Tumour targeted delivery of encapsulated dextran-doxorubicin conjugate using chitosan nanoparticles as carrier

Journal of Controlled Release

Volumn 74, Issue 1-3, 2001, Pages 317-323

  Mitra, S ^a   Gaur, U ^a   Ghosh, P C ^a   Maitra, A N ^a  

^a UNIVERSITY OF DELHI   (India)

Author keywords

Cancer therapy; Chitosan; Dextran doxorubicin; Hydrogel nanoparticles; Tumor targeting

Indexed keywords

CHITOSAN; DEXTRAN DOXORUBICIN CONJUGATE; DOXORUBICIN DERIVATIVE; DRUG CARRIER; NANOPARTICLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; BIOCOMPATIBILITY; BIODEGRADATION; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG PENETRATION; DRUG RETENTION; DRUG SAFETY; DRUG TARGETING; ENCAPSULATION; HYDROGEL; LIGHT SCATTERING; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOLID TUMOR; SURVIVAL TIME; TUMOR CELL; TUMOR REGRESSION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CHITIN; CHITOSAN; DEXTRANS; DOXORUBICIN; DRUG CARRIERS; EMULSIONS; LIGHT; MALE; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON; MICROSPHERES; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; PARTICLE SIZE; SCATTERING, RADIATION;

EID: 0035816156     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00342-X     Document Type: Conference Paper

References (17)

1. Adriamycin - Thoughts for the future
2. The anthracycline anti neoplastic drugs
3. Immunotoxicity of multiple dosing regimens of free doxorubicin and doxorubicin entrapped in cardiolipin liposomes
4. Studies on the myelosuppressive activity of doxorubicin entrapped in liposomes
5. Controlled release of drug model from N-[2-hydroxypropyl]methacrylamide copolymers
6. Increased therapeutic efficacy and reduced toxicity of doxorubicin linked to pyran copolymer via the side chain of the drug
7. Reduced toxicity of daunorubicin by conjugation to dextran
8. Higher antitumor efficacy of daunomycin when linked to dextran: In vivo and in vitro studies
9. Biodegradable long circulating polymeric nanospheres
10. Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo
11. Biodistribution of fluoresceinated dextran using novel nanoparticles evading reticuloendothelial system
12. Hydrogel nanoparticles: Their applications in drug delivery
13. Chitosan: A unique polysaccharide for drug delivery
14. Biomedical applications of nanotechnology - Implications for drug targeting and gene therapy
15. Drug targeting in cancer therapy: The magic bullet, what next?
16. Glutaraldehyde crosslinked chitosan microspheres as a long acting biodegradable drug delivery vehicle: Studies on the in vitro release of mitoxantrone and in vivo degradation of microspheres in rat muscle
17. Delivery of molecular and cellular medicines to solid tumors