Long-term exposure to concentrated ambient PM2.5 increases mouse blood pressure through abnormal activation of the sympathetic nervous system: A role for hypothalamic inflammation

Environmental Health Perspectives

Volumn 122, Issue 1, 2014, Pages 79-86

  Ying, Zhekang ^a,b   Xu, Xiaohua ^a,c   Bai, Yuntao ^c   Zhong, Jixin ^a   Chen, Minjie ^a,b   Liang, Yijia ^a   Zhao, Jinzhuo ^c   Liu, Dongyao ^c   Morishita, Masako ^d   Sun, Qinghua ^a,c   Spino, Catherine ^d   Brook, Robert D ^d   Harkema, Jack R ^e   Rajagopalan, Sanjay ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^c OHIO STATE UNIVERSITY   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ATROPINE; CATECHOLAMINE; ENDOTHELIN 1; GUANFACINE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE SYNTHASE; NORADRENALIN; PHENYLEPHRINE; PROPRANOLOL; SELENIUM; SULFUR;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FOURIER TRANSFORMATION; HEART RATE; HUMIDITY; HYPERTENSION; HYPOTHALAMIC INFLAMMATION; IMMUNOFLUORESCENCE; INFLAMMATION; LOCOMOTION; MALE; MEAN ARTERIAL PRESSURE; MOUSE; MYOGRAPHY; NONHUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPECTROSCOPY; SYMPATHETIC TONE; TELEMETRY; TEMPERATURE; VASODILATATION;

AIR POLLUTANTS; ANIMALS; BLOOD PRESSURE; HYPOTHALAMUS; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; PARTICULATE MATTER; SYMPATHETIC NERVOUS SYSTEM;

EID: 84891507300     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1307151     Document Type: Article

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