Melanocortin-4 receptor-deficient mice are not hypertensive or salt-sensitive despite obesity, hyperinsulinemia, and hyperleptinemia

Hypertension

Volumn 46, Issue 2, 2005, Pages 326-332

  Tallam, Lakshmi S ^a   Stec, David E ^a   Willis, Mary A ^a   Da Silva, Alexandre A ^a   Hall, John E ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Arterial pressure; Hypertension, sodium dependent; Insulin resistance; Obesity; Renin angiotensin system

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; DIPEPTIDYL CARBOXYPEPTIDASE; INSULIN; LEPTIN; MELANOCORTIN 4 RECEPTOR; RENIN; RNA 18S; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUID INTAKE; FOOD INTAKE; GENOTYPE; HEART RATE; HYPERINSULINEMIA; HYPERLEPTINEMIA; HYPERTENSION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; KIDNEY; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WEIGHT GAIN;

ADIPOSE TISSUE; ANIMALS; BLOOD PRESSURE; BODY SIZE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING; EATING; HEART RATE; HORMONES; HYPERINSULINISM; HYPERTENSION; LEPTIN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY; RECEPTOR, MELANOCORTIN, TYPE 4; SODIUM CHLORIDE; SODIUM CHLORIDE, DIETARY; VISCERA; WEIGHT GAIN;

EID: 23244451186     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000175474.99326.bf     Document Type: Article

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