Fabrication of covered porous PLGA microspheres using hydrogen peroxide for controlled drug delivery and regenerative medicine

Journal of Controlled Release

Volumn 133, Issue 1, 2009, Pages 37-43

  Bae, Soon Eon ^a,b   Son, Jun Sik ^a,c   Park, Kwideok ^a   Han, Dong Keun ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Hanyang University   (South Korea)

^c The University of Texas at San Antonio   (United States)

Author keywords

Covered skin layer; Dexamethasone; Drug delivery; Hydrogen peroxide; Porous PLGA microsphere

Indexed keywords

CONTROLLED DRUG DELIVERY; DRUG DELIVERY; EMULSIFICATION; EVAPORATION; HYDROGEN; HYDROGEN PEROXIDE; MOISTURE; NONMETALS; OXIDATION; OXYGEN; POLYMER BLENDS; SKIN; VAPORS;

BIOLOGICALLY ACTIVE PROTEINS; COVERED SKIN LAYER; DEXAMETHASONE; DOUBLE EMULSIONS; ENZYMATIC REACTIONS; GLYCOLIC ACIDS; GLYCOLIDE; IN VITRO; INTERNAL PORES; LACTIDE; MOLAR RATIOS; OXYGEN BUBBLES; PLGA MICROSPHERES; POROGEN; POROUS MICROSTRUCTURES; POROUS NETWORKS; POROUS PLGA MICROSPHERE; POROUS STRUCTURES; REGENERATIVE MEDICINES; RELEASE PROFILES; SKIN LAYERS;

MICROSPHERES;

CATALASE; DEXAMETHASONE; HYDROGEN PEROXIDE; MICROSPHERE; POLYGLACTIN; POLYVINYL ALCOHOL;

ARTICLE; CONTROLLED DRUG RELEASE; DRUG DELIVERY SYSTEM; ENZYME MECHANISM; EVAPORATION; INFRARED SPECTROSCOPY; MOLECULAR WEIGHT; POROSITY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REGENERATIVE MEDICINE;

ANTI-INFLAMMATORY AGENTS; BIOCOMPATIBLE MATERIALS; CALORIMETRY, DIFFERENTIAL SCANNING; CATALASE; CHROMATOGRAPHY, GEL; DELAYED-ACTION PREPARATIONS; DEXAMETHASONE; HYDROGEN PEROXIDE; LACTIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MOLECULAR WEIGHT; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYVINYL ALCOHOL; POROSITY; REGENERATIVE MEDICINE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES;

EID: 57049124830     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.09.006     Document Type: Article

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