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Volumn 10, Issue 8, 2009, Pages 836-841

Therapeutic nanoparticles to combat cancer drug resistance

Author keywords

Cancer chemoresistance; Combination therapy; Endocytic uptake; Long circulation; Nanoparticle drug delivery; Stimuli responsive drug release; Targeted delivery

Indexed keywords

ANTINEOPLASTIC AGENT; ARGINYLGLYCYLASPARTIC ACID; CURCUMIN; CYCLOSPORIN A; DOXORUBICIN; MACROGOL; NANOPARTICLE; PACLITAXEL; POLYCAPROLACTONE; POLYLACTIC ACID;

EID: 74249101977     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920009790274540     Document Type: Review
Times cited : (201)

References (58)
  • 1
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance
    • Gottesman, M. M. Mechanisms of cancer drug resistance. Annu. Rev. Med., 2002, 53, 615-627.
    • (2002) Annu. Rev. Med , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 2
    • 0028470454 scopus 로고
    • Barriers to drug delivery in solid tumors
    • Jain, R. K. Barriers to drug delivery in solid tumors. Sci. Am., 1994, 271(1), 58-65.
    • (1994) Sci. Am , vol.271 , Issue.1 , pp. 58-65
    • Jain, R.K.1
  • 3
    • 0016707139 scopus 로고
    • Combination chemotherapy of Hodgkin's disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide versus MOPP
    • Bonadonna, G.; Zucali, R.; Monfardini, S.; De Lena, M.; Uslenghi, C. Combination chemotherapy of Hodgkin's disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide versus MOPP. Cancer, 1975, 36(1), 252-259.
    • (1975) Cancer , vol.36 , Issue.1 , pp. 252-259
    • Bonadonna, G.1    Zucali, R.2    Monfardini, S.3    De Lena, M.4    Uslenghi, C.5
  • 4
    • 0027461840 scopus 로고
    • Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer
    • Scheithauer, W.; Rosen, H.; Kornek, G. V.; Sebesta, C.; Depisch, D. Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer. BMJ, 1993, 306(6880), 752-755.
    • (1993) BMJ , vol.306 , Issue.6880 , pp. 752-755
    • Scheithauer, W.1    Rosen, H.2    Kornek, G.V.3    Sebesta, C.4    Depisch, D.5
  • 5
    • 68349139356 scopus 로고    scopus 로고
    • Gender differences in p-glycoprotein expression and function: Effects on drug disposition and outcome
    • Bebawy, M.; Chetty, M. Gender differences in p-glycoprotein expression and function: effects on drug disposition and outcome. Curr. Drug Metab., 2009, 10(4), 322-328.
    • (2009) Curr. Drug Metab , vol.10 , Issue.4 , pp. 322-328
    • Bebawy, M.1    Chetty, M.2
  • 6
    • 0031764330 scopus 로고    scopus 로고
    • Clinical relevance of transmembrane drug efflux as a mechanism of multidrug resistance
    • Bradshaw, D. M.; Arceci, R. J. Clinical relevance of transmembrane drug efflux as a mechanism of multidrug resistance. J. Clin. Oncol., 1998, 16(11), 3674-3690.
    • (1998) J. Clin. Oncol , vol.16 , Issue.11 , pp. 3674-3690
    • Bradshaw, D.M.1    Arceci, R.J.2
  • 7
    • 33846215616 scopus 로고    scopus 로고
    • A primer on the mechanics of P-glycoprotein the multidrug transporter
    • Hennessy, M.; Spiers, J.P. A primer on the mechanics of P-glycoprotein the multidrug transporter. Pharmacol. Res., 2007, 55(1), 1-15.
    • (2007) Pharmacol. Res , vol.55 , Issue.1 , pp. 1-15
    • Hennessy, M.1    Spiers, J.P.2
  • 8
    • 41549119415 scopus 로고    scopus 로고
    • Strategies to overcome or circumvent P-glycoprotein mediated multidrug resistance
    • Yuan, H.; Li, X.; Wu, J.; Li, J.; Qu, X.; Xu, W.; Tang, W. Strategies to overcome or circumvent P-glycoprotein mediated multidrug resistance. Curr. Med. Chem., 2008, 15(5), 470-476.
    • (2008) Curr. Med. Chem , vol.15 , Issue.5 , pp. 470-476
    • Yuan, H.1    Li, X.2    Wu, J.3    Li, J.4    Qu, X.5    Xu, W.6    Tang, W.7
  • 9
    • 33745605771 scopus 로고    scopus 로고
    • Nanotechnology: Intelligent design to treat complex disease
    • Couvreur, P.; Vauthier, C. Nanotechnology: intelligent design to treat complex disease. Pharmacol. Res., 2006, 23(7), 1417-1450.
    • (2006) Pharmacol. Res , vol.23 , Issue.7 , pp. 1417-1450
    • Couvreur, P.1    Vauthier, C.2
  • 10
    • 51049090204 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: An emerging treatment modality for cancer
    • Davis, M. E.; Chen, Z. G.; Shin, D. M. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug Discov., 2008, 7(9), 771-782.
    • (2008) Nat. Rev. Drug Discov , vol.7 , Issue.9 , pp. 771-782
    • Davis, M.E.1    Chen, Z.G.2    Shin, D.M.3
  • 13
    • 67249106291 scopus 로고    scopus 로고
    • Coadministration of Paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells
    • Ganta, S.; Amiji, M. Coadministration of Paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells. Mol. Pharm., 2009, 6(3), 928-939.
    • (2009) Mol. Pharm , vol.6 , Issue.3 , pp. 928-939
    • Ganta, S.1    Amiji, M.2
  • 14
    • 33845595490 scopus 로고    scopus 로고
    • Effect of transferrin receptor-targeted liposomal doxorubicin in P-glycoprotein-mediated drug resistant tumor cells
    • Kobayashi, T.; Ishida, T.; Okada, Y.; Ise, S.; Harashima, H.; Kiwada, H. Effect of transferrin receptor-targeted liposomal doxorubicin in P-glycoprotein-mediated drug resistant tumor cells. Int. J. Pharm., 2007, 329(1-2), 94-102.
    • (2007) Int. J. Pharm , vol.329 , Issue.1-2 , pp. 94-102
    • Kobayashi, T.1    Ishida, T.2    Okada, Y.3    Ise, S.4    Harashima, H.5    Kiwada, H.6
  • 15
    • 0344560656 scopus 로고    scopus 로고
    • Reversion of multidrug resistance by co-encapsulation of doxorubicin and cyclosporin A in polyalkylcyanoacrylate nanoparticles
    • Soma, C. E.; Dubernet, C.; Bentolila, D.; Benita, S.; Couvreur, P. Reversion of multidrug resistance by co-encapsulation of doxorubicin and cyclosporin A in polyalkylcyanoacrylate nanoparticles. Biomaterials, 2000, 21(1), 1-7.
    • (2000) Biomaterials , vol.21 , Issue.1 , pp. 1-7
    • Soma, C.E.1    Dubernet, C.2    Bentolila, D.3    Benita, S.4    Couvreur, P.5
  • 16
    • 0028308901 scopus 로고
    • Multidrug resistance in cancer chemotherapy
    • Patel, N.H.; Rothenberg, M. L. Multidrug resistance in cancer chemotherapy. Invest. New Drugs. 1994, 12(1), 1-13.
    • (1994) Invest. New Drugs , vol.12 , Issue.1 , pp. 1-13
    • Patel, N.H.1    Rothenberg, M.L.2
  • 17
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
    • Maeda, H. The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv. Enzyme Regul., 2001, 41, 189-207.
    • (2001) Adv. Enzyme Regul , vol.41 , pp. 189-207
    • Maeda, H.1
  • 18
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura, Y.; Maeda, H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res., 1986, 46(12 Pt 1), 6387-6392.
    • (1986) Cancer Res , vol.46 , Issue.12 PART 1 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 19
    • 2442691304 scopus 로고    scopus 로고
    • Tumor targeting based on the effect of enhanced permeability and retention (EPR) and the mechanism of receptor-mediated endocytosis (RME)
    • Tanaka, T.; Shiramoto, S.; Miyashita, M.; Fujishima, Y.; Kaneo, Y. Tumor targeting based on the effect of enhanced permeability and retention (EPR) and the mechanism of receptor-mediated endocytosis (RME). Int. J. Pharm., 2004, 277(1-2), 39-61.
    • (2004) Int. J. Pharm , vol.277 , Issue.1-2 , pp. 39-61
    • Tanaka, T.1    Shiramoto, S.2    Miyashita, M.3    Fujishima, Y.4    Kaneo, Y.5
  • 20
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carriers
    • Torchilin, V. P. Recent advances with liposomes as pharmaceutical carriers. Nat. Rev. Drug Discov., 2005, 4(2), 145-160.
    • (2005) Nat. Rev. Drug Discov , vol.4 , Issue.2 , pp. 145-160
    • Torchilin, V.P.1
  • 22
    • 0014982857 scopus 로고
    • Response of dogs to repeated intravenous injection of polyethylene glycol 4000 with notes on excretion and sensitization
    • Carpenter, C. P.; Woodside, M. D.; Kinkead, E. R.; King, J. M.; Sullivan, L. J. Response of dogs to repeated intravenous injection of polyethylene glycol 4000 with notes on excretion and sensitization. Toxicol. Appl. Pharmacol., 1971, 18(1), 35-40.
    • (1971) Toxicol. Appl. Pharmacol , vol.18 , Issue.1 , pp. 35-40
    • Carpenter, C.P.1    Woodside, M.D.2    Kinkead, E.R.3    King, J.M.4    Sullivan, L.J.5
  • 23
    • 13844318257 scopus 로고    scopus 로고
    • A reactive poly(ethylene glycol) layer to achieve specific surface plasmon resonance sensing with a high S/N ratio: The substantial role of a short underbrushed PEG layer in minimizing nonspecific adsorption
    • Uchida, K.; Otsuka, H.; Kaneko, M.; Kataoka, K.; Nagasaki, Y. A reactive poly(ethylene glycol) layer to achieve specific surface plasmon resonance sensing with a high S/N ratio: the substantial role of a short underbrushed PEG layer in minimizing nonspecific adsorption. Anal. Chem., 2005, 77(4), 1075-1080.
    • (2005) Anal. Chem , vol.77 , Issue.4 , pp. 1075-1080
    • Uchida, K.1    Otsuka, H.2    Kaneko, M.3    Kataoka, K.4    Nagasaki, Y.5
  • 24
    • 40449122796 scopus 로고    scopus 로고
    • Nanoparticle-mediated cellular response is size-dependent
    • Jiang, W.; Kim, B. Y. S.; Rutka, J. T.; Chan, W. C. W. Nanoparticle-mediated cellular response is size-dependent. Nat. Nanotechnol., 2008, 3(3), 145-150.
    • (2008) Nat. Nanotechnol , vol.3 , Issue.3 , pp. 145-150
    • Jiang, W.1    Kim, B.Y.S.2    Rutka, J.T.3    Chan, W.C.W.4
  • 25
    • 66449116301 scopus 로고    scopus 로고
    • Mediating tumor targeting efficiency of nanoparticles through design
    • Perrault, S. D.; Walkey, C.; Jennings, T.; Fischer, H. C.; Chan, W. C. Mediating tumor targeting efficiency of nanoparticles through design. Nano Lett., 2009, 9(5), 1909-1915.
    • (2009) Nano Lett , vol.9 , Issue.5 , pp. 1909-1915
    • Perrault, S.D.1    Walkey, C.2    Jennings, T.3    Fischer, H.C.4    Chan, W.C.5
  • 26
    • 0037681850 scopus 로고    scopus 로고
    • Pharmacokinetics of pegylated liposomal Doxorubicin: Review of animal and human studies
    • Gabizon, A.; Shmeeda, H.; Barenholz, Y. Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies. Clin. Pharmacokinet., 2003, 42(5), 419-436.
    • (2003) Clin. Pharmacokinet , vol.42 , Issue.5 , pp. 419-436
    • Gabizon, A.1    Shmeeda, H.2    Barenholz, Y.3
  • 27
    • 0035795022 scopus 로고    scopus 로고
    • PEGylated PLGA nanoparticles as protein carriers: Synthesis, preparation and biodistribution in rats
    • Li, Y.; Pei, Y.; Zhang, X.; Gu, Z.; Zhou, Z.; Yuan, W.; Zhou, J.; Zhu, J.; Gao, X., PEGylated PLGA nanoparticles as protein carriers: synthesis, preparation and biodistribution in rats. J. Control. Release, 2001, 71(2), 203-211.
    • (2001) J. Control. Release , vol.71 , Issue.2 , pp. 203-211
    • Li, Y.1    Pei, Y.2    Zhang, X.3    Gu, Z.4    Zhou, Z.5    Yuan, W.6    Zhou, J.7    Zhu, J.8    Gao, X.9
  • 30
    • 0033639085 scopus 로고    scopus 로고
    • Uptake of long-circulating immunoliposomes, directed against colon adenocarcinoma cells, by liver metastases of colon cancer
    • Kamps, J. A.; Koning, G. A.; Velinova, M. J.; Morselt, H. W.; Wilkens, M.; Gorter, A.; Donga, J.; Scherphof, G. L., Uptake of long-circulating immunoliposomes, directed against colon adenocarcinoma cells, by liver metastases of colon cancer. J. Drug Target, 2000, 8(4), 235-245.
    • (2000) J. Drug Target , vol.8 , Issue.4 , pp. 235-245
    • Kamps, J.A.1    Koning, G.A.2    Velinova, M.J.3    Morselt, H.W.4    Wilkens, M.5    Gorter, A.6    Donga, J.7    Scherphof, G.L.8
  • 31
    • 0037115543 scopus 로고    scopus 로고
    • Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs
    • Sapra, P.; Allen, T. M. Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs. Cancer Res., 2002, 62(24), 7190-7194.
    • (2002) Cancer Res , vol.62 , Issue.24 , pp. 7190-7194
    • Sapra, P.1    Allen, T.M.2
  • 32
    • 0032824375 scopus 로고    scopus 로고
    • Possibility of active targeting to tumor tissues with liposomes
    • Maruyama, K.; Ishida, O.; Takizawa, T.; Moribe, K. Possibility of active targeting to tumor tissues with liposomes. Adv. Drug Deliv. Rev., 1999, 40(1-2), 89-102.
    • (1999) Adv. Drug Deliv. Rev , vol.40 , Issue.1-2 , pp. 89-102
    • Maruyama, K.1    Ishida, O.2    Takizawa, T.3    Moribe, K.4
  • 33
    • 34547119332 scopus 로고    scopus 로고
    • Impact of single-chain Fv antibody fragment affinity on nanoparticle targeting of epidermal growth factor receptor-expressing tumor cells
    • Zhou, Y.; Drummond, D. C.; Zou, H.; Hayes, M. E.; Adams, G. P.; Kirpotin, D. B.; Marks, J. D. Impact of single-chain Fv antibody fragment affinity on nanoparticle targeting of epidermal growth factor receptor-expressing tumor cells. J. Mol. Biol., 2007, 371(4), 934-947.
    • (2007) J. Mol. Biol , vol.371 , Issue.4 , pp. 934-947
    • Zhou, Y.1    Drummond, D.C.2    Zou, H.3    Hayes, M.E.4    Adams, G.P.5    Kirpotin, D.B.6    Marks, J.D.7
  • 34
    • 0033641787 scopus 로고    scopus 로고
    • Liposome targeting to tumors using vitamin and growth factor receptors
    • Drummond, D. C.; Hong, K.; Park, J. W.; Benz, C. C.; Kirpotin, D. B. Liposome targeting to tumors using vitamin and growth factor receptors. Vitam. Horm., 2000, 60, 285-332.
    • (2000) Vitam. Horm , vol.60 , pp. 285-332
    • Drummond, D.C.1    Hong, K.2    Park, J.W.3    Benz, C.C.4    Kirpotin, D.B.5
  • 38
    • 0036063778 scopus 로고    scopus 로고
    • A tumor-homing peptide with a targeting specificity related to lymphatic vessels
    • Laakkonen, P.; Porkka, K.; Hoffman, J. A.; Ruoslahti, E. A tumor-homing peptide with a targeting specificity related to lymphatic vessels. Nat. Med., 2002, 8(7), 751-755.
    • (2002) Nat. Med , vol.8 , Issue.7 , pp. 751-755
    • Laakkonen, P.1    Porkka, K.2    Hoffman, J.A.3    Ruoslahti, E.4
  • 39
    • 33749265990 scopus 로고    scopus 로고
    • Multivalent effects of RGD peptides obtained by nanoparticle display
    • Montet, X.; Funovics, M.; Montet-Abou, K.; Weissleder, R.; Josephson, L. Multivalent effects of RGD peptides obtained by nanoparticle display. J. Med. Chem., 2006, 49(20), 6087-6093.
    • (2006) J. Med. Chem , vol.49 , Issue.20 , pp. 6087-6093
    • Montet, X.1    Funovics, M.2    Montet-Abou, K.3    Weissleder, R.4    Josephson, L.5
  • 40
    • 0029970607 scopus 로고    scopus 로고
    • Implications of acidic tumor microenvironment for neoplastic growth and cancer treatment: A computer analysis
    • Kraus, M.; Wolf, B. Implications of acidic tumor microenvironment for neoplastic growth and cancer treatment: a computer analysis. Tumour Biol., 1996, 17(3), 133-154.
    • (1996) Tumour Biol , vol.17 , Issue.3 , pp. 133-154
    • Kraus, M.1    Wolf, B.2
  • 41
    • 67049154133 scopus 로고    scopus 로고
    • A DNA nanomachine that maps spatial and temporal pH changes inside living cells
    • Modi, S.; Swetha, M. G.; Goswami, D.; Gupta, G. D.; Mayor, S.; Krishnan, Y. A DNA nanomachine that maps spatial and temporal pH changes inside living cells. Nat. Nanotechnol., 2009, 4, 325-330.
    • (2009) Nat. Nanotechnol , vol.4 , pp. 325-330
    • Modi, S.1    Swetha, M.G.2    Goswami, D.3    Gupta, G.D.4    Mayor, S.5    Krishnan, Y.6
  • 42
    • 1942534976 scopus 로고    scopus 로고
    • Smart delivery of antisense oligonucleotides by anionic pH-sensitive liposomes
    • Fattal, E.; Couvreur, P.; Dubernet, C., "Smart" delivery of antisense oligonucleotides by anionic pH-sensitive liposomes. Adv. Drug Deliv. Rev., 2004, 56(7), 931-946.
    • (2004) Adv. Drug Deliv. Rev , vol.56 , Issue.7 , pp. 931-946
    • Fattal, E.1    Couvreur, P.2    Dubernet, C.3
  • 43
    • 0037151421 scopus 로고    scopus 로고
    • Polymer based pH-sensitive carriers as a means to improve the cytoplasmic delivery of drugs
    • Roux, E.; Francis, M.; Winnik, F. M.; Leroux, J. C. Polymer based pH-sensitive carriers as a means to improve the cytoplasmic delivery of drugs. Int. J. Pharm. 2002, 242(1-2), 25-36.
    • (2002) Int. J. Pharm , vol.242 , Issue.1-2 , pp. 25-36
    • Roux, E.1    Francis, M.2    Winnik, F.M.3    Leroux, J.C.4
  • 44
    • 1942534972 scopus 로고    scopus 로고
    • On the formulation of pH-sensitive liposomes with long circulation times
    • Simoes, S.; Moreira, J. N.; Fonseca, C.; Duzgunes, N.; de Lima, M. C. On the formulation of pH-sensitive liposomes with long circulation times. Adv. Drug Deliv. Rev., 2004, 56(7), 947-965.
    • (2004) Adv. Drug Deliv. Rev , vol.56 , Issue.7 , pp. 947-965
    • Simoes, S.1    Moreira, J.N.2    Fonseca, C.3    Duzgunes, N.4    de Lima, M.C.5
  • 45
    • 56949105019 scopus 로고    scopus 로고
    • Recent progress in tumor pH targeting nanotechnology
    • Lee, E. S.; Gao, Z.; Bae, Y. H., Recent progress in tumor pH targeting nanotechnology. J. Control. Release, 2008, 132(3), 164-170.
    • (2008) J. Control. Release , vol.132 , Issue.3 , pp. 164-170
    • Lee, E.S.1    Gao, Z.2    Bae, Y.H.3
  • 46
    • 55849090997 scopus 로고    scopus 로고
    • Doxorubicin-loaded polymeric micelle overcomes multidrug resistance of cancer by double-targeting folate receptor and early endosomal pH
    • Kim, D.; Lee, E. S.; Oh, K. T.; Gao, Z. G.; Bae, Y. H., Doxorubicin-loaded polymeric micelle overcomes multidrug resistance of cancer by double-targeting folate receptor and early endosomal pH. Small, 2008, 4(11), 2043-2050.
    • (2008) Small , vol.4 , Issue.11 , pp. 2043-2050
    • Kim, D.1    Lee, E.S.2    Oh, K.T.3    Gao, Z.G.4    Bae, Y.H.5
  • 48
    • 67749143922 scopus 로고    scopus 로고
    • Expansile nanoparticles: Synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery system
    • Griset, A. P.; Walpole, J.; Liu, R.; Gaffey, A.; Colson, Y. L.; Grinstaff, M. W., Expansile nanoparticles: synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery system. J. Am. Chem. Soc., 2009, 131(7), 2469-2471.
    • (2009) J. Am. Chem. Soc , vol.131 , Issue.7 , pp. 2469-2471
    • Griset, A.P.1    Walpole, J.2    Liu, R.3    Gaffey, A.4    Colson, Y.L.5    Grinstaff, M.W.6
  • 49
    • 0031815720 scopus 로고    scopus 로고
    • Size of IgG-opsonized particles determines macrophage response during internalization
    • Koval, M.; Preiter, K.; Adles, C.; Stahl, P. D.; Steinberg, T. H. Size of IgG-opsonized particles determines macrophage response during internalization. Exp. Cell Res., 1998, 242(1), 265-273.
    • (1998) Exp. Cell Res , vol.242 , Issue.1 , pp. 265-273
    • Koval, M.1    Preiter, K.2    Adles, C.3    Stahl, P.D.4    Steinberg, T.H.5
  • 50
    • 1642575957 scopus 로고    scopus 로고
    • Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis
    • Rejman, J.; Oberle, V.; Zuhorn, I. S.; Hoekstra, D., Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis. Biochem. J., 2004, 377(Pt 1), 159-169.
    • (2004) Biochem. J , vol.377 , Issue.PART 1 , pp. 159-169
    • Rejman, J.1    Oberle, V.2    Zuhorn, I.S.3    Hoekstra, D.4
  • 52
    • 0036141740 scopus 로고    scopus 로고
    • effect on the intracellular drug localization
    • Intracellular uptake and trafficking of Pluronic micelles in drug-sensitive and MDR cells
    • Rapoport, N.; Marin, A.; Luo, Y.; Prestwich, G. D.; Muniruzzaman, M. D., Intracellular uptake and trafficking of Pluronic micelles in drug-sensitive and MDR cells: effect on the intracellular drug localization. J. Pharm. Sci., 2002, 91(1), 157-170.
    • (2002) J. Pharm. Sci , vol.91 , Issue.1 , pp. 157-170
    • Rapoport, N.1    Marin, A.2    Luo, Y.3    Prestwich, G.D.4    Muniruzzaman, M.D.5
  • 53
    • 24144490885 scopus 로고    scopus 로고
    • Enhanced antiproliferative activity of transferrin-conjugated paclitaxel-loaded nanoparticles is mediated via sustained intracellular drug retention
    • Sahoo, S. K.; Labhasetwar, V. Enhanced antiproliferative activity of transferrin-conjugated paclitaxel-loaded nanoparticles is mediated via sustained intracellular drug retention. Mol. Pharm., 2005, 2(5), 373-383.
    • (2005) Mol. Pharm , vol.2 , Issue.5 , pp. 373-383
    • Sahoo, S.K.1    Labhasetwar, V.2
  • 54
    • 0027414425 scopus 로고
    • Modulation of doxorubicin resistance in multidrug-resistant cells by liposomes
    • Thierry, A. R.; Vige, D.; Coughlin, S. S.; Belli, J. A.; Dritschilo, A.; Rahman, A. Modulation of doxorubicin resistance in multidrug-resistant cells by liposomes. FASEB J., 1993, 7(6), 572-579.
    • (1993) FASEB J , vol.7 , Issue.6 , pp. 572-579
    • Thierry, A.R.1    Vige, D.2    Coughlin, S.S.3    Belli, J.A.4    Dritschilo, A.5    Rahman, A.6
  • 55
    • 0023447098 scopus 로고
    • Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
    • Thiebaut, F.; Tsuruo, T.; Hamada, H.; Gottesman, M. M.; Pastan, I.; Willingham, M. C. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc. Natl. Acad. Sci. USA, 1987, 84(21), 7735-7738.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , Issue.21 , pp. 7735-7738
    • Thiebaut, F.1    Tsuruo, T.2    Hamada, H.3    Gottesman, M.M.4    Pastan, I.5    Willingham, M.C.6
  • 56
    • 0034710539 scopus 로고    scopus 로고
    • Patel, N. M.; Nozaki, S.; Shortle, N. H.; Bhat-Nakshatri, P.; Newton, T. R.; Rice, S.; Gelfanov, V.; Boswell, S. H.; Goulet, R. J., Jr.; Sledge, G. W., Jr.; Nakshatri, H. Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide. Oncogene, 2000, 19(36), 4159-4169.
    • Patel, N. M.; Nozaki, S.; Shortle, N. H.; Bhat-Nakshatri, P.; Newton, T. R.; Rice, S.; Gelfanov, V.; Boswell, S. H.; Goulet, R. J., Jr.; Sledge, G. W., Jr.; Nakshatri, H. Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide. Oncogene, 2000, 19(36), 4159-4169.
  • 57
    • 34250303805 scopus 로고    scopus 로고
    • Modulation of intracellular ceramide using polymeric nanoparticles to overcome multidrug resistance in cancer
    • van Vlerken, L. E.; Duan, Z.; Seiden, M. V.; Amiji, M. M. Modulation of intracellular ceramide using polymeric nanoparticles to overcome multidrug resistance in cancer. Cancer Res., 2007, 67(10), 4843-4850.
    • (2007) Cancer Res , vol.67 , Issue.10 , pp. 4843-4850
    • van Vlerken, L.E.1    Duan, Z.2    Seiden, M.V.3    Amiji, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.