메뉴 건너뛰기




Volumn 10, Issue 1, 2014, Pages 115-131

The future of blood-based biomarkers for Alzheimer's disease

(16)  Henriksen, Kim a   O'Bryant, Sid E b   Hampel, Harald c   Trojanowski, John Q d,n   Montine, Thomas J e   Jeromin, Andreas f   Blennow, Kaj g   Lönneborg, Anders h   Wyss Coray, Tony i   Soares, Holly j   Bazenet, Chantal k   Sjögren, Magnus h   Hu, William l   Lovestone, Simon k   Karsdal, Morten A a   Weiner, Michael W m  


Author keywords

Alzheimer's disease; Biomarkers; Blood; Plasma; Serum

Indexed keywords

AMYLOID BETA PROTEIN; AUTOANTIBODY; BIOLOGICAL MARKER; MICRORNA; TAU PROTEIN; TRANSCRIPTOME;

EID: 84891112523     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2013.01.013     Document Type: Review
Times cited : (252)

References (140)
  • 1
    • 80053971718 scopus 로고    scopus 로고
    • Current and emerging drug treatment options for Alzheimer's disease: A systematic review
    • N. Herrmann, S.A. Chau, I. Kircanski, and K.L. Lanctot Current and emerging drug treatment options for Alzheimer's disease: a systematic review Drugs 71 2011 2031 2065
    • (2011) Drugs , vol.71 , pp. 2031-2065
    • Herrmann, N.1    Chau, S.A.2    Kircanski, I.3    Lanctot, K.L.4
  • 2
    • 77951677787 scopus 로고    scopus 로고
    • Blood-based biomarkers of Alzheimer's disease: Challenging but feasible
    • M. Thambisetty, and S. Lovestone Blood-based biomarkers of Alzheimer's disease: challenging but feasible Biomark Med 4 2010 65 79
    • (2010) Biomark Med , vol.4 , pp. 65-79
    • Thambisetty, M.1    Lovestone, S.2
  • 3
    • 78149330220 scopus 로고    scopus 로고
    • Biomarkers in Alzheimer's disease drug development
    • K. Blennow Biomarkers in Alzheimer's disease drug development Nat Med 16 2010 1218 1222
    • (2010) Nat Med , vol.16 , pp. 1218-1222
    • Blennow, K.1
  • 4
    • 79956125839 scopus 로고    scopus 로고
    • Biomarkers in Alzheimer's disease drug development
    • J.L. Cummings Biomarkers in Alzheimer's disease drug development Alzheimers Dement 7 2011 e13 e44
    • (2011) Alzheimers Dement , vol.7
    • Cummings, J.L.1
  • 5
    • 77954239263 scopus 로고    scopus 로고
    • Biomarkers for Alzheimer's disease: Academic, industry and regulatory perspectives
    • H. Hampel, R. Frank, K. Broich, S.J. Teipel, R.G. Katz, and J. Hardy et al. Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives Nat Rev Drug Discov 9 2010 560 574
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 560-574
    • Hampel, H.1    Frank, R.2    Broich, K.3    Teipel, S.J.4    Katz, R.G.5    Hardy, J.6
  • 6
    • 80955137863 scopus 로고    scopus 로고
    • Blood-based biomarkers for Alzheimer's disease: Plasma Abeta40 and Abeta42, and genetic variants
    • R. Mayeux, and N. Schupf Blood-based biomarkers for Alzheimer's disease: plasma Abeta40 and Abeta42, and genetic variants Neurobiol Aging 32 2011 S10 S19
    • (2011) Neurobiol Aging , vol.32
    • Mayeux, R.1    Schupf, N.2
  • 7
    • 84855261953 scopus 로고    scopus 로고
    • Potential peripheral biomarkers for the diagnosis of Alzheimer's disease
    • S. Patel, R.J. Shah, P. Coleman, and M. Sabbagh Potential peripheral biomarkers for the diagnosis of Alzheimer's disease Int J Alzheimers Dis 2011 2011 572495
    • (2011) Int J Alzheimers Dis , vol.2011 , pp. 572495
    • Patel, S.1    Shah, R.J.2    Coleman, P.3    Sabbagh, M.4
  • 8
    • 53549094400 scopus 로고    scopus 로고
    • Biomarkers reflecting different facets of Alzheimer's disease
    • H. Zetterberg Biomarkers reflecting different facets of Alzheimer's disease Eur J Neurol 15 2008 1143 1144
    • (2008) Eur J Neurol , vol.15 , pp. 1143-1144
    • Zetterberg, H.1
  • 9
    • 84863645328 scopus 로고    scopus 로고
    • Will post-translational modifications of brain proteins provide novel serological markers for dementias?
    • Y. Wang, M.G. Sorensen, Q. Zheng, C. Zhang, M.A. Karsdal, and K. Henriksen Will post-translational modifications of brain proteins provide novel serological markers for dementias? Int J Alzheimers Dis 2012 2012 209409
    • (2012) Int J Alzheimers Dis , vol.2012 , pp. 209409
    • Wang, Y.1    Sorensen, M.G.2    Zheng, Q.3    Zhang, C.4    Karsdal, M.A.5    Henriksen, K.6
  • 11
    • 84858317522 scopus 로고    scopus 로고
    • US scientists discuss early detection and treatment of Alzheimer's disease
    • J.H. Tanne US scientists discuss early detection and treatment of Alzheimer's disease BMJ 344 2012 e1068
    • (2012) BMJ , vol.344 , pp. 1068
    • Tanne, J.H.1
  • 12
    • 77949423619 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
    • K. Blennow, H. Hampel, M. Weiner, and H. Zetterberg Cerebrospinal fluid and plasma biomarkers in Alzheimer disease Nat Rev Neurol 6 2010 131 144
    • (2010) Nat Rev Neurol , vol.6 , pp. 131-144
    • Blennow, K.1    Hampel, H.2    Weiner, M.3    Zetterberg, H.4
  • 14
    • 70449359683 scopus 로고    scopus 로고
    • CSF biomarkers: Pinpointing Alzheimer pathogenesis
    • N. Mattsson, K. Blennow, and H. Zetterberg CSF biomarkers: pinpointing Alzheimer pathogenesis Ann NY Acad Sci 1180 2009 28 35
    • (2009) Ann NY Acad Sci , vol.1180 , pp. 28-35
    • Mattsson, N.1    Blennow, K.2    Zetterberg, H.3
  • 16
    • 70449434560 scopus 로고    scopus 로고
    • Biological marker candidates of Alzheimer's disease in blood, plasma, and serum
    • P. Schneider, H. Hampel, and K. Buerger Biological marker candidates of Alzheimer's disease in blood, plasma, and serum CNS Neurosci Ther 15 2009 358 374
    • (2009) CNS Neurosci Ther , vol.15 , pp. 358-374
    • Schneider, P.1    Hampel, H.2    Buerger, K.3
  • 17
    • 84863188619 scopus 로고    scopus 로고
    • Effect of human cerebrospinal fluid sampling frequency on amyloid-beta levels
    • J. Li, D.A. Llano, T. Ellis, D. LeBlond, A. Bhathena, and S.S. Jhee et al. Effect of human cerebrospinal fluid sampling frequency on amyloid-beta levels Alzheimers Dement 8 2012 295 303
    • (2012) Alzheimers Dement , vol.8 , pp. 295-303
    • Li, J.1    Llano, D.A.2    Ellis, T.3    Leblond, D.4    Bhathena, A.5    Jhee, S.S.6
  • 18
    • 73549092137 scopus 로고    scopus 로고
    • Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease
    • J.C. Morris, C.M. Roe, E.A. Grant, D. Head, M. Storandt, and A.M. Goate et al. Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease Arch Neurol 66 2009 1469 1475
    • (2009) Arch Neurol , vol.66 , pp. 1469-1475
    • Morris, J.C.1    Roe, C.M.2    Grant, E.A.3    Head, D.4    Storandt, M.5    Goate, A.M.6
  • 19
  • 20
    • 56749112290 scopus 로고    scopus 로고
    • The future of amyloid-beta imaging: A tale of radionuclides and tracer proliferation
    • W.E. Klunk, and C.A. Mathis The future of amyloid-beta imaging: a tale of radionuclides and tracer proliferation Curr Opin Neurol 21 2008 683 687
    • (2008) Curr Opin Neurol , vol.21 , pp. 683-687
    • Klunk, W.E.1    Mathis, C.A.2
  • 21
    • 84863869296 scopus 로고    scopus 로고
    • Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-beta plaques: A prospective cohort study
    • C.M. Clark, M.J. Pontecorvo, T.G. Beach, B.J. Bedell, R.E. Coleman, and P.M. Doraiswamy et al. Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-beta plaques: a prospective cohort study Lancet Neurol 11 2012 669 678
    • (2012) Lancet Neurol , vol.11 , pp. 669-678
    • Clark, C.M.1    Pontecorvo, M.J.2    Beach, T.G.3    Bedell, B.J.4    Coleman, R.E.5    Doraiswamy, P.M.6
  • 22
    • 84863224067 scopus 로고    scopus 로고
    • Development of biomarkers to chart all Alzheimer's disease stages: The royal road to cutting the therapeutic Gordian Knot
    • H. Hampel, S. Lista, and Z.S. Khachaturian Development of biomarkers to chart all Alzheimer's disease stages: the royal road to cutting the therapeutic Gordian Knot Alzheimers Dement 8 2012 312 336
    • (2012) Alzheimers Dement , vol.8 , pp. 312-336
    • Hampel, H.1    Lista, S.2    Khachaturian, Z.S.3
  • 23
  • 24
    • 84874721353 scopus 로고    scopus 로고
    • Systematic Review of Clinical Research on Biomarkers for Pediatric Traumatic Brain Injury
    • L. Papa, M.M. Ramia, J.M. Kelly, S.S. Burks, A. Pawlowicz, and R.P. Berger Systematic Review of Clinical Research on Biomarkers for Pediatric Traumatic Brain Injury J. Neurotrauma 30 5 2013 324 338
    • (2013) J. Neurotrauma , vol.30 , Issue.5 , pp. 324-338
    • Papa, L.1    Ramia, M.M.2    Kelly, J.M.3    Burks, S.S.4    Pawlowicz, A.5    Berger, R.P.6
  • 25
    • 80054699616 scopus 로고    scopus 로고
    • Development of biomarkers for multiple sclerosis as a neurodegenerative disorder
    • U. Ziemann, M. Wahl, E. Hattingen, and H. Tumani Development of biomarkers for multiple sclerosis as a neurodegenerative disorder Prog Neurobiol 95 2011 670 685
    • (2011) Prog Neurobiol , vol.95 , pp. 670-685
    • Ziemann, U.1    Wahl, M.2    Hattingen, E.3    Tumani, H.4
  • 27
    • 84865683216 scopus 로고    scopus 로고
    • Brain amyloid imaging-FDA approval of florbetapir F18 injection
    • L. Yang, D. Rieves, and C. Ganley Brain amyloid imaging-FDA approval of florbetapir F18 injection N Engl J Med 367 2012 885 887
    • (2012) N Engl J Med , vol.367 , pp. 885-887
    • Yang, L.1    Rieves, D.2    Ganley, C.3
  • 28
    • 77952771512 scopus 로고    scopus 로고
    • Published by Alzheimer's Disease International Edited by: Martin Prince & Jim Jackson
    • World Alzheimer report 2009 2010 Published by Alzheimer's Disease International Edited by: Martin Prince & Jim Jackson
    • (2010) World Alzheimer Report 2009
  • 29
    • 84866106602 scopus 로고    scopus 로고
    • Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease
    • W.T. Hu, D.M. Holtzman, A.M. Fagan, L.M. Shaw, R. Perrin, and S.E. Arnold et al. Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease Neurology 79 2012 897 905
    • (2012) Neurology , vol.79 , pp. 897-905
    • Hu, W.T.1    Holtzman, D.M.2    Fagan, A.M.3    Shaw, L.M.4    Perrin, R.5    Arnold, S.E.6
  • 30
    • 84867340530 scopus 로고    scopus 로고
    • Plasma Biomarkers Associated with the Apolipoprotein e Genotype and Alzheimer Disease
    • H.D. Soares, W.Z. Potter, E. Pickering, M. Kuhn, F.W. Immermann, and D.M. Shera et al. Plasma Biomarkers Associated With the Apolipoprotein E Genotype and Alzheimer Disease Arch Neurol 69 10 2012 1310 1317
    • (2012) Arch Neurol , vol.69 , Issue.10 , pp. 1310-1317
    • Soares, H.D.1    Potter, W.Z.2    Pickering, E.3    Kuhn, M.4    Immermann, F.W.5    Shera, D.M.6
  • 31
    • 84875201745 scopus 로고    scopus 로고
    • The Role of Peripheral Inflammatory Markers in Dementia and Alzheimer's Disease: A Meta-Analysis
    • A. Koyama, J. O'Brien, J. Weuve, D. Blacker, A.L. Metti, and K. Yaffe The Role of Peripheral Inflammatory Markers in Dementia and Alzheimer's Disease: A Meta-Analysis J Gerontol A Biol Sci Med Sci 68 4 2013 433 440
    • (2013) J Gerontol A Biol Sci Med Sci , vol.68 , Issue.4 , pp. 433-440
    • Koyama, A.1    O'Brien, J.2    Weuve, J.3    Blacker, D.4    Metti, A.L.5    Yaffe, K.6
  • 32
    • 33746310315 scopus 로고    scopus 로고
    • Alzheimer's disease
    • DOI 10.1016/S0140-6736(06)69113-7, PII S0140673606691137
    • K. Blennow, M.J. de Leon, and H. Zetterberg Alzheimer's disease Lancet 368 2006 387 403 (Pubitemid 44108123)
    • (2006) Lancet , vol.368 , Issue.9533 , pp. 387-403
    • Blennow, K.1    De Leon, M.J.2    Zetterberg, H.3
  • 33
    • 80051669619 scopus 로고    scopus 로고
    • The projected effect of risk factor reduction on Alzheimer's disease prevalence
    • D.E. Barnes, and K. Yaffe The projected effect of risk factor reduction on Alzheimer's disease prevalence Lancet Neurol 10 2011 819 828
    • (2011) Lancet Neurol , vol.10 , pp. 819-828
    • Barnes, D.E.1    Yaffe, K.2
  • 34
    • 0034764622 scopus 로고    scopus 로고
    • Clinical and pathological diagnosis of frontotemporal dementia: Report of the work group on Frontotemporal Dementia and Pick's Disease
    • G.M. McKhann, M.S. Albert, M. Grossman, B. Miller, D. Dickson, and J.Q. Trojanowski Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease Arch Neurol 58 2001 1803 1809 (Pubitemid 33044246)
    • (2001) Archives of Neurology , vol.58 , Issue.11 , pp. 1803-1809
    • McKhann, G.M.1    Albert, M.S.2    Grossman, M.3    Miller, B.4    Dickson, D.5    Trojanowski, J.Q.6
  • 35
    • 84857543329 scopus 로고    scopus 로고
    • Nanotechnologies: A strategy to overcome blood-brain barrier
    • G.D. Rosa, G. Salzano, M. Caraglia, and A. Abbruzzese Nanotechnologies: a strategy to overcome blood-brain barrier Curr Drug Metab 13 1 2012 61 69
    • (2012) Curr Drug Metab , vol.13 , Issue.1 , pp. 61-69
    • Rosa, G.D.1    Salzano, G.2    Caraglia, M.3    Abbruzzese, A.4
  • 37
    • 84855866955 scopus 로고    scopus 로고
    • Oxidative stress and beta-amyloid protein in Alzheimer's disease
    • Z. Cai, B. Zhao, and A. Ratka Oxidative stress and beta-amyloid protein in Alzheimer's disease Neuromolecular Med 13 2011 223 250
    • (2011) Neuromolecular Med , vol.13 , pp. 223-250
    • Cai, Z.1    Zhao, B.2    Ratka, A.3
  • 41
    • 84886747916 scopus 로고    scopus 로고
    • Translational proteomics in Alzheimer's disease and related disorders
    • R. Ghidoni, A. Paterlini, and L. Benussi Translational proteomics in Alzheimer's disease and related disorders Clin Biochem 46 6 2013 480 486
    • (2013) Clin Biochem , vol.46 , Issue.6 , pp. 480-486
    • Ghidoni, R.1    Paterlini, A.2    Benussi, L.3
  • 42
    • 77954579179 scopus 로고    scopus 로고
    • Biochemical markers identify influences on bone and cartilage degradation in osteoarthritis - The effect of sex, Kellgren-Lawrence (KL) score, Body Mass Index (BMI), oral salmon calcitonin (sCT) treatment and diurnal variation BMC
    • M.A. Karsdal, I. Byrjalsen, A.C. Bay-Jensen, K. Henriksen, B.J. Riis, and C. Christiansen Biochemical markers identify influences on bone and cartilage degradation in osteoarthritis - the effect of sex, Kellgren-Lawrence (KL) score, Body Mass Index (BMI), oral salmon calcitonin (sCT) treatment and diurnal variation BMC Musculoskelet Disord 11 2010 125
    • (2010) Musculoskelet Disord , vol.11 , pp. 125
    • Karsdal, M.A.1    Byrjalsen, I.2    Bay-Jensen, A.C.3    Henriksen, K.4    Riis, B.J.5    Christiansen, C.6
  • 43
    • 77953706518 scopus 로고    scopus 로고
    • Novel combinations of Post-Translational Modification (PTM) neo-epitopes provide tissue-specific biochemical markers-are they the cause or the consequence of the disease?
    • M.A. Karsdal, K. Henriksen, D.J. Leeming, T. Woodworth, E. Vassiliadis, and A.C. Bay-Jensen Novel combinations of Post-Translational Modification (PTM) neo-epitopes provide tissue-specific biochemical markers-are they the cause or the consequence of the disease? Clin Biochem 43 2010 793 804
    • (2010) Clin Biochem , vol.43 , pp. 793-804
    • Karsdal, M.A.1    Henriksen, K.2    Leeming, D.J.3    Woodworth, T.4    Vassiliadis, E.5    Bay-Jensen, A.C.6
  • 44
    • 82155192252 scopus 로고    scopus 로고
    • Biochemical markers of ongoing joint damage in rheumatoid arthritis-current and future applications, limitations and opportunities
    • M.A. Karsdal, T. Woodworth, K. Henriksen, W.P. Maksymowych, H. Genant, and P. Vergnaud et al. Biochemical markers of ongoing joint damage in rheumatoid arthritis-current and future applications, limitations and opportunities Arthritis Res Ther 13 2011 215
    • (2011) Arthritis Res Ther , vol.13 , pp. 215
    • Karsdal, M.A.1    Woodworth, T.2    Henriksen, K.3    Maksymowych, W.P.4    Genant, H.5    Vergnaud, P.6
  • 45
    • 77954510398 scopus 로고    scopus 로고
    • Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease
    • M. Thambisetty, A. Simmons, L. Velayudhan, A. Hye, J. Campbell, and Y. Zhang et al. Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease Arch Gen Psychiatry 67 2010 739 748
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 739-748
    • Thambisetty, M.1    Simmons, A.2    Velayudhan, L.3    Hye, A.4    Campbell, J.5    Zhang, Y.6
  • 49
    • 78651372043 scopus 로고    scopus 로고
    • Proteome-based plasma markers of brain amyloid-beta deposition in non-demented older individuals
    • M. Thambisetty, R. Tripaldi, J. Riddoch-Contreras, A. Hye, Y. An, and J. Campbell et al. Proteome-based plasma markers of brain amyloid-beta deposition in non-demented older individuals J Alzheimers Dis 22 2010 1099 1109
    • (2010) J Alzheimers Dis , vol.22 , pp. 1099-1109
    • Thambisetty, M.1    Tripaldi, R.2    Riddoch-Contreras, J.3    Hye, A.4    An, Y.5    Campbell, J.6
  • 50
    • 78049448191 scopus 로고    scopus 로고
    • SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease
    • C. Cruchaga, J.S. Kauwe, K. Mayo, N. Spiegel, S. Bertelsen, and P. Nowotny et al. SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease PLoS Genet 6 2012
    • (2012) PLoS Genet , vol.6
    • Cruchaga, C.1    Kauwe, J.S.2    Mayo, K.3    Spiegel, N.4    Bertelsen, S.5    Nowotny, P.6
  • 52
    • 66149103673 scopus 로고    scopus 로고
    • Biochemical markers and the FDA Critical Path: How biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development
    • M.A. Karsdal, K. Henriksen, D.J. Leeming, P. Mitchell, K. Duffin, and N. Barascuk et al. Biochemical markers and the FDA Critical Path: how biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development Biomarkers 14 2009 181 202
    • (2009) Biomarkers , vol.14 , pp. 181-202
    • Karsdal, M.A.1    Henriksen, K.2    Leeming, D.J.3    Mitchell, P.4    Duffin, K.5    Barascuk, N.6
  • 53
    • 84873155319 scopus 로고    scopus 로고
    • Biological and methodical challenges of blood-based proteomics in the field of neurological research
    • S. Lista, F. Faltraco, and H. Hampel Biological and methodical challenges of blood-based proteomics in the field of neurological research Prog Neurobiol 101-102 2013 18 34
    • (2013) Prog Neurobiol , vol.101-102 , pp. 18-34
    • Lista, S.1    Faltraco, F.2    Hampel, H.3
  • 55
    • 80054042479 scopus 로고    scopus 로고
    • Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome
    • M. Britschgi, K. Rufibach, S.L. Huang, C.M. Clark, J.A. Kaye, and G. Li et al. Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome Mol Cell Proteomics 10 2011 M111
    • (2011) Mol Cell Proteomics , vol.10 , pp. 111
    • Britschgi, M.1    Rufibach, K.2    Huang, S.L.3    Clark, C.M.4    Kaye, J.A.5    Li, G.6
  • 56
    • 70449435231 scopus 로고    scopus 로고
    • Identifying early markers of Alzheimer's disease using quantitative multiplex proteomic immunoassay panels
    • H.D. Soares, Y. Chen, M. Sabbagh, A. Roher, E. Schrijvers, and M. Breteler Identifying early markers of Alzheimer's disease using quantitative multiplex proteomic immunoassay panels Ann NY Acad Sci 1180 2009 56 67
    • (2009) Ann NY Acad Sci , vol.1180 , pp. 56-67
    • Soares, H.D.1    Chen, Y.2    Sabbagh, M.3    Roher, A.4    Schrijvers, E.5    Breteler, M.6
  • 57
    • 84855975889 scopus 로고    scopus 로고
    • Evaluation of a previously suggested plasma biomarker panel to identify Alzheimer's disease
    • M. Bjorkqvist, M. Ohlsson, L. Minthon, and O. Hansson Evaluation of a previously suggested plasma biomarker panel to identify Alzheimer's disease PLoS One 7 2012 e29868
    • (2012) PLoS One , vol.7 , pp. 29868
    • Bjorkqvist, M.1    Ohlsson, M.2    Minthon, L.3    Hansson, O.4
  • 58
    • 84867339786 scopus 로고    scopus 로고
    • Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease
    • J.D. Doecke, S.M. Laws, N.G. Faux, W. Wilson, S.C. Burnham, and C.P. Lam et al. Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease Arch Neurol 69 10 2012 1318 1325
    • (2012) Arch Neurol , vol.69 , Issue.10 , pp. 1318-1325
    • Doecke, J.D.1    Laws, S.M.2    Faux, N.G.3    Wilson, W.4    Burnham, S.C.5    Lam, C.P.6
  • 59
    • 82855163989 scopus 로고    scopus 로고
    • A blood-based screening tool for Alzheimer's disease that spans serum and plasma: Findings from TARC and ADNI
    • S.E. O'Bryant, G. Xiao, R. Barber, R. Huebinger, K. Wilhelmsen, and M. Edwards et al. A blood-based screening tool for Alzheimer's disease that spans serum and plasma: findings from TARC and ADNI PLoS One 6 2011 e28092
    • (2011) PLoS One , vol.6 , pp. 28092
    • O'Bryant, S.E.1    Xiao, G.2    Barber, R.3    Huebinger, R.4    Wilhelmsen, K.5    Edwards, M.6
  • 60
    • 84891132579 scopus 로고    scopus 로고
    • Evaluation of Plasma Proteomic Data for Alzheimer Disease State Classification and for the Prediction of Progression from Mild Cognitive Impairment to Alzheimer Disease
    • [Epub ahead of print]
    • D.A. Llano, V. Devanarayan, and A.J. Simon Evaluation of Plasma Proteomic Data for Alzheimer Disease State Classification and for the Prediction of Progression From Mild Cognitive Impairment to Alzheimer Disease Alzheimer Dis Assoc Disord 2012 [Epub ahead of print]
    • (2012) Alzheimer Dis Assoc Disord
    • Llano, D.A.1    Devanarayan, V.2    Simon, A.J.3
  • 63
    • 67349279244 scopus 로고    scopus 로고
    • Blood-based microcirculation markers in Alzheimer's disease-diagnostic value of midregional pro-atrial natriuretic peptide/C-terminal endothelin-1 precursor fragment ratio
    • K. Buerger, A. Ernst, M. Ewers, O. Uspenskaya, M. Omerovic, and N.G. Morgenthaler et al. Blood-based microcirculation markers in Alzheimer's disease-diagnostic value of midregional pro-atrial natriuretic peptide/C-terminal endothelin-1 precursor fragment ratio Biol Psychiatry 65 2009 979 984
    • (2009) Biol Psychiatry , vol.65 , pp. 979-984
    • Buerger, K.1    Ernst, A.2    Ewers, M.3    Uspenskaya, O.4    Omerovic, M.5    Morgenthaler, N.G.6
  • 64
    • 79955519721 scopus 로고    scopus 로고
    • Prediction of Alzheimer's disease using midregional proadrenomedullin and midregional proatrial natriuretic peptide: A retrospective analysis of 134 patients with mild cognitive impairment
    • K. Buerger, O. Uspenskaya, O. Hartmann, O. Hansson, L. Minthon, and K. Blennow et al. Prediction of Alzheimer's disease using midregional proadrenomedullin and midregional proatrial natriuretic peptide: a retrospective analysis of 134 patients with mild cognitive impairment J Clin Psychiatry 72 2011 556 563
    • (2011) J Clin Psychiatry , vol.72 , pp. 556-563
    • Buerger, K.1    Uspenskaya, O.2    Hartmann, O.3    Hansson, O.4    Minthon, L.5    Blennow, K.6
  • 65
    • 84867722073 scopus 로고    scopus 로고
    • Characterization of plasma beta-secretase (BACE1) activity and soluble amyloid precursor proteins as potential biomarkers for Alzheimer's disease
    • G. Wu, S. Sankaranarayanan, J. Wong, K. Tugusheva, M.S. Michener, and X. Shi et al. Characterization of plasma beta-secretase (BACE1) activity and soluble amyloid precursor proteins as potential biomarkers for Alzheimer's disease J Neurosci Res 90 2012 2247 2258
    • (2012) J Neurosci Res , vol.90 , pp. 2247-2258
    • Wu, G.1    Sankaranarayanan, S.2    Wong, J.3    Tugusheva, K.4    Michener, M.S.5    Shi, X.6
  • 66
    • 79955051063 scopus 로고    scopus 로고
    • Linking lipids to Alzheimer's disease: Cholesterol and beyond
    • P.G. Di, and T.W. Kim Linking lipids to Alzheimer's disease: cholesterol and beyond Nat Rev Neurosci 12 2011 284 296
    • (2011) Nat Rev Neurosci , vol.12 , pp. 284-296
    • Di, P.G.1    Kim, T.W.2
  • 67
    • 84855596356 scopus 로고    scopus 로고
    • Lipidomics of Alzheimer's disease: Current status
    • P.L. Wood Lipidomics of Alzheimer's disease: current status Alzheimers Res Ther 4 2012 5
    • (2012) Alzheimers Res Ther , vol.4 , pp. 5
    • Wood, P.L.1
  • 68
    • 79960114429 scopus 로고    scopus 로고
    • Metabolomics in early Alzheimer's disease: Identification of altered plasma sphingolipidome using shotgun lipidomics
    • X. Han, S. Rozen, S.H. Boyle, C. Hellegers, H. Cheng, and J.R. Burke et al. Metabolomics in early Alzheimer's disease: identification of altered plasma sphingolipidome using shotgun lipidomics PLoS One 6 2011 e21643
    • (2011) PLoS One , vol.6 , pp. 21643
    • Han, X.1    Rozen, S.2    Boyle, S.H.3    Hellegers, C.4    Cheng, H.5    Burke, J.R.6
  • 69
    • 81855168404 scopus 로고    scopus 로고
    • Plasma Sphingomyelins are Associated with Cognitive Progression in Alzheimer's Disease
    • M.M. Mielke, N.J. Haughey, V.V. Bandaru, D.D. Weinberg, E. Darby, and N. Zaidi et al. Plasma Sphingomyelins are Associated with Cognitive Progression in Alzheimer's Disease J Alzheimers Dis 27 2 2011 259 269
    • (2011) J Alzheimers Dis , vol.27 , Issue.2 , pp. 259-269
    • Mielke, M.M.1    Haughey, N.J.2    Bandaru, V.V.3    Weinberg, D.D.4    Darby, E.5    Zaidi, N.6
  • 70
  • 72
    • 84867511423 scopus 로고    scopus 로고
    • Validation of AclarusDx, a Blood-Based Transcriptomic Signature for the Diagnosis of Alzheimer's Disease
    • P. Fehlbaum-Beurdeley, O. Sol, L. Desire, J. Touchon, T. Dantoine, and M. Vercelletto et al. Validation of AclarusDx, a Blood-Based Transcriptomic Signature for the Diagnosis of Alzheimer's Disease J Alzheimers Dis 32 2012 169 181
    • (2012) J Alzheimers Dis , vol.32 , pp. 169-181
    • Fehlbaum-Beurdeley, P.1    Sol, O.2    Desire, L.3    Touchon, J.4    Dantoine, T.5    Vercelletto, M.6
  • 74
    • 84862861561 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood
    • K. Lunnon, Z. Ibrahim, P. Proitsi, A. Lourdusamy, S. Newhouse, and M. Sattlecker et al. Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood J Alzheimers Dis 30 2012 685 710
    • (2012) J Alzheimers Dis , vol.30 , pp. 685-710
    • Lunnon, K.1    Ibrahim, Z.2    Proitsi, P.3    Lourdusamy, A.4    Newhouse, S.5    Sattlecker, M.6
  • 75
    • 49949108971 scopus 로고    scopus 로고
    • Age-specific epigenetic drift in late-onset Alzheimer's disease
    • S.C. Wang, B. Oelze, and A. Schumacher Age-specific epigenetic drift in late-onset Alzheimer's disease PLoS One 3 2008 e2698
    • (2008) PLoS One , vol.3 , pp. 2698
    • Wang, S.C.1    Oelze, B.2    Schumacher, A.3
  • 77
    • 71549154065 scopus 로고    scopus 로고
    • Comparisons of telomere lengths in peripheral blood and cerebellum in Alzheimer's disease
    • J.N. Lukens, D.V. Van, C.M. Clark, S.X. Xie, and F.B. Johnson Comparisons of telomere lengths in peripheral blood and cerebellum in Alzheimer's disease Alzheimers Dement 5 2009 463 469
    • (2009) Alzheimers Dement , vol.5 , pp. 463-469
    • Lukens, J.N.1    Van, D.V.2    Clark, C.M.3    Xie, S.X.4    Johnson, F.B.5
  • 78
    • 84856211181 scopus 로고    scopus 로고
    • Telomere length is age-dependent and reduced in monocytes of Alzheimer patients
    • T. Hochstrasser, J. Marksteiner, and C. Humpel Telomere length is age-dependent and reduced in monocytes of Alzheimer patients Exp Gerontol 47 2012 160 163
    • (2012) Exp Gerontol , vol.47 , pp. 160-163
    • Hochstrasser, T.1    Marksteiner, J.2    Humpel, C.3
  • 81
    • 77956922920 scopus 로고    scopus 로고
    • Autoantibodies in patients with Alzheimer's disease: Pathogenetic role and potential use as biomarkers of disease progression
    • T. Colasanti, C. Barbati, G. Rosano, W. Malorni, and E. Ortona Autoantibodies in patients with Alzheimer's disease: pathogenetic role and potential use as biomarkers of disease progression Autoimmun Rev 9 2010 807 811
    • (2010) Autoimmun Rev , vol.9 , pp. 807-811
    • Colasanti, T.1    Barbati, C.2    Rosano, G.3    Malorni, W.4    Ortona, E.5
  • 82
    • 71849100252 scopus 로고    scopus 로고
    • Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: A population-based study
    • K.A. Gustaw-Rothenberg, S.L. Siedlak, D.J. Bonda, A. Lerner, M. Tabaton, and G. Perry et al. Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study Exp Gerontol 45 2010 47 52
    • (2010) Exp Gerontol , vol.45 , pp. 47-52
    • Gustaw-Rothenberg, K.A.1    Siedlak, S.L.2    Bonda, D.J.3    Lerner, A.4    Tabaton, M.5    Perry, G.6
  • 83
    • 84866015162 scopus 로고    scopus 로고
    • Antigen-Bound and Free beta-Amyloid Autoantibodies in Serum of Healthy Adults
    • M. Maftei, F. Thurm, V.M. Leirer, C.A. von Arnim, and T. Elbert et al. Antigen-Bound and Free beta-Amyloid Autoantibodies in Serum of Healthy Adults PLoS One 7 2012 e44516
    • (2012) PLoS One , vol.7 , pp. 44516
    • Maftei, M.1    Thurm, F.2    Leirer, V.M.3    Von Arnim, C.A.4    Elbert, T.5
  • 84
    • 79961059917 scopus 로고    scopus 로고
    • Diagnosis of Alzheimer's disease based on disease-specific autoantibody profiles in human sera
    • E. Nagele, M. Han, C. Demarshall, B. Belinka, and R. Nagele Diagnosis of Alzheimer's disease based on disease-specific autoantibody profiles in human sera PLoS One 6 2011 e23112
    • (2011) PLoS One , vol.6 , pp. 23112
    • Nagele, E.1    Han, M.2    Demarshall, C.3    Belinka, B.4    Nagele, R.5
  • 85
    • 84860369464 scopus 로고    scopus 로고
    • Blood serum miRNA: Non-invasive biomarkers for Alzheimer's disease
    • H. Geekiyanage, G.A. Jicha, P.T. Nelson, and C. Chan Blood serum miRNA: non-invasive biomarkers for Alzheimer's disease Exp Neurol 235 2012 491 496
    • (2012) Exp Neurol , vol.235 , pp. 491-496
    • Geekiyanage, H.1    Jicha, G.A.2    Nelson, P.T.3    Chan, C.4
  • 88
    • 0033975837 scopus 로고    scopus 로고
    • Plasma and cerebrospinal fluid levels of amyloid β proteins 1-40 and 1- 42 in Alzheimer disease
    • P.D. Mehta, T. Pirttila, S.P. Mehta, E.A. Sersen, P.S. Aisen, and H.M. Wisniewski Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease Arch Neurol 57 2000 100 105 (Pubitemid 30027637)
    • (2000) Archives of Neurology , vol.57 , Issue.1 , pp. 100-105
    • Mehta, P.D.1    Pirttila, T.2    Mehta, S.P.3    Sersen, E.A.4    Aisen, P.S.5    Wisniewski, H.M.6
  • 89
    • 84863800460 scopus 로고    scopus 로고
    • Plasma amyloid-beta as a predictor of dementia and cognitive decline: A systematic review and meta-analysis
    • A. Koyama, O.I. Okereke, T. Yang, D. Blacker, D.J. Selkoe, and F. Grodstein Plasma amyloid-beta as a predictor of dementia and cognitive decline: a systematic review and meta-analysis Arch Neurol 69 2012 824 831
    • (2012) Arch Neurol , vol.69 , pp. 824-831
    • Koyama, A.1    Okereke, O.I.2    Yang, T.3    Blacker, D.4    Selkoe, D.J.5    Grodstein, F.6
  • 90
    • 77952542382 scopus 로고    scopus 로고
    • Biological markers of amyloid beta-related mechanisms in Alzheimer's disease
    • H. Hampel, Y. Shen, D.M. Walsh, P. Aisen, L.M. Shaw, and H. Zetterberg et al. Biological markers of amyloid beta-related mechanisms in Alzheimer's disease Exp Neurol 223 2012 334 346
    • (2012) Exp Neurol , vol.223 , pp. 334-346
    • Hampel, H.1    Shen, Y.2    Walsh, D.M.3    Aisen, P.4    Shaw, L.M.5    Zetterberg, H.6
  • 91
    • 84863489190 scopus 로고    scopus 로고
    • Longitudinal plasma amyloid beta as a biomarker of Alzheimer's disease
    • R.A. Rissman, J.Q. Trojanowski, L.M. Shaw, and P.S. Aisen Longitudinal plasma amyloid beta as a biomarker of Alzheimer's disease J Neural Transm 119 2012 843 850
    • (2012) J Neural Transm , vol.119 , pp. 843-850
    • Rissman, R.A.1    Trojanowski, J.Q.2    Shaw, L.M.3    Aisen, P.S.4
  • 93
  • 95
    • 60549107033 scopus 로고    scopus 로고
    • A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease
    • W. Xia, T. Yang, G. Shankar, I.M. Smith, Y. Shen, and D.M. Walsh et al. A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease Arch Neurol 66 2009 190 199
    • (2009) Arch Neurol , vol.66 , pp. 190-199
    • Xia, W.1    Yang, T.2    Shankar, G.3    Smith, I.M.4    Shen, Y.5    Walsh, D.M.6
  • 96
    • 79961023795 scopus 로고    scopus 로고
    • Serum tau protein as a marker for the diagnosis of Creutzfeldt-Jakob disease
    • M. Noguchi-Shinohara, T. Hamaguchi, I. Nozaki, K. Sakai, and M. Yamada Serum tau protein as a marker for the diagnosis of Creutzfeldt-Jakob disease J Neurol 258 2011 1464 1468
    • (2011) J Neurol , vol.258 , pp. 1464-1468
    • Noguchi-Shinohara, M.1    Hamaguchi, T.2    Nozaki, I.3    Sakai, K.4    Yamada, M.5
  • 98
    • 77951024518 scopus 로고    scopus 로고
    • Tau proteins in serum predict outcome after severe traumatic brain injury
    • P.C. Liliang, C.L. Liang, H.C. Weng, K. Lu, K.W. Wang, and H.J. Chen et al. Tau proteins in serum predict outcome after severe traumatic brain injury J Surg Res 160 2010 302 307
    • (2010) J Surg Res , vol.160 , pp. 302-307
    • Liliang, P.C.1    Liang, C.L.2    Weng, H.C.3    Lu, K.4    Wang, K.W.5    Chen, H.J.6
  • 99
    • 84875054575 scopus 로고    scopus 로고
    • Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: Results of a pilot study
    • J. Randall, E. Mortberg, G.K. Provuncher, D.R. Fournier, D.C. Duffy, and S. Rubertsson et al. Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: Results of a pilot study Resuscitation 84 3 2013 351 356
    • (2013) Resuscitation , vol.84 , Issue.3 , pp. 351-356
    • Randall, J.1    Mortberg, E.2    Provuncher, G.K.3    Fournier, D.R.4    Duffy, D.C.5    Rubertsson, S.6
  • 102
    • 84856638194 scopus 로고    scopus 로고
    • BACE1 inhibition induces a specific cerebrospinal fluid beta-amyloid pattern that identifies drug effects in the central nervous system
    • N. Mattsson, L. Rajendran, H. Zetterberg, M. Gustavsson, U. Andreasson, and M. Olsson et al. BACE1 inhibition induces a specific cerebrospinal fluid beta-amyloid pattern that identifies drug effects in the central nervous system PLoS One 7 2012 e31084
    • (2012) PLoS One , vol.7 , pp. 31084
    • Mattsson, N.1    Rajendran, L.2    Zetterberg, H.3    Gustavsson, M.4    Andreasson, U.5    Olsson, M.6
  • 103
    • 79957996565 scopus 로고    scopus 로고
    • Amyloid {beta}-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation
    • J. Reifert, D. Hartung-Cranston, and S.C. Feinstein Amyloid {beta}-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation J Biol Chem 286 2011 20797 20811
    • (2011) J Biol Chem , vol.286 , pp. 20797-20811
    • Reifert, J.1    Hartung-Cranston, D.2    Feinstein, S.C.3
  • 106
    • 49349104833 scopus 로고    scopus 로고
    • Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease
    • T.T. Rohn Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease Brain Res 1228 2008 189 198
    • (2008) Brain Res , vol.1228 , pp. 189-198
    • Rohn, T.T.1
  • 108
    • 61549111872 scopus 로고    scopus 로고
    • Alpha-Synuclein and neuronal cell death
    • M.R. Cookson alpha-Synuclein and neuronal cell death Mol Neurodegener 4 2009 9
    • (2009) Mol Neurodegener , vol.4 , pp. 9
    • Cookson, M.R.1
  • 109
    • 77951060145 scopus 로고    scopus 로고
    • Proteases and proteolysis in Alzheimer disease: A multifactorial view on the disease process
    • B. De Strooper Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process Physiol Rev 90 2010 465 494
    • (2010) Physiol Rev , vol.90 , pp. 465-494
    • De Strooper, B.1
  • 110
    • 84861235844 scopus 로고    scopus 로고
    • Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells
    • S. Brunholz, S. Sisodia, A. Lorenzo, C. Deyts, S. Kins, and G. Morfini Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells Exp Brain Res 217 3-4 2012 353 364
    • (2012) Exp Brain Res , vol.217 , Issue.34 , pp. 353-364
    • Brunholz, S.1    Sisodia, S.2    Lorenzo, A.3    Deyts, C.4    Kins, S.5    Morfini, G.6
  • 111
    • 84862897184 scopus 로고    scopus 로고
    • The role of APP proteolytic processing in lipid metabolism
    • M.O. Grimm, T.L. Rothhaar, and T. Hartmann The role of APP proteolytic processing in lipid metabolism Exp Brain Res 217 3-4 2012 365 375
    • (2012) Exp Brain Res , vol.217 , Issue.34 , pp. 365-375
    • Grimm, M.O.1    Rothhaar, T.L.2    Hartmann, T.3
  • 112
    • 78149391828 scopus 로고    scopus 로고
    • Alzheimer disease: Caspases first
    • J. Avila Alzheimer disease: caspases first Nat Rev Neurol 6 2010 587 588
    • (2010) Nat Rev Neurol , vol.6 , pp. 587-588
    • Avila, J.1
  • 115
    • 79952795522 scopus 로고    scopus 로고
    • Alpha-Synuclein in Parkinson disease and other neurodegenerative disorders
    • M. Eller, and D.R. Williams alpha-Synuclein in Parkinson disease and other neurodegenerative disorders Clin Chem Lab Med 49 2011 403 408
    • (2011) Clin Chem Lab Med , vol.49 , pp. 403-408
    • Eller, M.1    Williams, D.R.2
  • 117
    • 79251484992 scopus 로고    scopus 로고
    • The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism
    • C. Yang, W. Tan, C. Whittle, L. Qiu, L. Cao, and S. Akbarian et al. The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism PLoS One 5 2012 e15878
    • (2012) PLoS One , vol.5 , pp. 15878
    • Yang, C.1    Tan, W.2    Whittle, C.3    Qiu, L.4    Cao, L.5    Akbarian, S.6
  • 118
    • 77956850818 scopus 로고    scopus 로고
    • TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
    • I.R. Mackenzie, R. Rademakers, and M. Neumann TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia Lancet Neurol 9 2010 995 1007
    • (2010) Lancet Neurol , vol.9 , pp. 995-1007
    • MacKenzie, I.R.1    Rademakers, R.2    Neumann, M.3
  • 119
    • 80051785515 scopus 로고    scopus 로고
    • Alexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrease cell viability
    • Y.S. Chen, S.C. Lim, M.H. Chen, R.A. Quinlan, and M.D. Perng Alexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrease cell viability Exp Cell Res 317 2011 2252 2266
    • (2011) Exp Cell Res , vol.317 , pp. 2252-2266
    • Chen, Y.S.1    Lim, S.C.2    Chen, M.H.3    Quinlan, R.A.4    Perng, M.D.5
  • 120
    • 84878078532 scopus 로고    scopus 로고
    • An enzyme-generated fragment of Tau measured in serum shows an inverse correlation to cognitive function
    • In press
    • K. Henriksen, Y. Wang, M.G. Sørensen, N. Barascuk, J. Suhy, and J.T. Pedersen et al. An enzyme-generated fragment of Tau measured in serum shows an inverse correlation to cognitive function PLOS One 2013 In press
    • (2013) PLOS One
    • Henriksen, K.1    Wang, Y.2    Sørensen, M.G.3    Barascuk, N.4    Suhy, J.5    Pedersen, J.T.6
  • 121
    • 33750331979 scopus 로고    scopus 로고
    • Diurnal variation in serum levels of cartilage oligomeric matrix protein in patients with knee osteoarthritis or rheumatoid arthritis
    • DOI 10.1136/ard.2005.051292
    • M.L. Andersson, I.F. Petersson, K.E. Karlsson, E.N. Jonsson, B. Mansson, and D. Heinegard et al. Diurnal variation in serum levels of cartilage oligomeric matrix protein in patients with knee osteoarthritis or rheumatoid arthritis Ann Rheum Dis 65 2006 1490 1494 (Pubitemid 44629128)
    • (2006) Annals of the Rheumatic Diseases , vol.65 , Issue.11 , pp. 1490-1494
    • Andersson, M.L.E.1    Petersson, I.F.2    Karlsson, K.E.3    Jonsson, E.N.4    Mansson, B.5    Heinegard, D.6    Saxne, T.7
  • 122
    • 58149327054 scopus 로고    scopus 로고
    • Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin
    • M.A. Karsdal, I. Byrjalsen, B.J. Riis, and C. Christiansen Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin BMC Clin Pharmacol 8 2008 12
    • (2008) BMC Clin Pharmacol , vol.8 , pp. 12
    • Karsdal, M.A.1    Byrjalsen, I.2    Riis, B.J.3    Christiansen, C.4
  • 123
    • 33746968121 scopus 로고    scopus 로고
    • Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis
    • DOI 10.1002/art.21977
    • S.Y. Kong, T.V. Stabler, L.G. Criscione, A.L. Elliott, J.M. Jordan, and V.B. Kraus Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis Arthritis Rheum 54 2006 2496 2504 (Pubitemid 44205010)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.8 , pp. 2496-2504
    • Kong, S.Y.1    Stabler, T.V.2    Criscione, L.G.3    Elliott, A.L.4    Jordan, J.M.5    Kraus, V.B.6
  • 125
    • 0026531796 scopus 로고
    • Marked diurnal variation in urinary excretion of pyridinium cross-links in premenopausal women
    • A. Schlemmer, C. Hassager, S.B. Jensen, and C. Christiansen Marked diurnal variation in urinary excretion of pyridinium cross-links in premenopausal women J Clin Endocrinol Metab 74 1992 476 480
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 476-480
    • Schlemmer, A.1    Hassager, C.2    Jensen, S.B.3    Christiansen, C.4
  • 126
    • 24644489159 scopus 로고    scopus 로고
    • Variation of serum hyaluronan with activity in individuals with knee osteoarthritis
    • DOI 10.1016/j.joca.2005.05.004, PII S1063458405001354
    • L.G. Criscione, A.L. Elliott, T. Stabler, J.M. Jordan, C.F. Pieper, and V.B. Kraus Variation of serum hyaluronan with activity in individuals with knee osteoarthritis Osteoarthritis Cartilage 13 2005 837 840 (Pubitemid 41263942)
    • (2005) Osteoarthritis and Cartilage , vol.13 , Issue.9 , pp. 837-840
    • Criscione, L.G.1    Elliott, A.L.2    Stabler, T.3    Jordan, J.M.4    Pieper, C.F.5    Kraus, V.B.6
  • 128
    • 0003484310 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration U.S. Food and Drug Administration Rockville, MD
    • U.S. Food and Drug Administration Guidance for industry: bioanalytical method validation 2001 U.S. Food and Drug Administration Rockville, MD
    • (2001) Guidance for Industry: Bioanalytical Method Validation
  • 129
    • 84871434173 scopus 로고    scopus 로고
    • A condensed performance-validation strategy for multiplex detection kits used in studies of human clinical samples
    • C. Belabani, S. Rajasekharan, V. Poupon, T. Johnson, and A. Bar-Or A condensed performance-validation strategy for multiplex detection kits used in studies of human clinical samples J Immunol Methods 387 1-2 2013 1 10
    • (2013) J Immunol Methods , vol.387 , Issue.12 , pp. 1-10
    • Belabani, C.1    Rajasekharan, S.2    Poupon, V.3    Johnson, T.4    Bar-Or, A.5
  • 131
    • 84858433338 scopus 로고    scopus 로고
    • Biomarkers in diabetes: Hemoglobin A1c, vascular and tissue markers
    • T.J. Lyons, and A. Basu Biomarkers in diabetes: hemoglobin A1c, vascular and tissue markers Transl Res 159 2012 303 312
    • (2012) Transl Res , vol.159 , pp. 303-312
    • Lyons, T.J.1    Basu, A.2
  • 132
    • 83255177020 scopus 로고    scopus 로고
    • Inflammatory markers in coronary heart disease
    • M. Madjid, and J.T. Willerson Inflammatory markers in coronary heart disease Br Med Bull 100 2011 23 38
    • (2011) Br Med Bull , vol.100 , pp. 23-38
    • Madjid, M.1    Willerson, J.T.2
  • 133
    • 38349059065 scopus 로고    scopus 로고
    • Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: The Cardiovascular Health Study Cognition Study
    • F. Irie, A.L. Fitzpatrick, O.L. Lopez, L.H. Kuller, R. Peila, and A.B. Newman et al. Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study Cognition Study Arch Neurol 65 2008 89 93
    • (2008) Arch Neurol , vol.65 , pp. 89-93
    • Irie, F.1    Fitzpatrick, A.L.2    Lopez, O.L.3    Kuller, L.H.4    Peila, R.5    Newman, A.B.6
  • 134
    • 80755153025 scopus 로고    scopus 로고
    • TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies
    • T.J. Cohen, V.M. Lee, and J.Q. Trojanowski TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies Trends Mol Med 17 2011 659 667
    • (2011) Trends Mol Med , vol.17 , pp. 659-667
    • Cohen, T.J.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 135
    • 82955198538 scopus 로고    scopus 로고
    • Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS
    • D. Ito, and N. Suzuki Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS Neurology 77 2011 1636 1643
    • (2011) Neurology , vol.77 , pp. 1636-1643
    • Ito, D.1    Suzuki, N.2
  • 136
    • 79953193799 scopus 로고    scopus 로고
    • Plasma apolipoprotein e and Alzheimer disease risk: The AIBL study of aging
    • V.B. Gupta, S.M. Laws, V.L. Villemagne, D. Ames, A.I. Bush, and K.A. Ellis et al. Plasma apolipoprotein E and Alzheimer disease risk: the AIBL study of aging Neurology 76 2011 1091 1098
    • (2011) Neurology , vol.76 , pp. 1091-1098
    • Gupta, V.B.1    Laws, S.M.2    Villemagne, V.L.3    Ames, D.4    Bush, A.I.5    Ellis, K.A.6
  • 138
    • 77954033257 scopus 로고    scopus 로고
    • Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
    • C.C. Rowe, K.A. Ellis, M. Rimajova, P. Bourgeat, K.E. Pike, and G. Jones et al. Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging Neurobiol Aging 31 2010 1275 1283
    • (2010) Neurobiol Aging , vol.31 , pp. 1275-1283
    • Rowe, C.C.1    Ellis, K.A.2    Rimajova, M.3    Bourgeat, P.4    Pike, K.E.5    Jones, G.6
  • 139
    • 84867119124 scopus 로고    scopus 로고
    • Cerebrospinal fluid APOE levels: An endophenotype for genetic studies for Alzheimer's disease
    • C. Cruchaga, J.S. Kauwe, P. Nowotny, K. Bales, E.H. Pickering, and K. Mayo et al. Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease Hum Mol Genet 21 2012 4558 4571
    • (2012) Hum Mol Genet , vol.21 , pp. 4558-4571
    • Cruchaga, C.1    Kauwe, J.S.2    Nowotny, P.3    Bales, K.4    Pickering, E.H.5    Mayo, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.