R.A.1
Spencer, D.M.2
Choate, K.A.3
Duh, H.J.4
Schreiber, S.L.5
Crabtree, G.R.6
Khavari, P.A.7
-
34
-
-
0028783367
-
Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage
-
Galle P.R., Hofmann WJ, Walczak H, Schaller H, Otto G, Stremmel W, Krammer PH, Runkel L. 1995. Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage. J Exp Med 182: 1223-1230.
-
(1995)
J Exp Med
, vol.182
, pp. 1223-1230
-
-
Galle, P.R.1
Hofmann, W.J.2
Walczak, H.3
Schaller, H.4
Otto, G.5
Stremmel, W.6
Krammer, P.H.7
Runkel, L.8
-
35
-
-
24144489702
-
Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL
-
Ganten T.M., Koschny R, Haas TL, Sykora J, Li-Weber M, Herzer K., Walczak H. 2005. Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL. Hepatology 42: 588-597.
-
(2005)
Hepatology
, vol.42
, pp. 588-597
-
-
Ganten, T.M.1
Koschny, R.2
Haas, T.L.3
Sykora, J.4
Li-Weber, M.5
Herzer, K.6
Walczak, H.7
-
36
-
-
33646393778
-
Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs
-
Ganten T.M., Koschny R, Sykora J, Schulze-Bergkamen H, Buchler P., Haas TL, Schader MB, Untergasser A, Stremmel W, Walczak H. 2006. Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs. Clin Cancer Res 12: 2640-2646.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2640-2646
-
-
Ganten, T.M.1
Koschny, R.2
Sykora, J.3
Schulze-Bergkamen, H.4
Buchler, P.5
Haas, T.L.6
Schader, M.B.7
Untergasser, A.8
Stremmel, W.9
Walczak, H.10
-
37
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
Gerlach B., Cordier SM, Schmukle AC, Emmerich CH, Rieser E., Haas TL, Webb AI, Rickard JA, Anderton H, Wong W.W., et al. 2011. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 471: 591-596.
-
(2011)
Nature
, vol.471
, pp. 591-596
-
-
Gerlach, B.1
Cordier, S.M.2
Schmukle, A.C.3
Emmerich, C.H.4
Rieser, E.5
Haas, T.L.6
Webb, A.I.7
Rickard, J.A.8
Anderton, H.9
Wong, W.W.10
-
38
-
-
77952991726
-
Cancer: A wolf in wolf 's clothing
-
Green DR. 2010. Cancer: A wolf in wolf 's clothing. Nature 465: 433.
-
(2010)
Nature
, vol.465
, pp. 433
-
-
Green, D.R.1
-
39
-
-
84877157335
-
Mitos, MOMP, and death
-
doi: 10.1101/cshperspect.a008706
-
Green DR. 2013. Mitos, MOMP, and death. Cold Spring Harb Perspect Biol doi: 10.1101/cshperspect.a008706.
-
(2013)
Cold Spring Harb Perspect Biol
-
-
Green, D.R.1
-
40
-
-
0033534446
-
Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death
-
Gross A., Yin XM, Wang K, Wei MC, Jockel J, Milliman C, Erdjument-Bromage H, Tempst P, Korsmeyer SJ. 1999. Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J Biol Chem 274: 1156-1163.
-
(1999)
J Biol Chem
, vol.274
, pp. 1156-1163
-
-
Gross, A.1
Yin, X.M.2
Wang, K.3
Wei, M.C.4
Jockel, J.5
Milliman, C.6
Erdjument-Bromage, H.7
Tempst, P.8
Korsmeyer, S.J.9
-
41
-
-
80052845560
-
Caspase-8 regulates TNF-a-induced epithelial necroptosis and terminal ileitis
-
Gunther C., Martini E, Wittkopf N, Amann K, Weigmann B, Neumann H, Waldner MJ, Hedrick SM, Tenzer S, Neurath M.F., et al. 2012. Caspase-8 regulates TNF-a-induced epithelial necroptosis and terminal ileitis. Nature 477: 335-339.
-
(2012)
Nature
, vol.477
, pp. 335-339
-
-
Gunther, C.1
Martini, E.2
Wittkopf, N.3
Amann, K.4
Weigmann, B.5
Neumann, H.6
Waldner, M.J.7
Hedrick, S.M.8
Tenzer, S.9
Neurath, M.F.10
-
43
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-a
-
He S., Wang L, Miao L, Wang T, Du F, Zhao L, Wang X. 2009. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-a. Cell 137: 1100-1111.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
Wang, X.7
-
44
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi J., Christofferson DE, Ng A, Yao J, Degterev A, Xavier R.J., Yuan J. 2008. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 135: 1311-1323.
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
Yuan, J.7
-
45
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler N., Zaru R, Micheau O, Thome M, Attinger A, Valitutti S., Bodmer JL, Schneider P, Seed B, Tschopp J. 2000. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 1: 489-495.
-
(2000)
Nat Immunol
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
Thome, M.4
Attinger, A.5
Valitutti, S.6
Bodmer, J.L.7
Schneider, P.8
Seed, B.9
Tschopp, J.10
-
46
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler M., Thome M, Hahne M, Schneider P, Hofmann K, Steiner V., Bodmer JL, Schroter M, Burns K, Mattmann C, et al. 1997. Inhibition of death receptor signals by cellular FLIP. Nature 388: 190-195.
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
Bodmer, J.L.7
Schroter, M.8
Burns, K.9
Mattmann, C.10
-
47
-
-
0027281373
-
A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen
-
Itoh N., Nagata S. 1993. A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen. J Biol Chem 268: 10932-10937.
-
(1993)
J Biol Chem
, vol.268
, pp. 10932-10937
-
-
Itoh, N.1
Nagata, S.2
-
48
-
-
0025916387
-
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
-
Itoh N., Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M., Hase A, Seto Y, Nagata S. 1991. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66: 233-243.
-
(1991)
Cell
, vol.66
, pp. 233-243
-
-
Itoh, N.1
Yonehara, S.2
Ishii, A.3
Yonehara, M.4
Mizushima, S.5
Sameshima, M.6
Hase, A.7
Seto, Y.8
Nagata, S.9
-
49
-
-
0034702911
-
Involvement of CD95/Apo1/Fas in cell death after myocardial ischemia
-
Jeremias I., Kupatt C, Martin-Villalba A, Habazettl H, Schenkel J., Boekstegers P, Debatin KM. 2000. Involvement of CD95/Apo1/Fas in cell death after myocardial ischemia. Circulation 102: 915-920.
-
(2000)
Circulation
, vol.102
, pp. 915-920
-
-
Jeremias, I.1
Kupatt, C.2
Martin-Villalba, A.3
Habazettl, H.4
Schenkel, J.5
Boekstegers, P.6
Debatin, K.M.7
-
50
-
-
69249208481
-
XIAP discriminates between type I and type II FAS-induced apoptosis
-
Jost P.J., Grabow S, Gray D, McKenzie MD, Nachbur U, Huang D.C., Bouillet P, Thomas HE, Borner C, Silke J, et al. 2009. XIAP discriminates between type I and type II FAS-induced apoptosis. Nature 460: 1035-1039.
-
(2009)
Nature
, vol.460
, pp. 1035-1039
-
-
Jost, P.J.1
Grabow, S.2
Gray, D.3
McKenzie, M.D.4
Nachbur, U.5
Huang, D.C.6
Bouillet, P.7
Thomas, H.E.8
Borner, C.9
Silke, J.10
-
51
-
-
0028893078
-
Fas(CD95)/ FasL interactions required for programmed cell death after T-cell activation
-
Ju S.T., Panka DJ, Cui H, Ettinger R, el-Khatib M, Sherr DH, Stanger B.Z., Marshak-Rothstein A. 1995. Fas(CD95)/ FasL interactions required for programmed cell death after T-cell activation. Nature 373: 444-448.
-
(1995)
Nature
, vol.373
, pp. 444-448
-
-
Ju, S.T.1
Panka, D.J.2
Cui, H.3
Ettinger, R.4
el-Khatib, M.5
Sherr, D.H.6
Stanger, B.Z.7
Marshak-Rothstein, A.8
-
52
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser W.J., Upton JW, Long AB, Livingston-Rosanoff D, Daley-Bauer L.P., Hakem R, Caspary T, Mocarski ES. 2011. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471: 368-372.
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
Caspary, T.7
Mocarski, E.S.8
-
53
-
-
79955761920
-
Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95-and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex
-
Kavuri S.M., Geserick P, Berg D, Dimitrova DP, Feoktistova M, Siegmund D., Gollnick H, Neumann M, Wajant H, Leverkus M. 2011. Cellular FLICE-inhibitory protein (cFLIP) isoforms block CD95-and TRAIL death receptor-induced gene induction irrespective of processing of caspase-8 or cFLIP in the death-inducing signaling complex. J Biol Chem 286: 16631-16646.
-
(2011)
J Biol Chem
, vol.286
, pp. 16631-16646
-
-
Kavuri, S.M.1
Geserick, P.2
Berg, D.3
Dimitrova, D.P.4
Feoktistova, M.5
Siegmund, D.6
Gollnick, H.7
Neumann, M.8
Wajant, H.9
Leverkus, M.10
-
54
-
-
0033386808
-
Caspase activation is required for T cell proliferation
-
Kennedy N.J., Kataoka T, Tschopp J, Budd RC. 1999. Caspase activation is required for T cell proliferation. J Exp Med 190: 1891-1896.
-
(1999)
J Exp Med
, vol.190
, pp. 1891-1896
-
-
Kennedy, N.J.1
Kataoka, T.2
Tschopp, J.3
Budd, R.C.4
-
55
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
-
Kischkel F.C., Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer PH, Peter ME. 1995. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J 14: 5579-5588.
-
(1995)
EMBO J
, vol.14
, pp. 5579-5588
-
-
Kischkel, F.C.1
Hellbardt, S.2
Behrmann, I.3
Germer, M.4
Pawlita, M.5
Krammer, P.H.6
Peter, M.E.7
-
56
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADDand caspase-8 to death receptors 4 and 5
-
Kischkel F.C., Lawrence DA, Chuntharapai A, Schow P, Kim K.J., Ashkenazi A. 2000. Apo2L/TRAIL-dependent recruitment of endogenous FADDand caspase-8 to death receptors 4 and 5. Immunity 12: 611-620.
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
57
-
-
0035824635
-
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8
-
Kischkel F.C., Lawrence DA, Tinel A, LeBlanc H, Virmani A, Schow P., Gazdar A, Blenis J, Arnott D, Ashkenazi A. 2001. Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. J Biol Chem 276: 46639-46646.
-
(2001)
J Biol Chem
, vol.276
, pp. 46639-46646
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Tinel, A.3
LeBlanc, H.4
Virmani, A.5
Schow, P.6
Gazdar, A.7
Blenis, J.8
Arnott, D.9
Ashkenazi, A.10
-
58
-
-
0029969717
-
A death-domain-containing receptor that mediates apoptosis
-
Kitson J., Raven T, Jiang YP, Goeddel DV, Giles KM, Pun KT, Grinham C.J., Brown R, Farrow SN. 1996. A death-domain-containing receptor that mediates apoptosis. Nature 384: 372-375.
-
(1996)
Nature
, vol.384
, pp. 372-375
-
-
Kitson, J.1
Raven, T.2
Jiang, Y.P.3
Goeddel, D.V.4
Giles, K.M.5
Pun, K.T.6
Grinham, C.J.7
Brown, R.8
Farrow, S.N.9
-
59
-
-
40149099894
-
Yes and PI3K bind CD95 to signal invasion of glioblastoma
-
Kleber S., Sancho-Martinez I, Wiestler B, Beisel A, Gieffers C, Hill O., Thiemann M, Mueller W, Sykora J, Kuhn A, et al. 2008. Yes and PI3K bind CD95 to signal invasion of glioblastoma. Cancer Cell 13: 235-248.
-
(2008)
Cancer Cell
, vol.13
, pp. 235-248
-
-
Kleber, S.1
Sancho-Martinez, I.2
Wiestler, B.3
Beisel, A.4
Gieffers, C.5
Hill, O.6
Thiemann, M.7
Mueller, W.8
Sykora, J.9
Kuhn, A.10
-
60
-
-
68049084674
-
Breaking the chains: Structure and function of the deubiquitinases
-
Komander D., Clague MJ, Urbe S. 2009a. Breaking the chains: Structure and function of the deubiquitinases. Nat Rev Mol Cell Biol 10: 550-563.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
61
-
-
67349231313
-
Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
-
Komander D., Reyes-Turcu F, Licchesi JD, Odenwaelder P, Wilkinson K.D., Barford D. 2009b. Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains. EMBO Rep 10: 466-473.
-
(2009)
EMBO Rep
, vol.10
, pp. 466-473
-
-
Komander, D.1
Reyes-Turcu, F.2
Licchesi, J.D.3
Odenwaelder, P.4
Wilkinson, K.D.5
Barford, D.6
-
62
-
-
0031002790
-
Essential roles of the Fas ligand in the development of hepatitis
-
Kondo T., Suda T, Fukuyama H, Adachi M, Nagata S. 1997. Essential roles of the Fas ligand in the development of hepatitis. Nat Med 3: 409-413.
-
(1997)
Nat Med
, vol.3
, pp. 409-413
-
-
Kondo, T.1
Suda, T.2
Fukuyama, H.3
Adachi, M.4
Nagata, S.5
-
63
-
-
33947368690
-
TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window
-
Koschny R., Ganten TM, Sykora J, Haas TL, Sprick MR, Kolb A., Stremmel W, Walczak H. 2007. TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window. Hepatology 45: 649-658.
-
(2007)
Hepatology
, vol.45
, pp. 649-658
-
-
Koschny, R.1
Ganten, T.M.2
Sykora, J.3
Haas, T.L.4
Sprick, M.R.5
Kolb, A.6
Stremmel, W.7
Walczak, H.8
-
64
-
-
70350484946
-
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
-
Kovalenko A., Kim JC, Kang TB, Rajput A, Bogdanov K, Dittrich-Breiholz O, Kracht M, Brenner O, Wallach D. 2009. Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J Exp Med 206: 2161-2177.
-
(2009)
J Exp Med
, vol.206
, pp. 2161-2177
-
-
Kovalenko, A.1
Kim, J.C.2
Kang, T.B.3
Rajput, A.4
Bogdanov, K.5
Dittrich-Breiholz, O.6
Kracht, M.7
Brenner, O.8
Wallach, D.9
-
65
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
-
Lawrence D., Shahrokh Z, Marsters S, Achilles K, Shih D, Mounho B., Hillan K, Totpal K, DeForge L, Schow P, et al. 2001. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat Med 7: 383-385.
-
(2001)
Nat Med
, vol.7
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
Achilles, K.4
Shih, D.5
Mounho, B.6
Hillan, K.7
Totpal, K.8
DeForge, L.9
Schow, P.10
-
66
-
-
0037304773
-
Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo
-
Lee P., Sata M, Lefer DJ, Factor SM, Walsh K, Kitsis RN. 2003. Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo. Am J Physiol Heart Circ Physiol 284: H456-H463.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
-
-
Lee, P.1
Sata, M.2
Lefer, D.J.3
Factor, S.M.4
Walsh, K.5
Kitsis, R.N.6
-
67
-
-
77954541163
-
TRAIL signaling is mediated by DR4 in pancreatic tumor cells despite the expression of functional DR5
-
Lemke J., Noack A, Adam D, Tchikov V, Bertsch U, Roder C, Schutze S., Wajant H, Kalthoff H, Trauzold A. 2010. TRAIL signaling is mediated by DR4 in pancreatic tumor cells despite the expression of functional DR5. J MolMed (Berl) 88: 729-740.
-
(2010)
J MolMed (Berl)
, vol.88
, pp. 729-740
-
-
Lemke, J.1
Noack, A.2
Adam, D.3
Tchikov, V.4
Bertsch, U.5
Roder, C.6
Schutze, S.7
Wajant, H.8
Kalthoff, H.9
Trauzold, A.10
-
68
-
-
61649103747
-
Structural basis for recognition of diubiquitins by NEMO
-
Lo Y.C., Lin SC, Rospigliosi CC, Conze DB, Wu CJ, Ashwell J.D., Eliezer D, Wu H. 2009. Structural basis for recognition of diubiquitins by NEMO. Mol Cell 33: 602-615.
-
(2009)
Mol Cell
, vol.33
, pp. 602-615
-
-
Lo, Y.C.1
Lin, S.C.2
Rospigliosi, C.C.3
Conze, D.B.4
Wu, C.J.5
Ashwell, J.D.6
Eliezer, D.7
Wu, H.8
-
69
-
-
0025269050
-
Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor
-
Loetscher H., Pan YC, Lahm HW, Gentz R, Brockhaus M, Tabuchi H., Lesslauer W. 1990. Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor. Cell 61: 351-359.
-
(1990)
Cell
, vol.61
, pp. 351-359
-
-
Loetscher, H.1
Pan, Y.C.2
Lahm, H.W.3
Gentz, R.4
Brockhaus, M.5
Tabuchi, H.6
Lesslauer, W.7
-
70
-
-
0027946007
-
A null mutation in the perforin gene impairs cytolytic T lymphocyte-and natural killer cell-mediated cytotoxicity
-
Lowin B., Beermann F, Schmidt A, Tschopp J. 1994a. A null mutation in the perforin gene impairs cytolytic T lymphocyte-and natural killer cell-mediated cytotoxicity. Proc Natl Acad Sci 91: 11571-11575.
-
(1994)
Proc Natl Acad Sci
, vol.91
, pp. 11571-11575
-
-
Lowin, B.1
Beermann, F.2
Schmidt, A.3
Tschopp, J.4
-
71
-
-
0027937745
-
Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways
-
Lowin B., Hahne M, Mattmann C, Tschopp J. 1994b. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 370: 650-652.
-
(1994)
Nature
, vol.370
, pp. 650-652
-
-
Lowin, B.1
Hahne, M.2
Mattmann, C.3
Tschopp, J.4
-
72
-
-
0030155964
-
Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA
-
Marsters S.A., Pitti RM, Donahue CJ, Ruppert S, Bauer KD, Ashkenazi A. 1996. Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA. Curr Biol 6: 750-752.
-
(1996)
Curr Biol
, vol.6
, pp. 750-752
-
-
Marsters, S.A.1
Pitti, R.M.2
Donahue, C.J.3
Ruppert, S.4
Bauer, K.D.5
Ashkenazi, A.6
-
73
-
-
0033562658
-
CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons
-
Martin-Villalba A, Herr I, Jeremias I, Hahne M, Brandt R, Vogel J., Schenkel J, Herdegen T, Debatin KM. 1999. CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons. J Neurosci 19: 3809-3817.
-
(1999)
J Neurosci
, vol.19
, pp. 3809-3817
-
-
Martin-Villalba, A.1
Herr, I.2
Jeremias, I.3
Hahne, M.4
Brandt, R.5
Vogel, J.6
Schenkel, J.7
Herdegen, T.8
Debatin, K.M.9
-
74
-
-
0041853690
-
Induction of TNF receptor Imediated apoptosis via two sequential signaling complexes
-
Micheau O., Tschopp J. 2003. Induction of TNF receptor Imediated apoptosis via two sequential signaling complexes. Cell 114: 181-190.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
75
-
-
18344385475
-
TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator
-
Migone T.S., Zhang J, Luo X, Zhuang L, Chen C, Hu B, Hong J.S., Perry JW, Chen SF, Zhou JX, et al. 2002. TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. Immunity 16: 479-492.
-
(2002)
Immunity
, vol.16
, pp. 479-492
-
-
Migone, T.S.1
Zhang, J.2
Luo, X.3
Zhuang, L.4
Chen, C.5
Hu, B.6
Hong, J.S.7
Perry, J.W.8
Chen, S.F.9
Zhou, J.X.10
-
76
-
-
0033061656
-
Therapeutic effect of an anti-Fas ligand mAb on lethal graft-versus-host disease
-
Miwa K., Hashimoto H, Yatomi T, Nakamura N, Nagata S, Suda T. 1999. Therapeutic effect of an anti-Fas ligand mAb on lethal graft-versus-host disease. Int Immunol 11: 925-931.
-
(1999)
Int Immunol
, vol.11
, pp. 925-931
-
-
Miwa, K.1
Hashimoto, H.2
Yatomi, T.3
Nakamura, N.4
Nagata, S.5
Suda, T.6
-
77
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/ APO-1) death-inducing signaling complex
-
Muzio M., Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A., Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R., et al. 1996. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/ APO-1) death-inducing signaling complex. Cell 85: 817-827.
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
-
78
-
-
0000392840
-
The treatment of malignant tumors by bacterial toxins as developed by the late William B. Coley, M.D., reviewed in the light of modern research
-
Nauts H.C., Swift WE, Coley BL. 1946. The treatment of malignant tumors by bacterial toxins as developed by the late William B. Coley, M.D., reviewed in the light of modern research. Cancer Res 6: 205-216.
-
(1946)
Cancer Res
, vol.6
, pp. 205-216
-
-
Nauts, H.C.1
Swift, W.E.2
Coley, B.L.3
-
79
-
-
77049151988
-
A review of the influence of bacterial infection and of bacterial products (Coley's toxins) on malignant tumors in man; a critical analysis of 30 inoperable cases treated by Coley's mixed toxins, in which diagnosis was confirmed by microscopic examination selected for special study
-
Nauts H.C., Fowler GA, Bogatko FH. 1953. A review of the influence of bacterial infection and of bacterial products (Coley's toxins) on malignant tumors in man; a critical analysis of 30 inoperable cases treated by Coley's mixed toxins, in which diagnosis was confirmed by microscopic examination selected for special study. Acta Med Scand Suppl 276: 1-103.
-
(1953)
Acta Med Scand Suppl
, vol.276
, pp. 1-103
-
-
Nauts, H.C.1
Fowler, G.A.2
Bogatko, F.H.3
-
81
-
-
60549089207
-
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
-
Nikolaev A., McLaughlin T, O'Leary DD, Tessier-Lavigne M. 2009. APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature 457: 981-989.
-
(2009)
Nature
, vol.457
, pp. 981-989
-
-
Nikolaev, A.1
McLaughlin, T.2
O'Leary, D.D.3
Tessier-Lavigne, M.4
-
82
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst A., Dillon CP, Weinlich R, McCormick LL, Fitzgerald P, Pop C, Hakem R, Salvesen GS, Green DR. 2011. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 471: 363-367.
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
Hakem, R.7
Salvesen, G.S.8
Green, D.R.9
-
83
-
-
0026706261
-
Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/ nerve growth factor receptor superfamily. Sequence identity with the Fas antigen
-
Oehm A., Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Li-Weber M, Richards S, Dhein J, Trauth BC, et al. 1992. Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/ nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. J Biol Chem 267: 10709-10715.
-
(1992)
J Biol Chem
, vol.267
, pp. 10709-10715
-
-
Oehm, A.1
Behrmann, I.2
Falk, W.3
Pawlita, M.4
Maier, G.5
Klas, C.6
Li-Weber, M.7
Richards, S.8
Dhein, J.9
Trauth, B.C.10
-
84
-
-
0027291205
-
Lethal effect of the anti-Fas antibody inmice
-
Ogasawara J., Watanabe-Fukunaga R, Adachi M, Matsuzawa A, Kasugai T, Kitamura Y, Itoh N, Suda T, Nagata S. 1993. Lethal effect of the anti-Fas antibody inmice. Nature 364: 806-809.
-
(1993)
Nature
, vol.364
, pp. 806-809
-
-
Ogasawara, J.1
Watanabe-Fukunaga, R.2
Adachi, M.3
Matsuzawa, A.4
Kasugai, T.5
Kitamura, Y.6
Itoh, N.7
Suda, T.8
Nagata, S.9
-
85
-
-
0027444939
-
Fas/APO-1 expression and function on malignant cells of hematologic and nonhematologic origin
-
Owen-Schaub LB, Meterissian S, Ford RJ. 1993. Fas/APO-1 expression and function on malignant cells of hematologic and nonhematologic origin. J Immunother Emphasis Tumor Immunol 14: 234-241.
-
(1993)
J Immunother Emphasis Tumor Immunol
, vol.14
, pp. 234-241
-
-
Owen-Schaub, L.B.1
Meterissian, S.2
Ford, R.J.3
-
86
-
-
0031453821
-
Studies on the mechanism of dimethylnitrosamine-induced acute liver injury in mice
-
Oyaizu T., Shikata N, Senzaki H, Matsuzawa A, Tsubura A. 1997. Studies on the mechanism of dimethylnitrosamine-induced acute liver injury in mice. Exp Toxicol Pathol 49: 375-380.
-
(1997)
Exp Toxicol Pathol
, vol.49
, pp. 375-380
-
-
Oyaizu, T.1
Shikata, N.2
Senzaki, H.3
Matsuzawa, A.4
Tsubura, A.5
-
87
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
-
Pan G., Ni J, Wei YF, Yu G, Gentz R, Dixit VM. 1997a. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 277: 815-818.
-
(1997)
Science
, vol.277
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.F.3
Yu, G.4
Gentz, R.5
Dixit, V.M.6
-
88
-
-
0030996297
-
The receptor for the cytotoxic ligand TRAIL
-
Pan G., O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM. 1997b. The receptor for the cytotoxic ligand TRAIL. Science 276: 111-113.
-
(1997)
Science
, vol.276
, pp. 111-113
-
-
Pan, G.1
O'Rourke, K.2
Chinnaiyan, A.M.3
Gentz, R.4
Ebner, R.5
Ni, J.6
Dixit, V.M.7
-
89
-
-
0032563275
-
Identification and functional characterization of DR6, a novel death domain-containing TNF receptor
-
Pan G., Bauer JH, Haridas V, Wang S, Liu D, Yu G, Vincenz C, Aggarwal B.B., Ni J, Dixit VM. 1998. Identification and functional characterization of DR6, a novel death domain-containing TNF receptor. FEBS Lett 431: 351-356.
-
(1998)
FEBS Lett
, vol.431
, pp. 351-356
-
-
Pan, G.1
Bauer, J.H.2
Haridas, V.3
Wang, S.4
Liu, D.5
Yu, G.6
Vincenz, C.7
Aggarwal, B.B.8
Ni, J.9
Dixit, V.M.10
-
90
-
-
84877102240
-
Cellular mechanisms controlling caspase activation and function
-
doi: 10.1101/cshperspect. a008672
-
Parrish A.B., Freel CD, Kornbluth S. 2013. Cellular mechanisms controlling caspase activation and function. Cold Spring Harb Perspect Biol doi: 10.1101/cshperspect. a008672.
-
(2013)
Cold Spring Harb Perspect Biol
-
-
Parrish, A.B.1
Freel, C.D.2
Kornbluth, S.3
-
91
-
-
0031754828
-
Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis
-
Peter M.E., Krammer PH. 1998. Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis. Curr Opin Immunol 10: 545-551.
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 545-551
-
-
Peter, M.E.1
Krammer, P.H.2
-
92
-
-
34247536682
-
The CD95 receptor: Apoptosis revisited
-
Peter M.E., Budd RC, Desbarats J, Hedrick SM, Hueber AO, Newell M.K., Owen LB, Pope RM, Tschopp J, Wajant H, et al. 2007. The CD95 receptor: Apoptosis revisited. Cell 129: 447-450.
-
(2007)
Cell
, vol.129
, pp. 447-450
-
-
Peter, M.E.1
Budd, R.C.2
Desbarats, J.3
Hedrick, S.M.4
Hueber, A.O.5
Newell, M.K.6
Owen, L.B.7
Pope, R.M.8
Tschopp, J.9
Wajant, H.10
-
93
-
-
17544367410
-
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
-
Pitti R.M., Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. 1996. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 271: 12687-12690.
-
(1996)
J Biol Chem
, vol.271
, pp. 12687-12690
-
-
Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
-
94
-
-
69249100500
-
Human caspases: Activation, specificity, and regulation
-
Pop C., Salvesen GS. 2009. Human caspases: Activation, specificity, and regulation. J Biol Chem 284: 21777-21781.
-
(2009)
J Biol Chem
, vol.284
, pp. 21777-21781
-
-
Pop, C.1
Salvesen, G.S.2
-
95
-
-
62549155321
-
Specific recognition of linear ubiquitin chains by NEMO is important for NF-kB activation
-
Rahighi S., Ikeda F, Kawasaki M, Akutsu M, Suzuki N, Kato R., Kensche T, Uejima T, Bloor S, Komander D, et al. 2009. Specific recognition of linear ubiquitin chains by NEMO is important for NF-kB activation. Cell 136: 1098-1109.
-
(2009)
Cell
, vol.136
, pp. 1098-1109
-
-
Rahighi, S.1
Ikeda, F.2
Kawasaki, M.3
Akutsu, M.4
Suzuki, N.5
Kato, R.6
Kensche, T.7
Uejima, T.8
Bloor, S.9
Komander, D.10
-
96
-
-
0027531439
-
Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice
-
Reap E.A., Sobel ES, Cohen PL, Eisenberg RA. 1993. Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice. J Exp Med 177: 69-78.
-
(1993)
J Exp Med
, vol.177
, pp. 69-78
-
-
Reap, E.A.1
Sobel, E.S.2
Cohen, P.L.3
Eisenberg, R.A.4
-
97
-
-
84890549960
-
Linear ubiquitination: A newly discovered regulator of cell signalling
-
Rieser E., Schmukle AC, Walczak H. 2012. Linear ubiquitination: A newly discovered regulator of cell signalling. Trends Biochem Sci 24: 229-231.
-
(2012)
Trends Biochem Sci
, vol.24
, pp. 229-231
-
-
Rieser, E.1
Schmukle, A.C.2
Walczak, H.3
-
98
-
-
79955481608
-
Impact of death receptor signaling on the malignancy of pancreatic ductal adenocarcinoma
-
Roder C., Trauzold A, Kalthoff H. 2011. Impact of death receptor signaling on the malignancy of pancreatic ductal adenocarcinoma. Eur J Cell Biol 90: 450-455.
-
(2011)
Eur J Cell Biol
, vol.90
, pp. 450-455
-
-
Roder, C.1
Trauzold, A.2
Kalthoff, H.3
-
99
-
-
0021350056
-
A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice
-
Roths J.B., Murphy ED, Eicher EM. 1984. A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice. J Exp Med 159: 1-20.
-
(1984)
J Exp Med
, vol.159
, pp. 1-20
-
-
Roths, J.B.1
Murphy, E.D.2
Eicher, E.M.3
-
101
-
-
65349168340
-
Tyrosine phosphorylation and CD95: A FAScinating switch
-
Sancho-Martinez I, Martin-Villalba A. 2009. Tyrosine phosphorylation and CD95: A FAScinating switch. Cell Cycle 8: 838-842.
-
(2009)
Cell Cycle
, vol.8
, pp. 838-842
-
-
Sancho-Martinez, I.1
Martin-Villalba, A.2
-
102
-
-
0025711127
-
Molecular cloning and expression of a receptor for human tumor necrosis factor
-
Schall T.J., Lewis M, Koller KJ, Lee A, Rice GC, Wong GH, Gatanaga T., Granger GA, Lentz R, Raab H, et al. 1990. Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell 61: 361-370.
-
(1990)
Cell
, vol.61
, pp. 361-370
-
-
Schall, T.J.1
Lewis, M.2
Koller, K.J.3
Lee, A.4
Rice, G.C.5
Wong, G.H.6
Gatanaga, T.7
Granger, G.A.8
Lentz, R.9
Raab, H.10
-
103
-
-
84864294821
-
Stoichiometry of the CD95 death-inducing signaling complex: Experimental and modeling evidence for a death effector domain chain model
-
Schleich K., Warnken U, Fricker N, Ozturk S, Richter P, Kammerer K., Schnolzer M, Krammer PH, Lavrik IN. 2012. Stoichiometry of the CD95 death-inducing signaling complex: Experimental and modeling evidence for a death effector domain chain model. Mol Cell 47: 306-319.
-
(2012)
Mol Cell
, vol.47
, pp. 306-319
-
-
Schleich, K.1
Warnken, U.2
Fricker, N.3
Ozturk, S.4
Richter, P.5
Kammerer, K.6
Schnolzer, M.7
Krammer, P.H.8
Lavrik, I.N.9
-
104
-
-
0031239984
-
TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL
-
Screaton G.R., Mongkolsapaya J, Xu XN, Cowper AE, McMichael AJ, Bell JI. 1997a. TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL. Curr Biol 7: 693-696.
-
(1997)
Curr Biol
, vol.7
, pp. 693-696
-
-
Screaton, G.R.1
Mongkolsapaya, J.2
Xu, X.N.3
Cowper, A.E.4
McMichael, A.J.5
Bell, J.I.6
-
105
-
-
0030940538
-
LARD: A new lymphoidspecific death domain containing receptor regulated by alternative pre-mRNA splicing
-
Screaton G.R., Xu XN, Olsen AL, Cowper AE, Tan R, McMichael AJ, Bell JI. 1997b. LARD: A new lymphoidspecific death domain containing receptor regulated by alternative pre-mRNA splicing. Proc Natl Acad Sci 94: 4615-4619.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 4615-4619
-
-
Screaton, G.R.1
Xu, X.N.2
Olsen, A.L.3
Cowper, A.E.4
Tan, R.5
McMichael, A.J.6
Bell, J.I.7
-
106
-
-
84959795393
-
Achemical treatment of tumors. IX. Reactions of micewith primary subcutaneous tumors to injection of a hemorrhage-producing bacterial polysaccharide
-
Shear M.J., Perrault A. 1944. Achemical treatment of tumors. IX. Reactions of micewith primary subcutaneous tumors to injection of a hemorrhage-producing bacterial polysaccharide. J Natl Cancer Inst 44: 461-476.
-
(1944)
J Natl Cancer Inst
, vol.44
, pp. 461-476
-
-
Shear, M.J.1
Perrault, A.2
-
107
-
-
0030792712
-
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
-
Sheridan J.P., Marsters SA, Pitti RM, Gurney A, Skubatch M, Baldwin D., Ramakrishnan L, Gray CL, Baker K, Wood W.I., et al. 1997. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 277: 818-821.
-
(1997)
Science
, vol.277
, pp. 818-821
-
-
Sheridan, J.P.1
Marsters, S.A.2
Pitti, R.M.3
Gurney, A.4
Skubatch, M.5
Baldwin, D.6
Ramakrishnan, L.7
Gray, C.L.8
Baker, K.9
Wood, W.I.10
-
108
-
-
0031005576
-
Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
-
Simonet W.S., Lacey DL, Dunstan CR, Kelley M, Chang MS, Luthy R., Nguyen HQ, Wooden S, Bennett L, Boone T, et al. 1997. Osteoprotegerin: A novel secreted protein involved in the regulation of bone density. Cell 89: 309-319.
-
(1997)
Cell
, vol.89
, pp. 309-319
-
-
Simonet, W.S.1
Lacey, D.L.2
Dunstan, C.R.3
Kelley, M.4
Chang, M.S.5
Luthy, R.6
Nguyen, H.Q.7
Wooden, S.8
Bennett, L.9
Boone, T.10
-
109
-
-
0025313006
-
A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins
-
Smith C.A., Davis T, Anderson D, Solam L, Beckmann MP, Jerzy R., Dower SK, Cosman D, Goodwin RG. 1990. A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science 248: 1019-1023.
-
(1990)
Science
, vol.248
, pp. 1019-1023
-
-
Smith, C.A.1
Davis, T.2
Anderson, D.3
Solam, L.4
Beckmann, M.P.5
Jerzy, R.6
Dower, S.K.7
Cosman, D.8
Goodwin, R.G.9
-
110
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
Sprick M.R., Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, Krammer P.H., Walczak H. 2000. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12: 599-609.
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
Weigand, M.A.2
Rieser, E.3
Rauch, C.T.4
Juo, P.5
Blenis, J.6
Krammer, P.H.7
Walczak, H.8
-
111
-
-
0037009370
-
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8
-
Sprick M.R., Rieser E, Stahl H, Grosse-Wilde A, Weigand MA, Walczak H. 2002. Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8. EMBO J 21: 4520-4530.
-
(2002)
EMBO J
, vol.21
, pp. 4520-4530
-
-
Sprick, M.R.1
Rieser, E.2
Stahl, H.3
Grosse-Wilde, A.4
Weigand, M.A.5
Walczak, H.6
-
112
-
-
17344387813
-
Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis
-
Strand S., Hofmann WJ, Grambihler A, Hug H, Volkmann M, Otto G, Wesch H, Mariani SM, Hack V, Stremmel W., et al. 1998. Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis. Nat Med 4: 588-593.
-
(1998)
Nat Med
, vol.4
, pp. 588-593
-
-
Strand, S.1
Hofmann, W.J.2
Grambihler, A.3
Hug, H.4
Volkmann, M.5
Otto, G.6
Wesch, H.7
Mariani, S.M.8
Hack, V.9
Stremmel, W.10
-
113
-
-
10744232045
-
Placenta-derived CD95 ligand causes liver damage in hemolysis, elevated liver enzymes, and low platelet count syndrome
-
Strand S., Strand D, Seufert R, Mann A, Lotz J, Blessing M, Lahn M., Wunsch A, Broering DC, Hahn U, et al. 2004. Placenta-derived CD95 ligand causes liver damage in hemolysis, elevated liver enzymes, and low platelet count syndrome. Gastroenterology 126: 849-858.
-
(2004)
Gastroenterology
, vol.126
, pp. 849-858
-
-
Strand, S.1
Strand, D.2
Seufert, R.3
Mann, A.4
Lotz, J.5
Blessing, M.6
Lahn, M.7
Wunsch, A.8
Broering, D.C.9
Hahn, U.10
-
114
-
-
0028097822
-
Purification and characterization of the Fas-ligand that induces apoptosis
-
Suda T., Nagata S. 1994. Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med 179: 873-879.
-
(1994)
J Exp Med
, vol.179
, pp. 873-879
-
-
Suda, T.1
Nagata, S.2
-
115
-
-
0027145632
-
Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
-
Suda T., Takahashi T, Golstein P, Nagata S. 1993. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75: 1169-1178.
-
(1993)
Cell
, vol.75
, pp. 1169-1178
-
-
Suda, T.1
Takahashi, T.2
Golstein, P.3
Nagata, S.4
-
116
-
-
0028223847
-
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
-
Takahashi T., Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76: 969-976.
-
(1994)
Cell
, vol.76
, pp. 969-976
-
-
Takahashi, T.1
Tanaka, M.2
Brannan, C.I.3
Jenkins, N.A.4
Copeland, N.G.5
Suda, T.6
Nagata, S.7
-
117
-
-
0027275490
-
A novel domain within the 55 kd TNF receptor signals cell death
-
Tartaglia L.A., Ayres TM, Wong GH, Goeddel DV. 1993. A novel domain within the 55 kd TNF receptor signals cell death. Cell 74: 845-853.
-
(1993)
Cell
, vol.74
, pp. 845-853
-
-
Tartaglia, L.A.1
Ayres, T.M.2
Wong, G.H.3
Goeddel, D.V.4
-
118
-
-
70349967965
-
Anti-TNF biologic agents: Still the therapy of choice for rheumatoid arthritis
-
Taylor P.C., Feldmann M. 2009. Anti-TNF biologic agents: Still the therapy of choice for rheumatoid arthritis. Nat Rev Rheumatol 5: 578-582.
-
(2009)
Nat Rev Rheumatol
, vol.5
, pp. 578-582
-
-
Taylor, P.C.1
Feldmann, M.2
-
119
-
-
0030970013
-
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
-
Thome M., Schneider P, Hofmann K, Fickenscher H, Meinl E., Neipel F, Mattmann C, Burns K, Bodmer JL, Schroter M., et al. 1997. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 386: 517-521.
-
(1997)
Nature
, vol.386
, pp. 517-521
-
-
Thome, M.1
Schneider, P.2
Hofmann, K.3
Fickenscher, H.4
Meinl, E.5
Neipel, F.6
Mattmann, C.7
Burns, K.8
Bodmer, J.L.9
Schroter, M.10
-
120
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1b processing in monocytes
-
Thornberry N.A., Bull HG, Calaycay JR, Chapman KT, Howard A.D., Kostura MJ, Miller DK, Molineaux SM, Weidner J.R., Aunins J, et al. 1992. A novel heterodimeric cysteine protease is required for interleukin-1b processing in monocytes. Nature 356: 768-774.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weidner, J.R.9
Aunins, J.10
-
121
-
-
0024272982
-
Cachetin/TNF-a in septic shock and septic adult respiratory distress syndrome
-
Tracey K.J., Lowry SF, Cerami A. 1988. Cachetin/TNF-a in septic shock and septic adult respiratory distress syndrome. Am Rev Respir Dis 138: 1377-1379.
-
(1988)
Am Rev Respir Dis
, vol.138
, pp. 1377-1379
-
-
Tracey, K.J.1
Lowry, S.F.2
Cerami, A.3
-
122
-
-
0024347970
-
Monoclonal antibodymediated tumor regression by induction of apoptosis
-
Trauth B.C., Klas C, Peters AM, Matzku S, Moller P, Falk W, Debatin K.M., Krammer PH. 1989. Monoclonal antibodymediated tumor regression by induction of apoptosis. Science 245: 301-305.
-
(1989)
Science
, vol.245
, pp. 301-305
-
-
Trauth, B.C.1
Klas, C.2
Peters, A.M.3
Matzku, S.4
Moller, P.5
Falk, W.6
Debatin, K.M.7
Krammer, P.H.8
-
124
-
-
82755198022
-
Proliferative versus apoptotic functions of caspase-8 Hetero or homo: The caspase-8 dimer controls cell fate
-
van Raam BJ, Salvesen GS. 2012. Proliferative versus apoptotic functions of caspase-8 Hetero or homo: The caspase-8 dimer controls cell fate. Biochim Biophys Acta 1824: 113-122.
-
(2012)
Biochim Biophys Acta
, vol.1824
, pp. 113-122
-
-
van Raam, B.J.1
Salvesen, G.S.2
-
125
-
-
28844441555
-
Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
-
Varfolomeev E., Maecker H, Sharp D, Lawrence D, Renz M, Vucic D., Ashkenazi A. 2005. Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J Biol Chem 280: 40599-40608.
-
(2005)
J Biol Chem
, vol.280
, pp. 40599-40608
-
-
Varfolomeev, E.1
Maecker, H.2
Sharp, D.3
Lawrence, D.4
Renz, M.5
Vucic, D.6
Ashkenazi, A.7
-
126
-
-
0030589301
-
A major role for the Fas pathway in acute graft-versus-host disease
-
Via C.S., Nguyen P, Shustov A, Drappa J, Elkon KB. 1996a. A major role for the Fas pathway in acute graft-versus-host disease. J Immunol 157: 5387-5393.
-
(1996)
J Immunol
, vol.157
, pp. 5387-5393
-
-
Via, C.S.1
Nguyen, P.2
Shustov, A.3
Drappa, J.4
Elkon, K.B.5
-
127
-
-
0030293633
-
Differential effect of CTLA4Ig on murine graft-versus-host disease (GVHD) development: CTLA4Ig prevents both acute and chronic GVHD development but reverses only chronic GVHD
-
Via C.S., Rus V, Nguyen P, Linsley P, Gause WC. 1996b. Differential effect of CTLA4Ig on murine graft-versus-host disease (GVHD) development: CTLA4Ig prevents both acute and chronic GVHD development but reverses only chronic GVHD. J Immunol 157: 4258-4267.
-
(1996)
J Immunol
, vol.157
, pp. 4258-4267
-
-
Via, C.S.1
Rus, V.2
Nguyen, P.3
Linsley, P.4
Gause, W.C.5
-
128
-
-
84857404572
-
Inhibitor of apoptosis proteins limit RIP3 kinasedependent interleukin-1 activation
-
Vince J.E., Wong WW, Gentle I, Lawlor KE, Allam R, O'Reilly L, Mason K, Gross O, Ma S, Guarda G, et al. 2012. Inhibitor of apoptosis proteins limit RIP3 kinasedependent interleukin-1 activation. Immunity 36: 215-227.
-
(2012)
Immunity
, vol.36
, pp. 215-227
-
-
Vince, J.E.1
Wong, W.W.2
Gentle, I.3
Lawlor, K.E.4
Allam, R.5
O'Reilly, L.6
Mason, K.7
Gross, O.8
Ma, S.9
Guarda, G.10
-
129
-
-
0032486355
-
Oxidative stress and hypoxia/reoxygenation trigger CD95 (APO-1/Fas) ligand expression in microglial cells
-
Vogt M., Bauer MK, Ferrari D, Schulze-Osthoff K. 1998. Oxidative stress and hypoxia/reoxygenation trigger CD95 (APO-1/Fas) ligand expression in microglial cells. FEBS Lett 429: 67-72.
-
(1998)
FEBS Lett
, vol.429
, pp. 67-72
-
-
Vogt, M.1
Bauer, M.K.2
Ferrari, D.3
Schulze-Osthoff, K.4
-
131
-
-
80054852212
-
TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer
-
Walczak H. 2011. TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer. Immunol Rev 244: 9-28.
-
(2011)
Immunol Rev
, vol.244
, pp. 9-28
-
-
Walczak, H.1
-
132
-
-
0034630161
-
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
-
Walczak H., Krammer PH. 2000. The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res 256: 58-66.
-
(2000)
Exp Cell Res
, vol.256
, pp. 58-66
-
-
Walczak, H.1
Krammer, P.H.2
-
133
-
-
0030880548
-
TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL
-
Walczak H., Degli-Esposti MA, Johnson RS, Smolak PJ, Waugh J.Y., Boiani N, Timour MS, Gerhart MJ, Schooley K.A., Smith CA, et al. 1997. TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL. EMBO J 16: 5386-5397.
-
(1997)
EMBO J
, vol.16
, pp. 5386-5397
-
-
Walczak, H.1
Degli-Esposti, M.A.2
Johnson, R.S.3
Smolak, P.J.4
Waugh, J.Y.5
Boiani, N.6
Timour, M.S.7
Gerhart, M.J.8
Schooley, K.A.9
Smith, C.A.10
-
134
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
Walczak H., Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M., Chin W, Jones J, Woodward A, Le T, et al. 1999. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 5: 157-163.
-
(1999)
Nat Med
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
Chin, W.7
Jones, J.8
Woodward, A.9
Le, T.10
-
135
-
-
82455212812
-
Necrosome-induced inflammation: Must cells die for it?
-
Wallach D., Kovalenko A, Kang TB. 2012. ""Necrosome"-induced inflammation: Must cells die for it? Trends Immunol 32: 505-509.
-
(2012)
Trends Immunol
, vol.32
, pp. 505-509
-
-
Wallach, D.1
Kovalenko, A.2
Kang, T.B.3
-
136
-
-
0026568919
-
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
-
Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins N.A., Nagata S. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356: 314-317.
-
(1992)
Nature
, vol.356
, pp. 314-317
-
-
Watanabe-Fukunaga, R.1
Brannan, C.I.2
Copeland, N.G.3
Jenkins, N.A.4
Nagata, S.5
-
137
-
-
80052850704
-
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
-
Welz P.S., Wullaert A, Vlantis K, Kondylis V, Fernandez-Majada V., Ermolaeva M, Kirsch P, Sterner-Kock A, van Loo G., Pasparakis M. 2011. FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature 477: 330-334.
-
(2011)
Nature
, vol.477
, pp. 330-334
-
-
Welz, P.S.1
Wullaert, A.2
Vlantis, K.3
Kondylis, V.4
Fernandez-Majada, V.5
Ermolaeva, M.6
Kirsch, P.7
Sterner-Kock, A.8
van Loo, G.9
Pasparakis, M.10
-
138
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley S.R., Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl J.K., Sutherland GR, Smith TD, Rauch C, Smith C.A., et al. 1995. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3: 673-682.
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.P.5
Nicholl, J.K.6
Sutherland, G.R.7
Smith, T.D.8
Rauch, C.9
Smith, C.A.10
-
139
-
-
0026644298
-
Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
-
Williams R.O., Feldmann M, Maini RN. 1992. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci 89: 9784-9788.
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 9784-9788
-
-
Williams, R.O.1
Feldmann, M.2
Maini, R.N.3
-
140
-
-
62849093368
-
Death receptor signal transducers: Nodes of coordination in immune signaling networks
-
Wilson N.S., Dixit V, Ashkenazi A. 2009. Death receptor signal transducers: Nodes of coordination in immune signaling networks. Nat Immunol 10: 348-355.
-
(2009)
Nat Immunol
, vol.10
, pp. 348-355
-
-
Wilson, N.S.1
Dixit, V.2
Ashkenazi, A.3
-
141
-
-
78651466506
-
An Fcg receptor-dependent mechanism drives antibodymediated target-receptor signaling in cancer cells
-
Wilson N.S., Yang B, Yang A, Loeser S, Marsters S, Lawrence D, Li Y, Pitti R, Totpal K, Yee S, et al. 2011. An Fcg receptor-dependent mechanism drives antibodymediated target-receptor signaling in cancer cells. Cancer Cell 19: 101-113.
-
(2011)
Cancer Cell
, vol.19
, pp. 101-113
-
-
Wilson, N.S.1
Yang, B.2
Yang, A.3
Loeser, S.4
Marsters, S.5
Lawrence, D.6
Li, Y.7
Pitti, R.8
Totpal, K.9
Yee, S.10
-
142
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
Wu G.S., Burns TF, McDonald ER 3rd, Jiang W, Meng R, Krantz I.D., Kao G, Gan DD, Zhou JY, Muschel R, et al. 1997. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 17: 141-143.
-
(1997)
Nat Genet
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald III, E.R.3
Jiang, W.4
Meng, R.5
Krantz, I.D.6
Kao, G.7
Gan, D.D.8
Zhou, J.Y.9
Muschel, R.10
-
143
-
-
0033662341
-
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
-
Yeh W.C., Itie A, Elia AJ, Ng M, Shu HB, Wakeham A, Mirtsos C., Suzuki N, Bonnard M, Goeddel DV, et al. 2000. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 12: 633-642.
-
(2000)
Immunity
, vol.12
, pp. 633-642
-
-
Yeh, W.C.1
Itie, A.2
Elia, A.J.3
Ng, M.4
Shu, H.B.5
Wakeham, A.6
Mirtsos, C.7
Suzuki, N.8
Bonnard, M.9
Goeddel, D.V.10
-
144
-
-
0033607006
-
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
-
Yin X.M., Wang K, Gross A, Zhao Y, Zinkel S, Klocke B, Roth K.A., Korsmeyer SJ. 1999. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature 400: 886-891.
-
(1999)
Nature
, vol.400
, pp. 886-891
-
-
Yin, X.M.1
Wang, K.2
Gross, A.3
Zhao, Y.4
Zinkel, S.5
Klocke, B.6
Roth, K.A.7
Korsmeyer, S.J.8
-
145
-
-
0024596722
-
A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen codownregulated with the receptor of tumor necrosis factor
-
Yonehara S., Ishii A, Yonehara M. 1989. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen codownregulated with the receptor of tumor necrosis factor. J Exp Med 169: 1747-1756.
-
(1989)
J Exp Med
, vol.169
, pp. 1747-1756
-
-
Yonehara, S.1
Ishii, A.2
Yonehara, M.3
-
146
-
-
0025255636
-
The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death
-
Yuan J.Y., Horvitz HR. 1990. The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev Biol 138: 33-41.
-
(1990)
Dev Biol
, vol.138
, pp. 33-41
-
-
Yuan, J.Y.1
Horvitz, H.R.2
-
147
-
-
0027525104
-
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 β-converting enzyme
-
Yuan J., Shaham S, Ledoux S, Ellis HM, Horvitz HR. 1993. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 β-converting enzyme. Cell 75: 641-652.
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
Ellis, H.M.4
Horvitz, H.R.5
-
148
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, Dong MQ, Han J. 2009. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325: 332-336.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
Dong, M.Q.7
Han, J.8
-
149
-
-
79952780505
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes
-
Zhang H., Zhou X, McQuade T, Li J, Chan FK, Zhang J. 2011. Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 471: 373-376.
-
(2011)
Nature
, vol.471
, pp. 373-376
-
-
Zhang, H.1
Zhou, X.2
McQuade, T.3
Li, J.4
Chan, F.K.5
Zhang, J.6
|