-
1
-
-
0037386086
-
The metallobiology of Alzheimer's disease
-
DOI 10.1016/S0166-2236(03)00067-5
-
Bush, A. I. The metallobiology of Alzheimer's disease Trends Neurosci. 2003, 26, 207-214 (Pubitemid 36412003)
-
(2003)
Trends in Neurosciences
, vol.26
, Issue.4
, pp. 207-214
-
-
Bush, A.I.1
-
2
-
-
77956647381
-
Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease
-
Duce, J. A.; Tsatsanis, A.; Cater, M. A.; James, S. A.; Robb, E.; Wikhe, K.; Leong, S. L.; Perez, K.; Johanssen, T.; Greenough, M. A.; Cho, H.-H.; Galatis, D.; Moir, R. D.; Masters, C. L.; McLean, C.; Tanzi, R. E.; Cappai, R.; Barnham, K. J.; Ciccotosto, G. D.; Rogers, J. T.; Bush, A. I. Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease Cell 2010, 142, 857-867
-
(2010)
Cell
, vol.142
, pp. 857-867
-
-
Duce, J.A.1
Tsatsanis, A.2
Cater, M.A.3
James, S.A.4
Robb, E.5
Wikhe, K.6
Leong, S.L.7
Perez, K.8
Johanssen, T.9
Greenough, M.A.10
Cho, H.-H.11
Galatis, D.12
Moir, R.D.13
Masters, C.L.14
McLean, C.15
Tanzi, R.E.16
Cappai, R.17
Barnham, K.J.18
Ciccotosto, G.D.19
Rogers, J.T.20
Bush, A.I.21
more..
-
3
-
-
44549087765
-
Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
-
Selkoe, D. J. Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior Behav. Brain Res. 2008, 192, 106-113
-
(2008)
Behav. Brain Res.
, vol.192
, pp. 106-113
-
-
Selkoe, D.J.1
-
4
-
-
34547147090
-
The redox chemistry of the Alzheimer's disease amyloid β peptide
-
DOI 10.1016/j.bbamem.2007.02.002, PII S0005273607000387
-
Smith, D. G.; Cappai, R.; Barnham, K. J. The redox chemistry of the Alzheimer's disease amyloid beta peptide Biochim. Biophys. Acta 2007, 1768, 1976-1990 (Pubitemid 47125850)
-
(2007)
Biochimica et Biophysica Acta - Biomembranes
, vol.1768
, Issue.8
, pp. 1976-1990
-
-
Smith, D.G.1
Cappai, R.2
Barnham, K.J.3
-
5
-
-
43049150678
-
Metals in Alzheimer's and Parkinson's Diseases
-
Barnham, K. J.; Bush, A. I. Metals in Alzheimer's and Parkinson's Diseases Curr. Opin. Chem. Biol. 2008, 12, 222-228
-
(2008)
Curr. Opin. Chem. Biol.
, vol.12
, pp. 222-228
-
-
Barnham, K.J.1
Bush, A.I.2
-
6
-
-
72949094439
-
Copper and zinc binding to amyloid-β: Coordination, dynamics, aggregation, reactivity and metal-ion transfer
-
Faller, P. Copper and zinc binding to amyloid-β: coordination, dynamics, aggregation, reactivity and metal-ion transfer ChemBioChem 2009, 10, 2691-2703
-
(2009)
ChemBioChem
, vol.10
, pp. 2691-2703
-
-
Faller, P.1
-
7
-
-
0033601338
-
Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction
-
Huang, X.; Cuajungco, M. P.; Atwood, C. S.; Hartshorn, M. A.; Tyndall, J. D.; Hanson, G. R.; Stokes, K. C.; Leopold, M.; Multhaup, G.; Goldstein, L. E.; Scarpa, R. C.; Saunders, A. J.; Lim, J.; Moir, R. D.; Glabe, C.; Bowden, E. F.; Masters, C. L.; Fairlie, D. P.; Tanzi, R. E.; Bush, A. I. Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction J. Biol. Chem. 1999, 274, 37111-37116
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37111-37116
-
-
Huang, X.1
Cuajungco, M.P.2
Atwood, C.S.3
Hartshorn, M.A.4
Tyndall, J.D.5
Hanson, G.R.6
Stokes, K.C.7
Leopold, M.8
Multhaup, G.9
Goldstein, L.E.10
Scarpa, R.C.11
Saunders, A.J.12
Lim, J.13
Moir, R.D.14
Glabe, C.15
Bowden, E.F.16
Masters, C.L.17
Fairlie, D.P.18
Tanzi, R.E.19
Bush, A.I.20
more..
-
8
-
-
46749100924
-
Therapeutics for Alzheimer's Disease Based on the Metal Hypothesis
-
DOI 10.1016/j.nurt.2008.05.001, PII S1933721308000901
-
Bush, A. I.; Tanzi, R. E. Therapeutics for Alzheimer's disease based on the metal hypothesis Neurotherapeutics 2008, 5, 421-432 (Pubitemid 351952485)
-
(2008)
Neurotherapeutics
, vol.5
, Issue.3
, pp. 421-432
-
-
Bush, A.I.1
Tanzi, R.E.2
-
9
-
-
0035827681
-
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits
-
Curtain, C. C.; Ali, F.; Volitakis, I.; Cherny, R. A.; Norton, R. S.; Beyreuther, K.; Barrow, C. J.; Masters, C. L.; Bush, A. I.; Barnham, K. J. Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits J. Biol. Chem. 2001, 276, 20466-20473
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20466-20473
-
-
Curtain, C.C.1
Ali, F.2
Volitakis, I.3
Cherny, R.A.4
Norton, R.S.5
Beyreuther, K.6
Barrow, C.J.7
Masters, C.L.8
Bush, A.I.9
Barnham, K.J.10
-
10
-
-
0038802776
-
Coordination abilities of the 1-16 and 1-28 fragments of β-amyloid peptide towards copper(II) ions: A combined potentiometric and spectroscopic study
-
DOI 10.1016/S0162-0134(03)00128-4
-
Kowalik-Jankowska, T.; Ruta, M.; Wiśniewska, K.; Łankiewicz, L. Coordination abilities of the 1-16 and 1-28 fragments of β-amyloid peptide towards copper(II) ions: a combined potentiometric and spectroscopic study J. Inorg. Biochem. 2003, 95, 270-282 (Pubitemid 36775348)
-
(2003)
Journal of Inorganic Biochemistry
, vol.95
, Issue.4
, pp. 270-282
-
-
Kowalik-Jankowska, T.1
Ruta, M.2
Wisniewska, K.3
Lankiewicz, L.4
-
12
-
-
2442461177
-
Copper binding to the amyloid-β peptide associated with Alzheimer's disease
-
Syme, C. D.; Nadal, R. C.; Rigby, S. E.; Viles, J. H. Copper binding to the amyloid-β peptide associated with Alzheimer's disease J. Biol. Chem. 2004, 279, 18169-18177
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18169-18177
-
-
Syme, C.D.1
Nadal, R.C.2
Rigby, S.E.3
Viles, J.H.4
-
14
-
-
33751245122
-
II amyloid-β16/28 complexes associated with Alzheimer's disease
-
DOI 10.1007/s00775-006-0154-1
-
II amyloid- β 16/28 complexes associated with Alzheimer's disease J. Biol. Inorg. Chem. 2006, 11, 1024-1038 (Pubitemid 44786391)
-
(2006)
Journal of Biological Inorganic Chemistry
, vol.11
, Issue.8
, pp. 1024-1038
-
-
Guilloreau, L.1
Damian, L.2
Coppel, Y.3
Mazarguil, H.4
Winterhalter, M.5
Faller, P.6
-
15
-
-
34247177552
-
Role of aspartate-1 in Cu(II) binding to the amyloid-β peptide of Alzheimer's disease
-
DOI 10.1021/ja068952d
-
Karr, J. W.; Szalai, V. A. Role of aspartate-1 in Cu(II) binding to the amyloid-β peptide of Alzheimer's disease J. Am. Chem. Soc. 2007, 129, 3796-3797 (Pubitemid 46595480)
-
(2007)
Journal of the American Chemical Society
, vol.129
, Issue.13
, pp. 3796-3797
-
-
Karr, J.W.1
Szalai, V.A.2
-
16
-
-
33746335362
-
NMR reveals anomalous copper(II) binding to the amyloid Aβ peptide of Alzheimer's disease
-
Hou, L.; Zagorski, M. G. NMR reveals anomalous copper(II) binding to the amyloid Aβ peptide of Alzheimer's disease J. Am. Chem. Soc. 2006, 128, 9260-92615
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 9260-92615
-
-
Hou, L.1
Zagorski, M.G.2
-
17
-
-
55249123932
-
The structure of the amyloid β-peptide high affinity Copper II binding site in Alzheimer's disease
-
Streltsov, V. A.; Titmuss, S. J.; Epa, V. C.; Barnham, K. J.; Masters, C. L.; Varghese, J. N. The structure of the amyloid β-peptide high affinity Copper II binding site in Alzheimer's disease Biophys. J. 2008, 95, 3447-3456
-
(2008)
Biophys. J.
, vol.95
, pp. 3447-3456
-
-
Streltsov, V.A.1
Titmuss, S.J.2
Epa, V.C.3
Barnham, K.J.4
Masters, C.L.5
Varghese, J.N.6
-
18
-
-
0034643831
-
Metal binding modes of Alzheimer's amyloid β-peptide in insoluble aggregates and soluble complexes
-
DOI 10.1021/bi0002479
-
Miura, T.; Suzuki, K.; Kohata, N.; Takeuchi, H. Metal binding modes of Alzheimer's amyloid β -peptide in insoluble aggregates and soluble complexes Biochemistry 2000, 39, 7024-7031 (Pubitemid 30390396)
-
(2000)
Biochemistry
, vol.39
, Issue.23
, pp. 7024-7031
-
-
Miura, T.1
Suzuki, K.2
Kohata, N.3
Takeuchi, H.4
-
19
-
-
50849126063
-
Direct evidence that all three histidine residues coordinate to Cu(II) in amyloid-beta1-16
-
Shin, B.; Saxena, S. Direct evidence that all three histidine residues coordinate to Cu(II) in amyloid-beta1-16 Biochemistry 2008, 47, 9117-9123
-
(2008)
Biochemistry
, vol.47
, pp. 9117-9123
-
-
Shin, B.1
Saxena, S.2
-
20
-
-
0016369980
-
Structural implications derived from the analysis of EPR spectra of natural and artificial copper proteins
-
Peisach, J.; Blumberg, W. E. Structural implications derived from the analysis of EPR spectra of natural and artificial copper proteins Arch. Biochem. Biophys. 1974, 165, 691-698
-
(1974)
Arch. Biochem. Biophys.
, vol.165
, pp. 691-698
-
-
Peisach, J.1
Blumberg, W.E.2
-
22
-
-
66149161888
-
Copper(II) binding to amyloid-beta fibrils of Alzheimers disease reveals a pico-molar affinity: Stoichiometry and coordination geometry is independent of Aβ Oligomeric Form
-
Sarell, C.; Syme, C.; Rigby, S.; Viles, J. Copper(II) binding to amyloid-beta fibrils of Alzheimers disease reveals a pico-molar affinity: stoichiometry and coordination geometry is independent of Aβ Oligomeric Form Biochemistry 2009, 48, 4388-4402
-
(2009)
Biochemistry
, vol.48
, pp. 4388-4402
-
-
Sarell, C.1
Syme, C.2
Rigby, S.3
Viles, J.4
-
24
-
-
84908778295
-
-
In; Berliner, L. J. Reuben, J. Biological Magnetic Resonance 1; Plenum Press: New York
-
Boas, J. F.; Pilbrow, J. R.; Smith, T. D. In ESR of copper in biological systems; Berliner, L. J.; Reuben, J., Eds.; Biological Magnetic Resonance 1; Plenum Press: New York, 1978; pp 277-342.
-
(1978)
ESR of Copper in Biological Systems
, pp. 277-342
-
-
Boas, J.F.1
Pilbrow, J.R.2
Smith, T.D.3
-
25
-
-
0034350315
-
Electron spin echo envelope modulation (ESEEM) spectroscopy as a tool to investigate the coordination environment of metal centers
-
Deligiannakis, Y.; Louloudi, M.; Hadjiliadis, N. Electron spin echo envelope modulation (ESEEM) spectroscopy as a tool to investigate the coordination environment of metal centers Coord. Chem. Rev. 2000, 204, 1-112
-
(2000)
Coord. Chem. Rev.
, vol.204
, pp. 1-112
-
-
Deligiannakis, Y.1
Louloudi, M.2
Hadjiliadis, N.3
-
26
-
-
34249941302
-
Copper and the prion protein: Methods, structures, function, and disease
-
DOI 10.1146/annurev.physchem.58.032806.104657
-
Millhauser, G. L. Copper and the Prion Protein: Methods, Structures, Function, and Disease Annu. Rev. Phys. Chem. 2007, 58, 299-320 (Pubitemid 46877592)
-
(2007)
Annual Review of Physical Chemistry
, vol.58
, pp. 299-320
-
-
Millhauser, G.L.1
-
27
-
-
0003988115
-
Physical methods in bioinorganic chemistry: Spectroscopy and magnetism
-
In; Que, L. University Science Books: Sausalito CA
-
Chasteen, N. D.; Snetsinger, P. A. Physical methods in bioinorganic chemistry: spectroscopy and magnetism. In Electron paramagnetic resonance of metalloproteins; Que, L., Ed.; University Science Books: Sausalito CA, 2000; p 213.
-
(2000)
Electron Paramagnetic Resonance of Metalloproteins
, pp. 213
-
-
Chasteen, N.D.1
Snetsinger, P.A.2
-
28
-
-
61749097242
-
Pleomorphic Copper Coordination by Alzheimer's Disease Amyloid-β Peptide
-
Drew, S. C.; Noble, C. J.; Masters, C. L.; Hanson, G. R.; Barnham, K. J. Pleomorphic Copper Coordination by Alzheimer's Disease Amyloid-β Peptide J. Am. Chem. Soc. 2009, 131, 1195-1207
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 1195-1207
-
-
Drew, S.C.1
Noble, C.J.2
Masters, C.L.3
Hanson, G.R.4
Barnham, K.J.5
-
29
-
-
25144485008
-
Peak suppression in ESEEM spectra of multinuclear spin systems
-
DOI 10.1016/j.jmr.2005.07.012, PII S1090780705002260
-
Stoll, S.; Calle, C.; Mitrikas, G.; Schweiger, A. Peak suppression in ESEEM spectra of multinuclear spin systems J. Magn. Reson. 2005, 177, 93-101 (Pubitemid 41336668)
-
(2005)
Journal of Magnetic Resonance
, vol.177
, Issue.1
, pp. 93-101
-
-
Stoll, S.1
Calle, C.2
Mitrikas, G.3
Schweiger, A.4
-
30
-
-
59449097016
-
Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide
-
Faller, P.; Hureau, C. Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide Dalton Trans. 2009, 1080-1094
-
(2009)
Dalton Trans.
, pp. 1080-1094
-
-
Faller, P.1
Hureau, C.2
-
31
-
-
67649600828
-
2+ coordination of Alzheimer's disease amyloid-β peptide - Relevance to N-terminally truncated forms
-
2+ coordination of Alzheimer's disease amyloid-β peptide - relevance to N-terminally truncated forms J. Am. Chem. Soc. 2009, 131, 8760-8761
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 8760-8761
-
-
Drew, S.C.1
Masters, C.L.2
Barnham, K.J.3
-
33
-
-
0029849644
-
Full-length amyloid-β(1-42(43)) and amino-terminally modified and truncated amyloid-β42(43) deposit in diffuse plaques
-
Iwatsubo, T; Saido, T. C.; Mann, D. M.; Lee, V. M.; Trojanowski, J. Q. Full-length amyloid-β(1-42(43)) and amino-terminally modified and truncated amyloid-β42(43) deposit in diffuse plaques Am. J. Pathol. 1996, 149, 1823-1830 (Pubitemid 26415203)
-
(1996)
American Journal of Pathology
, vol.149
, Issue.6
, pp. 1823-1830
-
-
Iwatsubo, T.1
Saido, T.C.2
Mann, D.M.A.3
Lee, V.M.-Y.4
Trojanowski, J.Q.5
-
34
-
-
73249137909
-
Deprotonation of the Asp1-Ala2 peptide bond induces modification of the dynamic copper(II) environment in the amyloid-β peptide near physiological pH
-
Hureau, C.; Coppel, Y.; Dorlet, P.; Solari, P. L.; Sayen, S.; Guillon, E.; Sabater, L.; Faller, P. Deprotonation of the Asp1-Ala2 peptide bond induces modification of the dynamic copper(II) environment in the amyloid-β peptide near physiological pH Angew. Chem., Int. Ed. 2009, 48, 9522-9525
-
(2009)
Angew. Chem., Int. Ed.
, vol.48
, pp. 9522-9525
-
-
Hureau, C.1
Coppel, Y.2
Dorlet, P.3
Solari, P.L.4
Sayen, S.5
Guillon, E.6
Sabater, L.7
Faller, P.8
-
36
-
-
72949092936
-
Pulse EPR spectroscopy reveals the coordination sphere of copper(II) ions in the 1-16 amyloid-β peptide: A key role of the first two N-terminus residues
-
Dorlet, P.; Gambarelli, S.; Faller, P.; Hureau, C. Pulse EPR spectroscopy reveals the coordination sphere of copper(II) ions in the 1-16 amyloid-β peptide: A key role of the first two N-terminus residues Angew. Chem., Int. Ed. 2009, 48, 9273-9276
-
(2009)
Angew. Chem., Int. Ed.
, vol.48
, pp. 9273-9276
-
-
Dorlet, P.1
Gambarelli, S.2
Faller, P.3
Hureau, C.4
-
37
-
-
47249113393
-
N-truncated amyloid-β oligomers induce learning impairment and neuronal apoptosis
-
DOI 10.1016/j.neurobiolaging.2007.03.005, PII S0197458007001157
-
Youssef, I.; Florent-Béchard, S.; Malaplate-Armand, C.; Koziel, V.; Bihain, B.; Olivier, J.-L.; Leininger-Muller, B.; Kriem, B.; Oster, T.; Pillot, T. N-truncated amyloid-β oligomers induce learning impairment and neuronal apoptosis Neurobiol. Aging 2008, 29, 1319-1333 (Pubitemid 351981997)
-
(2008)
Neurobiology of Aging
, vol.29
, Issue.9
, pp. 1319-1333
-
-
Youssef, I.1
Florent-Bechard, S.2
Malaplate-Armand, C.3
Koziel, V.4
Bihain, B.5
Olivier, J.-L.6
Leininger-Muller, B.7
Kriem, B.8
Oster, T.9
Pillot, T.10
-
38
-
-
80052210889
-
Substantial contribution of the two imidazole rings of the His13-His14 dyad to Cu(II) binding in amyloid-β(1-16) at physiological pH and its significance
-
H14} mode contributes to component I at physiological pH (; doi: 10.1021/jp200379m).
-
H14} mode contributes to component I at physiological pH (Shin, B.; Saxena, S. Substantial contribution of the two imidazole rings of the His13-His14 dyad to Cu(II) binding in amyloid-β(1-16) at physiological pH and its significance. J. Phys. Chem. A 2011, doi: 10.1021/jp200379m).
-
(2011)
J. Phys. Chem. A
-
-
Shin, B.1
Saxena, S.2
-
39
-
-
70349897996
-
Solid-phase synthesis of homodimeric peptides: Preparation of covalently-linked dimers of amyloid beta peptide
-
Kok, W. M.; Scanlon, D. B.; Karas, J. A.; Miles, L. A.; Tew, D. J.; Parker, M. W.; Barnham, K. J.; Hutton, C. A. Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid beta peptide Chem. Commun. 2009, 6228-6230
-
(2009)
Chem. Commun.
, pp. 6228-6230
-
-
Kok, W.M.1
Scanlon, D.B.2
Karas, J.A.3
Miles, L.A.4
Tew, D.J.5
Parker, M.W.6
Barnham, K.J.7
Hutton, C.A.8
|