In silico structural and functional analysis of the human TOPK protein by structure modeling and molecular dynamics studies

Journal of Molecular Modeling

Volumn 19, Issue 1, 2013, Pages 407-419

  Kirubakaran, Palani ^a   Karthikeyan, Muthusamy ^a   Singh, Kh Dhanachandra ^a   Nagamani, Selvaraman ^a   Premkumar, Kumpati ^b  

^a ALAGAPPA UNIVERSITY   (India)

^b BHARATHIDASAN UNIVERSITY   (India)

Author keywords

Cancer; Drug design; Electrostatic potential surface; Homology modeling; Molecular dynamics; Protein protein interaction; TOPK

Indexed keywords

CYCLIN DEPENDENT KINASE 1; PROTEIN KINASE; T LYMPHOKINE ACTIVATED KILLER CELL ORIGINATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER MODEL; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STATIC ELECTRICITY;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; COMPUTER SIMULATION; HUMANS; LIGANDS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PROTEIN STRUCTURE, SECONDARY; REPRODUCIBILITY OF RESULTS; SEQUENCE ALIGNMENT; STATIC ELECTRICITY; STRUCTURAL HOMOLOGY, PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS; TIME FACTORS;

EID: 84872357048     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-012-1566-1     Document Type: Article

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