Molecular insights on TNKS1/TNKS2 and inhibitor-IWR1 interactions

Molecular BioSystems

Volumn 10, Issue 2, 2014, Pages 281-293

  Kirubakaran, Palani ^a   Kothandan, Gugan ^b   Cho, Seung J ^b   Muthusamy, Karthikeyan ^a  

^a ALAGAPPA UNIVERSITY   (India)

^b Chosun University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; ENZYME INHIBITOR; IMIDE; IWR 1 COMPOUND; IWR-1 COMPOUND; QUINOLINE DERIVATIVE; TANKYRASE; TNKS PROTEIN, HUMAN; TNKS2 PROTEIN, HUMAN; TYROSINE; ZINC;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DATABASE; ENZYME ACTIVE SITE; HUMAN; METABOLISM; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ASPARAGINE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DATABASES, PHARMACEUTICAL; ENZYME INHIBITORS; HUMANS; IMIDES; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; QUINOLINES; TANKYRASES; THERMODYNAMICS; TYROSINE; ZINC;

EID: 84891479452     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/c3mb70305c     Document Type: Article

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