메뉴 건너뛰기




Volumn 306, Issue 1, 2014, Pages

Enhanced insulin secretion responsiveness and islet adrenergic desensitization after chronic norepinephrine suppression is discontinued in fetal sheep

Author keywords

Adrenergic receptor; Catecholamines; Intrauterine growth restriction; Uncoupling protein 2; cell

Indexed keywords

ALPHA 1D ADRENERGIC RECEPTOR; ALPHA 2A ADRENERGIC RECEPTOR; ALPHA 2C ADRENERGIC RECEPTOR; ARGININE; BETA 1 ADRENERGIC RECEPTOR; GLUCOSE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INSULIN; MESSENGER RNA; NORADRENALIN; UNCOUPLING PROTEIN 2;

EID: 84891507679     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00517.2013     Document Type: Article
Times cited : (40)

References (57)
  • 1
    • 0031894158 scopus 로고    scopus 로고
    • Maturation of glucose-stimulated insulin secretion in fetal sheep
    • Aldoretta PW, Carver TD, Hay WW Jr. Maturation of glucose-stimulated insulin secretion in fetal sheep. Biol Neonate 73: 375-386, 1998.
    • (1998) Biol Neonate , vol.73 , pp. 375-386
    • Aldoretta, P.W.1    Carver, T.D.2    Hay Jr., W.W.3
  • 2
    • 0023911193 scopus 로고
    • Adenosine 5-triphosphate-sensitive potassium channels
    • Ashcroft FM. Adenosine 5-triphosphate-sensitive potassium channels. Annu Rev Neurosci 11: 97-118, 1988.
    • (1988) Annu Rev Neurosci , vol.11 , pp. 97-118
    • Ashcroft, F.M.1
  • 3
    • 0031775878 scopus 로고    scopus 로고
    • Catecholamines inhibit growth in fetal sheep in the absence of hypoxemia
    • Bassett JM, Hanson C. Catecholamines inhibit growth in fetal sheep in the absence of hypoxemia. Am J Physiol Regul Integr Comp Physiol 274: R1536-R1545, 1998.
    • (1998) Am J Physiol Regul Integr Comp Physiol , vol.274
    • Bassett, J.M.1    Hanson, C.2
  • 4
    • 0023102686 scopus 로고
    • Some aspects of placental function in chronically heat-stressed ewes
    • Bell AW, Wilkening RB, Meschia G. Some aspects of placental function in chronically heat-stressed ewes. J Dev Physiol 9: 17-29, 1987.
    • (1987) J Dev Physiol , vol.9 , pp. 17-29
    • Bell, A.W.1    Wilkening, R.B.2    Meschia, G.3
  • 5
    • 0025340439 scopus 로고
    • Regulation of G protein-coupled receptors by agonist-dependent phosphorylation
    • Benovic JL, Onorato JJ, Caron MG, Lefkowitz RJ. Regulation of G protein-coupled receptors by agonist-dependent phosphorylation. Soc Gen Physiol Ser 45: 87-103, 1990.
    • (1990) Soc Gen Physiol Ser , vol.45 , pp. 87-103
    • Benovic, J.L.1    Onorato, J.J.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 6
    • 77955509318 scopus 로고    scopus 로고
    • Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC), Hansen T, Pedersen O. Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people
    • Boesgaard TW, Grarup N, Jørgensen T, Borch-Johnsen K; Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC), Hansen T, Pedersen O. Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people. Diabetologia 53: 1647-1655, 2010.
    • (2010) Diabetologia , vol.53 , pp. 1647-1655
    • Boesgaard, T.W.1    Grarup, N.2    Jørgensen, T.3    Borch-Johnsen, K.4
  • 7
    • 0020744174 scopus 로고
    • Blood volume and its measurement in the chronically catheterized sheep fetus
    • Brace RA. Blood volume and its measurement in the chronically catheterized sheep fetus. Am J Physiol Heart Circ Physiol 244: H487-H494, 1983.
    • (1983) Am J Physiol Heart Circ Physiol , vol.244
    • Brace, R.A.1
  • 8
    • 0037181143 scopus 로고    scopus 로고
    • Glucose induces and leptin decreases expression of uncoupling protein-2 mRNA in human islets
    • Brown JE, Thomas S, Digby JE, Dunmore SJ. Glucose induces and leptin decreases expression of uncoupling protein-2 mRNA in human islets. FEBS Lett 513: 189-192, 2002.
    • (2002) FEBS Lett , vol.513 , pp. 189-192
    • Brown, J.E.1    Thomas, S.2    Digby, J.E.3    Dunmore, S.J.4
  • 9
    • 0031020519 scopus 로고    scopus 로고
    • The contribution of transporter-dependent uptake to fetal catecholamine clearance
    • Bzoskie L, Blount L, Kashiwai K, Humme J, Padbury JF. The contribution of transporter-dependent uptake to fetal catecholamine clearance. Biol Neonate 71: 102-110, 1997.
    • (1997) Biol Neonate , vol.71 , pp. 102-110
    • Bzoskie, L.1    Blount, L.2    Kashiwai, K.3    Humme, J.4    Padbury, J.F.5
  • 12
    • 77956748300 scopus 로고    scopus 로고
    • β2-Adrenergic receptor desensitization in perirenal adipose tissue in fetuses and lambs with placental insufficiency-induced intrauterine growth restriction
    • Chen X, Fahy AL, Green AS, Anderson MJ, Rhoads RP, Limesand SW. β2-Adrenergic receptor desensitization in perirenal adipose tissue in fetuses and lambs with placental insufficiency-induced intrauterine growth restriction. J Physiol 588: 3539-3549, 2010.
    • (2010) J Physiol , vol.588 , pp. 3539-3549
    • Chen, X.1    Fahy, A.L.2    Green, A.S.3    Anderson, M.J.4    Rhoads, R.P.5    Limesand, S.W.6
  • 13
    • 84862016395 scopus 로고    scopus 로고
    • Insulin-like growth factor and fibroblast growth factor expression profiles in growth-restricted fetal sheep pancreas
    • Chen X, Rozance PJ, Hay WW Jr, Limesand SW. Insulin-like growth factor and fibroblast growth factor expression profiles in growth-restricted fetal sheep pancreas. Exp Biol Med (Maywood) 237: 524-529, 2012.
    • (2012) Exp Biol Med (Maywood) , vol.237 , pp. 524-529
    • Chen, X.1    Rozance, P.J.2    Hay Jr., W.W.3    Limesand, S.W.4
  • 14
    • 0025973966 scopus 로고
    • Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression
    • Collins S, Caron MG, Lefkowitz RJ. Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression. Annu Rev Physiol 53: 497-508, 1991.
    • (1991) Annu Rev Physiol , vol.53 , pp. 497-508
    • Collins, S.1    Caron, M.G.2    Lefkowitz, R.J.3
  • 15
    • 84855821583 scopus 로고    scopus 로고
    • UCP2 mRNA expression is dependent on glucose metabolism in pancreatic islets
    • Dalgaard LT. UCP2 mRNA expression is dependent on glucose metabolism in pancreatic islets. Biochem Biophys Res Commun 417: 495-500, 2012.
    • (2012) Biochem Biophys Res Commun , vol.417 , pp. 495-500
    • Dalgaard, L.T.1
  • 18
    • 2942544589 scopus 로고    scopus 로고
    • Endocrine mechanisms of intrauterine programming
    • Fowden AL, Forhead AJ. Endocrine mechanisms of intrauterine programming. Reproduction 127: 515-526, 2004.
    • (2004) Reproduction , vol.127 , pp. 515-526
    • Fowden, A.L.1    Forhead, A.J.2
  • 19
    • 2442650287 scopus 로고    scopus 로고
    • Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta-and delta-cells within intact islets of Langerhans
    • Gopel S, Zhang Q, Eliasson L, Ma XS, Galvanovskis J, Kanno T, Salehi A, Rorsman P. Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta-and delta-cells within intact islets of Langerhans. J Physiol 556: 711-726, 2004.
    • (2004) J Physiol , vol.556 , pp. 711-726
    • Gopel, S.1    Zhang, Q.2    Eliasson, L.3    Ma, X.S.4    Galvanovskis, J.5    Kanno, T.6    Salehi, A.7    Rorsman, P.8
  • 20
    • 84863269955 scopus 로고    scopus 로고
    • Chronic pulsatile hyperglycemia reduces insulin secretion and increases accumulation of reactive oxygen species in fetal sheep islets
    • Green AS, Chen X, Macko AR, Anderson MJ, Kelly AC, Hart NJ, Lynch RM, Limesand SW. Chronic pulsatile hyperglycemia reduces insulin secretion and increases accumulation of reactive oxygen species in fetal sheep islets. J Endocrinol 212: 327-342, 2012.
    • (2012) J Endocrinol , vol.212 , pp. 327-342
    • Green, A.S.1    Chen, X.2    Macko, A.R.3    Anderson, M.J.4    Kelly, A.C.5    Hart, N.J.6    Lynch, R.M.7    Limesand, S.W.8
  • 22
    • 77952575139 scopus 로고    scopus 로고
    • Consequences of a compromised intrauterine environment on islet function
    • Green AS, Rozance PJ, Limesand SW. Consequences of a compromised intrauterine environment on islet function. J Endocrinol 205: 211-224, 2010.
    • (2010) J Endocrinol , vol.205 , pp. 211-224
    • Green, A.S.1    Rozance, P.J.2    Limesand, S.W.3
  • 25
    • 15744379018 scopus 로고    scopus 로고
    • Oxidative stress-mediated, posttranslational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells
    • Harmon JS, Stein R, Robertson RP. Oxidative stress-mediated, posttranslational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells. J Biol Chem 280: 11107-11113, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 11107-11113
    • Harmon, J.S.1    Stein, R.2    Robertson, R.P.3
  • 27
    • 0036227764 scopus 로고    scopus 로고
    • Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight
    • Jensen CB, Storgaard H, Dela F, Holst JJ, Madsbad S, Vaag AA. Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight. Diabetes 51: 1271-1280, 2002.
    • (2002) Diabetes , vol.51 , pp. 1271-1280
    • Jensen, C.B.1    Storgaard, H.2    Dela, F.3    Holst, J.J.4    Madsbad, S.5    Vaag, A.A.6
  • 28
    • 0036306096 scopus 로고    scopus 로고
    • Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U. S
    • American Diabetes Association GENNID Study Group
    • Jensen CC, Cnop M, Hull RL, Fujimoto WY, Kahn SE; American Diabetes Association GENNID Study Group. Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S. Diabetes 51: 2170-2178, 2002.
    • (2002) Diabetes , vol.51 , pp. 2170-2178
    • Jensen, C.C.1    Cnop, M.2    Hull, R.L.3    Fujimoto, W.Y.4    Kahn, S.E.5
  • 30
    • 0023580244 scopus 로고
    • Alpha 2-adrenoceptor stimulation affects total glucose utilization in isolated islets of Langerhans
    • Laychock SG. Alpha 2-adrenoceptor stimulation affects total glucose utilization in isolated islets of Langerhans. Mol Pharmacol 32: 241-248, 1987.
    • (1987) Mol Pharmacol , vol.32 , pp. 241-248
    • Laychock, S.G.1
  • 31
    • 0023255689 scopus 로고
    • Alpha 2-adrenergic inhibition of pancreatic islet glucose utilization is mediated by an inhibitory guanine nucleotide regulatory protein
    • Laychock SG, Bilgin S. Alpha 2-adrenergic inhibition of pancreatic islet glucose utilization is mediated by an inhibitory guanine nucleotide regulatory protein. FEBS Lett 218: 7-10, 1987.
    • (1987) FEBS Lett , vol.218 , pp. 7-10
    • Laychock, S.G.1    Bilgin, S.2
  • 32
    • 77949843950 scopus 로고    scopus 로고
    • Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction
    • Leos RA, Anderson MJ, Chen X, Pugmire J, Anderson KA, Limesand SW. Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction. Am J Physiol Endocrinol Metab 298: E770-E778, 2010.
    • (2010) Am J Physiol Endocrinol Metab , vol.298
    • Leos, R.A.1    Anderson, M.J.2    Chen, X.3    Pugmire, J.4    Anderson, K.A.5    Limesand, S.W.6
  • 33
    • 0037440658 scopus 로고    scopus 로고
    • Adaptation of ovine fetal pancreatic insulin secretion to chronic hypoglycaemia and euglycaemic correction
    • Limesand SW, Hay WW Jr. Adaptation of ovine fetal pancreatic insulin secretion to chronic hypoglycaemia and euglycaemic correction. J Physiol 547: 95-105, 2003.
    • (2003) J Physiol , vol.547 , pp. 95-105
    • Limesand, S.W.1    Hay Jr., W.W.2
  • 34
    • 17844371675 scopus 로고    scopus 로고
    • Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction
    • Limesand SW, Jensen J, Hutton JC, Hay WW Jr. Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol 288: R1297-R1305, 2005.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Limesand, S.W.1    Jensen, J.2    Hutton, J.C.3    Hay Jr., W.W.4
  • 36
    • 32644433563 scopus 로고    scopus 로고
    • Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction
    • Limesand SW, Rozance PJ, Zerbe GO, Hutton JC, Hay WW Jr. Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction. Endocrinology 147: 1488-1497, 2006.
    • (2006) Endocrinology , vol.147 , pp. 1488-1497
    • Limesand, S.W.1    Rozance, P.J.2    Zerbe, G.O.3    Hutton, J.C.4    Hay Jr., W.W.5
  • 37
    • 84883323111 scopus 로고    scopus 로고
    • Elevated plasma norepinephrine inhibits insulin secretion, but adrenergic blockade reveals enhanced β-cell responsiveness in an ovine model of placental insufficiency at 0.7 of gestation
    • Macko AR, Yates DT, Chen X, Green AS, Kelly AC, Brown LD, Limesand SW. Elevated plasma norepinephrine inhibits insulin secretion, but adrenergic blockade reveals enhanced β-cell responsiveness in an ovine model of placental insufficiency at 0.7 of gestation. J Dev Origin Health Dis 4: 402-410, 2013.
    • (2013) J Dev Origin Health Dis , vol.4 , pp. 402-410
    • Macko, A.R.1    Yates, D.T.2    Chen, X.3    Green, A.S.4    Kelly, A.C.5    Brown, L.D.6    Limesand, S.W.7
  • 38
    • 20644439086 scopus 로고    scopus 로고
    • Ovine fetal metabolism during norepinephrine infusion
    • Milley JR. Ovine fetal metabolism during norepinephrine infusion. Am J Physiol Endocrinol Metab 273: E336-E347, 1997.
    • (1997) Am J Physiol Endocrinol Metab , vol.273
    • Milley, J.R.1
  • 40
    • 0038192201 scopus 로고    scopus 로고
    • Is birth weight related to later glucose and insulin metabolism?-A systematic review
    • Newsome CA, Shiell AW, Fall CH, Phillips DI, Shier R, Law CM. Is birth weight related to later glucose and insulin metabolism?-A systematic review. Diabet Med 20: 339-348, 2003.
    • (2003) Diabet Med , vol.20 , pp. 339-348
    • Newsome, C.A.1    Shiell, A.W.2    Fall, C.H.3    Phillips, D.I.4    Shier, R.5    Law, C.M.6
  • 41
    • 0025183588 scopus 로고
    • Effects of fetal intravenous glucose challenge in normal and growth retarded fetuses
    • Nicolini U, Hubinont C, Santolaya J, Fisk NM, Rodeck CH. Effects of fetal intravenous glucose challenge in normal and growth retarded fetuses. Horm Metab Res 22: 426-430, 1990.
    • (1990) Horm Metab Res , vol.22 , pp. 426-430
    • Nicolini, U.1    Hubinont, C.2    Santolaya, J.3    Fisk, N.M.4    Rodeck, C.H.5
  • 42
    • 0027384997 scopus 로고
    • IPF1, a homeodomain-containing transactivator of the insulin gene
    • Ohlsson H, Karlsson K, Edlund T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 12: 4251-4259, 1993.
    • (1993) EMBO J , vol.12 , pp. 4251-4259
    • Ohlsson, H.1    Karlsson, K.2    Edlund, T.3
  • 43
    • 0022480304 scopus 로고
    • Metabolic clearance and plasma appearance rates of catecholamines in preterm and term fetal sheep
    • Padbury JF, Ludlow JK, Humme JA, Agata Y. Metabolic clearance and plasma appearance rates of catecholamines in preterm and term fetal sheep. Pediatr Res 20: 992-995, 1986.
    • (1986) Pediatr Res , vol.20 , pp. 992-995
    • Padbury, J.F.1    Ludlow, J.K.2    Humme, J.A.3    Agata, Y.4
  • 44
    • 0036724133 scopus 로고    scopus 로고
    • Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition
    • Patane G, Anello M, Piro S, Vigneri R, Purrello F, Rabuazzo AM. Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition. Diabetes 51: 2749-2756, 2002.
    • (2002) Diabetes , vol.51 , pp. 2749-2756
    • Patane, G.1    Anello, M.2    Piro, S.3    Vigneri, R.4    Purrello, F.5    Rabuazzo, A.M.6
  • 45
    • 0142247456 scopus 로고    scopus 로고
    • Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice
    • Peterhoff M, Sieg A, Brede M, Chao CM, Hein L, Ullrich S. Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice. Eur J Endocrinol 149: 343-350, 2003.
    • (2003) Eur J Endocrinol , vol.149 , pp. 343-350
    • Peterhoff, M.1    Sieg, A.2    Brede, M.3    Chao, C.M.4    Hein, L.5    Ullrich, S.6
  • 46
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45, 2001.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 47
    • 0012746562 scopus 로고    scopus 로고
    • Placental development in normal and compromised pregnancies-a review
    • Regnault TR, Galan HL, Parker TA, Anthony RV. Placental development in normal and compromised pregnancies-a review. Placenta 23, Suppl A: S119-S129, 2002.
    • (2002) Placenta , vol.23 , Issue.SUPPL. A
    • Regnault, T.R.1    Galan, H.L.2    Parker, T.A.3    Anthony, R.V.4
  • 50
    • 33745814724 scopus 로고    scopus 로고
    • Decreased nutrient-stimulated insulin secretion in chronically hypoglycemic late-gestation fetal sheep is due to an intrinsic islet defect
    • Rozance PJ, Limesand SW, Hay WW Jr. Decreased nutrient-stimulated insulin secretion in chronically hypoglycemic late-gestation fetal sheep is due to an intrinsic islet defect. Am J Physiol Endocrinol Metab 291: E404-E411, 2006.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Rozance, P.J.1    Limesand, S.W.2    Hay Jr., W.W.3
  • 51
    • 0030474003 scopus 로고    scopus 로고
    • Mechanisms of inhibition of insulin release
    • Sharp GW. Mechanisms of inhibition of insulin release. Am J Physiol Cell Physiol 271: C1781-C1799, 1996.
    • (1996) Am J Physiol Cell Physiol , vol.271
    • Sharp, G.W.1
  • 52
    • 6944237771 scopus 로고    scopus 로고
    • Desensitization of the inhibitory effect of norepinephrine on insulin secretion from pancreatic islets of exercise-trained rats
    • Urano Y, Sakurai T, Ueda H, Ogasawara J, Takei M, Izawa T. Desensitization of the inhibitory effect of norepinephrine on insulin secretion from pancreatic islets of exercise-trained rats. Metabolism 53: 1424-1432, 2004.
    • (2004) Metabolism , vol.53 , pp. 1424-1432
    • Urano, Y.1    Sakurai, T.2    Ueda, H.3    Ogasawara, J.4    Takei, M.5    Izawa, T.6
  • 55
    • 84863788721 scopus 로고    scopus 로고
    • Leucine stimulates insulin secretion via down-regulation of surface expression of adrenergic alpha2A receptor through the mTOR (mammalian target of rapamycin) pathway: Implication in new-onset diabetes in renal transplantation
    • Yang J, Dolinger M, Ritaccio G, Mazurkiewicz J, Conti D, Zhu X, Huang Y. Leucine stimulates insulin secretion via down-regulation of surface expression of adrenergic alpha2A receptor through the mTOR (mammalian target of rapamycin) pathway: implication in new-onset diabetes in renal transplantation. J Biol Chem 287: 24795-24806, 2012.
    • (2012) J Biol Chem , vol.287 , pp. 24795-24806
    • Yang, J.1    Dolinger, M.2    Ritaccio, G.3    Mazurkiewicz, J.4    Conti, D.5    Zhu, X.6    Huang, Y.7
  • 56
    • 84868150026 scopus 로고    scopus 로고
    • Hypoxaemia-induced catecholamine secretion from adrenal chromaffin cells inhibits glucose-stimulated hyperinsulinaemia in fetal sheep
    • Yates DT, Macko AR, Chen X, Green AS, Kelly AC, Anderson MJ, Fowden AL, Limesand SW. Hypoxaemia-induced catecholamine secretion from adrenal chromaffin cells inhibits glucose-stimulated hyperinsulinaemia in fetal sheep. J Physiol 590: 5439-5447, 2012.
    • (2012) J Physiol , vol.590 , pp. 5439-5447
    • Yates, D.T.1    Macko, A.R.2    Chen, X.3    Green, A.S.4    Kelly, A.C.5    Anderson, M.J.6    Fowden, A.L.7    Limesand, S.W.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.