Vitamin e D-α-tocopheryl polyethylene glycol 1000 succinate-based nanomedicine

Nanomedicine

Volumn 7, Issue 11, 2012, Pages 1645-1647

  Zhang, Zhiping ^a   Mei, Lin ^b   Feng, Si Shen ^c  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b TSINGHUA UNIVERSITY   (China)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

biodegradable polymers; cancer nanotechnology; drug delivery; drug formulation; molecular biomaterial; oral chemotherapy

Indexed keywords

ALPHA TOCOPHEROL; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; CYCLOSPORIN; DENDRIMER; DIAGNOSTIC AGENT; DOCETAXEL; DOXORUBICIN; FERUCARBOTRAN; IRON OXIDE; LIPOSOME; MACROGOL; NANOCARRIER; NANOPARTICLE; PACLITAXEL; PHOSPHATIDYLETHANOLAMINE; POLYCAPROLACTONE; POLYGLACTIN; POLYGLYCOLIC ACID; POLYLACTIC ACID; PRODRUG; QUANTUM DOT; STEROID; TAXANE DERIVATIVE; TOCOFERSOLAN; TRASTUZUMAB;

BIODEGRADABILITY; CARDIOTOXICITY; CONTROLLED RELEASE FORMULATION; DRUG BIOAVAILABILITY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG FORMULATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG SOLUBILITY; DRUG TARGETING; EMULSION; GASTROINTESTINAL TOXICITY; HUMAN; HYDROGEL; IC 50; MICELLE; NANOMEDICINE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SUSTAINED DRUG RELEASE;

ANIMALS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; NANOMEDICINE; NANOPARTICLES; POLYETHYLENE GLYCOLS; PRODRUGS; VITAMIN E;

EID: 84870582942     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.12.117     Document Type: Review

References (20)

1. Wu SH, Hopkins WK. Characteristics of D a tocopheryl PEG1000 succinate for applications as an absorption enhancer in drug delivery systems. Pharm. Tech. 23, 52-60 (1999).
2. Varma M V, Panchagnula R. Enhanced oral paclitaxel absorption with vitamin E-TPGS: effect on solubility and permeability in vitro, in situ and in vivo. Eur. J. Pharm. Sci. 25, 445-453 (2005).
3. Collnot EM, Baldes C, Wempe MF et al. Infuence of vitamin E TPGS poly(ethylene glycol) chain length on apical effux transporters in Caco-2 cell monolayers. J. Control. Release 111, 35-40 (2006).
4. Collnot EM, Baldes C, Wempe MF et al. Mechanism of inhibition of P-glycoprotein mediated effux by vitamin E TPGS: infuence on ATPase activity and membrane fuidity. Mol. Pharm. 4, 465-474 (2007).
5. Greenwald RB, Choe YH, McGuire J et al. Effective drug delivery by PEGylated drug conjugates. Adv. Drug Deliv. Rev. 55, 217-250 (2003).
6. Cao N, Feng SS. Doxorubicin conjugated to D a tocopheryl polyethylene glycol 1000 succinate (TPGS): conjugation chemistry, characterization, in vitro and in vivo evaluation. Biomaterials 29, 3856-3865 (2008).
7. Anbharasi V, Cao N, Feng SS. Doxorubicin conjugated to D a tocopheryl polyethylene glycol succinate and folic acid as a prodrug for targeted chemotherapy. J. Biomed. Mater. Res. 94(3), 730-743 (2010).
8. Mi Y, Liu YT, Feng SS. Formulation of docetaxel by folic acid-conjugated D a tocopheryl polyethylene glycol succinate 2000 (vitamin E TPGS(2k)) micelles for targeted and synergistic chemotherapy. Biomaterials 32, 4058-4066 (2011).
9. Chandrasekharan P, Maity D, Yong CX et al. Vitamin E (D a tocopheryl-co-poly(ethylene glycol) 1000 succinate) micelles-superparamagnetic iron oxide nanoparticles for enhanced thermotherapy and MRI. Biomaterials 32, 5663-5672 (2011).
10. Muthu MS, Kulkarni SA, Xiong J et al. Vitamin E TPGS coated liposomes enhanced cellular uptake and cytotoxicity of docetaxel in brain cancer cells. Int. J. Pharm. 421, 332-340 (2011).
11. Cheow WS, Hadinoto K. Factors affecting drug encapsulation and stability of lipid-polymer hybrid nanoparticles. Colloid Surf. B 85, 214-220 (2011).
12. Feng SS. New-concept chemotherapy by nanoparticles of biodegradable polymers: where are we now? Nanomedicine (Lond.) 1, 297-309 (2006).
13. Feng SS, Zhao LY, Zhang ZP et al. Chemotherapeutic engineering: vitamin E TPGS-emulsifed nanoparticles of biodegradable polymers realized sustainable paclitaxel chemotherapy for 168 h in vivo. Chem. Eng. Sci. 62, 6641-6648 (2007).
14. Zhao LY, Feng SS. Enhanced oral bioavailability of paclitaxel formulated in vitamin E TPGS emulsifed nanoparticles of biodegradable polymers: in vitro and in vivo studies. J. Pharm. Sci. 99, 3552-3560 (2010).
15. Zhang Z P, Feng SS. Nanoparticles of poly(lactide)/vitamin E TPGS copolymer for cancer chemotherapy: synthesis, formulation, characterization and in vitro drug release. Biomaterials 27, 262-270 (2006).
16. Zhang ZP, Lee SH, Gan CW et al. In vitro and in vivo investigation on PLA-TPGS nanoparticles for controlled and sustained small molecule chemotherapy. Pharm. Res. 25, 1925-1935 (2008).
17. Gan CW, Chien S, Feng SS. Enhancement of chemotherapeutical effcacy of docetaxel by using a biodegradable nanoparticle formulation. Curr. Pharm. Des. 16, 2308-2320 (2010).
18. Feng SS, Mei L, Anitha P et al. Poly(lactide)-vitamin E derivative/montmorillonite nanoparticle formulations for the oral delivery of docetaxel. Biomaterials 30, 3297-3306 (2009).
19. Tan YF, Chandrasekharan P, Maity D et al. Multimodal tumor imaging by iron oxides and quantum dots formulated in poly (lactic acid)-D a tocopheryl polyethylene glycol 1000 succinate nanoparticles. Biomaterials 32, 2969-2978 (2011).
20. Zhang ZP, Yang XL, Feng SS. Copolymer technology for advanced nanomedicine. Nanomedicine (Lond.) 6, 583-587 (2011).