메뉴 건너뛰기




Volumn 304, Issue 5, 2013, Pages

Reductions in insulin concentrations and β-cell mass precede growth restriction in sheep fetuses with placental insufficiency

Author keywords

Glucose; Intrauterine growth restriction; Norepinephrine; Oxygen; Pancreas

Indexed keywords

GLUCOSE; INSULIN; NORADRENALIN; OXYGEN;

EID: 84874535622     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00435.2012     Document Type: Article
Times cited : (54)

References (52)
  • 1
    • 0031894158 scopus 로고    scopus 로고
    • Maturation of glucose-stimulated insulin secretion in fetal sheep
    • Aldoretta PW, Carver TD, Hay WW Jr. Maturation of glucose-stimulated insulin secretion in fetal sheep. Biol Neonate 73: 375-386, 1998.
    • (1998) Biol Neonate , vol.73 , pp. 375-386
    • Aldoretta, P.W.1    Carver, T.D.2    Hay Jr., W.W.3
  • 3
    • 43049176240 scopus 로고    scopus 로고
    • An animal model of placental insufficiency-induced intrauterine growth restriction
    • Barry JS, Rozance PJ, Anthony RV. An animal model of placental insufficiency-induced intrauterine growth restriction. Semin Perinatol 32: 225-230, 2008.
    • (2008) Semin Perinatol , vol.32 , pp. 225-230
    • Barry, J.S.1    Rozance, P.J.2    Anthony, R.V.3
  • 4
    • 0031775878 scopus 로고    scopus 로고
    • Catecholamines inhibit growth in fetal sheep in the absence of hypoxemia
    • Bassett JM, Hanson C. Catecholamines inhibit growth in fetal sheep in the absence of hypoxemia. Am J Physiol Regul Integr Comp Physiol 274: R1536-R1545, 1998.
    • (1998) Am J Physiol Regul Integr Comp Physiol , vol.274
    • Bassett, J.M.1    Hanson, C.2
  • 5
    • 0034080030 scopus 로고    scopus 로고
    • Prevention of hypoinsulinemia modifies catecholamine effects in fetal sheep
    • Bassett JM, Hanson C. Prevention of hypoinsulinemia modifies catecholamine effects in fetal sheep. Am J Physiol Regul Integr Comp Physiol 278: R1171-R1181, 2000.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.278
    • Bassett, J.M.1    Hanson, C.2
  • 6
    • 0023102686 scopus 로고
    • Some aspects of placental function in chronically heat-stressed ewes
    • Bell AW, Wilkening RB, Meschia G. Some aspects of placental function in chronically heat-stressed ewes. J Dev Physiol 9: 17-29, 1987.
    • (1987) J Dev Physiol , vol.9 , pp. 17-29
    • Bell, A.W.1    Wilkening, R.B.2    Meschia, G.3
  • 8
    • 84862016395 scopus 로고    scopus 로고
    • Insulin-like growth factor and fibroblast growth factor expression profiles in growth-restricted fetal sheep pancreas
    • Chen X, Rozance PJ, Hay WW Jr, Limesand SW. Insulin-like growth factor and fibroblast growth factor expression profiles in growth-restricted fetal sheep pancreas. Exp Biol Med 237: 524-529, 2012.
    • (2012) Exp Biol Med , vol.237 , pp. 524-529
    • Chen, X.1    Rozance, P.J.2    Hay Jr., W.W.3    Limesand, S.W.4
  • 9
    • 0025310140 scopus 로고
    • Fetal adrenal medulla catecholamine response to hypoxiadirect and neural components
    • Cheung CY. Fetal adrenal medulla catecholamine response to hypoxiadirect and neural components. Am J Physiol Regul Integr Comp Physiol 258: R1340-R1346, 1990.
    • (1990) Am J Physiol Regul Integr Comp Physiol , vol.258
    • Cheung, C.Y.1
  • 10
    • 70349778139 scopus 로고    scopus 로고
    • One process for pancreatic β-cell coalescence into islets involves an epithelial-mesenchymal transition
    • Cole L, Anderson MJ, Antin PB, Limesand SW. One process for pancreatic β-cell coalescence into islets involves an epithelial-mesenchymal transition. J Endocrinol 203: 19-31, 2009.
    • (2009) J Endocrinol , vol.203 , pp. 19-31
    • Cole, L.1    Anderson, M.J.2    Antin, P.B.3    Limesand, S.W.4
  • 11
    • 0002081804 scopus 로고    scopus 로고
    • Intrauterine growth restriction
    • In: edited by Creasy RK and Resnik R. Philadelphia, PA: Saunders
    • Creasy RK, Resnik R. Intrauterine growth restriction. In: Maternal-Fetal Medicine, edited by Creasy RK and Resnik R. Philadelphia, PA: Saunders, 1999, p. 569-584.
    • (1999) Maternal-Fetal Medicine , pp. 569-584
    • Creasy, R.K.1    Resnik, R.2
  • 12
    • 8644282099 scopus 로고    scopus 로고
    • Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction
    • de Vrijer B, Regnault TR, Wilkening RB, Meschia G, Battaglia FC. Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction. Am J Physiol Endocrinol Metab 287: E1114-E1124, 2004.
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • de Vrijer, B.1    Regnault, T.R.2    Wilkening, R.B.3    Meschia, G.4    Battaglia, F.C.5
  • 14
    • 0025312695 scopus 로고
    • Relation between maternal-to-fetal blood glucose gradient and uterine and umbilical Doppler blood flow measurements
    • Economides DL, Nicolaides KH, Campbell S. Relation between maternal-to-fetal blood glucose gradient and uterine and umbilical Doppler blood flow measurements. Br J Obstet Gynaecol 97: 543-544, 1990.
    • (1990) Br J Obstet Gynaecol , vol.97 , pp. 543-544
    • Economides, D.L.1    Nicolaides, K.H.2    Campbell, S.3
  • 16
    • 0023767624 scopus 로고
    • The effects of pancreatectomy on the rates of glucose utilization, oxidation and production in the sheep fetus
    • Fowden AL, Hay WW Jr. The effects of pancreatectomy on the rates of glucose utilization, oxidation and production in the sheep fetus. Q J Exp Physiol 73: 973-984, 1988.
    • (1988) Q J Exp Physiol , vol.73 , pp. 973-984
    • Fowden, A.L.1    Hay Jr., W.W.2
  • 17
    • 84863269955 scopus 로고    scopus 로고
    • Chronic pulsatile hyperglycemia reduces insulin secretion and increases accumulation of reactive oxygen species in fetal sheep islets
    • Green AS, Chen X, Macko AR, Anderson MJ, Kelly AC, Hart NJ, Lynch RM, Limesand SW. Chronic pulsatile hyperglycemia reduces insulin secretion and increases accumulation of reactive oxygen species in fetal sheep islets. J Endocrinol 212: 327-342, 2012.
    • (2012) J Endocrinol , vol.212 , pp. 327-342
    • Green, A.S.1    Chen, X.2    Macko, A.R.3    Anderson, M.J.4    Kelly, A.C.5    Hart, N.J.6    Lynch, R.M.7    Limesand, S.W.8
  • 19
    • 77952575139 scopus 로고    scopus 로고
    • Consequences of a compromised intrauterine environment on islet function
    • Green AS, Rozance PJ, Limesand SW. Consequences of a compromised intrauterine environment on islet function. J Endocrinol 205: 211-224, 2010.
    • (2010) J Endocrinol , vol.205 , pp. 211-224
    • Green, A.S.1    Rozance, P.J.2    Limesand, S.W.3
  • 21
    • 0345863525 scopus 로고    scopus 로고
    • Validation of surrogate estimates of insulin sensitivity and insulin secretion in children and adolescents
    • Gungor N, Saad R, Janosky J, Arslanian S. Validation of surrogate estimates of insulin sensitivity and insulin secretion in children and adolescents. J Pediatr 144: 47-55, 2004.
    • (2004) J Pediatr , vol.144 , pp. 47-55
    • Gungor, N.1    Saad, R.2    Janosky, J.3    Arslanian, S.4
  • 22
    • 0024585553 scopus 로고
    • The effects of streptozotocin on rates of glucose utilization, oxidation, and production in the sheep fetus
    • Hay WW Jr, Meznarich HK, Fowden AL. The effects of streptozotocin on rates of glucose utilization, oxidation, and production in the sheep fetus. Metabolism 38: 30-37, 1989.
    • (1989) Metabolism , vol.38 , pp. 30-37
    • Hay Jr., W.W.1    Meznarich, H.K.2    Fowden, A.L.3
  • 23
    • 0033847126 scopus 로고    scopus 로고
    • Glucagon receptors on human islet cells contribute to glucose competence of insulin release
    • Huypens P, Ling Z, Pipeleers D, Schuit F. Glucagon receptors on human islet cells contribute to glucose competence of insulin release. Diabetologia 43: 1012-1019, 2000.
    • (2000) Diabetologia , vol.43 , pp. 1012-1019
    • Huypens, P.1    Ling, Z.2    Pipeleers, D.3    Schuit, F.4
  • 24
    • 77949843950 scopus 로고    scopus 로고
    • Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction
    • Leos RA, Anderson MJ, Chen X, Pugmire J, Anderson KA, Limesand SW. Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction. Am J Physiol Endocrinol Metab 298: E770-E778, 2010.
    • (2010) Am J Physiol Endocrinol Metab , vol.298
    • Leos, R.A.1    Anderson, M.J.2    Chen, X.3    Pugmire, J.4    Anderson, K.A.5    Limesand, S.W.6
  • 25
    • 0037440658 scopus 로고    scopus 로고
    • Adaptation of ovine fetal pancreatic insulin secretion to chronic hypoglycaemia and euglycaemic correction
    • Limesand SW, Hay WW Jr. Adaptation of ovine fetal pancreatic insulin secretion to chronic hypoglycaemia and euglycaemic correction. J Physiol 547: 95-105, 2003.
    • (2003) J Physiol , vol.547 , pp. 95-105
    • Limesand, S.W.1    Hay Jr., W.W.2
  • 26
    • 17844371675 scopus 로고    scopus 로고
    • Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction
    • Limesand SW, Jensen J, Hutton JC, Hay WW Jr. Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol 288: R1297-R1305, 2005.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Limesand, S.W.1    Jensen, J.2    Hutton, J.C.3    Hay Jr., W.W.4
  • 27
    • 0347765964 scopus 로고    scopus 로고
    • Characterization of glucose transporter 8 (GLUT8) in the ovine placenta of normal and growth restricted fetuses
    • Limesand SW, Regnault TR, Hay WW Jr. Characterization of glucose transporter 8 (GLUT8) in the ovine placenta of normal and growth restricted fetuses. Placenta 25: 70-77, 2004.
    • (2004) Placenta , vol.25 , pp. 70-77
    • Limesand, S.W.1    Regnault, T.R.2    Hay Jr., W.W.3
  • 28
    • 37149015818 scopus 로고    scopus 로고
    • Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction
    • Limesand SW, Rozance PJ, Smith D, Hay Jr WW. Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction Am J Physiol Endocrinol Metab 293: E1716-E1725, 2007.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Limesand, S.W.1    Rozance, P.J.2    Smith, D.3    Hay Jr., W.W.4
  • 29
    • 32644433563 scopus 로고    scopus 로고
    • Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction
    • Limesand SW, Rozance PJ, Zerbe GO, Hutton JC, Hay WW Jr. Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction. Endocrinology 147: 1488-1497, 2006.
    • (2006) Endocrinology , vol.147 , pp. 1488-1497
    • Limesand, S.W.1    Rozance, P.J.2    Zerbe, G.O.3    Hutton, J.C.4    Hay Jr., W.W.5
  • 30
    • 20644439086 scopus 로고    scopus 로고
    • Ovine fetal metabolism during norepinephrine infusion
    • Milley JR. Ovine fetal metabolism during norepinephrine infusion. Am J Physiol Endocrinol Metab 273: E336-E347, 1997.
    • (1997) Am J Physiol Endocrinol Metab , vol.273
    • Milley, J.R.1
  • 32
    • 0025183588 scopus 로고
    • Effects of fetal intravenous glucose challenge in normal and growth retarded fetuses
    • Nicolini U, Hubinont C, Santolaya J, Fisk NM, Rodeck CH. Effects of fetal intravenous glucose challenge in normal and growth retarded fetuses. Horm Metab Res 22: 426-430, 1990.
    • (1990) Horm Metab Res , vol.22 , pp. 426-430
    • Nicolini, U.1    Hubinont, C.2    Santolaya, J.3    Fisk, N.M.4    Rodeck, C.H.5
  • 34
    • 35648937477 scopus 로고    scopus 로고
    • Restriction of placental growth in sheep impairs insulin secretion but not sensitivity before birth
    • Owens JA, Gatford KL, De Blasio MJ, Edwards LJ, McMillen IC, Fowden AL. Restriction of placental growth in sheep impairs insulin secretion but not sensitivity before birth. J Physiol 584: 935-949, 2007.
    • (2007) J Physiol , vol.584 , pp. 935-949
    • Owens, J.A.1    Gatford, K.L.2    de Blasio, M.J.3    Edwards, L.J.4    McMillen, I.C.5    Fowden, A.L.6
  • 38
    • 43049176238 scopus 로고    scopus 로고
    • Diagnosis of IUGR: Traditional biometry
    • Platz E, Newman R. Diagnosis of IUGR: traditional biometry. Semin Perinatol 32: 140-147, 2008.
    • (2008) Semin Perinatol , vol.32 , pp. 140-147
    • Platz, E.1    Newman, R.2
  • 39
    • 0012746562 scopus 로고    scopus 로고
    • Placental development in normal and compromised pregnancies
    • Regnault TR, Galan HL, Parker TA, Anthony RV. Placental development in normal and compromised pregnancies. Placenta 23, Suppl A: S119-S129, 2002.
    • (2002) Placenta , vol.23 , Issue.SUPPL. A
    • Regnault, T.R.1    Galan, H.L.2    Parker, T.A.3    Anthony, R.V.4
  • 40
    • 0036482127 scopus 로고    scopus 로고
    • Placental expression of VEGF, PlGF and their receptors in a model of placental insufficiency-intrauterine growth restriction (PI-IUGR)
    • Regnault TR, Orbus RJ, de Vrijer B, Davidsen ML, Galan HL, Wilkening RB, Anthony RV. Placental expression of VEGF, PlGF and their receptors in a model of placental insufficiency-intrauterine growth restriction (PI-IUGR). Placenta 23: 132-144, 2002.
    • (2002) Placenta , vol.23 , pp. 132-144
    • Regnault, T.R.1    Orbus, R.J.2    de Vrijer, B.3    Davidsen, M.L.4    Galan, H.L.5    Wilkening, R.B.6    Anthony, R.V.7
  • 42
    • 58149391765 scopus 로고    scopus 로고
    • Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction
    • Rozance PJ, Limesand SW, Barry JS, Brown LD, Hay WW Jr. Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction. Pediatr Res 65: 72-78, 2009.
    • (2009) Pediatr Res , vol.65 , pp. 72-78
    • Rozance, P.J.1    Limesand, S.W.2    Barry, J.S.3    Brown, L.D.4    Hay Jr., W.W.5
  • 43
    • 34247629603 scopus 로고    scopus 로고
    • Chronic fetal hypoglycemia inhibits the later steps of stimulus-secretion coupling in pancreatic β-cells
    • Rozance PJ, Limesand SW, Zerbe GO, Hay Jr WW. Chronic fetal hypoglycemia inhibits the later steps of stimulus-secretion coupling in pancreatic β-cells Am J Physiol Endocrinol Metab 292: E1256-E1264, 2007.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Rozance, P.J.1    Limesand, S.W.2    Zerbe, G.O.3    Hay Jr., W.W.4
  • 44
    • 0001293564 scopus 로고
    • Promotion of insulin secretion by glucagon
    • Samol SE, Marr IG, Mark SV. Promotion of insulin secretion by glucagon. Lancet 2: 415-416, 1965.
    • (1965) Lancet , vol.2 , pp. 415-416
    • Samol, S.E.1    Marr, I.G.2    Mark, S.V.3
  • 45
    • 0004282518 scopus 로고    scopus 로고
    • SAS Institute. Cary, NC: SAS Institute
    • SAS Institute. SAS/STAT User's Guide. Cary, NC: SAS Institute, 1999.
    • (1999) SAS/STAT User's Guide
  • 46
    • 33745097378 scopus 로고    scopus 로고
    • Insulin sensitivity and insulin secretion at birth in intrauterine growth retarded infants
    • Setia S, Sridhar MG, Bhat V, Chaturvedula L, Vinayagamoorti R, John M. Insulin sensitivity and insulin secretion at birth in intrauterine growth retarded infants. Pathology 38: 236-238, 2006.
    • (2006) Pathology , vol.38 , pp. 236-238
    • Setia, S.1    Sridhar, M.G.2    Bhat, V.3    Chaturvedula, L.4    Vinayagamoorti, R.5    John, M.6
  • 47
    • 84867739465 scopus 로고    scopus 로고
    • Increased hepatic glucose production in fetal sheep with intrauterine growth restriction is not suppressed by insulin
    • Thorn SR, Brown LD, Rozance PJ, Hay WW Jr, Friedman JE. Increased hepatic glucose production in fetal sheep with intrauterine growth restriction is not suppressed by insulin. Diabetes 62: 65-73, 2013.
    • (2013) Diabetes , vol.62 , pp. 65-73
    • Thorn, S.R.1    Brown, L.D.2    Rozance, P.J.3    Hay Jr., W.W.4    Friedman, J.E.5
  • 48
    • 67649658047 scopus 로고    scopus 로고
    • Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle
    • Thorn SR, Regnault TR, Brown LD, Rozance PJ, Keng J, Roper M, Wilkening RB, Hay WW Jr, Friedman JE. Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle. Endocrinology 150: 3021-3030, 2009.
    • (2009) Endocrinology , vol.150 , pp. 3021-3030
    • Thorn, S.R.1    Regnault, T.R.2    Brown, L.D.3    Rozance, P.J.4    Keng, J.5    Roper, M.6    Wilkening, R.B.7    Hay Jr., W.W.8    Friedman, J.E.9
  • 52
    • 84866181153 scopus 로고    scopus 로고
    • Developmental programming in response to intrauterine growth restriction impairs myoblast function and skeletal muscle metabolism
    • doi: 10.1155/2012/631038
    • Yates DT, Macko AR, Nearing M, Chen X, Rhoads RP, Limesand SW. Developmental programming in response to intrauterine growth restriction impairs myoblast function and skeletal muscle metabolism. J Pregnancy. doi: 10.1155/2012/631038.
    • J Pregnancy
    • Yates, D.T.1    Macko, A.R.2    Nearing, M.3    Chen, X.4    Rhoads, R.P.5    Limesand, S.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.