-
1
-
-
0024805768
-
DNA-intercalating ligands as anti-cancer drugs: Prospects for future design
-
W.A. Denny DNA-intercalating ligands as anti-cancer drugs: prospects for future design Anticancer Drug Des. 4 1989 241 263
-
(1989)
Anticancer Drug Des.
, vol.4
, pp. 241-263
-
-
Denny, W.A.1
-
2
-
-
77952996319
-
Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones
-
R.B. Deal, J.G. Henikoff, and S. Henikoff Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones Science 328 2010 1161 1164
-
(2010)
Science
, vol.328
, pp. 1161-1164
-
-
Deal, R.B.1
Henikoff, J.G.2
Henikoff, S.3
-
3
-
-
84865461059
-
Measuring genome-wide nucleosome turnover using CATCH-IT
-
S.S. Teves, R.B. Deal, and S. Henikoff Measuring genome-wide nucleosome turnover using CATCH-IT Methods Enzymol. 513 2012 169 184
-
(2012)
Methods Enzymol.
, vol.513
, pp. 169-184
-
-
Teves, S.S.1
Deal, R.B.2
Henikoff, S.3
-
4
-
-
81055135515
-
Heat shock reduces stalled RNA polymerase II and nucleosome turnover genome-wide
-
S.S. Teves, and S. Henikoff Heat shock reduces stalled RNA polymerase II and nucleosome turnover genome-wide Genes Dev. 25 2011 2387 2397
-
(2011)
Genes Dev.
, vol.25
, pp. 2387-2397
-
-
Teves, S.S.1
Henikoff, S.2
-
5
-
-
24944535307
-
Multistep skin cancer in mice as a model to study the evolution of cancer cells
-
C.J. Kemp Multistep skin cancer in mice as a model to study the evolution of cancer cells Semin. Cancer Biol. 15 2005 460 473
-
(2005)
Semin. Cancer Biol.
, vol.15
, pp. 460-473
-
-
Kemp, C.J.1
-
6
-
-
70249123827
-
Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications
-
E.L. Abel, J.M. Angel, K. Kiguchi, and J. DiGiovanni Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications Nat. Protoc. 4 2009 1350 1362
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1350-1362
-
-
Abel, E.L.1
Angel, J.M.2
Kiguchi, K.3
Digiovanni, J.4
-
7
-
-
51649121555
-
Tumor suppression by p53 in the absence of Atm
-
S.L. Bailey, K.E. Gurley, K. Hoon-Kim, K.S. Kelly-Spratt, and C.J. Kemp Tumor suppression by p53 in the absence of Atm Mol. Cancer Res. 6 2008 1185 1192
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 1185-1192
-
-
Bailey, S.L.1
Gurley, K.E.2
Hoon-Kim, K.3
Kelly-Spratt, K.S.4
Kemp, C.J.5
-
8
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
A. Barski, S. Cuddapah, K. Cui, T.Y. Roh, D.E. Schones, Z. Wang, G. Wei, I. Chepelev, and K. Zhao High-resolution profiling of histone methylations in the human genome Cell 129 2007 823 837
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
9
-
-
77951956458
-
Pol II and its associated epigenetic marks are present at Pol III-transcribed noncoding RNA genes
-
A. Barski, I. Chepelev, D. Liko, S. Cuddapah, A.B. Fleming, J. Birch, K. Cui, R.J. White, and K. Zhao Pol II and its associated epigenetic marks are present at Pol III-transcribed noncoding RNA genes Nat. Struct. Mol. Biol. 17 2010 629 634
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 629-634
-
-
Barski, A.1
Chepelev, I.2
Liko, D.3
Cuddapah, S.4
Fleming, A.B.5
Birch, J.6
Cui, K.7
White, R.J.8
Zhao, K.9
-
10
-
-
84866867319
-
H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions
-
M. Ku, J.D. Jaffe, R.P. Koche, E. Rheinbay, M. Endoh, H. Koseki, S.A. Carr, and B.E. Bernstein H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions Genome Biol. 13 2012 R85
-
(2012)
Genome Biol.
, vol.13
, pp. 85
-
-
Ku, M.1
Jaffe, J.D.2
Koche, R.P.3
Rheinbay, E.4
Endoh, M.5
Koseki, H.6
Carr, S.A.7
Bernstein, B.E.8
-
11
-
-
77649099092
-
Distinct factors control histone variant H3.3 localization at specific genomic regions
-
A.D. Goldberg, L.A. Banaszynski, K.M. Noh, P.W. Lewis, S.J. Elsaesser, S. Stadler, S. Dewell, M. Law, X. Guo, and X. Li Distinct factors control histone variant H3.3 localization at specific genomic regions Cell 140 2010 678 691
-
(2010)
Cell
, vol.140
, pp. 678-691
-
-
Goldberg, A.D.1
Banaszynski, L.A.2
Noh, K.M.3
Lewis, P.W.4
Elsaesser, S.J.5
Stadler, S.6
Dewell, S.7
Law, M.8
Guo, X.9
Li, X.10
-
12
-
-
1342343921
-
Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer
-
L.D. Attardi, A. de Vries, and T. Jacks Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer Oncogene 23 2004 973 980
-
(2004)
Oncogene
, vol.23
, pp. 973-980
-
-
Attardi, L.D.1
De Vries, A.2
Jacks, T.3
-
13
-
-
81855198087
-
All tangled up: How cells direct, manage and exploit topoisomerase function
-
S.M. Vos, E.M. Tretter, B.H. Schmidt, and J.M. Berger All tangled up: how cells direct, manage and exploit topoisomerase function Nat. Rev. Mol. Cell Biol. 12 2011 827 841
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 827-841
-
-
Vos, S.M.1
Tretter, E.M.2
Schmidt, B.H.3
Berger, J.M.4
-
14
-
-
0036674617
-
Live or let die: The cell's response to p53
-
K.H. Vousden, and X. Lu Live or let die: the cell's response to p53 Nat. Rev. Cancer 2 2002 594 604
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
15
-
-
37349055876
-
TP53 mutations and survival in squamous-cell carcinoma of the head and neck
-
M.L. Poeta, J. Manola, M.A. Goldwasser, A. Forastiere, N. Benoit, J.A. Califano, J.A. Ridge, J. Goodwin, D. Kenady, and J. Saunders TP53 mutations and survival in squamous-cell carcinoma of the head and neck N. Engl. J. Med. 357 2007 2552 2561
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 2552-2561
-
-
Poeta, M.L.1
Manola, J.2
Goldwasser, M.A.3
Forastiere, A.4
Benoit, N.5
Califano, J.A.6
Ridge, J.A.7
Goodwin, J.8
Kenady, D.9
Saunders, J.10
-
16
-
-
80052177544
-
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
-
N. Agrawal, M.J. Frederick, C.R. Pickering, C. Bettegowda, K. Chang, R.J. Li, C. Fakhry, T.X. Xie, J. Zhang, and J. Wang Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1 Science 333 2011 1154 1157
-
(2011)
Science
, vol.333
, pp. 1154-1157
-
-
Agrawal, N.1
Frederick, M.J.2
Pickering, C.R.3
Bettegowda, C.4
Chang, K.5
Li, R.J.6
Fakhry, C.7
Xie, T.X.8
Zhang, J.9
Wang, J.10
-
17
-
-
84862124987
-
P53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer
-
J.G. Jackson, V. Pant, Q. Li, L.L. Chang, A. Quintás-Cardama, D. Garza, O. Tavana, P. Yang, T. Manshouri, and Y. Li p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer Cancer Cell 21 2012 793 806
-
(2012)
Cancer Cell
, vol.21
, pp. 793-806
-
-
Jackson, J.G.1
Pant, V.2
Li, Q.3
Chang, L.L.4
Quintás-Cardama, A.5
Garza, D.6
Tavana, O.7
Yang, P.8
Manshouri, T.9
Li, Y.10
-
18
-
-
69249240178
-
The combined status of ATM and p53 link tumor development with therapeutic response
-
H. Jiang, H.C. Reinhardt, J. Bartkova, J. Tommiska, C. Blomqvist, H. Nevanlinna, J. Bartek, M.B. Yaffe, and M.T. Hemann The combined status of ATM and p53 link tumor development with therapeutic response Genes Dev. 23 2009 1895 1909
-
(2009)
Genes Dev.
, vol.23
, pp. 1895-1909
-
-
Jiang, H.1
Reinhardt, H.C.2
Bartkova, J.3
Tommiska, J.4
Blomqvist, C.5
Nevanlinna, H.6
Bartek, J.7
Yaffe, M.B.8
Hemann, M.T.9
-
19
-
-
11144234525
-
Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species
-
E.U. Kurz, P. Douglas, and S.P. Lees-Miller Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species J. Biol. Chem. 279 2004 53272 53281
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 53272-53281
-
-
Kurz, E.U.1
Douglas, P.2
Lees-Miller, S.P.3
-
20
-
-
84861701969
-
EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours
-
O. Bornachea, M. Santos, A.B. Martínez-Cruz, R. García-Escudero, M. Dueñas, C. Costa, C. Segrelles, C. Lorz, A. Buitrago, and C. Saiz-Ladera EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours Sci. Rep. 2 2012 434
-
(2012)
Sci. Rep.
, vol.2
, pp. 434
-
-
Bornachea, O.1
Santos, M.2
Martínez-Cruz, A.B.3
García-Escudero, R.4
Dueñas, M.5
Costa, C.6
Segrelles, C.7
Lorz, C.8
Buitrago, A.9
Saiz-Ladera, C.10
-
21
-
-
79960600521
-
P53 binding to nucleosomes within the p21 promoter in vivo leads to nucleosome loss and transcriptional activation
-
O. Laptenko, R. Beckerman, E. Freulich, and C. Prives p53 binding to nucleosomes within the p21 promoter in vivo leads to nucleosome loss and transcriptional activation Proc. Natl. Acad. Sci. USA 108 2011 10385 10390
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 10385-10390
-
-
Laptenko, O.1
Beckerman, R.2
Freulich, E.3
Prives, C.4
-
22
-
-
33745823159
-
The ATM-mediated DNA-damage response: Taking shape
-
Y. Shiloh The ATM-mediated DNA-damage response: taking shape Trends Biochem. Sci. 31 2006 402 410
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 402-410
-
-
Shiloh, Y.1
-
23
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
C.E. Canman, D.S. Lim, K.A. Cimprich, Y. Taya, K. Tamai, K. Sakaguchi, E. Appella, M.B. Kastan, and J.D. Siliciano Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 Science 281 1998 1677 1679
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Siliciano, J.D.9
-
24
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
S. Burma, B.P. Chen, M. Murphy, A. Kurimasa, and D.J. Chen ATM phosphorylates histone H2AX in response to DNA double-strand breaks J. Biol. Chem. 276 2001 42462 42467
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.J.5
-
25
-
-
57149136324
-
GammaH2AX and cancer
-
W.M. Bonner, C.E. Redon, J.S. Dickey, A.J. Nakamura, O.A. Sedelnikova, S. Solier, and Y. Pommier GammaH2AX and cancer Nat. Rev. Cancer 8 2008 957 967
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 957-967
-
-
Bonner, W.M.1
Redon, C.E.2
Dickey, J.S.3
Nakamura, A.J.4
Sedelnikova, O.A.5
Solier, S.6
Pommier, Y.7
-
26
-
-
34248576179
-
Elimination of radiation-induced gamma-H2AX foci in mammalian nucleus can occur by histone exchange
-
M. Svetlova, L. Solovjeva, K. Nishi, I. Nazarov, J. Siino, and N. Tomilin Elimination of radiation-induced gamma-H2AX foci in mammalian nucleus can occur by histone exchange Biochem. Biophys. Res. Commun. 358 2007 650 654
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.358
, pp. 650-654
-
-
Svetlova, M.1
Solovjeva, L.2
Nishi, K.3
Nazarov, I.4
Siino, J.5
Tomilin, N.6
-
27
-
-
0036402522
-
Photobleaching of GFP-labeled H2AX in chromatin: H2AX has low diffusional mobility in the nucleus
-
J.S. Siino, I.B. Nazarov, M.P. Svetlova, L.V. Solovjeva, R.H. Adamson, I.A. Zalenskaya, P.M. Yau, E.M. Bradbury, and N.V. Tomilin Photobleaching of GFP-labeled H2AX in chromatin: H2AX has low diffusional mobility in the nucleus Biochem. Biophys. Res. Commun. 297 2002 1318 1323
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.297
, pp. 1318-1323
-
-
Siino, J.S.1
Nazarov, I.B.2
Svetlova, M.P.3
Solovjeva, L.V.4
Adamson, R.H.5
Zalenskaya, I.A.6
Yau, P.M.7
Bradbury, E.M.8
Tomilin, N.V.9
-
28
-
-
77954187741
-
DNA topoisomerases and their poisoning by anticancer and antibacterial drugs
-
Y. Pommier, E. Leo, H. Zhang, and C. Marchand DNA topoisomerases and their poisoning by anticancer and antibacterial drugs Chem. Biol. 17 2010 421 433
-
(2010)
Chem. Biol.
, vol.17
, pp. 421-433
-
-
Pommier, Y.1
Leo, E.2
Zhang, H.3
Marchand, C.4
-
29
-
-
0025298540
-
Antagonistic effect of aclarubicin on the cytotoxicity of etoposide and 4′-(9-acridinylamino)methanesulfon-m-anisidide in human small cell lung cancer cell lines and on topoisomerase II-mediated DNA cleavage
-
P.B. Jensen, B.S. Sørensen, E.J. Demant, M. Sehested, P.S. Jensen, L. Vindeløv, and H.H. Hansen Antagonistic effect of aclarubicin on the cytotoxicity of etoposide and 4′-(9-acridinylamino)methanesulfon-m- anisidide in human small cell lung cancer cell lines and on topoisomerase II-mediated DNA cleavage Cancer Res. 50 1990 3311 3316
-
(1990)
Cancer Res.
, vol.50
, pp. 3311-3316
-
-
Jensen, P.B.1
Sørensen, B.S.2
Demant, E.J.3
Sehested, M.4
Jensen, P.S.5
Vindeløv, L.6
Hansen, H.H.7
-
30
-
-
80051805781
-
How are nucleosomes disrupted during transcription elongation?
-
J. Zlatanova, and J.M. Victor How are nucleosomes disrupted during transcription elongation? HFSP J. 3 2009 373 378
-
(2009)
HFSP J.
, vol.3
, pp. 373-378
-
-
Zlatanova, J.1
Victor, J.M.2
-
31
-
-
0023433855
-
Supercoiling of the DNA template during transcription
-
L.F. Liu, and J.C. Wang Supercoiling of the DNA template during transcription Proc. Natl. Acad. Sci. USA 84 1987 7024 7027
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 7024-7027
-
-
Liu, L.F.1
Wang, J.C.2
-
32
-
-
0024279845
-
Transcription generates positively and negatively supercoiled domains in the template
-
H.Y. Wu, S.H. Shyy, J.C. Wang, and L.F. Liu Transcription generates positively and negatively supercoiled domains in the template Cell 53 1988 433 440
-
(1988)
Cell
, vol.53
, pp. 433-440
-
-
Wu, H.Y.1
Shyy, S.H.2
Wang, J.C.3
Liu, L.F.4
-
33
-
-
84864619205
-
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
-
ALT Starr Cancer Consortium
-
C.A. Lovejoy, W. Li, S. Reisenweber, S. Thongthip, J. Bruno, T. de Lange, S. De, J.H. Petrini, P.A. Sung, M. Jasin ALT Starr Cancer Consortium Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway PLoS Genet. 8 2012 e1002772
-
(2012)
PLoS Genet.
, vol.8
, pp. 1002772
-
-
Lovejoy, C.A.1
Li, W.2
Reisenweber, S.3
Thongthip, S.4
Bruno, J.5
De Lange, T.6
De, S.7
Petrini, J.H.8
Sung, P.A.9
Jasin, M.10
-
34
-
-
80455144217
-
Embolization of hepatocellular carcinoma with drug-eluting beads: Doxorubicin tissue concentration and distribution in patient liver explants
-
J. Namur, S.J. Citron, M.T. Sellers, M.H. Dupuis, M. Wassef, M. Manfait, and A. Laurent Embolization of hepatocellular carcinoma with drug-eluting beads: doxorubicin tissue concentration and distribution in patient liver explants J. Hepatol. 55 2011 1332 1338
-
(2011)
J. Hepatol.
, vol.55
, pp. 1332-1338
-
-
Namur, J.1
Citron, S.J.2
Sellers, M.T.3
Dupuis, M.H.4
Wassef, M.5
Manfait, M.6
Laurent, A.7
-
35
-
-
2542622944
-
Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test
-
M. Lehmann, Kde.S. Vilar, A. Franco, M.L. Reguly, and H.H. Rodrigues de Andrade Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test Environ. Mol. Mutagen. 43 2004 250 257
-
(2004)
Environ. Mol. Mutagen.
, vol.43
, pp. 250-257
-
-
Lehmann, M.1
Vilar, Kde.S.2
Franco, A.3
Reguly, M.L.4
Rodrigues De Andrade, H.H.5
-
36
-
-
34447251894
-
Normalization and experimental design for ChIP-chip data
-
S. Peng, A.A. Alekseyenko, E. Larschan, M.I. Kuroda, and P.J. Park Normalization and experimental design for ChIP-chip data BMC Bioinformatics 8 2007 219
-
(2007)
BMC Bioinformatics
, vol.8
, pp. 219
-
-
Peng, S.1
Alekseyenko, A.A.2
Larschan, E.3
Kuroda, M.I.4
Park, P.J.5
-
37
-
-
78649281582
-
Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis
-
M.L. Conerly, S.S. Teves, D. Diolaiti, M. Ulrich, R.N. Eisenman, and S. Henikoff Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis Genome Res. 20 2010 1383 1390
-
(2010)
Genome Res.
, vol.20
, pp. 1383-1390
-
-
Conerly, M.L.1
Teves, S.S.2
Diolaiti, D.3
Ulrich, M.4
Eisenman, R.N.5
Henikoff, S.6
-
38
-
-
84864494098
-
GeneCodis3: A non-redundant and modular enrichment analysis tool for functional genomics
-
WEB SERVER ISSUE
-
D. Tabas-Madrid, R. Nogales-Cadenas, and A. Pascual-Montano GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomics Nucleic Acids Res. 40 Web Server issue 2012 W478 W483
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Tabas-Madrid, D.1
Nogales-Cadenas, R.2
Pascual-Montano, A.3
-
39
-
-
33847205295
-
GENECODIS: A web-based tool for finding significant concurrent annotations in gene lists
-
P. Carmona-Saez, M. Chagoyen, F. Tirado, J.M. Carazo, and A. Pascual-Montano GENECODIS: a web-based tool for finding significant concurrent annotations in gene lists Genome Biol. 8 2007 R3
-
(2007)
Genome Biol.
, vol.8
, pp. 3
-
-
Carmona-Saez, P.1
Chagoyen, M.2
Tirado, F.3
Carazo, J.M.4
Pascual-Montano, A.5
-
40
-
-
67849088720
-
GeneCodis: Interpreting gene lists through enrichment analysis and integration of diverse biological information
-
WEB SERVER ISSUE
-
R. Nogales-Cadenas, P. Carmona-Saez, M. Vazquez, C. Vicente, X. Yang, F. Tirado, J.M. Carazo, and A. Pascual-Montano GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information Nucleic Acids Res. 37 Web Server issue 2009 W317 W322
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Nogales-Cadenas, R.1
Carmona-Saez, P.2
Vazquez, M.3
Vicente, C.4
Yang, X.5
Tirado, F.6
Carazo, J.M.7
Pascual-Montano, A.8
|