메뉴 건너뛰기




Volumn 298, Issue 4, 2010, Pages

Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction

Author keywords

Fetal growth restriction; Glucose stimulated insulin secretion; Hypoxia; Islets of langerhans; Pancreas

Indexed keywords

ADRENALIN; ALPHA 1D ADRENERGIC RECEPTOR; ALPHA 2A ADRENERGIC RECEPTOR; ALPHA 2B ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; GLUCOSE; INSULIN; MESSENGER RNA; NORADRENALIN; PHENTOLAMINE; PROPRANOLOL;

EID: 77949843950     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00494.2009     Document Type: Article
Times cited : (82)

References (55)
  • 2
    • 0031775878 scopus 로고    scopus 로고
    • Catecholamines inhibit growth in fetal sheep in the absence of hypoxemia
    • Bassett JM, Hanson C. Catecholamines inhibit growth in fetal sheep in the absence of hypoxemia. Am J Physiol Regul Integr Comp Physiol 274: R1536-R1545, 1998.
    • (1998) Am J Physiol Regul Integr Comp Physiol , vol.274
    • Bassett, J.M.1    Hanson, C.2
  • 3
    • 0034080030 scopus 로고    scopus 로고
    • Prevention of hypoinsulinemia modifies catecholamine effects in fetal sheep
    • Bassett JM, Hanson C. Prevention of hypoinsulinemia modifies catecholamine effects in fetal sheep. Am J Physiol Regul Integr Comp Physiol 278: R1171-R1181, 2000.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.278
    • Bassett, J.M.1    Hanson, C.2
  • 4
    • 0031843552 scopus 로고    scopus 로고
    • Beta2-agonist ritodrine, unlike natural catecholamines, activates thermogenesis prematurely in fetal sheep
    • Bassett JM, Symonds ME. Beta2-agonist ritodrine, unlike natural catecholamines, activates thermogenesis prematurely in fetal sheep. Am J Physiol Regul Integr Comp Physiol 275: R112-R119, 1998.
    • (1998) Am J Physiol Regul Integr Comp Physiol , vol.275
    • Bassett, J.M.1    Symonds, M.E.2
  • 5
    • 0023102686 scopus 로고
    • Some aspects of placental function in chronically heat-stressed ewes
    • Bell AW, Wilkening RB, Meschia G. Some aspects of placental function in chronically heat-stressed ewes. J Dev Physiol 9: 17-29, 1987.
    • (1987) J Dev Physiol , vol.9 , pp. 17-29
    • Bell, A.W.1    Wilkening, R.B.2    Meschia, G.3
  • 8
    • 0025310140 scopus 로고
    • Fetal adrenal medulla catecholamine response to hypoxia-direct and neural components
    • Cheung CY. Fetal adrenal medulla catecholamine response to hypoxia-direct and neural components. Am J Physiol Regul Integr Comp Physiol 258: R1340-R1346, 1990.
    • (1990) Am J Physiol Regul Integr Comp Physiol , vol.258
    • Cheung, C.Y.1
  • 9
    • 70349778139 scopus 로고    scopus 로고
    • One process for pancreatic β-cell coalescence into islets involves an epithelial- mesenchymal transition
    • Cole L, Anderson MJ, Antin PB, Limesand SW. One process for pancreatic β-cell coalescence into islets involves an epithelial- mesenchymal transition. J Endocrinol 203: 19-31, 2009.
    • (2009) J Endocrinol , vol.203 , pp. 19-31
    • Cole, L.1    Anderson, M.J.2    Antin, P.B.3    Limesand, S.W.4
  • 10
    • 0025973966 scopus 로고
    • Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression
    • Collins S, Caron MG, Lefkowitz RJ. Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression. Annu Rev Physiol 53: 497-508: 497-508, 1991.
    • (1991) Annu Rev Physiol , vol.53
    • Collins, S.1    Caron, M.G.2    Lefkowitz, R.J.3
  • 11
    • 0002081804 scopus 로고    scopus 로고
    • Intrauterine Growth Restriction
    • edited by Creasy RK and Resnik R. Philadelphia, PA: Saunders
    • Creasy RK, Resnik R. Intrauterine Growth Restriction. In: Maternal-Fetal Medicine, edited by Creasy RK and Resnik R. Philadelphia, PA: Saunders, 1999, p. 569-584.
    • (1999) Maternal-Fetal Medicine , pp. 569-584
    • Creasy, R.K.1    Resnik, R.2
  • 12
    • 14944351248 scopus 로고    scopus 로고
    • Restriction of placental growth results in greater hypotensive response to alpha-adrenergic blockade in fetal sheep during late gestation
    • Danielson L, McMillen IC, Dyer JL, Morrison JL. Restriction of placental growth results in greater hypotensive response to alpha-adrenergic blockade in fetal sheep during late gestation. J Physiol 563: 611-620, 2005.
    • (2005) J Physiol , vol.563 , pp. 611-620
    • Danielson, L.1    McMillen, I.C.2    Dyer, J.L.3    Morrison, J.L.4
  • 13
    • 33847069270 scopus 로고    scopus 로고
    • Placental restriction of fetal growth increases insulin action, growth, and adiposity in the young lamb
    • De Blasio MJ, Gatford KL, McMillen IC, Robinson JS, Owens JA. Placental restriction of fetal growth increases insulin action, growth, and adiposity in the young lamb. Endocrinology 148: 1350-1358, 2007.
    • (2007) Endocrinology , vol.148 , pp. 1350-1358
    • De Blasio, M.J.1    Gatford, K.L.2    McMillen, I.C.3    Robinson, J.S.4    Owens, J.A.5
  • 15
    • 33745215673 scopus 로고    scopus 로고
    • Mechanisms by which poor early growth programs type-2 diabetes, obesity and the metabolic syndrome
    • Fernandez-Twinn DS, Ozanne SE. Mechanisms by which poor early growth programs type-2 diabetes, obesity and the metabolic syndrome. Physiol Behav 88: 234-243, 2006.
    • (2006) Physiol Behav , vol.88 , pp. 234-243
    • Fernandez-Twinn, D.S.1    Ozanne, S.E.2
  • 16
    • 0018953138 scopus 로고
    • Effects of adrenaline and amino acids on the release of insulin in the sheep fetus
    • Fowden AL. Effects of adrenaline and amino acids on the release of insulin in the sheep fetus. J Endocrinol 87: 113-121, 1980.
    • (1980) J Endocrinol , vol.87 , pp. 113-121
    • Fowden, A.L.1
  • 17
    • 0030798732 scopus 로고    scopus 로고
    • In utero undernutrition impairs rat beta-cell development
    • Garofano A, Czernichow P, Breant B. In utero undernutrition impairs rat beta-cell development. Diabetologia 40: 1231-1234, 1997.
    • (1997) Diabetologia , vol.40 , pp. 1231-1234
    • Garofano, A.1    Czernichow, P.2    Breant, B.3
  • 18
    • 0026772772 scopus 로고
    • Type 2 (non-insulin-dependent) diabetes mellitus: The thrifty phenotype hypothesis
    • Hales CN, Barker DJ. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 35: 595-601, 1992.
    • (1992) Diabetologia , vol.35 , pp. 595-601
    • Hales, C.N.1    Barker, D.J.2
  • 20
    • 0027425033 scopus 로고
    • Hypoxia-induced sympathetic inhibition of the fetal plasma insulin response to hyperglycemia
    • Jackson BT, Cohn HE, Morrison SH, Baker RM, Piasecki GJ. Hypoxia-induced sympathetic inhibition of the fetal plasma insulin response to hyperglycemia. Diabetes 42: 1621-1625, 1993.
    • (1993) Diabetes , vol.42 , pp. 1621-1625
    • Jackson, B.T.1    Cohn, H.E.2    Morrison, S.H.3    Baker, R.M.4    Piasecki, G.J.5
  • 22
    • 0033556082 scopus 로고    scopus 로고
    • Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion
    • Lang J. Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion. Eur J Biochem 259: 3-17, 1999.
    • (1999) Eur J Biochem , vol.259 , pp. 3-17
    • Lang, J.1
  • 23
    • 0037440658 scopus 로고    scopus 로고
    • Adaptation of ovine fetal pancreatic insulin secretion to chronic hypoglycaemia and euglycaemic correction
    • Limesand SW, Hay WW Jr. Adaptation of ovine fetal pancreatic insulin secretion to chronic hypoglycaemia and euglycaemic correction. J Physiol 547: 95-105, 2003.
    • (2003) J Physiol , vol.547 , pp. 95-105
    • Limesand, S.W.1    Hay Jr., W.W.2
  • 24
    • 17844371675 scopus 로고    scopus 로고
    • Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction
    • Limesand SW, Jensen J, Hutton JC, Hay WW Jr. Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol 288: R1297-R1305, 2005.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Limesand, S.W.1    Jensen, J.2    Hutton, J.C.3    Hay Jr., W.W.4
  • 25
    • 0347765964 scopus 로고    scopus 로고
    • Characterization of glucose transporter 8 (GLUT8) in the ovine placenta of normal and growth restricted fetuses
    • Limesand SW, Regnault TR, Hay WW Jr. Characterization of glucose transporter 8 (GLUT8) in the ovine placenta of normal and growth restricted fetuses. Placenta 25: 70-77, 2004.
    • (2004) Placenta , vol.25 , pp. 70-77
    • Limesand, S.W.1    Regnault, T.R.2    Hay Jr., W.W.3
  • 26
    • 37149015818 scopus 로고    scopus 로고
    • Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction
    • Limesand SW, Rozance PJ, Smith D, Hay WW Jr. Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction. Am J Physiol Endocrinol Metab 293: E1716-E1725, 2007.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Limesand, S.W.1    Rozance, P.J.2    Smith, D.3    Hay Jr., W.W.4
  • 27
    • 32644433563 scopus 로고    scopus 로고
    • Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction
    • Limesand SW, Rozance PJ, Zerbe GO, Hutton JC, Hay WW Jr. Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction. Endocrinology 147: 1488-1497, 2006.
    • (2006) Endocrinology , vol.147 , pp. 1488-1497
    • Limesand, S.W.1    Rozance, P.J.2    Zerbe, G.O.3    Hutton, J.C.4    Hay Jr., W.W.5
  • 29
    • 20644439086 scopus 로고    scopus 로고
    • Ovine fetal metabolism during norepinephrine infusion
    • Milley JR. Ovine fetal metabolism during norepinephrine infusion. Am J Physiol Endocrinol Metab 273: E336-E347, 1997.
    • (1997) Am J Physiol Endocrinol Metab , vol.273
    • Milley, J.R.1
  • 30
    • 0021910462 scopus 로고
    • Studies on the mechanism of inhibition of glucose-stimulated insulin secretion by noradrenaline in rat islets of Langerhans
    • Morgan NG, Montague W. Studies on the mechanism of inhibition of glucose-stimulated insulin secretion by noradrenaline in rat islets of Langerhans. Biochem J 226: 571-576, 1985.
    • (1985) Biochem J , vol.226 , pp. 571-576
    • Morgan, N.G.1    Montague, W.2
  • 31
    • 0025183588 scopus 로고
    • Effects of fetal intravenous glucose challenge in normal and growth retarded fetuses
    • Nicolini U, Hubinont C, Santolaya J, Fisk NM, Rodeck CH. Effects of fetal intravenous glucose challenge in normal and growth retarded fetuses. Horm Metab Res 22: 426-430, 1990.
    • (1990) Horm Metab Res , vol.22 , pp. 426-430
    • Nicolini, U.1    Hubinont, C.2    Santolaya, J.3    Fisk, N.M.4    Rodeck, C.H.5
  • 32
    • 0025167006 scopus 로고
    • Pharmacological characterization of alpha-2 adrenergic receptor subtype involved in the release of insulin from isolated rat pancreatic islets
    • Niddam R, Angel I, Bidet S, Langer SZ. Pharmacological characterization of alpha-2 adrenergic receptor subtype involved in the release of insulin from isolated rat pancreatic islets. J Pharmacol Exp Ther 254: 883-887, 1990.
    • (1990) J Pharmacol Exp Ther , vol.254 , pp. 883-887
    • Niddam, R.1    Angel, I.2    Bidet, S.3    Langer, S.Z.4
  • 35
    • 0142247456 scopus 로고    scopus 로고
    • Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice
    • Peterhoff M, Sieg A, Brede M, Chao CM, Hein L, Ullrich S. Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice. Eur J Endocrinol 149: 343-350, 2003.
    • (2003) Eur J Endocrinol , vol.149 , pp. 343-350
    • Peterhoff, M.1    Sieg, A.2    Brede, M.3    Chao, C.M.4    Hein, L.5    Ullrich, S.6
  • 37
    • 0012746562 scopus 로고    scopus 로고
    • Regnault TR, Galan HL, Parker TA, Anthony RV. Placental development in normal and compromised pregnancies. Placenta 23, Suppl A: S119-S129, 2002.
    • Regnault TR, Galan HL, Parker TA, Anthony RV. Placental development in normal and compromised pregnancies. Placenta 23, Suppl A: S119-S129, 2002.
  • 38
    • 34948899336 scopus 로고    scopus 로고
    • Estimation of beta-cell mass by metabolic tests: Necessary, but how sufficient?
    • Robertson RP. Estimation of beta-cell mass by metabolic tests: necessary, but how sufficient? Diabetes 56: 2420-2424, 2007.
    • (2007) Diabetes , vol.56 , pp. 2420-2424
    • Robertson, R.P.1
  • 39
    • 58149391765 scopus 로고    scopus 로고
    • Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction
    • Rozance PJ, Limesand SW, Barry JS, Brown LD, Hay WW Jr. Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction. Pediatr Res 65: 72-78, 2009.
    • (2009) Pediatr Res , vol.65 , pp. 72-78
    • Rozance, P.J.1    Limesand, S.W.2    Barry, J.S.3    Brown, L.D.4    Hay Jr., W.W.5
  • 40
    • 33745814724 scopus 로고    scopus 로고
    • Decreased Nutrient-stimulated insulin secretion in chronically hypoglycemic late-gestation fetal sheep is due to an intrinsic islet defect
    • Rozance PJ, Limesand SW, Hay WW Jr. Decreased Nutrient-stimulated insulin secretion in chronically hypoglycemic late-gestation fetal sheep is due to an intrinsic islet defect. Am J Physiol Endocrinol Metab 291: E404-E411, 2006.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Rozance, P.J.1    Limesand, S.W.2    Hay Jr., W.W.3
  • 41
    • 40049101847 scopus 로고    scopus 로고
    • Effects of twin pregnancy and periconceptional undernutrition on maternal metabolism, fetal growth and glucose-insulin axis function in ovine pregnancy
    • Rumball CW, Harding JE, Oliver MH, Bloomfield FH. Effects of twin pregnancy and periconceptional undernutrition on maternal metabolism, fetal growth and glucose-insulin axis function in ovine pregnancy. J Physiol 586: 1399-1411, 2008.
    • (2008) J Physiol , vol.586 , pp. 1399-1411
    • Rumball, C.W.1    Harding, J.E.2    Oliver, M.H.3    Bloomfield, F.H.4
  • 42
    • 0032526018 scopus 로고    scopus 로고
    • Oxygen-sensing mechanisms are present in the chromaffin cells of the sheep adrenal medulla before birth
    • Rychkov GY, Adams MB, McMillen IC, Roberts ML. Oxygen-sensing mechanisms are present in the chromaffin cells of the sheep adrenal medulla before birth. J Physiol 509: 887-893, 1998.
    • (1998) J Physiol , vol.509 , pp. 887-893
    • Rychkov, G.Y.1    Adams, M.B.2    McMillen, I.C.3    Roberts, M.L.4
  • 43
    • 0004282518 scopus 로고    scopus 로고
    • SAS Institute Inc, Cary, NC: SAS Institute
    • SAS Institute Inc. SAS/STAT User's Guide. Cary, NC: SAS Institute, 1999.
    • (1999) SAS/STAT User's Guide
  • 44
    • 37449004981 scopus 로고    scopus 로고
    • Reduced blood glucose levels, increased insulin levels and improved glucose tolerance in alpha2A-adrenoceptor knockout mice
    • Savontaus E, Fagerholm V, Rahkonen O, Scheinin M. Reduced blood glucose levels, increased insulin levels and improved glucose tolerance in alpha2A-adrenoceptor knockout mice. Eur J Pharmacol 578: 359-364, 2008.
    • (2008) Eur J Pharmacol , vol.578 , pp. 359-364
    • Savontaus, E.1    Fagerholm, V.2    Rahkonen, O.3    Scheinin, M.4
  • 46
    • 0030474003 scopus 로고    scopus 로고
    • Mechanisms of inhibition of insulin release
    • Sharp GW. Mechanisms of inhibition of insulin release. Am J Physiol Cell Physiol 271: C1781-C1799, 1996.
    • (1996) Am J Physiol Cell Physiol , vol.271
    • Sharp, G.W.1
  • 47
    • 0035489035 scopus 로고    scopus 로고
    • Intrauterine growth retardation leads to the development of type 2 diabetes in the rat
    • Simmons RA, Templeton LJ, Gertz SJ. Intrauterine growth retardation leads to the development of type 2 diabetes in the rat. Diabetes 50: 2279-2286, 2001.
    • (2001) Diabetes , vol.50 , pp. 2279-2286
    • Simmons, R.A.1    Templeton, L.J.2    Gertz, S.J.3
  • 48
    • 0025124447 scopus 로고
    • Effect of a low protein diet during pregnancy on the fetal rat endocrine pancreas
    • Snoeck A, Remacle C, Reusens B, Hoet JJ. Effect of a low protein diet during pregnancy on the fetal rat endocrine pancreas. Biol Neonate 57: 107-118, 1990.
    • (1990) Biol Neonate , vol.57 , pp. 107-118
    • Snoeck, A.1    Remacle, C.2    Reusens, B.3    Hoet, J.J.4
  • 49
    • 0018906693 scopus 로고
    • Adrenergic modulation of pancreatic hormone secretion in utero: Studies in fetal sheep
    • Sperling MA, Christensen RA, Ganguli S, Anand R. Adrenergic modulation of pancreatic hormone secretion in utero: studies in fetal sheep. Pediatr Res 14: 203-208, 1980.
    • (1980) Pediatr Res , vol.14 , pp. 203-208
    • Sperling, M.A.1    Christensen, R.A.2    Ganguli, S.3    Anand, R.4
  • 51
    • 67649658047 scopus 로고    scopus 로고
    • Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle
    • Thorn SR, Regnault TR, Brown LD, Rozance PJ, Keng J, Roper M, Wilkening RB, Hay WW Jr, Friedman JE. Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle. Endocrinology 150: 3021-3030, 2009.
    • (2009) Endocrinology , vol.150 , pp. 3021-3030
    • Thorn, S.R.1    Regnault, T.R.2    Brown, L.D.3    Rozance, P.J.4    Keng, J.5    Roper, M.6    Wilkening, R.B.7    Hay Jr, W.W.8    Friedman, J.E.9
  • 53
    • 6944237771 scopus 로고    scopus 로고
    • Desensitization of the inhibitory effect of norepinephrine on insulin secretion from pancreatic islets of exercise-trained rats
    • Urano Y, Sakurai T, Ueda H, Ogasawara J, Sakurai T, Takei M, Izawa T. Desensitization of the inhibitory effect of norepinephrine on insulin secretion from pancreatic islets of exercise-trained rats. Metabolism 53: 1424-1432, 2004.
    • (2004) Metabolism , vol.53 , pp. 1424-1432
    • Urano, Y.1    Sakurai, T.2    Ueda, H.3    Ogasawara, J.4    Sakurai, T.5    Takei, M.6    Izawa, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.