Activation of DNA damage response pathways as a consequence of anthracycline-DNA adduct formation

Biochemical Pharmacology

Volumn 83, Issue 12, 2012, Pages 1602-1612

  Forrest, Robert A ^a   Swift, Lonnie P ^a   Rephaeli, Ada ^b   Nudelman, Abraham ^c   Kimura, Ken Ichi ^d   Phillips, Don R ^a   Cutts, Suzanne M ^a  

^a LA TROBE UNIVERSITY   (Australia)

^b TEL AVIV UNIVERSITY   (Israel)

^c BAR ILAN UNIVERSITY   (Israel)

^d IWATE UNIVERSITY   (Japan)

Author keywords

ATM; ATR; DNA damage; Doxorubicin; Formaldehyde

Indexed keywords

ATM PROTEIN; ATR PROTEIN; DNA; DOXORUBICIN; HISTONE H2AX; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PIVALOYLOXYMETHYL BUTYRATE; PROTEIN P53; SERINE;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG POTENTIATION; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANTIBIOTICS, ANTINEOPLASTIC; BLOTTING, WESTERN; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA; DNA ADDUCTS; DNA DAMAGE; DNA-BINDING PROTEINS; DOXORUBICIN; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84860211968     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.02.026     Document Type: Article

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