Ambient particulates alter vascular function through induction of reactive oxygen and nitrogen species

Toxicological Sciences

Volumn 111, Issue 1, 2009, Pages 80-88

  Ying, Zhekang ^a   Kampfrath, Thomas ^a   Thurston, George ^b   Farrar, Britten ^a   Lippmann, Mort ^b   Wang, Aixia ^a   Sun, Qinghua ^a   Chen, Lung Chi ^b   Rajagopalan, Sanjay ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Air pollution; ApoE mice; Atherosclerosis; CAPs; PM2.5; Reactive nitrogen species; Reactive oxygen species

Indexed keywords

ACETYLCHOLINE; APOLIPOPROTEIN E; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; INDUCIBLE NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; RAC1 PROTEIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SMOOTH MUSCLE ACTIN; TETRAHYDROBIOPTERIN;

AIR POLLUTION; ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR RESPONSE; CELL SEPARATION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT ASSESSMENT; ENZYME SYNTHESIS; GENE EXPRESSION; HEART CONTRACTION; HEART MUSCLE RELAXATION; IMMUNOHISTOCHEMISTRY; INHALATION; LIPID COMPOSITION; MACROPHAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARTICULATE MATTER;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BLOOD VESSELS; IMMUNOHISTOCHEMISTRY; INHALATION EXPOSURE; LUMINESCENCE; MALE; MICE; MICE, KNOCKOUT; MUSCLE TONUS; MUSCLE, SMOOTH, VASCULAR; NADPH OXIDASE; PARTICULATE MATTER; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; VASODILATOR AGENTS;

MUS;

EID: 69049090923     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp004     Document Type: Article

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