메뉴 건너뛰기




Volumn 14, Issue 1, 2014, Pages 39-48

The roles of K + channels in cancer

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL;

EID: 84890992887     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc3635     Document Type: Review
Times cited : (382)

References (156)
  • 1
    • 73449119314 scopus 로고    scopus 로고
    • Voltage-gated potassium channels as therapeutic targets
    • Wulff, H., Castle, N. A. & Pardo, L. A. Voltage-gated potassium channels as therapeutic targets. Nature Rev. Drug Discov. 8, 982-1001 (2009).
    • (2009) Nature Rev. Drug Discov , vol.8 , pp. 982-1001
    • Wulff, H.1    Castle, N.A.2    Pardo, L.A.3
  • 2
    • 61349091749 scopus 로고    scopus 로고
    • Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors
    • Downie, B. R. et al. Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors. J. Biol. Chem. 283, 36234-36240 (2008).
    • (2008) J. Biol. Chem , vol.283 , pp. 36234-36240
    • Downie, B.R.1
  • 3
    • 33644551196 scopus 로고    scopus 로고
    • A voltage-driven switch for ion-independent signaling by ether-À-gogo K+ channels
    • Hegle, A. P., Marble, D. D. & Wilson, G. F. A voltage-driven switch for ion-independent signaling by ether-À-gogo K+ channels. Proc. Natl Acad. Sci. USA 103, 2886-2891 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 2886-2891
    • Hegle, A.P.1    Marble, D.D.2    Wilson, G.F.3
  • 4
    • 29844437655 scopus 로고    scopus 로고
    • International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
    • Gutman, G. A. et al. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol. Rev. 57, 473-508 (2005).
    • (2005) Pharmacol. Rev , vol.57 , pp. 473-508
    • Gutman, G.A.1
  • 5
    • 33748943301 scopus 로고    scopus 로고
    • Non-conducting functions of voltage-gated ion channels
    • Kaczmarek, L. K. Non-conducting functions of voltage-gated ion channels. Nature Rev. Neurosci. 7, 761-771 (2006).
    • (2006) Nature Rev. Neurosci , vol.7 , pp. 761-771
    • Kaczmarek, L.K.1
  • 6
    • 84875255913 scopus 로고    scopus 로고
    • Oncochannels
    • Huber, S. M. Oncochannels. Cell Calcium 53, 241-255 (2013).
    • (2013) Cell Calcium , vol.53 , pp. 241-255
    • Huber, S.M.1
  • 7
    • 79951506090 scopus 로고    scopus 로고
    • K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension
    • Choi, M. et al. K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension. Science 331, 768-772 (2011).
    • (2011) Science , vol.331 , pp. 768-772
    • Choi, M.1
  • 8
    • 0035895887 scopus 로고    scopus 로고
    • Herg k+ channels activation during β1 integrin-mediated adhesion to fibronectin induces an upregulation of αvβ3 integrin in the preosteoclastic leukemia cell line flg 29.1
    • Hofmann, G. et al. HERG K+ channels activation during β1 integrin-mediated adhesion to fibronectin induces an upregulation of αvβ3 integrin in the preosteoclastic leukemia cell line FLG 29.1. J. Biol. Chem. 276, 4923-4931 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 4923-4931
    • Hofmann, G.1
  • 9
    • 84865049417 scopus 로고    scopus 로고
    • Stimulation of HERG channel activity by β-catenin
    • Munoz, C. et al. Stimulation of HERG channel activity by β-catenin. PLoS ONE 7, e43353 (2012).
    • (2012) PLoS ONE , vol.7
    • Munoz, C.1
  • 10
    • 84877946756 scopus 로고    scopus 로고
    • P38 MAPK regulates the expression of ether a gogo potassium channel in human osteosarcoma cells
    • Wu, X. et al. p38 MAPK regulates the expression of ether a gogo potassium channel in human osteosarcoma cells. Radiol Oncol. 47, 42-49 (2013).
    • (2013) Radiol Oncol , vol.47 , pp. 42-49
    • Wu, X.1
  • 11
    • 79961015640 scopus 로고    scopus 로고
    • The two-pore domain potassium channel KCNK5: Induction by estrogen receptor α and role in proliferation of breast cancer cells
    • Alvarez-Baron, C. P., Jonsson, P., Thomas, C., Dryer, S. E. & Williams, C. The two-pore domain potassium channel KCNK5: induction by estrogen receptor α and role in proliferation of breast cancer cells. Mol. Endocrinol. 25, 1326-1336 (2011).
    • (2011) Mol. Endocrinol , vol.25 , pp. 1326-1336
    • Alvarez-Baron, C.P.1    Jonsson, P.2    Thomas, C.3    Dryer, S.E.4    Williams, C.5
  • 12
    • 33745828097 scopus 로고    scopus 로고
    • Genetic and expression analysis of the KCNRG gene in hepatocellular carcinomas
    • Cho, Y. G. et al. Genetic and expression analysis of the KCNRG gene in hepatocellular carcinomas. Exp. Mol. Med. 38, 247-255 (2006).
    • (2006) Exp. Mol. Med , vol.38 , pp. 247-255
    • Cho, Y.G.1
  • 13
    • 0037468613 scopus 로고    scopus 로고
    • A new human gene KCNRG encoding potassium channel regulating protein is a cancer suppressor gene candidate located in 13q14.3
    • Ivanov, D. V. et al. A new human gene KCNRG encoding potassium channel regulating protein is a cancer suppressor gene candidate located in 13q14.3. FEBS Lett. 539, 156-160 (2003).
    • (2003) FEBS Lett , vol.539 , pp. 156-160
    • Ivanov, D.V.1
  • 14
    • 73949132375 scopus 로고    scopus 로고
    • Potassium channel regulator KCNRG regulates surface expression of Shaker-type potassium channels
    • Usman, H. & Mathew, M. K. Potassium channel regulator KCNRG regulates surface expression of Shaker-type potassium channels. Biochem. Biophys. Res. Commun. 391, 1301-1305 (2010).
    • (2010) Biochem. Biophys. Res. Commun , vol.391 , pp. 1301-1305
    • Usman, H.1    Mathew, M.K.2
  • 15
    • 68949088285 scopus 로고    scopus 로고
    • Deregulation of 2 potassium channels in pancreas adenocarcinomas: Implication of KV1.3 gene promoter methylation
    • Brevet, M. et al. Deregulation of 2 potassium channels in pancreas adenocarcinomas: implication of KV1.3 gene promoter methylation. Pancreas 38, 649-654 (2009).
    • (2009) Pancreas , vol.38 , pp. 649-654
    • Brevet, M.1
  • 16
    • 67650444360 scopus 로고    scopus 로고
    • DNA methylation of KV1.3 potassium channel gene promoter is associated with poorly differentiated breast adenocarcinoma
    • Brevet, M., Haren, N., Sevestre, H., Merviel, P. & Ouadid-Ahidouch, H. DNA methylation of KV1.3 potassium channel gene promoter is associated with poorly differentiated breast adenocarcinoma. Cell Physiol. Biochem. 24, 25-32 (2009).
    • (2009) Cell Physiol. Biochem , vol.24 , pp. 25-32
    • Brevet, M.1    Haren, N.2    Sevestre, H.3    Merviel, P.4    Ouadid-Ahidouch, H.5
  • 17
    • 41549108332 scopus 로고    scopus 로고
    • DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients
    • Feng, Q. et al. DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients. Cancer Epidemiol. Biomarkers Prev. 17, 645-654 (2008).
    • (2008) Cancer Epidemiol. Biomarkers Prev , vol.17 , pp. 645-654
    • Feng, Q.1
  • 18
    • 84879580092 scopus 로고    scopus 로고
    • Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K+ channel
    • Cicek, M. S. et al. Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K+ channel. Hum. Mol. Genet. 22, 3038-3047 (2013).
    • (2013) Hum. Mol. Genet , vol.22 , pp. 3038-3047
    • Cicek, M.S.1
  • 19
    • 84867334589 scopus 로고    scopus 로고
    • Frequent aberrant expression of the human ether à gogo (hEAG1) potassium channel in head and neck cancer: Pathobiological mechanisms and clinical implications
    • Menendez, S. T. et al. Frequent aberrant expression of the human ether à gogo (hEAG1) potassium channel in head and neck cancer: pathobiological mechanisms and clinical implications. J. Mol. Med. 90, 1173-1184 (2012).
    • (2012) J. Mol. Med , vol.90 , pp. 1173-1184
    • Menendez, S.T.1
  • 20
    • 18844467600 scopus 로고    scopus 로고
    • Herg encodes a K+ current highly conserved in tumors of different histogenesis: A selective advantage for cancer cells?
    • Bianchi, L. et al. herg encodes a K+ current highly conserved in tumors of different histogenesis: A selective advantage for cancer cells? Cancer Res. 58, 815-822 (1998).
    • (1998) Cancer Res , vol.58 , pp. 815-822
    • Bianchi, L.1
  • 21
    • 25844523898 scopus 로고    scopus 로고
    • Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation
    • Cheong, A. et al. Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation. Mol. Cell 20, 45-52 (2005).
    • (2005) Mol. Cell , vol.20 , pp. 45-52
    • Cheong, A.1
  • 22
    • 79957914650 scopus 로고    scopus 로고
    • Transcriptional and post-transcriptional mechanisms for oncogenic overexpression of ether à gogo K+ channel
    • Lin, H. et al. Transcriptional and post-transcriptional mechanisms for oncogenic overexpression of ether à gogo K+ channel. PLoS ONE 6, e20362 (2011).
    • (2011) PLoS ONE , vol.6
    • Lin, H.1
  • 23
    • 65949083785 scopus 로고    scopus 로고
    • Estrogens and human papilloma virus oncogenes regulate human etheragogo1 potassium channel expression
    • Diaz, L. et al. Estrogens and human papilloma virus oncogenes regulate human etheragogo1 potassium channel expression. Cancer Res. 69, 3300-3307 (2009).
    • (2009) Cancer Res , vol.69 , pp. 3300-3307
    • Diaz, L.1
  • 24
    • 34548648008 scopus 로고    scopus 로고
    • Diazoxide preconditioning alleviates apoptosis of hippocampal neurons induced by anoxia-reoxygenation in vitro through upregulation of Bcl2/ Bax protein ratio
    • Liu, R. G., Wang, W. J., Song, N., Chen, Y. Q. & Li, L. H. Diazoxide preconditioning alleviates apoptosis of hippocampal neurons induced by anoxia-reoxygenation in vitro through upregulation of Bcl2/ Bax protein ratio. Sheng Li Xue Bao 58, 345-350 (2006).
    • (2006) Sheng Li Xue Bao , vol.58 , pp. 345-350
    • Liu, R.G.1    Wang, W.J.2    Song, N.3    Chen, Y.Q.4    Li, L.H.5
  • 25
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus type16 and type18 promotes the degradation of p53
    • Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J. & Howley, P. M. The E6 oncoprotein encoded by human papillomavirus type16 and type18 promotes the degradation of p53. Cell 63, 1129-1136 (1990).
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 26
    • 0037169559 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E7 binds to E2F1 and activates E2F1driven transcription in a retinoblastoma protein-independent manner
    • Hwang, S. G., Lee, D. Y., Kim, J. Y., Seo, T. G. & Choe, J. H. Human papillomavirus type 16 E7 binds to E2F1 and activates E2F1driven transcription in a retinoblastoma protein-independent manner. J. Biol. Chem. 277, 2923-2930 (2002).
    • (2002) J. Biol. Chem , vol.277 , pp. 2923-2930
    • Hwang, S.G.1    Lee, D.Y.2    Kim, J.Y.3    Seo, T.G.4    Choe, J.H.5
  • 27
    • 34547955937 scopus 로고    scopus 로고
    • IGF1 activates hEAG K+ channels through an Akt-dependent signaling pathway in breast cancer cells: Role in cell proliferation
    • Borowiec, A. S. et al. IGF1 activates hEAG K+ channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation. J. Cell. Physiol. 212, 690-701 (2007).
    • (2007) J. Cell. Physiol , vol.212 , pp. 690-701
    • Borowiec, A.S.1
  • 28
    • 0033588217 scopus 로고    scopus 로고
    • Phosphoinositide 3oh kinase (pi3k) and pkb/akt delay the onset of p53mediated, transcriptionally dependent apoptosis
    • Sabbatini, P. & McCormick, F. Phosphoinositide 3OH kinase (PI3K) and PKB/Akt delay the onset of p53mediated, transcriptionally dependent apoptosis. J. Biol. Chem. 274, 24263-24269 (1999).
    • (1999) J. Biol. Chem , vol.274 , pp. 24263-24269
    • Sabbatini, P.1    McCormick, F.2
  • 29
    • 84872681759 scopus 로고    scopus 로고
    • MiR2963p regulates cell growth and multi-drug resistance of human glioblastoma by targeting etheragogo (EAG1
    • Bai, Y. et al. MiR2963p regulates cell growth and multi-drug resistance of human glioblastoma by targeting etheragogo (EAG1). Eur. J. Cancer 49, 710-724 (2013).
    • (2013) Eur. J. Cancer , vol.49 , pp. 710-724
    • Bai, Y.1
  • 30
    • 80054082076 scopus 로고    scopus 로고
    • MicroRNA296 is enriched in cancer cells and downregulates p21WAF1 mRNA expression via interaction with its 3Ŷ untranslated region
    • Yoon, A.R. et al. MicroRNA296 is enriched in cancer cells and downregulates p21WAF1 mRNA expression via interaction with its 3Ŷ untranslated region. Nucleic Acids Res. 39, 8078-8091 (2011).
    • (2011) Nucleic Acids Res , vol.39 , pp. 8078-8091
    • Yoon, A.R.1
  • 31
    • 33847389726 scopus 로고    scopus 로고
    • Expression of voltage-gated potassium channels in human and mouse colonic carcinoma
    • Ousingsawat, J. et al. Expression of voltage-gated potassium channels in human and mouse colonic carcinoma. Clin. Cancer Res. 13, 824-831 (2007).
    • (2007) Clin. Cancer Res , vol.13 , pp. 824-831
    • Ousingsawat, J.1
  • 32
    • 0033570146 scopus 로고    scopus 로고
    • Oncogenic potential of EAG K+ channels
    • Pardo, L. A. et al. Oncogenic potential of EAG K+ channels. EMBO J. 18, 5540-5547 (1999).
    • (1999) EMBO J , vol.18 , pp. 5540-5547
    • Pardo, L.A.1
  • 33
    • 84877905311 scopus 로고    scopus 로고
    • Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice
    • Ufartes, R. et al. Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice. Hum. Mol. Genet. 22, 2247-2262 (2013).
    • (2013) Hum. Mol. Genet , vol.22 , pp. 2247-2262
    • Ufartes, R.1
  • 34
    • 49249108871 scopus 로고    scopus 로고
    • Eag1 potassium channel immunohistochemistry in the CNS of adult rat and selected regions of human brain
    • Martin, S. et al. Eag1 potassium channel immunohistochemistry in the CNS of adult rat and selected regions of human brain. Neuroscience 155, 833-844 (2008).
    • (2008) Neuroscience , vol.155 , pp. 833-844
    • Martin, S.1
  • 35
    • 33750390132 scopus 로고    scopus 로고
    • Overexpression of Eag1 potassium channels in clinical tumours
    • Hemmerlein, B. et al. Overexpression of Eag1 potassium channels in clinical tumours. Mol. Cancer 5, 41 (2006).
    • (2006) Mol. Cancer , vol.5 , pp. 41
    • Hemmerlein, B.1
  • 36
    • 33750419308 scopus 로고    scopus 로고
    • Ether a gogo potassium channel expression in soft tissue sarcoma patients
    • de Queiroz, F. M., Suarez-Kurtz, G., Stühmer, W. & Pardo, L. A. Ether a gogo potassium channel expression in soft tissue sarcoma patients. Mol. Cancer 5, 42 (2006).
    • (2006) Mol. Cancer , vol.5 , pp. 42
    • De Queiroz, F.M.1    Suarez-Kurtz, G.2    Stühmer, W.3    Pardo, L.A.4
  • 37
    • 77949541790 scopus 로고    scopus 로고
    • The potassium channel Ether à gogo is a novel prognostic factor with functional relevance in acute myeloid leukemia
    • Agarwal, J. R., Griesinger, F., Stühmer, W. & Pardo, L. A. The potassium channel Ether à gogo is a novel prognostic factor with functional relevance in acute myeloid leukemia. Mol. Cancer 9, 18 (2010).
    • (2010) Mol. Cancer , vol.9 , pp. 18
    • Agarwal, J.R.1    Griesinger, F.2    Stühmer, W.3    Pardo, L.A.4
  • 38
    • 78649741809 scopus 로고    scopus 로고
    • The Eag potassium channel as a new prognostic marker in ovarian cancer
    • Asher, V. et al. The Eag potassium channel as a new prognostic marker in ovarian cancer. Diagn. Pathol. 5, 78 (2010).
    • (2010) Diagn. Pathol , vol.5 , pp. 78
    • Asher, V.1
  • 39
    • 36048960918 scopus 로고    scopus 로고
    • Aberrant expression of Eag1 potassium channels in gastric cancer patients and cell lines
    • Ding, X. W., Luo, H. S., Jin, X., Yan, J. J. & Ai, Y. W. Aberrant expression of Eag1 potassium channels in gastric cancer patients and cell lines. Med. Oncol. 24, 345-350 (2007).
    • (2007) Med. Oncol , vol.24 , pp. 345-350
    • Ding, X.W.1    Luo, H.S.2    Jin, X.3    Yan, J.J.4    Ai, Y.W.5
  • 40
    • 34247135947 scopus 로고    scopus 로고
    • Aberrant expression of ether a gogo potassium channel in colorectal cancer patients and cell lines
    • Ding, X. W., Yan, J. J., An, P., Lu, P. & Luo, H. S. Aberrant expression of ether a gogo potassium channel in colorectal cancer patients and cell lines. World J. Gastroenterol. 13, 1257-1261 (2007).
    • (2007) World J. Gastroenterol , vol.13 , pp. 1257-1261
    • Ding, X.W.1    Yan, J.J.2    An, P.3    Lu, P.4    Luo, H.S.5
  • 41
    • 67349234461 scopus 로고    scopus 로고
    • Differential expression of potassium ion channels in human renal cell carcinoma
    • Wadhwa, S., Wadhwa, P., Dinda, A. K. & Gupta, N. P. Differential expression of potassium ion channels in human renal cell carcinoma. Int. Urol. Nephrol. 41, 251-257 (2009).
    • (2009) Int. Urol. Nephrol , vol.41 , pp. 251-257
    • Wadhwa, S.1    Wadhwa, P.2    Dinda, A.K.3    Gupta, N.P.4
  • 42
    • 34547636154 scopus 로고    scopus 로고
    • Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity
    • Gómez-Varela, D. et al. Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity. Cancer Res. 67, 7343-7349 (2007).
    • (2007) Cancer Res , vol.67 , pp. 7343-7349
    • Gómez-Varela, D.1
  • 43
    • 80052559599 scopus 로고    scopus 로고
    • Tumor cell-selective apoptosis induction through targeting of KV10.1 via bifunctional TRAIL antibody
    • Hartung, F., Stühmer, W. & Pardo, L. A. Tumor cell-selective apoptosis induction through targeting of KV10.1 via bifunctional TRAIL antibody. Mol. Cancer 10, 109 (2011).
    • (2011) Mol. Cancer , vol.10 , pp. 109
    • Hartung, F.1    Stühmer, W.2    Pardo, L.A.3
  • 44
    • 77954676151 scopus 로고    scopus 로고
    • Integrins and ion channels in cell migration: Implications for neuronal development, wound healing and metastatic spread
    • Becchetti, A. & Arcangeli, A. Integrins and ion channels in cell migration: implications for neuronal development, wound healing and metastatic spread. Adv. Exp. Med. Biol. 674, 107-123 (2010).
    • (2010) Adv. Exp. Med. Biol , vol.674 , pp. 107-123
    • Becchetti, A.1    Arcangeli, A.2
  • 45
    • 84867717110 scopus 로고    scopus 로고
    • Role of ion channels and transporters in cell migration
    • Schwab, A., Fabian, A., Hanley, P. J. & Stock, C. Role of ion channels and transporters in cell migration. Physiol. Rev. 92, 1865-1913 (2012).
    • (2012) Physiol. Rev , vol.92 , pp. 1865-1913
    • Schwab, A.1    Fabian, A.2    Hanley, P.J.3    Stock, C.4
  • 46
    • 10744230928 scopus 로고    scopus 로고
    • Focal adhesion kinase pp125FAK interacts with the large conductance calcium-activated hSlo potassium channel in human osteoblasts: Potential role in mechanotransduction
    • Rezzonico, R. et al. Focal adhesion kinase pp125FAK interacts with the large conductance calcium-activated hSlo potassium channel in human osteoblasts: potential role in mechanotransduction. J. Bone Miner. Res. 18, 1863-1871 (2003).
    • (2003) J. Bone Miner. Res , vol.18 , pp. 1863-1871
    • Rezzonico, R.1
  • 47
    • 51449098575 scopus 로고    scopus 로고
    • Formation of Kv2.1FAK complex as a mechanism of FAK activation, cell polarization and enhanced motility
    • Wei, J. F. et al. Formation of Kv2.1FAK complex as a mechanism of FAK activation, cell polarization and enhanced motility. J. Cell. Physiol. 217, 544-557 (2008).
    • (2008) J. Cell. Physiol , vol.217 , pp. 544-557
    • Wei, J.F.1
  • 48
    • 79958007658 scopus 로고    scopus 로고
    • Cortactin is required for Ncadherin regulation of Kv1.5 channel function
    • Cheng, L., Yung, A., Covarrubias, M. & Radice, G. L. Cortactin is required for Ncadherin regulation of Kv1.5 channel function. J. Biol. Chem. 286, 20478-20489 (2011).
    • (2011) J. Biol. Chem , vol.286 , pp. 20478-20489
    • Cheng, L.1    Yung, A.2    Covarrubias, M.3    Radice, G.L.4
  • 49
    • 0037064067 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Kv1.2 modulates its interaction with the actin-binding protein cortactin
    • Hattan, D., Nesti, E., Cachero, T. G. & Morielli, A. D. Tyrosine phosphorylation of Kv1.2 modulates its interaction with the actin-binding protein cortactin. J. Biol. Chem. 277, 38596-38606 (2002).
    • (2002) J. Biol. Chem , vol.277 , pp. 38596-38606
    • Hattan, D.1    Nesti, E.2    Cachero, T.G.3    Morielli, A.D.4
  • 50
    • 84866714848 scopus 로고    scopus 로고
    • The TASK1 channel inhibitor A293 shows efficacy in a mouse model of multiple sclerosis
    • Bittner, S. et al. The TASK1 channel inhibitor A293 shows efficacy in a mouse model of multiple sclerosis. Exp. Neurol. 238, 149-155 (2012).
    • (2012) Exp. Neurol , vol.238 , pp. 149-155
    • Bittner, S.1
  • 51
    • 33845623249 scopus 로고    scopus 로고
    • A noncanonical SH3 domain binding motif links BK channels to the actin cytoskeleton via the SH3 adapter cortactin
    • Tian, L. et al. A noncanonical SH3 domain binding motif links BK channels to the actin cytoskeleton via the SH3 adapter cortactin. FASEB J. 20, 2588-2590 (2006).
    • (2006) FASEB J , vol.20 , pp. 2588-2590
    • Tian, L.1
  • 52
    • 36849089976 scopus 로고    scopus 로고
    • An essential role for cortactin in the modulation of the potassium channel Kv1.2
    • Williams, M. R., Markey, J. C., Doczi, M. A. & Morielli, A. D. An essential role for cortactin in the modulation of the potassium channel Kv1.2. Proc. Natl Acad. Sci. USA 104, 17412-17417 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 17412-17417
    • Williams, M.R.1    Markey, J.C.2    Doczi, M.A.3    Morielli, A.D.4
  • 53
    • 0034600069 scopus 로고    scopus 로고
    • Extracellular K+ and opening of voltage-gated potassium channels activate T cell integrin function: Physical and functional association between Kv1.3 channels and β1 integrins
    • Levite, M. et al. Extracellular K+ and opening of voltage-gated potassium channels activate T cell integrin function: Physical and functional association between Kv1.3 channels and β1 integrins. J. Exp. Med. 191, 1167-1176 (2000).
    • (2000) J. Exp. Med , vol.191 , pp. 1167-1176
    • Levite, M.1
  • 54
    • 21144435502 scopus 로고    scopus 로고
    • Human etheragogorelated gene 1 channels are physically linked to β1 integrins and modulate adhesion-dependent signaling
    • Cherubini, A. et al. Human etheragogorelated gene 1 channels are physically linked to β1 integrins and modulate adhesion-dependent signaling. Mol. Biol. Cell 16, 2972-2983 (2005).
    • (2005) Mol. Biol. Cell , vol.16 , pp. 2972-2983
    • Cherubini, A.1
  • 55
    • 34548036519 scopus 로고    scopus 로고
    • VEGFR1 (FLT1), β1 integrin, and hERG K+ channel for a macromolecular signaling complex in acute myeloid leukemia: Role in cell migration and clinical outcome
    • Pillozzi, S. et al. VEGFR1 (FLT1), β1 integrin, and hERG K+ channel for a macromolecular signaling complex in acute myeloid leukemia: role in cell migration and clinical outcome. Blood 110, 1238-1250 (2007).
    • (2007) Blood , vol.110 , pp. 1238-1250
    • Pillozzi, S.1
  • 56
    • 77954664903 scopus 로고    scopus 로고
    • Physical and functional interaction between integrins and hERG1 channels in cancer cells
    • Pillozzi, S. & Arcangeli, A. Physical and functional interaction between integrins and hERG1 channels in cancer cells. Adv. Exp. Med. Biol. 674, 55-67 (2010).
    • (2010) Adv. Exp. Med. Biol , vol.674 , pp. 55-67
    • Pillozzi, S.1    Arcangeli, A.2
  • 57
    • 67349213575 scopus 로고    scopus 로고
    • The role of hERG1 K+ channels and a functional link between hERG1 K+ channels and SDF1 in acute leukemic cell migration
    • Li, H. et al. The role of hERG1 K+ channels and a functional link between hERG1 K+ channels and SDF1 in acute leukemic cell migration. Exp. Cell Res. 315, 2256-2264 (2009).
    • (2009) Exp. Cell Res , vol.315 , pp. 2256-2264
    • Li, H.1
  • 58
    • 70350001105 scopus 로고    scopus 로고
    • Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDAMB435S melanoma cell proliferation and migration
    • Afrasiabi, E. et al. Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDAMB435S melanoma cell proliferation and migration. Cell Signal 22, 57-64 (2010).
    • (2010) Cell Signal , vol.22 , pp. 57-64
    • Afrasiabi, E.1
  • 59
    • 84867427541 scopus 로고    scopus 로고
    • Sphingosine 1phosphate and human ether-À-gogorelated gene potassium channels modulate migration in human anaplastic thyroid cancer cells
    • Asghar, M. Y., Viitanen, T., Kemppainen, K. & Tornquist, K. Sphingosine 1phosphate and human ether-À-gogorelated gene potassium channels modulate migration in human anaplastic thyroid cancer cells. Endocr. Relat. Cancer 19, 667-680 (2012).
    • (2012) Endocr. Relat. Cancer , vol.19 , pp. 667-680
    • Asghar, M.Y.1    Viitanen, T.2    Kemppainen, K.3    Tornquist, K.4
  • 60
    • 0029619246 scopus 로고
    • A novel inward-rectifying K+ current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells
    • Arcangeli, A. et al. A novel inward-rectifying K+ current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells. J. Physiol. 489, 455-471 (1995).
    • (1995) J. Physiol , vol.489 , pp. 455-471
    • Arcangeli, A.1
  • 61
    • 0031428009 scopus 로고    scopus 로고
    • HERG- and IRK-like inward rectifier currents are sequentially expressed during neuronal development of neural crest cells and their derivatives
    • Arcangeli, A. et al. HERG- and IRK-like inward rectifier currents are sequentially expressed during neuronal development of neural crest cells and their derivatives. Eur. J. Neurosci. 9, 2596-2604 (1997).
    • (1997) Eur. J. Neurosci , vol.9 , pp. 2596-2604
    • Arcangeli, A.1
  • 62
    • 0036738165 scopus 로고    scopus 로고
    • HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors
    • Pillozzi, S. et al. HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors. Leukemia 16, 1791-1798 (2002).
    • (2002) Leukemia , vol.16 , pp. 1791-1798
    • Pillozzi, S.1
  • 63
    • 0037166235 scopus 로고    scopus 로고
    • Functional upregulation of HERG K+ channels in neoplastic hematopoietic cells
    • Smith, G. A. M. et al. Functional upregulation of HERG K+ channels in neoplastic hematopoietic cells. J. Biol. Chem. 277, 18528-18534 (2002).
    • (2002) J. Biol. Chem , vol.277 , pp. 18528-18534
    • Smith, G.A.M.1
  • 64
    • 9144274941 scopus 로고    scopus 로고
    • Herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells
    • Lastraioli, E. et al. herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells. Cancer Res. 64, 606-611 (2004).
    • (2004) Cancer Res , vol.64 , pp. 606-611
    • Lastraioli, E.1
  • 65
    • 42549114399 scopus 로고    scopus 로고
    • Expression and significance of HERG protein in gastric cancer
    • Shao, X. D. et al. Expression and significance of HERG protein in gastric cancer. Cancer Biol. Ther. 7, 45-50 (2008).
    • (2008) Cancer Biol. Ther , vol.7 , pp. 45-50
    • Shao, X.D.1
  • 66
    • 77950364723 scopus 로고    scopus 로고
    • Prognostic significance of hERG1 expression in gastric cancer
    • Ding, X. W. et al. Prognostic significance of hERG1 expression in gastric cancer. Dig. Dis. Sci. 55, 1004-1010 (2010).
    • (2010) Dig. Dis. Sci , vol.55 , pp. 1004-1010
    • Ding, X.W.1
  • 67
    • 73249122449 scopus 로고    scopus 로고
    • HERG1 gene expression as a specific tumor marker in colorectal tissues
    • Dolderer, J. H. et al. HERG1 gene expression as a specific tumor marker in colorectal tissues. Ejso 36, 72-77 (2010).
    • (2010) Ejso , vol.36 , pp. 72-77
    • Dolderer, J.H.1
  • 68
    • 84856759618 scopus 로고    scopus 로고
    • Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells
    • Glassmeier, G. et al. Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells. Pflugers Arch. 463, 365-376 (2012).
    • (2012) Pflugers Arch , vol.463 , pp. 365-376
    • Glassmeier, G.1
  • 69
    • 84864561940 scopus 로고    scopus 로고
    • Role of HERG1 potassium channel in both malignant transformation and disease progression in head and neck carcinomas
    • Menendez, S. T. et al. Role of HERG1 potassium channel in both malignant transformation and disease progression in head and neck carcinomas. Mod. Pathol. 25, 1069-1078 (2012).
    • (2012) Mod. Pathol , vol.25 , pp. 1069-1078
    • Menendez, S.T.1
  • 70
    • 33749252189 scopus 로고    scopus 로고
    • Herg1 channels in human esophagus: Evidence for their aberrant expression in the malignant progression of Barrett's esophagus
    • Lastraioli, E. et al. hERG1 channels in human esophagus: evidence for their aberrant expression in the malignant progression of Barrett's esophagus. J. Cell. Physiol. 209, 398-404 (2006).
    • (2006) J. Cell. Physiol , vol.209 , pp. 398-404
    • Lastraioli, E.1
  • 71
    • 27144531556 scopus 로고    scopus 로고
    • HERG1 channels are overexpressed in glioblastoma multiforme and modulate VEGF secretion in glioblastoma cell lines
    • Masi, A. et al. hERG1 channels are overexpressed in glioblastoma multiforme and modulate VEGF secretion in glioblastoma cell lines. Br. J. Cancer 93, 781-792 (2005).
    • (2005) Br. J. Cancer , vol.93 , pp. 781-792
    • Masi, A.1
  • 72
    • 0037474225 scopus 로고    scopus 로고
    • Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells
    • Crociani, O. et al. Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells. J. Biol. Chem. 278, 2947-2955 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 2947-2955
    • Crociani, O.1
  • 73
    • 25144490098 scopus 로고    scopus 로고
    • The potent inhibitory effects of cisapride, a specific blocker for human etheragogorelated gene (HERG) channel, on gastric cancer cells
    • Shao, X. D. et al. The potent inhibitory effects of cisapride, a specific blocker for human etheragogorelated gene (HERG) channel, on gastric cancer cells. Cancer Biol. Ther. 4, 295-301 (2005).
    • (2005) Cancer Biol. Ther , vol.4 , pp. 295-301
    • Shao, X.D.1
  • 74
    • 37549072709 scopus 로고    scopus 로고
    • Silencing of herg gene by shRNA inhibits SHSY5Y cell growth in vitro and in vivo
    • Zhao, J., Wei, X. L., Jia, Y. S. & Zheng, J. Q. Silencing of herg gene by shRNA inhibits SHSY5Y cell growth in vitro and in vivo. Eur. J. Pharmacol. 579, 50-57 (2008).
    • (2008) Eur. J. Pharmacol , vol.579 , pp. 50-57
    • Zhao, J.1    Wei, X.L.2    Jia, Y.S.3    Zheng, J.Q.4
  • 75
    • 84866679694 scopus 로고    scopus 로고
    • HERG K+ channels: Structure, function, and clinical significance
    • Vandenberg, J. I. et al. hERG K+ channels: structure, function, and clinical significance. Physiol. Rev. 92, 1393-1478 (2012).
    • (2012) Physiol. Rev , vol.92 , pp. 1393-1478
    • Vandenberg, J.I.1
  • 76
    • 49449109702 scopus 로고    scopus 로고
    • Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells
    • Guasti, L. et al. Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells. Mol. Cell. Biol. 28, 5043-5060 (2008).
    • (2008) Mol. Cell. Biol , vol.28 , pp. 5043-5060
    • Guasti, L.1
  • 77
  • 78
    • 0028176889 scopus 로고
    • Oscillating activity of a Ca2+-sensitive K+ channel. A prerequisite for migration of transformed Madin-Darby canine kidney focus cells
    • Schwab, A., Wojnowski, L., Gabriel, K. & Oberleithner, H. Oscillating activity of a Ca2+-sensitive K+ channel. A prerequisite for migration of transformed Madin-Darby canine kidney focus cells. J. Clin. Invest. 93, 1631-1636 (1994).
    • (1994) J. Clin. Invest , vol.93 , pp. 1631-1636
    • Schwab, A.1    Wojnowski, L.2    Gabriel, K.3    Oberleithner, H.4
  • 79
    • 0032574729 scopus 로고    scopus 로고
    • Migrating transformed mdck cells are able to structurally polarize a voltage-activated K+ channel
    • Reinhardt, J., Golenhofen, N., Pongs, O., Oberleithner, H. & Schwab, A. Migrating transformed mdck cells are able to structurally polarize a voltage-activated K+ channel. Proc. Natl Acad. Sci. USA 95, 5378-5382 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 5378-5382
    • Reinhardt, J.1    Golenhofen, N.2    Pongs, O.3    Oberleithner, H.4    Schwab, A.5
  • 81
    • 0032788491 scopus 로고    scopus 로고
    • Migration of transformed renal epithelial cells is regulated by K+ channel modulation of actin cytoskeleton and cell volume
    • Schwab, A., Schuricht, B., Seeger, P., Reinhardt, J. & Dartsch, P. C. Migration of transformed renal epithelial cells is regulated by K+ channel modulation of actin cytoskeleton and cell volume. Pflugers Arch. 438, 330-337 (1999).
    • (1999) Pflugers Arch , vol.438 , pp. 330-337
    • Schwab, A.1    Schuricht, B.2    Seeger, P.3    Reinhardt, J.4    Dartsch, P.C.5
  • 82
    • 0036209260 scopus 로고    scopus 로고
    • Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release
    • Liu, D., Lu, C., Wan, R., Auyeung, W. W. & Mattson, M. P. Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release. J. Cereb. Blood Flow Metab. 22, 431-443 (2002).
    • (2002) J. Cereb. Blood Flow Metab , vol.22 , pp. 431-443
    • Liu, D.1    Lu, C.2    Wan, R.3    Auyeung, W.W.4    Mattson, M.P.5
  • 83
    • 0036599238 scopus 로고    scopus 로고
    • BK channels in human glioma cells have enhanced calcium sensitivity
    • Ransom, C. B., Liu, X. & Sontheimer, H. BK channels in human glioma cells have enhanced calcium sensitivity. Glia 38, 281-291 (2002).
    • (2002) Glia , vol.38 , pp. 281-291
    • Ransom, C.B.1    Liu, X.2    Sontheimer, H.3
  • 84
    • 4744356175 scopus 로고    scopus 로고
    • Role for calcium-activated potassium channels (BK) in growth control of human malignant glioma cells
    • Weaver, A. K., Liu, X. & Sontheimer, H. Role for calcium-activated potassium channels (BK) in growth control of human malignant glioma cells. J. Neurosci. Res. 78, 224-234 (2004).
    • (2004) J. Neurosci. Res , vol.78 , pp. 224-234
    • Weaver, A.K.1    Liu, X.2    Sontheimer, H.3
  • 85
    • 77953794483 scopus 로고    scopus 로고
    • Cxcl12induced glioblastoma cell migration requires intermediate conductance ca2+-activated k+ channel activity
    • Sciaccaluga, M. et al. CXCL12induced glioblastoma cell migration requires intermediate conductance Ca2+-activated K+ channel activity. Am. J. Physiol. Cell Physiol. 299, C175-C184 (2010).
    • (2010) Am. J. Physiol. Cell Physiol , vol.299
    • Sciaccaluga, M.1
  • 86
    • 84867732950 scopus 로고    scopus 로고
    • Expression and role of the intermediate-conductance calcium-activated potassium channel KCa3.1 in glioblastoma
    • Catacuzzeno, L., Fioretti, B. & Franciolini, F. Expression and role of the intermediate-conductance calcium-activated potassium channel KCa3.1 in glioblastoma. J. Signal Trans. 2012, 421564 (2012).
    • (2012) J. Signal Trans , vol.2012 , pp. 421564
    • Catacuzzeno, L.1    Fioretti, B.2    Franciolini, F.3
  • 87
    • 84867706193 scopus 로고    scopus 로고
    • The inhibition of KCa3.1 channels activity reduces cell motility in glioblastoma derived cancer stem cells
    • Ruggieri, P. et al. The inhibition of KCa3.1 channels activity reduces cell motility in glioblastoma derived cancer stem cells. PLoS ONE 7, e47825 (2012).
    • (2012) PLoS ONE , vol.7
    • Ruggieri, P.1
  • 88
    • 80655127838 scopus 로고    scopus 로고
    • Ionizing radiation induces migration of glioblastoma cells by activating BK K+ channels
    • Steinle, M. et al. Ionizing radiation induces migration of glioblastoma cells by activating BK K+ channels. Radiother. Oncol. 101, 122-126 (2011).
    • (2011) Radiother. Oncol , vol.101 , pp. 122-126
    • Steinle, M.1
  • 89
    • 77953683624 scopus 로고    scopus 로고
    • Altered SK3/KCa2.3mediated migration in adenomatous polyposis coli (Apc) mutated mouse colon epithelial cells
    • Potier, M. et al. Altered SK3/KCa2.3mediated migration in adenomatous polyposis coli (Apc) mutated mouse colon epithelial cells. Biochem. Biophys. Res. Commun. 397, 42-47 (2010).
    • (2010) Biochem. Biophys. Res. Commun , vol.397 , pp. 42-47
    • Potier, M.1
  • 90
    • 70449526548 scopus 로고    scopus 로고
    • KCa2.3 channel-dependent hyperpolarization increases melanoma cell motility
    • Chantome, A. et al. KCa2.3 channel-dependent hyperpolarization increases melanoma cell motility. Exp. Cell Res. 315, 3620-3630 (2009).
    • (2009) Exp. Cell Res , vol.315 , pp. 3620-3630
    • Chantome, A.1
  • 91
    • 33845185801 scopus 로고    scopus 로고
    • Identification of SK3 channel as a new mediator of breast cancer cell migration
    • Potier, M. et al. Identification of SK3 channel as a new mediator of breast cancer cell migration. Mol. Cancer Ther. 5, 2946-2953 (2006).
    • (2006) Mol. Cancer Ther , vol.5 , pp. 2946-2953
    • Potier, M.1
  • 92
    • 81155123770 scopus 로고    scopus 로고
    • New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis
    • Girault, A. et al. New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis. Curr. Cancer Drug Targets 11, 1111-1125 (2011).
    • (2011) Curr. Cancer Drug Targets , vol.11 , pp. 1111-1125
    • Girault, A.1
  • 93
    • 84865412158 scopus 로고    scopus 로고
    • Human ether agogo K+ channel 1 (hEag1) regulates MDAMB231 breast cancer cell migration through Orai1dependent calcium entry
    • Hammadi, M. et al. Human ether agogo K+ channel 1 (hEag1) regulates MDAMB231 breast cancer cell migration through Orai1dependent calcium entry. J. Cell. Physiol. 227, 3837-3846 (2012).
    • (2012) J. Cell. Physiol , vol.227 , pp. 3837-3846
    • Hammadi, M.1
  • 94
    • 84881452627 scopus 로고    scopus 로고
    • Pivotal role of the lipid raft SK3Orai1 complex in human cancer cell migration and bone metastases
    • Chantome, A. et al. Pivotal role of the lipid raft SK3Orai1 complex in human cancer cell migration and bone metastases. Cancer Res. 73, 4852-4861 (2013).
    • (2013) Cancer Res , vol.73 , pp. 4852-4861
    • Chantome, A.1
  • 95
    • 80053332288 scopus 로고    scopus 로고
    • Cell volume homeostatic mechanisms: Effectors and signalling pathways
    • Hoffmann, E. K. & Pedersen, S. F. Cell volume homeostatic mechanisms: effectors and signalling pathways. Acta Physiol. (Oxf.) 202, 465-485 (2011).
    • (2011) Acta Physiol. (Oxf. , vol.202 , pp. 465-485
    • Hoffmann, E.K.1    Pedersen, S.F.2
  • 96
    • 83755182914 scopus 로고    scopus 로고
    • Ion channels involved in cell volume regulation: Effects on migration, proliferation, and programmed cell death in non adherent EAT cells and adherent ELA cells
    • Hoffmann, E. K. Ion channels involved in cell volume regulation: effects on migration, proliferation, and programmed cell death in non adherent EAT cells and adherent ELA cells. Cell Physiol. Biochem. 28, 1061-1078 (2011).
    • (2011) Cell Physiol. Biochem , vol.28 , pp. 1061-1078
    • Hoffmann, E.K.1
  • 97
    • 84940619230 scopus 로고
    • Cell volume regulation in renal cortical cells
    • Völkl, H., Paulmichl, M. & Lang, F. Cell volume regulation in renal cortical cells. Ren Physiol. Biochem. 11, 158-173 (1988).
    • (1988) Ren Physiol. Biochem , vol.11 , pp. 158-173
    • Völkl, H.1    Paulmichl, M.2    Lang, F.3
  • 98
    • 0027298477 scopus 로고
    • Involvement of K+ channels in the quercetin-induced inhibition of neuroblastoma cell growth
    • Rouzaire-Dubois, B., Gerard, V. & Dubois, J. M. Involvement of K+ channels in the quercetin-induced inhibition of neuroblastoma cell growth. Pflugers Arch. 423, 202-205 (1993).
    • (1993) Pflugers Arch , vol.423 , pp. 202-205
    • Rouzaire-Dubois, B.1    Gerard, V.2    Dubois, J.M.3
  • 99
    • 4344671278 scopus 로고    scopus 로고
    • The influence of cell volume changes on tumour cell proliferation
    • Dubois, J.M. & Rouzaire-Dubois, B. The influence of cell volume changes on tumour cell proliferation. Eur. Biophys. J. 33, 227-232 (2004).
    • (2004) Eur. Biophys. J , vol.33 , pp. 227-232
    • Dubois, J.M.1    Rouzaire-Dubois, B.2
  • 100
    • 84865098860 scopus 로고    scopus 로고
    • Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics
    • Huang, X. et al. Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev. 26, 1780-1796 (2012).
    • (2012) Genes Dev , vol.26 , pp. 1780-1796
    • Huang, X.1
  • 101
    • 0028323189 scopus 로고
    • Rat aortic smooth muscle cells expressing charybdotoxin-sensitive potassium channels exhibit enhanced proliferative responses
    • Neylon, C. B., Avdonin, P. V., Larsen, M. A. & Bobik, A. Rat aortic smooth muscle cells expressing charybdotoxin-sensitive potassium channels exhibit enhanced proliferative responses. Clin. Exp. Pharmacol. Physiol. 21, 117-120 (1994).
    • (1994) Clin. Exp. Pharmacol. Physiol , vol.21 , pp. 117-120
    • Neylon, C.B.1    Avdonin, P.V.2    Larsen, M.A.3    Bobik, A.4
  • 102
    • 0031595446 scopus 로고    scopus 로고
    • Blockade of Ca2+-activated K+ channels inhibits proliferation of human endothelial cells induced by basic fibroblast growth factor
    • Wiecha, J. et al. Blockade of Ca2+-activated K+ channels inhibits proliferation of human endothelial cells induced by basic fibroblast growth factor. J. Vasc. Res. 35, 363-371 (1998).
    • (1998) J. Vasc. Res , vol.35 , pp. 363-371
    • Wiecha, J.1
  • 103
    • 0035046273 scopus 로고    scopus 로고
    • Vascular endothelial growth factora activates Ca2+-activated K+ channels in human endothelial cells in culture
    • Faehling, M., Koch, E. D., Raithel, J., Trischler, G. & Waltenberger, J. Vascular endothelial growth factora activates Ca2+-activated K+ channels in human endothelial cells in culture. Int. J. Biochem. Cell Biol. 33, 337-346 (2001).
    • (2001) Int. J. Biochem. Cell Biol , vol.33 , pp. 337-346
    • Faehling, M.1    Koch, E.D.2    Raithel, J.3    Trischler, G.4    Waltenberger, J.5
  • 104
    • 0036461561 scopus 로고    scopus 로고
    • Potassium channels and vascular proliferation
    • Neylon, C. B. Potassium channels and vascular proliferation. Vasc. Pharmacol. 38, 35-41 (2002).
    • (2002) Vasc. Pharmacol , vol.38 , pp. 35-41
    • Neylon, C.B.1
  • 105
    • 77952348815 scopus 로고    scopus 로고
    • Cell cycle-dependent expression of Kv3.4 channels modulates proliferation of human uterine artery smooth muscle cells
    • Miguel-Velado, E. et al. Cell cycle-dependent expression of Kv3.4 channels modulates proliferation of human uterine artery smooth muscle cells. Cardiovasc. Res. 86, 383-391 (2010).
    • (2010) Cardiovasc. Res , vol.86 , pp. 383-391
    • Miguel-Velado, E.1
  • 106
    • 78751507980 scopus 로고    scopus 로고
    • Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers
    • Cheong, A. et al. Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers. Cardiovasc. Res. 89, 282-289 (2011).
    • (2011) Cardiovasc. Res , vol.89 , pp. 282-289
    • Cheong, A.1
  • 107
    • 84860222580 scopus 로고    scopus 로고
    • Kv1.3 channels can modulate cell proliferation during phenotypic switch by an ion-flux independent mechanism
    • Cidad, P. et al. Kv1.3 channels can modulate cell proliferation during phenotypic switch by an ion-flux independent mechanism. Arterioscler. Thromb. Vasc. Biol. 32, 1299-1307 (2012).
    • (2012) Arterioscler. Thromb. Vasc. Biol , vol.32 , pp. 1299-1307
    • Cidad, P.1
  • 108
    • 84878408383 scopus 로고    scopus 로고
    • The intermediate-conductance calcium-activated potassium channel KCa3.1 regulates vascular smooth muscle cell proliferation via controlling calcium-dependent signaling
    • Bi, D. et al. The intermediate-conductance calcium-activated potassium channel KCa3.1 regulates vascular smooth muscle cell proliferation via controlling calcium-dependent signaling. J Biol Chem, 15843-15853 (2013).
    • (2013) J Biol Chem , pp. 15843-15853
    • Bi, D.1
  • 109
    • 84873864396 scopus 로고    scopus 로고
    • KCa3.1 channels mediate the increase of cell migration and proliferation by advanced glycation endproducts in cultured rat vascular smooth muscle cells
    • Zhao, L. M., Su, X. L., Wang, Y., Li, G. R. & Deng, X. L. KCa3.1 channels mediate the increase of cell migration and proliferation by advanced glycation endproducts in cultured rat vascular smooth muscle cells. Lab. Invest. 93, 159-167 (2013).
    • (2013) Lab. Invest , vol.93 , pp. 159-167
    • Zhao, L.M.1    Su, X.L.2    Wang, Y.3    Li, G.R.4    Deng, X.L.5
  • 110
    • 0034796370 scopus 로고    scopus 로고
    • Changes in the K+ current-density of MCF7 cells during progression through the cell cycle: Possible involvement of a hether.agogo K+ channel
    • Ouadid-Ahidouch, H. et al. Changes in the K+ current-density of MCF7 cells during progression through the cell cycle: Possible involvement of a hether.agogo K+ channel. Recept. Channels 7, 345-356 (2001).
    • (2001) Recept. Channels , vol.7 , pp. 345-356
    • Ouadid-Ahidouch, H.1
  • 111
    • 80051628334 scopus 로고    scopus 로고
    • Pronounced hypoxia in models of murine and human leukemia: High efficacy of hypoxia-activated prodrug PR104
    • Benito, J. et al. Pronounced hypoxia in models of murine and human leukemia: High efficacy of hypoxia-activated prodrug PR104. PLoS ONE 6, e23108 (2011).
    • (2011) PLoS ONE , vol.6
    • Benito, J.1
  • 112
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 114
    • 0021271521 scopus 로고
    • Voltage-gated K+ channels in human T lymphocytes: A role in mitogenesis?
    • DeCoursey, T. E., Chandy, K. G., Gupta, S. & Cahalan, M. D. Voltage-gated K+ channels in human T lymphocytes: A role in mitogenesis? Nature 307, 465-468 (1984).
    • (1984) Nature , vol.307 , pp. 465-468
    • Decoursey, T.E.1    Chandy, K.G.2    Gupta, S.3    Cahalan, M.D.4
  • 115
    • 70449718851 scopus 로고    scopus 로고
    • Bioelectric controls of cell proliferation: Ion channels, membrane voltage and the cell cycle
    • Blackiston, D. J., McLaughlin, K. A. & Levin, M. Bioelectric controls of cell proliferation: ion channels, membrane voltage and the cell cycle. Cell Cycle 8, 3519-3528 (2009).
    • (2009) Cell Cycle , vol.8 , pp. 3519-3528
    • Blackiston, D.J.1    McLaughlin, K.A.2    Levin, M.3
  • 116
    • 70349162817 scopus 로고    scopus 로고
    • The functional network of ion channels in T lymphocytes
    • Cahalan, M. D. & Chandy, K. G. The functional network of ion channels in T lymphocytes. Immunol. Rev. 231, 59-87 (2009).
    • (2009) Immunol. Rev , vol.231 , pp. 59-87
    • Cahalan, M.D.1    Chandy, K.G.2
  • 117
    • 77949424378 scopus 로고    scopus 로고
    • Intermediate ca2+-sensitive k+ channels are necessary for prolactin-induced proliferation in breast cancer cells
    • Faouzi, M., Chopin, V., Ahidouch, A. & Ouadid- Ahidouch, H. Intermediate Ca2+-sensitive K+ channels are necessary for prolactin-induced proliferation in breast cancer cells. J. Membr. Biol. 234, 47-56 (2010).
    • (2010) J. Membr. Biol , vol.234 , pp. 47-56
    • Faouzi, M.1    Chopin, V.2    Ahidouch, A.3    Ouadid-Ahidouch, H.4
  • 118
    • 65349099293 scopus 로고    scopus 로고
    • Intermediate-conductance Ca2+- activated K+ channels (IKCa1) regulate human prostate cancer cell proliferation through a close control of calcium entry
    • Lallet-Daher, H. et al. Intermediate-conductance Ca2+- activated K+ channels (IKCa1) regulate human prostate cancer cell proliferation through a close control of calcium entry. Oncogene 28, 1792-1806 (2009).
    • (2009) Oncogene , vol.28 , pp. 1792-1806
    • Lallet-Daher, H.1
  • 119
    • 77949327468 scopus 로고    scopus 로고
    • Ion channels and the hallmarks of cancer
    • Prevarskaya, N., Skryma, R. & Shuba, Y. Ion channels and the hallmarks of cancer. Trends Mol. Med. 16, 107-121 (2010).
    • (2010) Trends Mol. Med , vol.16 , pp. 107-121
    • Prevarskaya, N.1    Skryma, R.2    Shuba, Y.3
  • 120
    • 79951905351 scopus 로고    scopus 로고
    • Controlling the cell cycle: The role of calcium/ calmodulin-stimulated protein kinases i and II
    • Skelding, K. A., Rostas, J. A. P. & Verrills, N. M. Controlling the cell cycle: The role of calcium/ calmodulin-stimulated protein kinases I and II. Cell Cycle 10, 631-639 (2011).
    • (2011) Cell Cycle , vol.10 , pp. 631-639
    • Skelding, K.A.1    Rostas, J.A.P.2    Verrills, N.M.3
  • 121
    • 0347949547 scopus 로고    scopus 로고
    • Regulation of cell cycle progression by calcium/calmodulin-dependent pathways
    • Kahl, C. R. & Means, A. R. Regulation of cell cycle progression by calcium/calmodulin-dependent pathways. Endocr. Rev. 24, 719-736 (2003).
    • (2003) Endocr. Rev , vol.24 , pp. 719-736
    • Kahl, C.R.1    Means, A.R.2
  • 122
    • 16544372024 scopus 로고    scopus 로고
    • The 2Pdomain K+ channels: Role in apoptosis and tumorigenesis
    • Patel, A. J. & Lazdunski, M. The 2Pdomain K+ channels: role in apoptosis and tumorigenesis. Pflugers Arch. 448, 261-273 (2004).
    • (2004) Pflugers Arch , vol.448 , pp. 261-273
    • Patel, A.J.1    Lazdunski, M.2
  • 123
    • 84869210513 scopus 로고    scopus 로고
    • Differential role of IK and BK potassium channels as mediators of intrinsic and extrinsic apoptotic cell death
    • McFerrin, M. B., Turner, K. L., Cuddapah, V. A. & Sontheimer, H. Differential role of IK and BK potassium channels as mediators of intrinsic and extrinsic apoptotic cell death. Am. J. Physiol. Cell Physiol. 303, C1070-C1078 (2012).
    • (2012) Am. J. Physiol. Cell Physiol , vol.303
    • McFerrin, M.B.1    Turner, K.L.2    Cuddapah, V.A.3    Sontheimer, H.4
  • 124
    • 81155132254 scopus 로고    scopus 로고
    • Intracellular K+ concentration decrease is not obligatory for apoptosis
    • Borjesson, S. I., Englund, U. H., Asif, M. H., Willander, M. & Elinder, F. Intracellular K+ concentration decrease is not obligatory for apoptosis. J. Biol. Chem. 286, 39823-39828 (2011).
    • (2011) J. Biol. Chem , vol.286 , pp. 39823-39828
    • Borjesson, S.I.1    Englund, U.H.2    Asif, M.H.3    Willander, M.4    Elinder, F.5
  • 125
    • 79959995937 scopus 로고    scopus 로고
    • Ion channel inhibitors block caspase activation by mechanisms other than restoring intracellular potassium concentration
    • Benitez-Rangel, E., Garcia, L., Namorado, M. C., Reyes, J. L. & Guerrero-Hernandez, A. Ion channel inhibitors block caspase activation by mechanisms other than restoring intracellular potassium concentration. Cell Death Dis. 2, e113 (2011).
    • (2011) Cell Death Dis , vol.2
    • Benitez-Rangel, E.1    Garcia, L.2    Namorado, M.C.3    Reyes, J.L.4    Guerrero-Hernandez, A.5
  • 126
    • 0344493811 scopus 로고    scopus 로고
    • Nicorandil inhibits oxidative stress-induced apoptosis in cardiac myocytes through activation of mitochondrial ATP-sensitive potassium channels and a nitrate-like effect
    • Nagata, K. et al. Nicorandil inhibits oxidative stress-induced apoptosis in cardiac myocytes through activation of mitochondrial ATP-sensitive potassium channels and a nitrate-like effect. J. Mol. Cell Cardiol 35, 1505-1512 (2003).
    • (2003) J. Mol. Cell Cardiol , vol.35 , pp. 1505-1512
    • Nagata, K.1
  • 127
    • 56549105168 scopus 로고    scopus 로고
    • Glibenclamide exerts an antitumor activity through reactive oxygen species-cjun NH2- terminal kinase pathway in human gastric cancer cell line MGC803
    • Qian, X. et al. Glibenclamide exerts an antitumor activity through reactive oxygen species-cjun NH2- terminal kinase pathway in human gastric cancer cell line MGC803. Biochem. Pharmacol. 76, 1705-1715 (2008).
    • (2008) Biochem. Pharmacol , vol.76 , pp. 1705-1715
    • Qian, X.1
  • 128
    • 79951513548 scopus 로고    scopus 로고
    • The protective roles of mitochondrial ATP-sensitive potassium channels during hypoxia- ischemia-reperfusion in brain
    • Wang, L. et al. The protective roles of mitochondrial ATP-sensitive potassium channels during hypoxia- ischemia-reperfusion in brain. Neurosci. Lett. 491, 63-67 (2011).
    • (2011) Neurosci. Lett , vol.491 , pp. 63-67
    • Wang, L.1
  • 129
    • 84864880941 scopus 로고    scopus 로고
    • Mitochondrial ROMK channel is a molecular component of mitoKATP
    • Foster, D. B. et al. Mitochondrial ROMK channel is a molecular component of mitoKATP. Circ. Res. 111, 446-454 (2012).
    • (2012) Circ. Res , vol.111 , pp. 446-454
    • Foster, D.B.1
  • 130
    • 0034737472 scopus 로고    scopus 로고
    • TASK3, a new member of the tandem pore K+ channel family
    • Kim, Y., Bang, H. & Kim, D. TASK3, a new member of the tandem pore K+ channel family. J. Biol. Chem. 275, 9340-9347 (2000).
    • (2000) J. Biol. Chem , vol.275 , pp. 9340-9347
    • Kim, Y.1    Bang, H.2    Kim, D.3
  • 131
    • 0038587789 scopus 로고    scopus 로고
    • Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene
    • Mu, D. et al. Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell 3, 297-302 (2003).
    • (2003) Cancer Cell , vol.3 , pp. 297-302
    • Mu, D.1
  • 132
    • 84863163077 scopus 로고    scopus 로고
    • Reduction of breast cancer cell migration via upregulation of TASK3 two-pore domain K+ channel
    • Lee, G. W. et al. Reduction of breast cancer cell migration via upregulation of TASK3 two-pore domain K+ channel. Acta Physiol. (Oxf.) 204, 513-524 (2012).
    • (2012) Acta Physiol. (Oxf. , vol.204 , pp. 513-524
    • Lee, G.W.1
  • 133
    • 0038271812 scopus 로고    scopus 로고
    • Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function
    • Pei, L. et al. Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function. Proc. Natl Acad. Sci. USA 100, 7803-7807 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 7803-7807
    • Pei, L.1
  • 134
    • 0041856116 scopus 로고    scopus 로고
    • K+-dependent cerebellar granule neuron apoptosis role of task leak k+ channels
    • Lauritzen, I. et al. K+-dependent cerebellar granule neuron apoptosis. Role of TASK leak K+ channels. J. Biol. Chem. 278, 32068-32076 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 32068-32076
    • Lauritzen, I.1
  • 135
    • 43149120041 scopus 로고    scopus 로고
    • The two-pore domain potassium channel TASK3 functionally impacts glioma cell death
    • Meuth, S. G. et al. The two-pore domain potassium channel TASK3 functionally impacts glioma cell death. J. Neurooncol 87, 263-270 (2008).
    • (2008) J. Neurooncol , vol.87 , pp. 263-270
    • Meuth, S.G.1
  • 136
    • 41049085767 scopus 로고    scopus 로고
    • Mitochondrial expression of the two-pore domain TASK3 channels in malignantly transformed and non-malignant human cells
    • Rusznak, Z. et al. Mitochondrial expression of the two-pore domain TASK3 channels in malignantly transformed and non-malignant human cells. Virchows Arch. 452, 415-426 (2008).
    • (2008) Virchows Arch , vol.452 , pp. 415-426
    • Rusznak, Z.1
  • 137
    • 84876762744 scopus 로고    scopus 로고
    • Expression and prognostic significance of the oncogenic K2P potassium channel KCNK9 (TASK3) in ovarian carcinoma
    • Innamaa, A. et al. Expression and prognostic significance of the oncogenic K2P potassium channel KCNK9 (TASK3) in ovarian carcinoma. Anticancer Res. 33, 1401-1408 (2013).
    • (2013) Anticancer Res , vol.33 , pp. 1401-1408
    • Innamaa, A.1
  • 138
    • 0036066182 scopus 로고    scopus 로고
    • Actinomycin Dinduced apoptosis involves the potassium channel Kv1.3
    • Bock, J., Szabo, I., Jekle, A. & Gulbins, E. Actinomycin Dinduced apoptosis involves the potassium channel Kv1.3. Biochem. Biophys. Res. Commun. 295, 526-531 (2002).
    • (2002) Biochem. Biophys. Res. Commun , vol.295 , pp. 526-531
    • Bock, J.1    Szabo, I.2    Jekle, A.3    Gulbins, E.4
  • 139
    • 51149089082 scopus 로고    scopus 로고
    • Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes
    • Szabo, I. et al. Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. Proc. Natl Acad. Sci. USA 105, 14861-14866 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 14861-14866
    • Szabo, I.1
  • 140
    • 77953758600 scopus 로고    scopus 로고
    • Role of Kv1.3 mitochondrial potassium channel in apoptotic signalling in lymphocytes
    • Gulbins, E., Sassi, N., Grassme, H., Zoratti, M. & Szabo, I. Role of Kv1.3 mitochondrial potassium channel in apoptotic signalling in lymphocytes. Biochim. Biophys. Acta 1797, 1251-1259 (2010).
    • (2010) Biochim. Biophys. Acta , vol.1797 , pp. 1251-1259
    • Gulbins, E.1    Sassi, N.2    Grassme, H.3    Zoratti, M.4    Szabo, I.5
  • 141
    • 84863473765 scopus 로고    scopus 로고
    • Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells
    • Leanza, L. et al. Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells. EMBO Mol. Med. 4, 577-593 (2012).
    • (2012) EMBO Mol. Med , vol.4 , pp. 577-593
    • Leanza, L.1
  • 142
    • 84870410761 scopus 로고    scopus 로고
    • Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels
    • Leanza, L., Zoratti, M., Gulbins, E. & Szabo, I. Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels. Curr. Med. Chem. 19, 5394-5404 (2012).
    • (2012) Curr. Med. Chem , vol.19 , pp. 5394-5404
    • Leanza, L.1    Zoratti, M.2    Gulbins, E.3    Szabo, I.4
  • 143
    • 77953777012 scopus 로고    scopus 로고
    • An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1
    • Sassi, N. et al. An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1. Biochim. Biophys. Acta 1797, 1260-1267 (2010).
    • (2010) Biochim. Biophys. Acta , vol.1797 , pp. 1260-1267
    • Sassi, N.1
  • 144
    • 78751689287 scopus 로고    scopus 로고
    • Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers
    • Pillozzi, S. et al. Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers. Blood 117, 902-914 (2011).
    • (2011) Blood , vol.117 , pp. 902-914
    • Pillozzi, S.1
  • 145
    • 84863569591 scopus 로고    scopus 로고
    • Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: Role for ATP-sensitive K+ channels and endoplasmic reticulum stress
    • Suzuki, Y. et al. Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: role for ATP-sensitive K+ channels and endoplasmic reticulum stress. Int. J. Oncol. 41, 465-475 (2012).
    • (2012) Int. J. Oncol , vol.41 , pp. 465-475
    • Suzuki, Y.1
  • 146
    • 77951758528 scopus 로고    scopus 로고
    • HERG K+ channel related chemosensitivity to sparfloxacin in colon cancer cells
    • Gong, J. H., Liu, X. J., Shang, B. Y., Chen, S. Z. & Zhen, Y. S. HERG K+ channel related chemosensitivity to sparfloxacin in colon cancer cells. Oncol. Rep. 23, 1747-1756 (2010).
    • (2010) Oncol. Rep , vol.23 , pp. 1747-1756
    • Gong, J.H.1    Liu, X.J.2    Shang, B.Y.3    Chen, S.Z.4    Zhen, Y.S.5
  • 147
    • 65649088361 scopus 로고    scopus 로고
    • State-dependent block of HERG potassium channels by Rroscovitine: Implications for cancer therapy
    • Ganapathi, S. B., Kester, M. & Elmslie, K. S. State-dependent block of HERG potassium channels by Rroscovitine: implications for cancer therapy. Am. J. Physiol. Cell Physiol. 296, C701-C710 (2009).
    • (2009) Am. J. Physiol. Cell Physiol , vol.296
    • Ganapathi, S.B.1    Kester, M.2    Elmslie, K.S.3
  • 148
    • 80053530300 scopus 로고    scopus 로고
    • Eag1 potassium channels as markers of cervical dysplasia
    • Ortiz, C. S. et al. Eag1 potassium channels as markers of cervical dysplasia. Oncol. Rep. 26, 1377-1383 (2011).
    • (2011) Oncol. Rep , vol.26 , pp. 1377-1383
    • Ortiz, C.S.1
  • 149
    • 21244476712 scopus 로고    scopus 로고
    • HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin
    • Chen, S. Z., Jiang, M. & Zhen, Y. S. HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin. Cancer Chemother. Pharmacol. 56, 212-220 (2005).
    • (2005) Cancer Chemother. Pharmacol , vol.56 , pp. 212-220
    • Chen, S.Z.1    Jiang, M.2    Zhen, Y.S.3
  • 150
    • 84862958910 scopus 로고    scopus 로고
    • Human etheragogorelated gene expression is essential for cisplatin to induce apoptosis in human gastric cancer
    • Zhang, R. et al. Human etheragogorelated gene expression is essential for cisplatin to induce apoptosis in human gastric cancer. Oncol. Rep. 27, 433-440 (2012).
    • (2012) Oncol. Rep , vol.27 , pp. 433-440
    • Zhang, R.1
  • 151
    • 78650589673 scopus 로고    scopus 로고
    • Eag and HERG potassium channels as novel therapeutic targets in cancer
    • Asher, V., Sowter, H., Shaw, R., Bali, A. & Khan, R. Eag and HERG potassium channels as novel therapeutic targets in cancer. World J. Surg. Oncol. 8, 113 (2010).
    • (2010) World J. Surg. Oncol , vol.8 , pp. 113
    • Asher, V.1    Sowter, H.2    Shaw, R.3    Bali, A.4    Khan, R.5
  • 152
    • 47749110251 scopus 로고    scopus 로고
    • An unexpected role for ion channels in brain tumor metastasis
    • Sontheimer, H. An unexpected role for ion channels in brain tumor metastasis. Exp. Biol. Med. (Maywood) 233, 779-791 (2008).
    • (2008) Exp. Biol. Med. (Maywood , vol.233 , pp. 779-791
    • Sontheimer, H.1
  • 153
    • 84890027846 scopus 로고    scopus 로고
    • A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors
    • Jahchan, N. S. et al. A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discovery http://dx.doi. org/10.1158/21598290.CD130183 (2013).
    • (2013) Cancer Discovery
    • Jahchan, N.S.1
  • 154
    • 84866625373 scopus 로고    scopus 로고
    • Physical and functional interaction of KV10.1 with Rabaptin5 impacts ion channel trafficking
    • Ninkovic, M., Mitkovski, M., Kohl, T., Stmer, W. & Pardo, L. A. Physical and functional interaction of KV10.1 with Rabaptin5 impacts ion channel trafficking. FEBS Lett. 586, 3077-3084 (2012).
    • (2012) FEBS Lett , vol.586 , pp. 3077-3084
    • Ninkovic, M.1    Mitkovski, M.2    Kohl, T.3    Stmer, W.4    Pardo, L.A.5
  • 155
    • 84871779118 scopus 로고    scopus 로고
    • Cortactin controls surface expression of the voltage-gated potassium channel KV10.1
    • Herrmann, S., Ninkovic, M., Kohl, T., Linczi, E. & Pardo, L. A. Cortactin controls surface expression of the voltage-gated potassium channel KV10.1. J. Biol. Chem. 287, 44151-44163 (2012).
    • (2012) J. Biol. Chem , vol.287 , pp. 44151-44163
    • Herrmann, S.1    Ninkovic, M.2    Kohl, T.3    Linczi, E.4    Pardo, L.A.5
  • 156
    • 4944252457 scopus 로고    scopus 로고
    • Ether gogo potassium channels as human cervical cancer markers
    • Farias, L. M. B. et al. Ether gogo potassium channels as human cervical cancer markers. Cancer Res. 64, 6996-7001 (2004).
    • (2004) Cancer Res , vol.64 , pp. 6996-7001
    • Farias, L.M.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.