메뉴 건너뛰기




Volumn 43, Issue 2, 1999, Pages 398-407

Doxorubicin induces slow ceramide accumulation and late apoptosis in cultured adult rat ventricular myocytes

Author keywords

Apoptosis; Cardiomyopathy; Heart failure; Myocytes

Indexed keywords

ANTHRACYCLINE; CERAMIDE; DAUNORUBICIN; DNA FRAGMENT; DOXORUBICIN;

EID: 0033178928     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(99)00142-X     Document Type: Article
Times cited : (82)

References (41)
  • 1
    • 0025051505 scopus 로고
    • Doxorubicin cardiotoxicity: Analysis of prevailing hypotheses
    • Olson R.D., Mushlin P.S. Doxorubicin cardiotoxicity: analysis of prevailing hypotheses. FASEB J. 4:1990;3076-3086.
    • (1990) FASEB J , vol.4 , pp. 3076-3086
    • Olson, R.D.1    Mushlin, P.S.2
  • 2
    • 0030317942 scopus 로고    scopus 로고
    • Anthracylcine-induced cardiotoxicity
    • Shan K., Lincoff M., Young J.B. Anthracylcine-induced cardiotoxicity. Ann Intern Med. 125:1996;47-58.
    • (1996) Ann Intern Med , vol.125 , pp. 47-58
    • Shan, K.1    Lincoff, M.2    Young, J.B.3
  • 3
    • 0027278808 scopus 로고
    • Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells
    • Ling Y.H., Priebe W., Perez-Soler R. Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells. Cancer Res. 53:1993;1845-1852.
    • (1993) Cancer Res , vol.53 , pp. 1845-1852
    • Ling, Y.H.1    Priebe, W.2    Perez-Soler, R.3
  • 4
    • 0027237540 scopus 로고
    • Adriamycin and daunomycin induced programmed cell death (apoptosis) in tumour cells
    • Skladanowski A., Konopa J. Adriamycin and daunomycin induced programmed cell death (apoptosis) in tumour cells. Biochem Pharmacol. 46:1993;375-382.
    • (1993) Biochem Pharmacol , vol.46 , pp. 375-382
    • Skladanowski, A.1    Konopa, J.2
  • 5
    • 0032494175 scopus 로고    scopus 로고
    • Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I
    • Wang L., Ma W., Markovich R., Chen J.W., Wang P.H. Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I. Circ Res. 83:1998;516-522.
    • (1998) Circ Res , vol.83 , pp. 516-522
    • Wang, L.1    Ma, W.2    Markovich, R.3    Chen, J.W.4    Wang, P.H.5
  • 6
    • 0038985463 scopus 로고    scopus 로고
    • Stress-induced apoptosis and the sphingomyelin pathway
    • Pena L.A., Fuks Z., Kolesnick R. Stress-induced apoptosis and the sphingomyelin pathway. Biochem Pharmacol. 53:1997;615-621.
    • (1997) Biochem Pharmacol , vol.53 , pp. 615-621
    • Pena, L.A.1    Fuks, Z.2    Kolesnick, R.3
  • 7
    • 0030634437 scopus 로고    scopus 로고
    • Ceramide: A novel lipid mediator of apoptosis
    • Smyth M.J., Obeid L.M., Hannun Y.A. Ceramide: a novel lipid mediator of apoptosis. Adv Pharmacol. 41:1997;133-154.
    • (1997) Adv Pharmacol , vol.41 , pp. 133-154
    • Smyth, M.J.1    Obeid, L.M.2    Hannun, Y.A.3
  • 8
    • 0031919157 scopus 로고    scopus 로고
    • Regulation of ceramide production and apoptosis
    • Kolesnik R.N., Krönke M. Regulation of ceramide production and apoptosis. Annu Rev Physiol. 60:1998;643-665.
    • (1998) Annu Rev Physiol , vol.60 , pp. 643-665
    • Kolesnik, R.N.1    Krönke, M.2
  • 9
    • 0030453430 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes
    • Krown K.A., Page M.T., Nguyen C., et al. Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. J Clin Invest. 98:1996;2854-2865.
    • (1996) J Clin Invest , vol.98 , pp. 2854-2865
    • Krown, K.A.1    Page, M.T.2    Nguyen, C.3
  • 10
    • 0030698045 scopus 로고    scopus 로고
    • Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion
    • Bielawska A.E., Shapiro J.P., Jiang L., et al. Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion. Am J Pathol. 151:1997;1257-1263.
    • (1997) Am J Pathol , vol.151 , pp. 1257-1263
    • Bielawska, A.E.1    Shapiro, J.P.2    Jiang, L.3
  • 11
    • 0029148660 scopus 로고
    • Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
    • Bose R., Verjeiij M., Haimowitz-Friedman A., et al. Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell. 82:1995;405-414.
    • (1995) Cell , vol.82 , pp. 405-414
    • Bose, R.1    Verjeiij, M.2    Haimowitz-Friedman, A.3
  • 12
    • 0030006040 scopus 로고    scopus 로고
    • Daunorubicin-induced apoptosis: Triggering of ceramide generation though sphingomyelin hydrolysis
    • Jaffrézou J.P., Levade T., Bettaieb A., et al. Daunorubicin-induced apoptosis: triggering of ceramide generation though sphingomyelin hydrolysis. EMBO J. 15:1996;2417-2424.
    • (1996) EMBO J , vol.15 , pp. 2417-2424
    • Jaffrézou, J.P.1    Levade, T.2    Bettaieb, A.3
  • 13
    • 0024212836 scopus 로고
    • Immunocytochemical analysis of the regeneration of myofibrills in long-term cultures of adult cardiomyocytes of the rat
    • Eppenberger M.E., Hauser I., Baechi T., et al. Immunocytochemical analysis of the regeneration of myofibrills in long-term cultures of adult cardiomyocytes of the rat. Dev Biol. 130:1988;1-15.
    • (1988) Dev Biol , vol.130 , pp. 1-15
    • Eppenberger, M.E.1    Hauser, I.2    Baechi, T.3
  • 15
    • 0345299198 scopus 로고    scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine during apoptosis of adult rat ventricular myocytes in vitro
    • in press
    • Rücker-Martin C, Hénaff M, Hatem SN, Delpy E, Mercadier JJ. Early redistribution of plasma membrane phosphatidylserine during apoptosis of adult rat ventricular myocytes in vitro. Basic Res Cardiol 1999;in press.
    • (1999) Basic Res Cardiol
    • Rücker-Martin, C.1    Hénaff, M.2    Hatem, S.N.3    Delpy, E.4    Mercadier, J.J.5
  • 16
    • 0025194895 scopus 로고
    • β-Adrenergic agonists stimulate the synthesis of noncontractile but not contractile proteins in cultured myocytes isolated from adult rat heart
    • Dubus I., Samuel J.L., Marotte F., Delcayre C., Rappaport L. β-Adrenergic agonists stimulate the synthesis of noncontractile but not contractile proteins in cultured myocytes isolated from adult rat heart. Circ Res. 66:1990;867-874.
    • (1990) Circ Res , vol.66 , pp. 867-874
    • Dubus, I.1    Samuel, J.L.2    Marotte, F.3    Delcayre, C.4    Rappaport, L.5
  • 17
    • 0027512102 scopus 로고
    • A safe and rapid method for analysing apoptotic-induced fragmentation of DNA extracted from tissues or cultured cells
    • Prigent P., Blanpied C., Aten J., Hirsch F. A safe and rapid method for analysing apoptotic-induced fragmentation of DNA extracted from tissues or cultured cells. J Immunol Methods. 160:1993;139-140.
    • (1993) J Immunol Methods , vol.160 , pp. 139-140
    • Prigent, P.1    Blanpied, C.2    Aten, J.3    Hirsch, F.4
  • 19
    • 0025908397 scopus 로고
    • Myocardial adrenergic changes at two stages of heart failure due to adriamycin treatment in rats
    • Tong J., Ganguly P.K., Singal P.K. Myocardial adrenergic changes at two stages of heart failure due to adriamycin treatment in rats. Am J Physiol. 260:1991;H909-H916.
    • (1991) Am J Physiol , vol.260
    • Tong, J.1    Ganguly, P.K.2    Singal, P.K.3
  • 20
    • 0023258056 scopus 로고
    • Preparation of the active isomer of 1-pheny-2-decanoylamino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthetase
    • Inokuchi J., Radin N.S. Preparation of the active isomer of 1-pheny-2-decanoylamino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthetase. J Lipid Res. 28:1987;565-571.
    • (1987) J Lipid Res , vol.28 , pp. 565-571
    • Inokuchi, J.1    Radin, N.S.2
  • 21
    • 0028878829 scopus 로고
    • Cell cycle arrest induced by an inhibitor of glucosylceramide synthase
    • Rani C.S.S., Abe A., Chang Y., et al. Cell cycle arrest induced by an inhibitor of glucosylceramide synthase. J Biol Chem. 270:1995;2859-2867.
    • (1995) J Biol Chem , vol.270 , pp. 2859-2867
    • Rani, C.S.S.1    Abe, A.2    Chang, Y.3
  • 22
    • 85047680306 scopus 로고
    • Improvement of doxorubicin-induced cardiomyopathy in rats treated with insulin-like growth factor I
    • Ambler G.R., Johnston B.M., Maxwell L., Gavin J.B., Gluckman P.D. Improvement of doxorubicin-induced cardiomyopathy in rats treated with insulin-like growth factor I. Cardiovasc Res. 27:1993;1368-1373.
    • (1993) Cardiovasc Res , vol.27 , pp. 1368-1373
    • Ambler, G.R.1    Johnston, B.M.2    Maxwell, L.3    Gavin, J.B.4    Gluckman, P.D.5
  • 24
    • 0027327212 scopus 로고
    • Tumor necrosis factor-α (TNF-α) signal transduction through ceramide. Dissociation of growth inhibitory effect of TNF-α From activation with nuclear factor kB
    • Dbaido G.S., Obeid L.M., Hannun Y.A. Tumor necrosis factor-α (TNF-α) signal transduction through ceramide. Dissociation of growth inhibitory effect of TNF-α from activation with nuclear factor kB. J Biol Chem. 268:1993;17762-17766.
    • (1993) J Biol Chem , vol.268 , pp. 17762-17766
    • Dbaido, G.S.1    Obeid, L.M.2    Hannun, Y.A.3
  • 25
    • 0032054080 scopus 로고    scopus 로고
    • Co-localization of cysteine protease caspase-3 with apoptotic myocytes after in vivo myocardial ischemia and reperfusion in the rat
    • Black S.C., Huang J.Q., Rezaiefar P., et al. Co-localization of cysteine protease caspase-3 with apoptotic myocytes after in vivo myocardial ischemia and reperfusion in the rat. J Mol Cell Cardiol. 30:1998;733-742.
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 733-742
    • Black, S.C.1    Huang, J.Q.2    Rezaiefar, P.3
  • 27
    • 0029949938 scopus 로고    scopus 로고
    • PrICE: A downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2
    • Smyth M.J., Perry D.K., Zhang J., et al. prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2. Biochem J. 316:1996;25-28.
    • (1996) Biochem J , vol.316 , pp. 25-28
    • Smyth, M.J.1    Perry, D.K.2    Zhang, J.3
  • 28
    • 0001739436 scopus 로고    scopus 로고
    • Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell
    • Leri A., Claudio P.P., Li Q., et al. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest. 101:1998;1326-1342.
    • (1998) J Clin Invest , vol.101 , pp. 1326-1342
    • Leri, A.1    Claudio, P.P.2    Li, Q.3
  • 29
    • 0027935409 scopus 로고
    • Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes
    • Tanaka M., Ito H., Adachi S., et al. Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circ Res. 75:1994;426-433.
    • (1994) Circ Res , vol.75 , pp. 426-433
    • Tanaka, M.1    Ito, H.2    Adachi, S.3
  • 30
    • 0032498614 scopus 로고    scopus 로고
    • Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol
    • Yue T.L., Ma X.L., Wang X., et al. Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol. Circ Res. 82:1998;166-174.
    • (1998) Circ Res , vol.82 , pp. 166-174
    • Yue, T.L.1    Ma, X.L.2    Wang, X.3
  • 31
    • 0030670626 scopus 로고    scopus 로고
    • Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
    • Herr I., Wilhelm D., Böhler T., Angel P., Debatin K.M. Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis. EMBO J. 16:1997;6200-6208.
    • (1997) EMBO J , vol.16 , pp. 6200-6208
    • Herr, I.1    Wilhelm, D.2    Böhler, T.3    Angel, P.4    Debatin, K.M.5
  • 32
    • 0347537940 scopus 로고    scopus 로고
    • Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
    • Verheij M., Bose R., Lin X.H., et al. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature. 380:1996;75-79.
    • (1996) Nature , vol.380 , pp. 75-79
    • Verheij, M.1    Bose, R.2    Lin, X.H.3
  • 33
    • 0019817511 scopus 로고
    • Mechanism of adriamycin cardiotoxicity: Evidence for oxidative stress
    • Olson R.D., Boerth R.C., Gerber J.G., Nies A.S. Mechanism of adriamycin cardiotoxicity: evidence for oxidative stress. Life Sci. 29:1981;1393-1401.
    • (1981) Life Sci , vol.29 , pp. 1393-1401
    • Olson, R.D.1    Boerth, R.C.2    Gerber, J.G.3    Nies, A.S.4
  • 34
    • 1842375100 scopus 로고    scopus 로고
    • Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis
    • Quillet-Mary A., Jaffrézou J.P., Mansat V., et al. Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis. J Biol Chem. 272:1997;21388-21395.
    • (1997) J Biol Chem , vol.272 , pp. 21388-21395
    • Quillet-Mary, A.1    Jaffrézou, J.P.2    Mansat, V.3
  • 35
    • 0030803878 scopus 로고    scopus 로고
    • Insulin-like growth factor-I rapidly activates multiple signal transduction pathways in cultured rat cardiac myocytes
    • Foncea R., Andersson M., Ketterman A., et al. Insulin-like growth factor-I rapidly activates multiple signal transduction pathways in cultured rat cardiac myocytes. J Biol Chem. 272:1997;19115-19124.
    • (1997) J Biol Chem , vol.272 , pp. 19115-19124
    • Foncea, R.1    Andersson, M.2    Ketterman, A.3
  • 36
    • 1842376234 scopus 로고    scopus 로고
    • Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin
    • Mansat V., Bettaieb A., Levade T., Laurent G., Jaffrézou J.P. Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin. FASEB J. 11:1997;695-702.
    • (1997) FASEB J , vol.11 , pp. 695-702
    • Mansat, V.1    Bettaieb, A.2    Levade, T.3    Laurent, G.4    Jaffrézou, J.P.5
  • 37
    • 0030248675 scopus 로고    scopus 로고
    • Doxorubicin-induced apoptosis in spontaneously hypertensive rats: Differential effects in heart, kidney and intestine, and inhibition by ICRF-187
    • Zhang J., Clark J.R. Jr., Herman E.H., Ferrans V.J. Doxorubicin-induced apoptosis in spontaneously hypertensive rats: differential effects in heart, kidney and intestine, and inhibition by ICRF-187. J Mol Cell Cardiol. 28:1996;1931-1943.
    • (1996) J Mol Cell Cardiol , vol.28 , pp. 1931-1943
    • Zhang, J.1    Clark J.R., Jr.2    Herman, E.H.3    Ferrans, V.J.4
  • 38
    • 0029002097 scopus 로고
    • Cardiac failure and dysrhythmias 6-19 years after anthracycline therapy: A series of 15 patients
    • Steinhertz L.J., Steinhertz P.G., Tan C. Cardiac failure and dysrhythmias 6-19 years after anthracycline therapy: a series of 15 patients. Med Pediatr Oncol. 24:1995;352-361.
    • (1995) Med Pediatr Oncol , vol.24 , pp. 352-361
    • Steinhertz, L.J.1    Steinhertz, P.G.2    Tan, C.3
  • 39
    • 0031047983 scopus 로고    scopus 로고
    • Molecular mechanisms of doxorubicin-induced cardiomyopathy. Selective suppression of reiske iron-sulfur protein. ADP/ATP translocase, and phosphofructokinase genes is associated with ATP depletion in rat cardiomyocytes
    • Jeyaseelan R., Poizat C., Wu H.Y., Kedes L. Molecular mechanisms of doxorubicin-induced cardiomyopathy. Selective suppression of reiske iron-sulfur protein. ADP/ATP translocase, and phosphofructokinase genes is associated with ATP depletion in rat cardiomyocytes. J Biol Chem. 272:1997;5828-5832.
    • (1997) J Biol Chem , vol.272 , pp. 5828-5832
    • Jeyaseelan, R.1    Poizat, C.2    Wu, H.Y.3    Kedes, L.4
  • 40
    • 0031015354 scopus 로고    scopus 로고
    • Involvement of phosphorylation in doxorubicin-mediated myofibril degeneration
    • Sussman M.A., Hamm-Alvarez S.H., Vilalta P.M., Welsh S., Kedes L. Involvement of phosphorylation in doxorubicin-mediated myofibril degeneration. Circ Res. 80:1997;52-61.
    • (1997) Circ Res , vol.80 , pp. 52-61
    • Sussman, M.A.1    Hamm-Alvarez, S.H.2    Vilalta, P.M.3    Welsh, S.4    Kedes, L.5
  • 41
    • 0031035381 scopus 로고    scopus 로고
    • Ceramide-induced translocation of protein kinase C-δ And -ε To the cytosol. Implication in apoptosis
    • Sawai H., Okazaki T., Takeda Y., et al. Ceramide-induced translocation of protein kinase C-δ and -ε to the cytosol. Implication in apoptosis. J Biol Chem. 272:1997;2452-2458.
    • (1997) J Biol Chem , vol.272 , pp. 2452-2458
    • Sawai, H.1    Okazaki, T.2    Takeda, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.