Niacin status impacts chromatin structure

Journal of Nutrition

Volumn 139, Issue 12, 2009, Pages 2397-2401

  Kirkland, James B ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; ADENOSINE DIPHOSPHATE RIBOSE ACETATE; CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; HISTONE; HISTONE H1; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE; NICOTINIC ACID; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN P53; SIRTUIN; TANKYRASE; TELOMERIC REPEAT BINDING FACTOR 1; TELOMERIC REPEAT BINDING FACTOR 2;

APOPTOSIS; BINDING AFFINITY; BONE MARROW CELL; CALORIC RESTRICTION; CANCER RISK; CELL DIFFERENTIATION; CELL DIVISION; CELL METABOLISM; CHROMATIN STRUCTURE; CHROMOSOMAL INSTABILITY; CONFERENCE PAPER; COVALENT BOND; DEACETYLATION; DIET; DNA BINDING; DNA REPAIR; DNA STRAND BREAKAGE; EXCISION REPAIR; GENE OVEREXPRESSION; GENOMIC INSTABILITY; HUMAN; NICOTINIC ACID DEFICIENCY; OXIDATION REDUCTION REACTION; PROTEIN EXPRESSION; TELOMERE;

ADENOSINE DIPHOSPHATE RIBOSE; CHROMATIN; DIET; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HISTONES; HUMANS; NAD; NIACIN; NIACINAMIDE; POLY(ADP-RIBOSE) POLYMERASES; SIRTUINS;

EID: 72249115358     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.109.111757     Document Type: Conference Paper

References (34)

1. Kirkland JB. Niacin status, NAD distribution and ADP-ribose metabolism. Curr Pharm Des. 2009;15:3-11.
2. Kirkland JB. Niacin. In: Rucker R, Zempleni J, Suttie JW, McCormick DB, eds. Handbook of Vitamins, 4th Edition. New York: Taylor and Francis; 2007. p. 191-232.
3. Shah GM, Le Rhun Y, Sutarjono I, Kirkland JB. Niacin deficient SKH- 1 mice are more susceptible to ultraviolet B radiation-induced skin carcinogenesis. J Nutr. 2001;131: 11S:3150S.
4. Young GS, Kirkland JB. The role of dietary niacin intake and the adenosine-59-diphosphate-ribosyl cyclase enzyme CD38 in spatial learning ability: is cyclic adenosine diphosphate ribose the link between diet and behaviour? Nutr Res Rev. 2008;21:42-55.
5. Jacobson EL. Niacin deficiency and cancer in women. J Am Coll Nutr. 1993;12:412-416
6. Ame JC, Spenlehauer C, de Murcia G. The PARP superfamily. Bioessays. 2004;26:882-893
7. Rouleau M, Aubin RA, Poirier GG. Poly(ADP-ribosyl)ated chromatin domains: access granted. J Cell Sci. 2004;117:815-825 (Pubitemid 38386940)
8. Quénet D, El Ramy R, Schreiber V, Dantzer F. The role of poly(ADPribosyl) ation in epigenetic events. Int J Biochem Cell Biol. 2009;41:60-65
9. Huletsky A, de Murcia G, Muller S, Hengartner M, Menard L, Lamarre D, Poirier GG. The effect of poly(ADP-ribosyl)ation on native and H1- depleted chromatin. A role of poly(ADP-ribosyl)ation on core nucleosome structure. J Biol Chem. 1989;264:8878-8886 (Pubitemid 19151612)
10. Thomassin H, Menard L, Hengartner C, Kirkland JB, Poirier GG. Poly (ADP-ribosyl)ation of chromatin in an in-vitro poly(ADP-ribose)- turnover system. Biochim Biophys Acta. 1992;1137:171-181
11. Tulin A, Spradling A. Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci. Science. 2003;299: 560-562 (Pubitemid 36135152)
12. Althaus FR, Hofferer L, Kleczkowska HE, Malanga M, Naegeli H, Panzeter P, Realini C. Histone shuttle driven by the automodification cycle of poly(ADP-ribose)polymerase. Environ Mol Mutagen. 1993;22:278-282 (Pubitemid 23359330)
13. Hsiao SJ, Smith S. Tankyrase function at telomeres, spindle poles, and beyond. Biochimie. 2008;90:83-92. (Pubitemid 350216209)
14. Chiang YJ, Hsiao SJ, Yver D, Cushman SW, Tessarollo L, Smith S, Hodes RJ. Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development. PLoS One. 2008;3:e2639.
15. Rippmann JF, Damm K, Schnapp A. Functional characterization of the poly(ADP-ribose) polymerase activity of tankyrase 1, a potential regulator of telomere length. J Mol Biol. 2002;323:217-224 (Pubitemid 35283687)
16. Dali-Youcef N, Lagouge M, Froelich S, Koehl C, Schoonjans K, Auwerx J. Sirtuins: the "magnificent seven," function, metabolism and longevity. Ann Med. 2007;39:335-345
17. Spange S, Wagner T, Heinzel T, Kramer OH. Acetylation of non-histone proteins modulates cellular signalling at multiple levels. Int J Biochem Cell Biol. 2009;41:185-198
18. Schmidt MT, Smith BC, Jackson MD, Denu JM. Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation. J Biol Chem. 2004;279:40122-40129 (Pubitemid 39258287)
19. Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003;425: 191-196 (Pubitemid 37150899)
20. Boyonoski AC, Spronck JC, Gallacher LM, Jacobs RM, Shah GM, Poirier GG, Kirkland JB. Niacin deficiency decreases bone marrow poly (ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats. J Nutr. 2002;132:108-114 (Pubitemid 34042463)
21. Boyonoski AC, Spronck JC, Jacobs RM, Shah GM, Poirier GG, Kirkland JB. Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats. J Nutr. 2002;132:115-120 (Pubitemid 34042464)
22. Fu CS, Swendseid ME, Jacob RA, McKee RW. Biochemical markers for assessment of niacin status in young men: levels of erythrocyte niacin coenzymes and plasma tryptophan. J Nutr. 1989;119:1949-1955 (Pubitemid 20063889)
23. Jacobson EL, Nunbhakdi-Craig V, Smith DG, Chen HY, Wasson BL, Jacobson MK. ADP-ribose polymer metabolism: implications for human nutrition. In: Poirier GG, Moreau P, eds. ADP-Ribosylation Reactions. New York: Springer-Verlag; 1992. p. 153-162.
24. Kostecki LM, Thomas M, Linford G, Lizotte M, Toxopeus L, Bartleman AP, Kirkland JB. Niacin deficiency delays DNA excision repair and increases spontaneous and nitrosourea-induced chromosomal instability in rat bone marrow. Mutat Res. 2007;625:50-61. (Pubitemid 350016105)
25. Spronck JC, Nickerson JL, Kirkland JB. Niacin deficiency alters p53 expression and impairs etoposide-induced cell cycle arrest and apoptosis in rat bone marrow cells. Nutr Cancer. 2007;57:88-99.
26. Bartleman AP, Jacobs R, Kirkland JB. Niacin supplementation decreases the incidence of alkylation-induced nonlymphocytic leukemia in Long- Evans rats. Nutr Cancer. 2008;60:251-258
27. Kirkland JB. Niacin and carcinogenesis. Nutr Cancer. 2003;46:110-118
28. + consumption by SIRT1 may endanger energetically compromised neurons. Neuromolecular Med. 2009;11:28-42.
29. Berger F, Lau C, Ziegler M. Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1. Proc Natl Acad Sci USA. 2007;104:3765-3770 (Pubitemid 47181528)
30. + salvage pathway regulate SIRT1 activity at target gene promoters. J Biol Chem. 2009;284:20408-20417
31. Ho E, Zempleni J. Overview to symposium "Nutrients and Epigenetic Regulation of Gene Expression.". J Nutr. 2009;139:2387-2388
32. Zempleni J, Chew YC, Bao B, Pestinger V, Wijeratne SSK. Repression of transposable elements by histone biotinylation. J Nutr. 2009;139:2389-2392
33. Ho E, Clarke JD, Dashwood RH. Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention. J Nutr. 2009;139:2393-2396
34. Stover PJ. One-carbon metabolism-genome interactions in folateassociated pathologies. J Nutr. 2009;139:2402-2405