Identifying, by first-principles simulations, Cu[Amyloid-β] species making Fenton-type reactions in Alzheimer's disease

Journal of Physical Chemistry B

Volumn 117, Issue 51, 2013, Pages 16455-16467

  La Penna, Giovanni ^a   Hureau, Christelle ^b   Andreussi, Oliviero ^c   Faller, Peter ^b  

^a ICCOM CNR   (Italy)

^b LCC LABORATOIRE DE CHIMIE DE COORDINATION   (France)

^c UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; COMPUTATIONAL MODEL; FIRST-PRINCIPLES SIMULATIONS; HIGH REACTIVITY; HYDROXYL RADICALS; PRODUCTION OF HYDROGEN; REACTIVE OXYGEN SPECIES; STRUCTURE-FUNCTION RELATIONSHIP;

GLYCOPROTEINS; LAKES; METAL IONS; NEURODEGENERATIVE DISEASES; OLIGOMERS; PEPTIDES; PEROXIDES;

COPPER COMPOUNDS;

AMYLOID BETA PROTEIN; COPPER; FENTON'S REAGENT; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IRON; LIGAND;

ALZHEIMER DISEASE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; OXIDATION REDUCTION REACTION; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; COPPER; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IRON; LIGANDS; MODELS, MOLECULAR; OXIDATION-REDUCTION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY;

EID: 84891399056     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp410046w     Document Type: Article

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